{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T19:10:36Z","timestamp":1792782636491,"version":"4.5.0"},"reference-count":17,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T00:00:00Z","timestamp":1783036800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T00:00:00Z","timestamp":1790208000000},"content-version":"vor","delay-in-days":83,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"name":"Akershus University Hospital","id":[{"id":"https:\/\/ror.org\/0331wat71","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int J Colorectal Dis"],"DOI":"10.1007\/s00384-026-05191-x","type":"journal-article","created":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T14:56:12Z","timestamp":1783090572000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Long-term disease-free survival in young-onset rectal cancer patients surgically treated with curative intent: a retrospective cohort study"],"prefix":"10.1007","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-3431-8569","authenticated-orcid":false,"given":"Oddne Fjellstad","family":"Johnsen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rolf Nerem","family":"Riis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastian","family":"Meltzer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne Hansen","family":"Ree","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Knut Magne","family":"Augestad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,7,3]]},"reference":[{"issue":"4","key":"5191_CR1","doi-asserted-by":"publisher","first-page":"230","DOI":"10.1038\/s41571-020-00445-1","volume":"18","author":"N Akimoto","year":"2021","unstructured":"Akimoto N, Ugai T, Zhong R, Hamada T, Fujiyoshi K, Giannakis M et al (2021) Rising incidence of early-onset colorectal cancer - a call to action. Nat Rev Clin Oncol 18(4):230\u2013243","journal-title":"Nat Rev Clin Oncol"},{"issue":"3","key":"5191_CR2","first-page":"145","volume":"70","author":"RL Siegel","year":"2020","unstructured":"Siegel RL, Miller KD, Goding Sauer A, Fedewa SA, Butterly LF, Anderson JC et al (2020) Colorectal cancer statistics, 2020. CA Cancer J Clin 70(3):145\u2013164","journal-title":"CA Cancer J Clin"},{"issue":"1","key":"5191_CR3","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-54972-3","volume":"14","author":"B Ren","year":"2024","unstructured":"Ren B, Yang Y, Lv Y, Liu K (2024) Survival outcome and prognostic factors for early-onset and late-onset metastatic colorectal cancer: a population based study from SEER database. Sci Rep 14(1):4377","journal-title":"Sci Rep"},{"issue":"11","key":"5191_CR4","doi-asserted-by":"publisher","first-page":"e2130433","DOI":"10.1001\/jamanetworkopen.2021.30433","volume":"4","author":"EM Montminy","year":"2021","unstructured":"Montminy EM, Zhou M, Maniscalco L, Penrose H, Yen T, Patel SG et al (2021) Trends in the incidence of early-onset colorectal adenocarcinoma among Black and White US residents aged 40 to 49 years, 2000\u20132017. JAMA Netw Open 4(11):e2130433","journal-title":"JAMA Netw Open"},{"issue":"1","key":"5191_CR5","doi-asserted-by":"publisher","first-page":"182","DOI":"10.62347\/KTIW8135","volume":"14","author":"MH Tsai","year":"2024","unstructured":"Tsai MH, Moore JX, Cabral DN, Rogers CR, Cortes J (2024) Temporal trends in early-onset colorectal cancer incidence (2000\u20132020) by age group and five geographic regions in the state of Georgia. Am J Cancer Res 14(1):182\u2013191","journal-title":"Am J Cancer Res"},{"key":"5191_CR6","doi-asserted-by":"publisher","DOI":"10.1093\/bjsopen\/zrad030","author":"O Waddell","year":"2023","unstructured":"Waddell O, McLauchlan J, McCombie A, Glyn T, Frizelle F (2023) Quality of life in early-onset colorectal cancer patients: systematic review. BJS Open 7(3).\u00a0https:\/\/doi.org\/10.1093\/bjsopen\/zrad030","journal-title":"BJS Open"},{"issue":"10","key":"5191_CR7","doi-asserted-by":"publisher","first-page":"1820","DOI":"10.1136\/gutjnl-2018-317592","volume":"68","author":"FE Vuik","year":"2019","unstructured":"Vuik FE, Nieuwenburg SA, Bardou M, Lansdorp-Vogelaar I, Dinis-Ribeiro M, Bento MJ et al (2019) Increasing incidence of colorectal cancer in young adults in Europe over the last 25 years. Gut 68(10):1820\u20131826","journal-title":"Gut"},{"key":"5191_CR8","unstructured":"Wibe A ea. Kreft i tykktarm og endetarm: Handlingsprogram: Helsedirektoratet; first published 2010 [updated 2024 January 31]. Available from: https:\/\/www.helsedirektoratet.no\/retningslinjer\/kreft-i-tykktarm-og-endetarm-handlingsprogram. Accessed 29 Apr 2025"},{"key":"5191_CR9","volume-title":"TNM classification of malignant tumours","author":"JD Brierley","year":"2017","unstructured":"Brierley JD, Gospodarowicz MK, Wittekind C (2017) TNM classification of malignant tumours. Wiley"},{"issue":"16","key":"5191_CR10","doi-asserted-by":"publisher","first-page":"2142","DOI":"10.1200\/JCO.2010.34.4473","volume":"29","author":"B Glimelius","year":"2011","unstructured":"Glimelius B, Beets-Tan R, Blomqvist L, Brown G, Nagtegaal I, Pahlman L et al (2011) Mesorectal fascia instead of circumferential resection margin in preoperative staging of rectal cancer. J Clin Oncol 29(16):2142\u20132143","journal-title":"J Clin Oncol"},{"issue":"1","key":"5191_CR11","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1007\/s00423-024-03237-8","volume":"409","author":"E Mariusdottir","year":"2024","unstructured":"Mariusdottir E, Jorgren F, Saeed M, Wikstrom J, Lydrup ML, Buchwald P (2024) Hartmann\u2019s procedure in rectal cancer surgery is often an intraoperative decision: a retrospective multicenter study. Langenbecks Arch Surg 409(1):55","journal-title":"Langenbecks Arch Surg"},{"key":"5191_CR12","doi-asserted-by":"publisher","DOI":"10.1016\/j.xcrm.2024.101737","author":"G Mauri","year":"2024","unstructured":"Mauri G, Patelli G, Sartore-Bianchi A, Abrignani S, Bodega B, Marsoni S et al (2024) Early-onset cancers: biological bases and clinical implications. Cell Rep Med 5(9):101737. https:\/\/doi.org\/10.1016\/j.xcrm.2024.101737","journal-title":"Cell Rep Med"},{"issue":"9","key":"5191_CR13","doi-asserted-by":"publisher","first-page":"865","DOI":"10.1001\/jamasurg.2021.2380","volume":"156","author":"R Collaborative","year":"2021","unstructured":"Collaborative R, Zaborowski AM, Abdile A, Adamina M, Aigner F, d\u2019Allens L et al (2021) Characteristics of early-onset vs late-onset colorectal cancer: a review. JAMA Surg 156(9):865\u2013874","journal-title":"JAMA Surg"},{"issue":"3","key":"5191_CR14","doi-asserted-by":"publisher","first-page":"262","DOI":"10.1016\/S2468-1253(21)00426-X","volume":"7","author":"SG Patel","year":"2022","unstructured":"Patel SG, Karlitz JJ, Yen T, Lieu CH, Boland CR (2022) The rising tide of early-onset colorectal cancer: a comprehensive review of epidemiology, clinical features, biology, risk factors, prevention, and early detection. Lancet Gastroenterol Hepatol 7(3):262\u2013274","journal-title":"Lancet Gastroenterol Hepatol"},{"issue":"3","key":"5191_CR15","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1002\/ijc.11540","volume":"108","author":"EK Wei","year":"2004","unstructured":"Wei EK, Giovannucci E, Wu K, Rosner B, Fuchs CS, Willett WC et al (2004) Comparison of risk factors for colon and rectal cancer. Int J Cancer 108(3):433\u2013442","journal-title":"Int J Cancer"},{"issue":"3","key":"5191_CR16","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1111\/codi.16367","volume":"25","author":"U Saeed","year":"2023","unstructured":"Saeed U, Myklebust T\u00c5, Robsahm TE, Kielland MF, M\u00f8ller B, Sk\u00e5lhegg BS et al (2023) Risk and survival in colorectal cancer with increasing body mass index: a nationwide population-based cohort study. Colorectal Dis 25(3):375\u2013385","journal-title":"Colorectal Dis"},{"issue":"5","key":"5191_CR17","doi-asserted-by":"publisher","first-page":"606","DOI":"10.1002\/bjs.11526","volume":"107","author":"AM Zaborowski","year":"2020","unstructured":"Zaborowski AM, Murphy B, Creavin B, Rogers AC, Kennelly R, Hanly A et al (2020) Clinicopathological features and oncological outcomes of patients with young-onset rectal cancer. Br J Surg 107(5):606\u2013612","journal-title":"Br J Surg"}],"container-title":["International Journal of Colorectal Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00384-026-05191-x","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00384-026-05191-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00384-026-05191-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T14:02:45Z","timestamp":1790258565000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00384-026-05191-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,3]]},"references-count":17,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["5191"],"URL":"https:\/\/doi.org\/10.1007\/s00384-026-05191-x","relation":{},"ISSN":["1432-1262"],"issn-type":[{"value":"1432-1262","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,3]]},"assertion":[{"value":"9 June 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 June 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 July 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The study is approved by the Regional Committee for Medical and Health Research Ethics (REK approval no. 832716). The hospital data protection officer approved the study protocol (PVO reference number 2024_87).","order":1,"name":"Ethics","label":"Ethics approval","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Passive consent was obtained in accordance with applicable Norwegian legislation.","order":2,"name":"Ethics","label":"Consent to participate","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"153"}}