{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T03:09:05Z","timestamp":1740107345775,"version":"3.37.3"},"reference-count":39,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2017,12,5]],"date-time":"2017-12-05T00:00:00Z","timestamp":1512432000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100011852","name":"Paracelsus Medical University","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100011852","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Z Gerontol Geriat"],"published-print":{"date-parts":[[2018,2]]},"DOI":"10.1007\/s00391-017-1351-y","type":"journal-article","created":{"date-parts":[[2017,12,5]],"date-time":"2017-12-05T13:09:37Z","timestamp":1512479377000},"page":"143-148","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Doping f\u00fcr das Gehirn","Doping for the brain"],"prefix":"10.1007","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6132-8670","authenticated-orcid":false,"given":"Bernhard","family":"Iglseder","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2017,12,5]]},"reference":[{"issue":"2","key":"1351_CR1","first-page":"118","volume":"6","author":"DA Baron","year":"2007","unstructured":"Baron DA, Martin DM, Abol Magd S (2007) Doping in sports and its spread to at-risk populations: an international review. World Psychiatry 6(2):118\u2013123","journal-title":"World Psychiatry"},{"issue":"8","key":"1351_CR2","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1007\/s00103-010-1105-0","volume":"53","author":"AG Franke","year":"2010","unstructured":"Franke AG, Lieb K (2010) Pharmacological neuroenhancement and brain doping : chances and risks. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 53(8):853\u2013859","journal-title":"Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz"},{"issue":"2","key":"1351_CR3","first-page":"E130","volume":"58","author":"S Majori","year":"2017","unstructured":"Majori S, Gazzani D, Pilati S, Paiano J, Sannino A, Ferrari S et\u00a0al (2017) Brain doping: stimulants use and misuse among a\u00a0sample of Italian college students. J\u00a0Prev Med Hyg 58(2):E130\u2013E140","journal-title":"J Prev Med Hyg"},{"key":"1351_CR4","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.phrs.2017.03.009","volume":"120","author":"MD Prakash","year":"2017","unstructured":"Prakash MD, Tangalakis K, Antonipillai J, Stojanovska L, Nurgali K, Apostolopoulos V (2017) Methamphetamine: effects on the brain, gut and immune system. Pharmacol Res 120:60\u201367","journal-title":"Pharmacol Res"},{"key":"1351_CR5","doi-asserted-by":"crossref","first-page":"80","DOI":"10.3389\/fpsyt.2017.00080","volume":"8","author":"JL Temple","year":"2017","unstructured":"Temple JL, Bernard C, Lipshultz SE, Czachor JD, Westphal JA, Mestre MA (2017) The safety of ingested caffeine: a comprehensive review. Front Psychiatry 8:80","journal-title":"Front Psychiatry"},{"issue":"1","key":"1351_CR6","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1006\/nimg.2001.0973","volume":"15","author":"TA Mulderink","year":"2002","unstructured":"Mulderink TA, Gitelman DR, Mesulam MM, Parrish TB (2002) On the use of caffeine as a\u00a0contrast booster for BOLD fMRI studies. Neuroimage 15(1):37\u201344","journal-title":"Neuroimage"},{"key":"1351_CR7","series-title":"Comparative Effectiveness Reviews, No. 188","doi-asserted-by":"crossref","DOI":"10.23970\/AHRQEPCCER188","volume-title":"Interventions to prevent age-related cognitive decline, mild cognitive impairment, and clinical alzheimer\u2019s-type dementia","author":"RL Kane","year":"2017","unstructured":"Kane RL, Butler M, Fink HA, Brasure M, Davila H, Desai P et al (2017) Interventions to prevent age-related cognitive decline, mild cognitive impairment, and clinical alzheimer\u2019s-type dementia. Comparative Effectiveness Reviews, No. 188. Agency for Healthcare Research and Quality, Rockville"},{"issue":"10","key":"1351_CR8","doi-asserted-by":"crossref","first-page":"2779","DOI":"10.1089\/ars.2010.3697","volume":"15","author":"DL Katz","year":"2011","unstructured":"Katz DL, Doughty K, Ali A (2011) Cocoa and chocolate in human health and disease. Antioxid Redox Signal 15(10):2779\u20132811","journal-title":"Antioxid Redox Signal"},{"issue":"4","key":"1351_CR9","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1007\/s00253-003-1527-9","volume":"64","author":"JV Smith","year":"2004","unstructured":"Smith JV, Luo Y (2004) Studies on molecular mechanisms of Ginkgo biloba extract. Appl Microbiol Biotechnol 64(4):465\u2013472","journal-title":"Appl Microbiol Biotechnol"},{"key":"1351_CR10","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD003120.pub2","author":"J Birks","year":"2009","unstructured":"Birks J, Grimley Evans J (2009) Ginkgo biloba for cognitive impairment and dementia. Cochrane Database Syst Rev. https:\/\/doi.org\/10.1002\/14651858.CD003120.pub2","journal-title":"Cochrane Database Syst Rev"},{"key":"1351_CR11","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1186\/s40780-015-0014-7","volume":"1","author":"M Hashiguchi","year":"2015","unstructured":"Hashiguchi M, Ohta Y, Shimizu M, Maruyama J, Mochizuki M (2015) Meta-analysis of the efficacy and safety of Ginkgo biloba extract for the treatment of dementia. J\u00a0Pharm Health Care Sci 1:14","journal-title":"J Pharm Health Care Sci"},{"key":"1351_CR12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jep.2016.12.005","volume":"195","author":"Q Yuan","year":"2017","unstructured":"Yuan Q, Wang CW, Shi J, Lin ZX (2017) Effects of ginkgo biloba on dementia: an overview of systematic reviews. J\u00a0Ethnopharmacol 195:1\u20139","journal-title":"J Ethnopharmacol"},{"issue":"21\u201322","key":"1351_CR13","doi-asserted-by":"crossref","first-page":"3797","DOI":"10.1007\/s00213-016-4414-7","volume":"233","author":"M Ota","year":"2016","unstructured":"Ota M, Matsuo J, Ishida I, Hattori K, Teraishi T, Tonouchi H et\u00a0al (2016) Effect of a\u00a0ketogenic meal on cognitive function in elderly adults: potential for cognitive enhancement. Psychopharmacology (Berl) 233(21\u201322):3797\u20133802","journal-title":"Psychopharmacology (Berl)"},{"issue":"1","key":"1351_CR14","doi-asserted-by":"crossref","first-page":"17","DOI":"10.2174\/1570159X13666150407225902","volume":"14","author":"FP Busardo","year":"2016","unstructured":"Busardo FP, Kyriakou C, Cipolloni L, Zaami S, Frati P (2016) From clinical application to cognitive enhancement: the example of methylphenidate. Curr Neuropharmacol 14(1):17\u201327","journal-title":"Curr Neuropharmacol"},{"issue":"37","key":"1351_CR15","doi-asserted-by":"crossref","first-page":"9547","DOI":"10.1523\/JNEUROSCI.1746-16.2016","volume":"36","author":"MD Rosenberg","year":"2016","unstructured":"Rosenberg MD, Zhang S, Hsu WT, Scheinost D, Finn ES, Shen X et\u00a0al (2016) Methylphenidate modulates functional network connectivity to enhance attention. J\u00a0Neurosci 36(37):9547\u20139557","journal-title":"J Neurosci"},{"issue":"9","key":"1351_CR16","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1176\/appi.ajp.2009.09040472","volume":"166","author":"MS Gould","year":"2009","unstructured":"Gould MS, Walsh BT, Munfakh JL, Kleinman M, Duan N, Olfson M et\u00a0al (2009) Sudden death and use of stimulant medications in youths. Am J Psychiatry 166(9):992\u20131001","journal-title":"Am J Psychiatry"},{"issue":"2","key":"1351_CR17","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.jaac.2011.11.008","volume":"51","author":"M Olfson","year":"2012","unstructured":"Olfson M, Huang C, Gerhard T, Winterstein AG, Crystal S, Allison PD et al (2012) Stimulants and cardiovascular events in youth with attention-deficit\/hyperactivity disorder. J\u00a0Am Acad Child Adolesc Psychiatry 51(2):147\u2013156","journal-title":"J Am Acad Child Adolesc Psychiatry"},{"issue":"Suppl 1","key":"1351_CR18","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1080\/10550490601082767","volume":"16","author":"SV Faraone","year":"2007","unstructured":"Faraone SV, Wilens TE, Petty C, Antshel K, Spencer T, Biederman J (2007) Substance use among ADHD adults: implications of late onset and subthreshold diagnoses. Am J Addict 16(Suppl 1):24\u201332 (quiz 3\u20134)","journal-title":"Am J Addict"},{"issue":"Suppl 11","key":"1351_CR19","first-page":"4","volume":"68","author":"TE Wilens","year":"2007","unstructured":"Wilens TE (2007) The nature of the relationship between attention-deficit\/hyperactivity disorder and substance use. J\u00a0Clin Psychiatry 68(Suppl 11):4\u20138","journal-title":"J Clin Psychiatry"},{"key":"1351_CR20","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1016\/j.neuropharm.2017.07.031","volume":"125","author":"ZA Cope","year":"2017","unstructured":"Cope ZA, Minassian A, Kreitner D, MacQueen DA, Milienne-Petiot M, Geyer MA et al (2017) Modafinil improves attentional performance in healthy, non-sleep deprived humans at doses not inducing hyperarousal across species. Neuropharmacology 125:254\u2013262","journal-title":"Neuropharmacology"},{"issue":"11","key":"1351_CR21","doi-asserted-by":"crossref","first-page":"1865","DOI":"10.1016\/j.euroneuro.2015.07.028","volume":"25","author":"RM Battleday","year":"2015","unstructured":"Battleday RM, Brem AK (2015) Modafinil for cognitive neuroenhancement in healthy non-sleep-deprived subjects: a systematic review. Eur Neuropsychopharmacol 25(11):1865\u20131881","journal-title":"Eur Neuropsychopharmacol"},{"issue":"3","key":"1351_CR22","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1111\/j.1365-2869.2005.00468.x","volume":"14","author":"NJ Wesensten","year":"2005","unstructured":"Wesensten NJ, Killgore WD, Balkin TJ (2005) Performance and alertness effects of caffeine, dextroamphetamine, and modafinil during sleep deprivation. J\u00a0Sleep Res 14(3):255\u2013266","journal-title":"J Sleep Res"},{"issue":"2","key":"1351_CR23","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1093\/sleep\/32.2.205","volume":"32","author":"WD Killgore","year":"2009","unstructured":"Killgore WD, Kahn-Greene ET, Grugle NL, Killgore DB, Balkin TJ (2009) Sustaining executive functions during sleep deprivation: a comparison of caffeine, dextroamphetamine, and modafinil. Sleep 32(2):205\u2013216","journal-title":"Sleep"},{"key":"1351_CR24","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.physbeh.2014.09.010","volume":"138","author":"KC Morasch","year":"2015","unstructured":"Morasch KC, Aaron CL, Moon JE, Gordon RK (2015) Physiological and neurobehavioral effects of cholinesterase inhibition in healthy adults. Physiol Behav 138:165\u2013172","journal-title":"Physiol Behav"},{"issue":"9","key":"1351_CR25","doi-asserted-by":"crossref","first-page":"e24126","DOI":"10.1371\/journal.pone.0024126","volume":"6","author":"JH Balsters","year":"2011","unstructured":"Balsters JH, O\u2019Connell RG, Martin MP, Galli A, Cassidy SM, Kilcullen SM et\u00a0al (2011) Donepezil impairs memory in healthy older subjects: behavioural, EEG and simultaneous EEG\/fMRI biomarkers. PLOS ONE 6(9):e24126","journal-title":"PLOS ONE"},{"issue":"1\u20132","key":"1351_CR26","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1055\/s-0028-1105890","volume":"134","author":"H Forstl","year":"2009","unstructured":"Forstl H, Bickel H, Frolich L, Gertz HJ, Gutzmann H, Horr R et al (2009) MCI-plus: mild cognitive impairment with rapid progression. Part I: prevention and therapy. Dtsch Med Wochenschr 134(1\u20132):39\u201344","journal-title":"Dtsch Med Wochenschr"},{"issue":"6","key":"1351_CR27","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1002\/hup.1044","volume":"24","author":"AL Zaninotto","year":"2009","unstructured":"Zaninotto AL, Bueno OF, Pradella-Hallinan M, Tufik S, Rusted J, Stough C et al (2009) Acute cognitive effects of donepezil in young, healthy volunteers. Hum Psychopharmacol 24(6):453\u2013464","journal-title":"Hum Psychopharmacol"},{"issue":"11","key":"1351_CR28","doi-asserted-by":"crossref","first-page":"3616","DOI":"10.1002\/hbm.20789","volume":"30","author":"H Wageningen van","year":"2009","unstructured":"van Wageningen H, Jorgensen HA, Specht K, Eichele T, Hugdahl K (2009) The effects of the glutamate antagonist memantine on brain activation to an auditory perception task. Hum Brain Mapp 30(11):3616\u20133624","journal-title":"Hum Brain Mapp"},{"key":"1351_CR29","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.neulet.2016.07.061","volume":"630","author":"K Kakefuda","year":"2016","unstructured":"Kakefuda K, Ishisaka M, Tsuruma K, Shimazawa M, Hara H (2016) Memantine, an NMDA receptor antagonist, improves working memory deficits in DGKbeta knockout mice. Neurosci Lett 630:228\u2013232","journal-title":"Neurosci Lett"},{"issue":"3","key":"1351_CR30","first-page":"327","volume":"2","author":"A Baskys","year":"2007","unstructured":"Baskys A, Hou AC (2007) Vascular dementia: pharmacological treatment approaches and perspectives. Clin Interv Aging 2(3):327\u2013335","journal-title":"Clin Interv Aging"},{"issue":"Suppl A","key":"1351_CR31","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1358\/dot.2012.48(Suppl.A).1739716","volume":"48","author":"E Masliah","year":"2012","unstructured":"Masliah E, Diez-Tejedor E (2012) The pharmacology of neurotrophic treatment with Cerebrolysin: brain protection and repair to counteract pathologies of acute and chronic neurological disorders. Drugs Today 48(Suppl A):3\u201324","journal-title":"Drugs Today"},{"key":"1351_CR32","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD009286.pub2.","author":"GE Mead","year":"2012","unstructured":"Mead GE, Hsieh CF, Lee R, Kutlubaev MA, Claxton A, Hankey GJ et\u00a0al (2012) Selective serotonin reuptake inhibitors (SSRIs) for stroke recovery. Cochrane Database Syst Rev. https:\/\/doi.org\/10.1002\/14651858.CD009286.pub2","journal-title":"Cochrane Database Syst Rev"},{"issue":"1","key":"1351_CR33","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1097\/JCP.0b013e31802e0002","volume":"27","author":"A Mowla","year":"2007","unstructured":"Mowla A, Mosavinasab M, Pani A (2007) Does fluoxetine have any effect on the cognition of patients with mild cognitive impairment? A double-blind, placebo-controlled, clinical trial. J\u00a0Clin Psychopharmacol 27(1):67\u201370","journal-title":"J Clin Psychopharmacol"},{"issue":"19","key":"1351_CR34","doi-asserted-by":"crossref","first-page":"2314","DOI":"10.1016\/j.cub.2014.08.024","volume":"24","author":"A Schaefer","year":"2014","unstructured":"Schaefer A, Burmann I, Regenthal R, Arelin K, Barth C, Pampel A et\u00a0al (2014) Serotonergic modulation of intrinsic functional connectivity. Curr Biol 24(19):2314\u20132318","journal-title":"Curr Biol"},{"issue":"12 Pt A","key":"1351_CR35","doi-asserted-by":"crossref","first-page":"2427","DOI":"10.1016\/j.bbadis.2014.09.013","volume":"1842","author":"A Grimm","year":"2014","unstructured":"Grimm A, Schmitt K, Lang UE, Mensah-Nyagan AG, Eckert A (2014) Improvement of neuronal bioenergetics by neurosteroids: implications for age-related neurodegenerative disorders. Biochim Biophys Acta 1842(12 Pt A):2427\u20132438","journal-title":"Biochim Biophys Acta"},{"key":"1351_CR36","doi-asserted-by":"crossref","first-page":"8466","DOI":"10.1038\/ncomms9466","volume":"6","author":"J Marschallinger","year":"2015","unstructured":"Marschallinger J, Schaffner I, Klein B, Gelfert R, Rivera FJ, Illes S et al (2015) Structural and functional rejuvenation of the aged brain by an approved anti-asthmatic drug. Nat Commun 6:8466","journal-title":"Nat Commun"},{"issue":"1","key":"1351_CR37","doi-asserted-by":"crossref","first-page":"178","DOI":"10.4161\/auto.26918","volume":"10","author":"SJ Sigrist","year":"2014","unstructured":"Sigrist SJ, Carmona-Gutierrez D, Gupta VK, Bhukel A, Mertel S, Eisenberg T et al (2014) Spermidine-triggered autophagy ameliorates memory during aging. Autophagy 10(1):178\u2013179","journal-title":"Autophagy"},{"issue":"24","key":"1351_CR38","doi-asserted-by":"crossref","first-page":"3903","DOI":"10.4161\/15384101.2014.973309","volume":"13","author":"S Buttner","year":"2014","unstructured":"Buttner S, Broeskamp F, Sommer C, Markaki M, Habernig L, Alavian-Ghavanini A et al (2014) Spermidine protects against alpha-synuclein neurotoxicity. Cell Cycle 13(24):3903\u20133908","journal-title":"Cell Cycle"},{"key":"1351_CR39","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1007\/978-3-319-16522-6_14","volume":"228","author":"AM Kelly","year":"2015","unstructured":"Kelly AM (2015) Non-pharmacological approaches to cognitive enhancement. Handb Exp Pharmacol 228:417\u2013439","journal-title":"Handb Exp Pharmacol"}],"container-title":["Zeitschrift f\u00fcr Gerontologie und Geriatrie"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00391-017-1351-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00391-017-1351-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00391-017-1351-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,29]],"date-time":"2023-08-29T17:39:38Z","timestamp":1693330778000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00391-017-1351-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,12,5]]},"references-count":39,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2018,2]]}},"alternative-id":["1351"],"URL":"https:\/\/doi.org\/10.1007\/s00391-017-1351-y","relation":{},"ISSN":["0948-6704","1435-1269"],"issn-type":[{"type":"print","value":"0948-6704"},{"type":"electronic","value":"1435-1269"}],"subject":[],"published":{"date-parts":[[2017,12,5]]}}}