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Das periphere Nervensystem (PNS) vermittelt zwischen Umgebung und ZNS. Mit zunehmendem Alter ver\u00e4ndert sich das PNS, was zu einer Abschw\u00e4chung von Muskeleigenreflexen und Propriozeption f\u00fchrt. Davon abzugrenzen sind Polyneuropathien (PNP) als Erkrankungen des PNS. Die Ursachen sind vielf\u00e4ltig: Neben isolierten metabolischen, immunmediierten, heredit\u00e4ren, toxischen und infekti\u00f6sen \u00c4tiologien k\u00f6nnen PNP auch Ausdruck von Systemerkrankungen sein. Neuropathien in Zusammenhang mit Diabetes, monoklonalen Gammopathien und Malignomen sind im Alter h\u00e4ufiger, auch der Anteil der kryptogenen Neuropathie nimmt im Alter zu. PNP tragen zu einer Beeintr\u00e4chtigung der Mobilit\u00e4t und erh\u00f6htem Sturzrisiko bei, was die Abkl\u00e4rung funktioneller F\u00e4higkeiten erforderlich macht. Schmerzen und sensorische St\u00f6rungen wirken sich negativ auf die Aktivit\u00e4ten des t\u00e4glichen Lebens aus. Als Folge wird die Kommunikation mit den Lebensumwelten beeintr\u00e4chtigt. Ein geriatrischer Ansatz erm\u00f6glicht neben einer exakten Diagnose auch eine umfassende, auf die individuellen Bed\u00fcrfnisse zugeschnittene Therapie.<\/jats:p>","DOI":"10.1007\/s00391-026-02593-y","type":"journal-article","created":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T08:31:05Z","timestamp":1779093065000},"page":"370-376","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Nervensystem und Kommunikation: Polyneuropathie und die Rolle des peripheren Nervensystems","The nervous system and communication: polyneuropathy and the role of the peripheral nervous system"],"prefix":"10.1007","volume":"59","author":[{"given":"Bernhard","family":"Iglseder","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,5,18]]},"reference":[{"issue":"4","key":"2593_CR1","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1001\/archneur.59.4.533","volume":"59","author":"AFJE Vrancken","year":"2002","unstructured":"Vrancken\u00a0AFJE, Franssen\u00a0H, Wokke\u00a0JHJ, Teunissen\u00a0LL, Notermans\u00a0NC (2002) Chronic idiopathic axonal polyneuropathy and successful aging of the peripheral nervous system in elderly people. 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