{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T07:53:53Z","timestamp":1793174033760,"version":"4.5.0"},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2014,8,21]],"date-time":"2014-08-21T00:00:00Z","timestamp":1408579200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Res Cardiol"],"published-print":{"date-parts":[[2015,1]]},"DOI":"10.1007\/s00392-014-0756-5","type":"journal-article","created":{"date-parts":[[2014,8,20]],"date-time":"2014-08-20T14:24:44Z","timestamp":1408544684000},"page":"51-58","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Acute coronary syndromes in octogenarians referred for invasive evaluation: treatment profile and outcomes"],"prefix":"10.1007","volume":"104","author":[{"given":"Milosz","family":"Jaguszewski","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jelena-R.","family":"Ghadri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johanna","family":"Diekmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roxana D.","family":"Bataiosu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jens P.","family":"Hellermann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annahita","family":"Sarcon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asim","family":"Siddique","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lukas","family":"Baumann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara E.","family":"St\u00e4hli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas F.","family":"L\u00fcscher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Willibald","family":"Maier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Templin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2014,8,21]]},"reference":[{"key":"756_CR1","doi-asserted-by":"crossref","first-page":"e17","DOI":"10.1161\/CIRCOUTCOMES.112.966531","volume":"5","author":"A Gupta","year":"2012","unstructured":"Gupta A, Mody P, Bikdeli B, Lampropulos JF, Dharmarajan K (2012) Most important outcomes research papers in cardiovascular disease in the elderly. Circ Cardiovasc Qual Outcomes 5:e17\u2013e26","journal-title":"Circ Cardiovasc Qual Outcomes"},{"key":"756_CR2","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1093\/ije\/31.4.776","volume":"31","author":"JM Wiener","year":"2002","unstructured":"Wiener JM, Tilly J (2002) Population ageing in the United States of America: implications for public programmes. Int J Epidemiol 31:776\u2013781","journal-title":"Int J Epidemiol"},{"key":"756_CR3","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.ahj.2004.06.003","volume":"149","author":"A Avezum","year":"2005","unstructured":"Avezum A, Makdisse M, Spencer F, Gore JM, Fox KA, Montalescot G, Eagle KA, White K, Mehta RH, Knobel E, Collet JP, Investigators G (2005) Impact of age on management and outcome of acute coronary syndrome: observations from the global registry of acute coronary events (GRACE). Am Heart J 149:67\u201373","journal-title":"Am Heart J"},{"key":"756_CR4","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1001\/jama.286.6.708","volume":"286","author":"PY Lee","year":"2001","unstructured":"Lee PY, Alexander KP, Hammill BG, Pasquali SK, Peterson ED (2001) Representation of elderly persons and women in published randomized trials of acute coronary syndromes. JAMA 286:708\u2013713","journal-title":"JAMA"},{"key":"756_CR5","doi-asserted-by":"crossref","first-page":"2549","DOI":"10.1161\/CIRCULATIONAHA.107.182615","volume":"115","author":"KP Alexander","year":"2007","unstructured":"Alexander KP, Newby LK, Cannon CP, Armstrong PW, Gibler WB, Rich MW, Van de Werf F, White HD, Weaver WD, Naylor MD, Gore JM, Krumholz HM, Ohman EM (2007) Acute coronary care in the elderly, part I: non-ST-segment-elevation acute coronary syndromes: a scientific statement for healthcare professionals from the American heart association council on clinical cardiology: in collaboration with the society of geriatric cardiology. Circulation 115:2549\u20132569","journal-title":"Circulation"},{"key":"756_CR6","doi-asserted-by":"crossref","first-page":"2570","DOI":"10.1161\/CIRCULATIONAHA.107.182616","volume":"115","author":"KP Alexander","year":"2007","unstructured":"Alexander KP, Newby LK, Armstrong PW, Cannon CP, Gibler WB, Rich MW, Van de Werf F, White HD, Weaver WD, Naylor MD, Gore JM, Krumholz HM, Ohman EM (2007) Acute coronary care in the elderly, part II: sT-segment-elevation myocardial infarction: a scientific statement for healthcare professionals from the American heart association council on clinical cardiology: in collaboration with the society of geriatric cardiology. Circulation 115:2570\u20132589","journal-title":"Circulation"},{"key":"756_CR7","doi-asserted-by":"crossref","first-page":"2501","DOI":"10.1093\/eurheartj\/ehq172","volume":"31","author":"W Wijns","year":"2010","unstructured":"Task Force on Myocardial Revascularization of the European Society of C, the European Association for Cardio-Thoracic S, European Association for Percutaneous Cardiovascular I, Wijns W, Kolh P, Danchin N, Di Mario C, Falk V, Folliguet T, Garg S, Huber K, James S, Knuuti J, Lopez-Sendon J, Marco J, Menicanti L, Ostojic M, Piepoli MF, Pirlet C, Pomar JL, Reifart N, Ribichini FL, Schalij MJ, Sergeant P, Serruys PW, Silber S, Sousa Uva M, Taggart D (2010) Guidelines on myocardial revascularization. European heart journal 31:2501\u20132555","journal-title":"European heart journal"},{"key":"756_CR8","first-page":"314","volume":"140","author":"D Radovanovic","year":"2010","unstructured":"Radovanovic D, Urban P, Simon R, Schmidli M, Maggiorini M, Rickli H, Stauffer JC, Seifert B, Gutzwiller F, Erne P, Investigators AP (2010) Outcome of patients with acute coronary syndrome in hospitals of different sizes. A report from the AMIS plus registry. Swiss Med Week 140:314\u2013322","journal-title":"Swiss Med Week"},{"key":"756_CR9","doi-asserted-by":"crossref","first-page":"2023","DOI":"10.1016\/S0735-1097(98)00466-5","volume":"32","author":"KP Alexander","year":"1998","unstructured":"Alexander KP, Peterson ED, Granger CB, Casas AC, Van de Werf F, Armstrong PW, Guerci A, Topol EJ, Califf RM (1998) Potential impact of evidence-based medicine in acute coronary syndromes: insights from GUSTO-IIb. Global Use of Strategies to open occluded arteries in acute coronary syndromes trial. J Am Coll Cardiol. 32:2023\u20132030","journal-title":"J Am Coll Cardiol."},{"key":"756_CR10","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1007\/s00392-013-0600-3","volume":"102","author":"EH Vandecasteele","year":"2013","unstructured":"Vandecasteele EH, De Buyzere M, Gevaert S, de Meester A, Convens C, Dubois P, Boland J, Sinnaeve P, De Raedt H, Vranckx P, Coussement P, Evrard P, Beauloye C, Renard M, Claeys MJ (2013) Reperfusion therapy and mortality in octogenarian STEMI patients: results from the Belgian STEMI registry. Clin Res Cardiol 102:837\u2013845 official journal of the German Cardiac Society","journal-title":"Clin Res Cardiol"},{"key":"756_CR11","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1038\/nrcardio.2012.122","volume":"9","author":"K Thygesen","year":"2012","unstructured":"Thygesen K, Alpert JS, Jaffe AS, Simoons ML, Chaitman BR, White HD (2012) Third universal definition of myocardial infarction. Nat Rev Cardiol 9:620\u2013633","journal-title":"Nat Rev Cardiol"},{"issue":"33","key":"756_CR12","first-page":"1635","volume":"2012","author":"J Perk","year":"2012","unstructured":"Perk J, De Backer G, Gohlke H, Graham I, Reiner Z, Verschuren M, Albus C, Benlian P, Boysen G, Cifkova R, Deaton C, Ebrahim S, Fisher M, Germano G, Hobbs R, Hoes A, Karadeniz S, Mezzani A, Prescott E, Ryden L, Scherer M, Syvanne M, Scholte op Reimer WJ, Vrints C, Wood D, Zamorano JL, Zannad F (2012) European guidelines on cardiovascular disease prevention in clinical practice (version, 2012) the fifth joint task force of the European society of cardiology and Other societies on cardiovascular disease prevention in clinical practice (constituted by representatives of nine societies and by invited experts). Eur Heart J 2012(33):1635\u20131701","journal-title":"Eur Heart J"},{"key":"756_CR13","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1056\/NEJMoa1208410","volume":"367","author":"H Thiele","year":"2012","unstructured":"Thiele H, Zeymer U, Neumann FJ, Ferenc M, Olbrich HG, Hausleiter J, Richardt G, Hennersdorf M, Empen K, Fuernau G, Desch S, Eitel I, Hambrecht R, Fuhrmann J, Bohm M, Ebelt H, Schneider S, Schuler G, Werdan K (2012) Intraaortic balloon support for myocardial infarction with cardiogenic shock. N Engl J Med 367:1287\u20131296","journal-title":"N Engl J Med"},{"key":"756_CR14","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1007\/s00392-013-0552-7","volume":"102","author":"U Theidel","year":"2013","unstructured":"Theidel U, Asseburg C, Giannitsis E, Katus H (2013) Cost-effectiveness of ticagrelor versus clopidogrel for the prevention of atherothrombotic events in adult patients with acute coronary syndrome in Germany. Clin Res Cardiol 102:447\u2013458 (official journal of the German Cardiac Society)","journal-title":"Clin Res Cardiol"},{"key":"756_CR15","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1093\/eurheartj\/ehi774","volume":"27","author":"A Rosengren","year":"2006","unstructured":"Rosengren A, Wallentin L, Simoons M, Gitt AK, Behar S, Battler A, Hasdai D (2006) Age, clinical presentation, and outcome of acute coronary syndromes in the Euroheart acute coronary syndrome survey. Eur Heart J 27:789\u2013795","journal-title":"Eur Heart J"},{"key":"756_CR16","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1002\/clc.4960231109","volume":"23","author":"KK Haase","year":"2000","unstructured":"Haase KK, Schiele R, Wagner S, Fischer F, Burczyk U, Zahn R, Schuster S, Senges J (2000) In-hospital mortality of elderly patients with acute myocardial infarction: data from the MITRA (maximal individual therapy in acute myocardial infarction) registry. Clin Cardiol 23:831\u2013836","journal-title":"Clin Cardiol"},{"key":"756_CR17","doi-asserted-by":"crossref","first-page":"2435","DOI":"10.1016\/j.jacc.2010.03.007","volume":"55","author":"KA Fox","year":"2010","unstructured":"Fox KA, Clayton TC, Damman P, Pocock SJ, de Winter RJ, Tijssen JG, Lagerqvist B, Wallentin L (2010) Long-term outcome of a routine versus selective invasive strategy in patients with non-ST-segment elevation acute coronary syndrome a meta-analysis of individual patient data. J Am Coll Cardiol 55:2435\u20132445","journal-title":"J Am Coll Cardiol"},{"key":"756_CR18","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1016\/S0735-1097(01)01432-2","volume":"38","author":"RH Mehta","year":"2001","unstructured":"Mehta RH, Rathore SS, Radford MJ, Wang Y, Krumholz HM (2001) Acute myocardial infarction in the elderly: differences by age. J Am Coll Cardiol 38:736\u2013741","journal-title":"J Am Coll Cardiol"},{"key":"756_CR19","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1111\/j.1532-5415.1986.tb04221.x","volume":"34","author":"AJ Bayer","year":"1986","unstructured":"Bayer AJ, Chadha JS, Farag RR, Pathy MS (1986) Changing presentation of myocardial infarction with increasing old age. J Am Geriatr Soc 34:263\u2013266","journal-title":"J Am Geriatr Soc"},{"key":"756_CR20","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1016\/S0002-9149(02)02186-0","volume":"89","author":"RJ Goldberg","year":"2002","unstructured":"Goldberg RJ, Steg PG, Sadiq I, Granger CB, Jackson EA, Budaj A, Brieger D, Avezum A, Goodman S (2002) Extent of, and factors associated with, delay to hospital presentation in patients with acute coronary disease (the GRACE registry). Am J Cardiol 89:791\u2013796","journal-title":"Am J Cardiol"},{"key":"756_CR21","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1093\/eurheartj\/ehn124","volume":"29","author":"G Devlin","year":"2008","unstructured":"Devlin G, Gore JM, Elliott J, Wijesinghe N, Eagle KA, Avezum A, Huang W, Brieger D (2008) Management and 6-month outcomes in elderly and very elderly patients with high-risk non-ST-elevation acute coronary syndromes: the global registry of acute coronary events. Eur Heart J 29:1275\u20131282","journal-title":"Eur Heart J"},{"key":"756_CR22","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1016\/j.ahj.2005.03.039","volume":"151","author":"RT Yan","year":"2006","unstructured":"Yan RT, Yan AT, Tan M, Chow CM, Fitchett DH, Ervin FL, Cha JY, Langer A, Goodman SG (2006) Age-related differences in the management and outcome of patients with acute coronary syndromes. Am Heart J 151:352\u2013359","journal-title":"Am Heart J"},{"key":"756_CR23","doi-asserted-by":"crossref","first-page":"1530","DOI":"10.1016\/j.amjcard.2009.01.369","volume":"103","author":"AJ Bagnall","year":"2009","unstructured":"Bagnall AJ, Goodman SG, Fox KA, Yan RT, Gore JM, Cheema AN, Huynh T, Chauret D, Fitchett DH, Langer A, Yan AT (2009) Influence of age on use of cardiac catheterization and associated outcomes in patients with non-ST-elevation acute coronary syndromes. Am J Cardiol 103:1530\u20131536","journal-title":"Am J Cardiol"},{"key":"756_CR24","doi-asserted-by":"crossref","first-page":"186","DOI":"10.7326\/0003-4819-141-3-200408030-00007","volume":"141","author":"RG Bach","year":"2004","unstructured":"Bach RG, Cannon CP, Weintraub WS, DiBattiste PM, Demopoulos LA, Anderson HV, DeLucca PT, Mahoney EM, Murphy SA, Braunwald E (2004) The effect of routine, early invasive management on outcome for elderly patients with non-ST-segment elevation acute coronary syndromes. Ann Intern Med 141:186\u2013195","journal-title":"Ann Intern Med"},{"key":"756_CR25","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1093\/oxfordjournals.aje.a116179","volume":"134","author":"JH Gurwitz","year":"1991","unstructured":"Gurwitz JH, Osganian V, Goldberg RJ, Chen ZY, Gore JM, Alpert JS (1991) Diagnostic testing in acute myocardial infarction: does patient age influence utilization patterns? The worcester heart attack study. Am J Epidemiol 134:948\u2013957","journal-title":"Am J Epidemiol"},{"key":"756_CR26","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1161\/CIRCOUTCOMES.109.858456","volume":"3","author":"DT Ko","year":"2010","unstructured":"Ko DT, Ross JS, Wang Y, Krumholz HM (2010) Determinants of cardiac catheterization use in older Medicare patients with acute myocardial infarction. Circ Cardiovasc Qual Outcomes 3:54\u201362","journal-title":"Circ Cardiovasc Qual Outcomes"},{"key":"756_CR27","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.4244\/EIJV7I10A191","volume":"7","author":"H Rittger","year":"2012","unstructured":"Rittger H, Hochadel M, Behrens S, Hauptmann KE, Zahn R, Mudra H, Brachmann J, Senges J, Zeymer U (2012) Age-related differences in diagnosis, treatment and outcome of acute coronary syndromes: results from the German ALKK registry. EuroIntervention 7:1197\u20131205","journal-title":"EuroIntervention"},{"key":"756_CR28","doi-asserted-by":"crossref","first-page":"115","DOI":"10.4414\/cvm.2013.00156","volume":"16","author":"JRJM Ghadri","year":"2013","unstructured":"Ghadri JRJM, Sacron A, Srikantharupan S, Pfister P, Siddique A, Kaufmann PA, Wyss CA, Gaemperli O, Landmesser U, Altwegg L, Maier W, Corti R, L\u00fcscher TF, Templin C (2013) Current outcome of acute coronary syndromes: data from the zurich-acute coronary syndrome (Z-ACS) registry. Cardiovasc Med 16:115\u2013122","journal-title":"Cardiovasc Med"},{"key":"756_CR29","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1001\/jama.2012.10065","volume":"308","author":"L Raber","year":"2012","unstructured":"Raber L, Kelbaek H, Ostojic M, Baumbach A, Heg D, Tuller D, von Birgelen C, Roffi M, Moschovitis A, Khattab AA, Wenaweser P, Bonvini R, Pedrazzini G, Kornowski R, Weber K, Trelle S, Luscher TF, Taniwaki M, Matter CM, Meier B, Juni P, Windecker S (2012) Effect of biolimus-eluting stents with biodegradable polymer vs bare-metal stents on cardiovascular events among patients with acute myocardial infarction: the COMFORTABLE AMI randomized trial. JAMA 308:777\u2013787","journal-title":"JAMA"},{"key":"756_CR30","doi-asserted-by":"crossref","first-page":"807","DOI":"10.2459\/JCM.0b013e3283609350","volume":"14","author":"M Fiechter","year":"2013","unstructured":"Fiechter M, Ghadri JR, Jaguszewski M, Siddique A, Vogt S, Haller RB, Halioua R, Handzic A, Kaufmann PA, Corti R, Luscher TF, Templin C (2013) Impact of inflammation on adverse cardiovascular events in patients with acute coronary syndromes. J Cardiovasc Med 14:807\u2013814 (Hagerstown)","journal-title":"J Cardiovasc Med"},{"key":"756_CR31","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1016\/S0002-9149(99)80619-5","volume":"75","author":"W Devlin","year":"1995","unstructured":"Devlin W, Cragg D, Jacks M, Friedman H, O\u2019Neill W, Grines C (1995) Comparison of outcome in patients with acute myocardial infarction aged >75\u00a0years with that in younger patients. Am J Cardiol 75:573\u2013576","journal-title":"Am J Cardiol"}],"container-title":["Clinical Research in Cardiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00392-014-0756-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00392-014-0756-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00392-014-0756-5","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,14]],"date-time":"2019-08-14T04:26:30Z","timestamp":1565756790000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00392-014-0756-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,8,21]]},"references-count":31,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2015,1]]}},"alternative-id":["756"],"URL":"https:\/\/doi.org\/10.1007\/s00392-014-0756-5","relation":{},"ISSN":["1861-0684","1861-0692"],"issn-type":[{"value":"1861-0684","type":"print"},{"value":"1861-0692","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,8,21]]}}}