{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T07:05:21Z","timestamp":1782457521699,"version":"3.54.5"},"reference-count":46,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2019,7,19]],"date-time":"2019-07-19T00:00:00Z","timestamp":1563494400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2019,7,19]],"date-time":"2019-07-19T00:00:00Z","timestamp":1563494400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/100004337","name":"Roche","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004337","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Res Cardiol"],"published-print":{"date-parts":[[2020,4]]},"DOI":"10.1007\/s00392-019-01529-4","type":"journal-article","created":{"date-parts":[[2019,7,19]],"date-time":"2019-07-19T13:02:59Z","timestamp":1563541379000},"page":"476-487","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Management and outcomes of patients with unstable angina with undetectable, normal, or intermediate hsTnT levels"],"prefix":"10.1007","volume":"109","author":[{"given":"Evangelos","family":"Giannitsis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moritz","family":"Biener","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hauke","family":"Hund","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Mueller-Hennessen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehrshad","family":"Vafaie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jochen","family":"Gandowitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph","family":"Riedle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia","family":"L\u00f6hr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hugo A.","family":"Katus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiril M.","family":"Stoyanov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,7,19]]},"reference":[{"key":"1529_CR1","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1373\/clinchem.2009.132654","volume":"56","author":"E Giannitsis","year":"2010","unstructured":"Giannitsis E, Kurz K, Hallermayer K, Jarausch J, Jaffe AS, Katus HA (2010) Analytical validation of a high-sensitivity cardiac troponin T assay. Clin Chem 56:254\u2013261","journal-title":"Clin Chem"},{"key":"1529_CR2","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1056\/NEJMoa0903515","volume":"361","author":"T Keller","year":"2009","unstructured":"Keller T, Zeller T, Peetz D et al (2009) Sensitive troponin I assay in early diagnosis of acute myocardial infarction. N Engl J Med 361:868\u2013877","journal-title":"N Engl J Med"},{"key":"1529_CR3","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1056\/NEJMoa0900428","volume":"361","author":"T Reichlin","year":"2009","unstructured":"Reichlin T, Hochholzer W, Bassetti S (2009) Early diagnosis of myocardial infarction with sensitive cardiac troponin assays. N Engl J Med 361:858\u2013867","journal-title":"N Engl J Med"},{"key":"1529_CR4","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1177\/2048872616658591","volume":"7","author":"Y Sandoval","year":"2018","unstructured":"Sandoval Y, Apple FS, Smith SW (2018) High-sensitivity cardiac troponin assays and unstable angina. Eur Heart J Acute Cardiovasc Care 7:120\u2013128","journal-title":"Eur Heart J Acute Cardiovasc Care"},{"key":"1529_CR5","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1016\/j.amjmed.2015.01.044","volume":"128","author":"M D\u2019Souza","year":"2015","unstructured":"D\u2019Souza M, Sarkisian L, Saaby L (2015) Diagnosis of unstable angina pectoris has declined markedly with the advent of more sensitive troponin assays. Am J Med 128:852\u2013860","journal-title":"Am J Med"},{"key":"1529_CR6","doi-asserted-by":"crossref","first-page":"3324","DOI":"10.1093\/eurheartj\/ehw232","volume":"37","author":"R Twerenbold","year":"2016","unstructured":"Twerenbold R, Jaeger C, Rubini Gimenez M (2016) Impact of high sensitivity cardiac troponin on use of coronary angiography, cardiac stress testing, and time to discharge in suspected acute myocardial infarction. Eur Heart J 37:3324\u20133332","journal-title":"Eur Heart J"},{"issue":"1423\u201330","key":"1529_CR7","first-page":"e5","volume":"130","author":"KM Eggers","year":"2017","unstructured":"Eggers KM, Jernberg T, Lindahl B (2017) Unstable angina in the era of cardiac troponin assays with improved sensitivity\u2014a clinical dilemma. Am J Med 130(1423\u201330):e5","journal-title":"Am J Med"},{"key":"1529_CR8","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1177\/2048872616641901","volume":"6","author":"E Giannitsis","year":"2017","unstructured":"Giannitsis E, Wallentin L, James SK et al (2017) Outcomes after planned invasive or conservative treatment strategy in patients with non-ST-elevation acute coronary syndrome and a normal value of high sensitivity troponin at randomisation: a Platelet Inhibition and Patient Outcomes (PLATO) trial biomarker substudy. Eur Heart J Acute Cardiovasc Care 6:500\u2013510","journal-title":"Eur Heart J Acute Cardiovasc Care"},{"key":"1529_CR9","doi-asserted-by":"crossref","first-page":"e139","DOI":"10.1016\/j.jacc.2014.09.017","volume":"64","author":"EA Amsterdam","year":"2014","unstructured":"Amsterdam EA, Wenger NK, Brindis RG, American College of Cardiology, American Heart Association Task Force on Practice Guidelines, Society for Cardiovascular Angiography and Interventions, American Association for Clinical Chemistry et al (2014) 2014 AHA\/ACC Guideline for the management of patients with non-ST-elevation acute coronary syndromes: a report of the American College of Cardiology\/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol 64:e139\u2013e228","journal-title":"J Am Coll Cardiol"},{"key":"1529_CR10","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1093\/eurheartj\/ehv320","volume":"37","author":"M Roffi","year":"2015","unstructured":"Roffi M, Patrono C, Collet JP et al (2015) 2015 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: task force for the management of acute coronary syndromes in patients presenting without persistent ST-Segment Elevation of the European Society of Cardiology (ESC). Eur Heart J 37:267\u2013315","journal-title":"Eur Heart J"},{"key":"1529_CR11","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1093\/ije\/dyq165","volume":"40","author":"S Mendis","year":"2011","unstructured":"Mendis S, Thygesen K, Kuulasmaa K et al (2011) Writing group on behalf of the participating experts of the WHO consultation for revision of WHO definition of myocardial infarction. World Health Organization definition of myocardial infarction: 2008\u20132009 revision. Int J Epidemiol 40:139\u2013146","journal-title":"Int J Epidemiol"},{"key":"1529_CR12","doi-asserted-by":"crossref","first-page":"2452","DOI":"10.1161\/CIRCULATIONAHA.113.001258","volume":"127","author":"E Braunwald","year":"2013","unstructured":"Braunwald E, Morrow DA (2013) Unstable angina: is it time for a requiem? Circulation 127:2452\u20132457","journal-title":"Circulation"},{"key":"1529_CR13","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.clinbiochem.2014.08.021","volume":"48","author":"FS Apple","year":"2015","unstructured":"Apple FS, Jaffe AS, Collinson P et al (2015) IFCC educational materials on selected analytical and clinical applications of high sensitivity cardiac troponin assays. Clin Biochem 48:201\u2013203","journal-title":"Clin Biochem"},{"key":"1529_CR14","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1136\/hrt.2010.193201","volume":"97","author":"G Korosoglou","year":"2011","unstructured":"Korosoglou G, Lehrke S, Mueller D et al (2011) Determinants of troponin release in patients with stable coronary artery disease: insights from CT angiography characteristics of atherosclerotic plaque. Heart 97:823\u2013831","journal-title":"Heart"},{"key":"1529_CR15","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S0735-1097(96)00447-0","volume":"29","author":"B Lindahl","year":"1997","unstructured":"Lindahl B, Venge P, Wallentin L (1997) Troponin T identifies patients with unstable coronary artery disease who benefit from long-term antithrombotic protection. Fragmin in Unstable Coronary Artery Disease (FRISC) Study Group. J Am Coll Cardiol 29:43\u201348","journal-title":"J Am Coll Cardiol"},{"key":"1529_CR16","doi-asserted-by":"crossref","first-page":"1812","DOI":"10.1016\/S0735-1097(00)00942-6","volume":"36","author":"DA Morrow","year":"2000","unstructured":"Morrow DA, Antman EM, Tanasijevic M et al (2000) Cardiac troponin I for stratification of early outcomes and the efficacy of enoxaparin in unstable angina: a TIMI-11B substudy. J Am Coll Cardiol 36:1812\u20131817","journal-title":"J Am Coll Cardiol"},{"issue":"Suppl A","key":"1529_CR17","doi-asserted-by":"crossref","first-page":"A14","DOI":"10.1016\/S1520-765X(01)90020-3","volume":"3","author":"CW Hamm","year":"2001","unstructured":"Hamm CW (2001) GP IIb\/IIIa receptor antagonists in unstable angina: troponin level-based patient selection. Eur Heart J Suppl 3(Suppl A):A14\u2013A20","journal-title":"Eur Heart J Suppl"},{"key":"1529_CR18","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1373\/clinchem.2016.264788","volume":"63","author":"A Eisen","year":"2017","unstructured":"Eisen A, Bonaca MP, Jarolim P et al (2017) High-sensitivity Troponin I in stable patients with atherosclerotic disease in the TRA 2\u00b0P\u2014TIMI 50 Trial. Clin Chem 63:307\u2013315","journal-title":"Clin Chem"},{"key":"1529_CR19","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1161\/CIRCULATIONAHA.113.004420","volume":"129","author":"L Wallentin","year":"2014","unstructured":"Wallentin L, Lindholm D, Siegbahn A et al (2014) Biomarkers in relation to the effects of ticagrelor in comparison with clopidogrel in non-ST-elevation acute coronary syndrome patients managed with or without in-hospital revascularization: a substudy from the Prospective Randomized Platelet Inhibition and Patient Outcomes (PLATO) trial. Circulation 129:293\u2013303","journal-title":"Circulation"},{"issue":"5","key":"1529_CR20","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1067\/mhj.2002.121733","volume":"143","author":"E Diderholm","year":"2002","unstructured":"Diderholm E, Andr\u00e9n B, Frostfeldt G, Fast Revascularisation during InStability in Coronary artery disease (FRISC II) Investigators et al (2002) The prognostic and therapeutic implications of increased troponin T levels and ST depression in unstable coronary artery disease: the FRISC II invasive troponin T electrocardiogram substudy. Am Heart J 143(5):760\u2013767","journal-title":"Am Heart J"},{"key":"1529_CR21","doi-asserted-by":"crossref","first-page":"1531","DOI":"10.1001\/jama.295.13.joc60034","volume":"295","author":"A Kastrati","year":"2006","unstructured":"Kastrati A, Mehilli J, Neumann FJ, Intracoronary Stenting and Antithrombotic: Regimen Rapid Early Action for Coronary Treatment 2 (ISAR-REACT 2) Trial Investigators, Intracoronary Stenting and Antithrombotic Regimen: Rapid Early Action for Coronary Treatment 2 (ISAR-REACT 2) Trial Investigators et al (2006) Abciximab in patients with acute coronary syndromes undergoing percutaneous coronary intervention after clopidogrel pretreatment: the ISAR-REACT 2 randomized trial. JAMA 295:1531\u20131538","journal-title":"JAMA"},{"key":"1529_CR22","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.1056\/NEJMoa044259","volume":"353","author":"RJ de Winter","year":"2005","unstructured":"de Winter RJ, Windhausen F, Cornel JH, Invasive versus Conservative Treatment in Unstable Coronary Syndromes (ICTUS) Investigators et al (2005) Early invasive versus selectively invasive management for acute coronary syndromes. N Engl J Med 353:1095\u20131104","journal-title":"N Engl J Med"},{"key":"1529_CR23","doi-asserted-by":"crossref","first-page":"1146","DOI":"10.1016\/j.jacc.2006.05.056","volume":"48","author":"SK James","year":"2006","unstructured":"James SK, Lindb\u00e4ck J, Tilly J et al (2006) Troponin-T and N-terminal pro-B-type natriuretic peptide predict mortality benefit from coronary revascularization in acute coronary syndromes: a GUSTO-IV substudy. J Am Coll Cardiol 48:1146\u20131154","journal-title":"J Am Coll Cardiol"},{"key":"1529_CR24","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1373\/clinchem.2011.171827","volume":"58","author":"M Mueller","year":"2012","unstructured":"Mueller M, Biener M, Vafaie M et al (2012) Absolute and relative kinetic changes of high-sensitivity cardiac troponin T in acute coronary syndrome and in patients with increased troponin in the absence of acute coronary syndrome. Clin Chem 58:209\u2013218","journal-title":"Clin Chem"},{"key":"1529_CR25","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/j.ahj.2010.05.023","volume":"160","author":"B Lindahl","year":"2010","unstructured":"Lindahl B, Venge P, James S (2010) The new high-sensitivity cardiac troponin T assay improves risk assessment in acute coronary syndromes. Am Heart J 160:224\u2013229","journal-title":"Am Heart J"},{"key":"1529_CR26","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/j.ijcard.2015.10.170","volume":"203","author":"N Bandstein","year":"2016","unstructured":"Bandstein N, Ljung R, Holzmann MJ (2016) Risk of revisits to the emergency department in admitted versus discharged patients with chest pain but without myocardial infarction in relation to high-sensitivity cardiac troponin T levels. Int J Cardiol 203:341\u2013346","journal-title":"Int J Cardiol"},{"key":"1529_CR27","doi-asserted-by":"crossref","first-page":"2417","DOI":"10.1093\/eurheartj\/ehw029","volume":"37","author":"KM Eggers","year":"2016","unstructured":"Eggers KM, Lindahl B, Melki D, Jernberg T (2016) Consequences of implementing a cardiac troponin assay with improved sensitivity at Swedish coronary care units: an analysis from the SWEDEHEART registry. Eur Heart J 37:2417\u20132424","journal-title":"Eur Heart J"},{"key":"1529_CR28","doi-asserted-by":"crossref","first-page":"1591","DOI":"10.1136\/heartjnl-2013-305440","volume":"100","author":"J Sanchis","year":"2014","unstructured":"Sanchis J, Garc\u00eda-Blas S, Mainar L et al (2014) High-sensitivity versus conventional troponin for management and prognosis assessment of patients with acute chest pain. Heart 100:1591\u20131596","journal-title":"Heart"},{"key":"1529_CR29","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1056\/NEJMoa0904327","volume":"361","author":"L Wallentin","year":"2009","unstructured":"Wallentin L, Becker RC, Budaj A et al (2009) Ticagrelor versus clopidogrel in patients with acute coronary syndromes. N Engl J Med 361:1045\u20131057","journal-title":"N Engl J Med"},{"key":"1529_CR30","doi-asserted-by":"publisher","first-page":"204887261986191","DOI":"10.1177\/2048872619861911","volume":"12","author":"KM Stoyanov","year":"2019","unstructured":"Stoyanov KM, Hund H, Biener M et al (2019) RAPID-CPU: a prospective study on implementation of the ESC o\/1-hour algorithm and safety of discharge after rule-out of myocardial i8nfarction. Eur Heart J Acute Cardiovasc Care. 12:2048872619861911. https:\/\/doi.org\/10.1177\/2048872619861911","journal-title":"Eur Heart J Acute Cardiovasc Care."},{"key":"1529_CR31","doi-asserted-by":"crossref","first-page":"2551","DOI":"10.1093\/eurheartj\/ehs184","volume":"33","author":"K Thygesen","year":"2012","unstructured":"Thygesen K, Alpert JS, Jaffe AS et al (2012) Third universal definition of myocardial infarction. Eur Heart J 33:2551\u20132567","journal-title":"Eur Heart J"},{"issue":"3","key":"1529_CR32","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1093\/eurheartj\/ehy462","volume":"40","author":"K Thygesen","year":"2019","unstructured":"Thygesen K, Alpert JS, Jaffe AS et al (2019) Fourth universal definition of myocardial infarction (2018). Eur Heart J 40(3):237\u2013269","journal-title":"Eur Heart J"},{"key":"1529_CR33","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1136\/bmj.38985.646481.55","volume":"333","author":"KA Fox","year":"2006","unstructured":"Fox KA, Dabbous OH, Goldberg RJ et al (2006) Prediction of risk of death and myocardial infarction in the six months after presentation with acute coronary syndrome: prospective multinational observational study (GRACE). BMJ 333:1091","journal-title":"BMJ"},{"key":"1529_CR34","doi-asserted-by":"crossref","first-page":"2999","DOI":"10.1093\/eurheartj\/ehr236","volume":"32","author":"CW Hamm","year":"2011","unstructured":"Hamm CW, Bassand JP, Agewall S et al (2011) ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: the Task Force for the management of acute coronary syndromes (ACS) in patients presenting without persistent ST-segment elevation of the European Society of Cardiology (ESC). Eur Heart J 32:2999\u20133054","journal-title":"Eur Heart J"},{"key":"1529_CR35","doi-asserted-by":"crossref","first-page":"1408","DOI":"10.1161\/01.CIR.92.6.1408","volume":"92","author":"PJ de Feyter","year":"1995","unstructured":"de Feyter PJ, Ozaki Y, Baptista J et al (1995) Ischemia-related lesion characteristics in patients with stable or unstable angina. A study with intracoronary angioscopy and ultrasound. Circulation 92:1408\u20131413","journal-title":"Circulation"},{"key":"1529_CR36","doi-asserted-by":"crossref","first-page":"e001727","DOI":"10.1161\/CIRCINTERVENTIONS.114.001727","volume":"8","author":"T Lee","year":"2015","unstructured":"Lee T, Murai T, Yonetsu T et al (2015) Relationship between subclinical cardiac troponin I elevation and culprit lesion characteristics assessed by optical coherence tomography in patients undergoing elective percutaneous coronary intervention. Circ Cardiovasc Interv 8:e001727","journal-title":"Circ Cardiovasc Interv"},{"key":"1529_CR37","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1161\/01.CIR.0000109696.92474.92","volume":"109","author":"K Okamatsu","year":"2004","unstructured":"Okamatsu K, Takano M, Sakai S (2004) Elevated troponin T levels and lesion characteristics in non-ST-elevation acute coronary syndromes. Circulation 109:465\u2013470","journal-title":"Circulation"},{"key":"1529_CR38","doi-asserted-by":"crossref","first-page":"1160","DOI":"10.1161\/01.CIR.0000157141.00778.AC","volume":"111","author":"SZ Rittersma","year":"2005","unstructured":"Rittersma SZ, van der Wal AC, Koch KT et al (2005) Plaque instability frequently occurs days or weeks before occlusive coronary thrombosis: a pathological thrombectomy study in primary percutaneous coronary intervention. Circulation 111:1160\u20131165","journal-title":"Circulation"},{"key":"1529_CR39","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1097\/00019501-199309000-00001","volume":"4","author":"E Arbustini","year":"1993","unstructured":"Arbustini E, Grasso M, Diegoli M et al (1993) Coronary thrombosis in non-cardiac death. Coron Artery Dis 4:751\u2013759","journal-title":"Coron Artery Dis"},{"key":"1529_CR40","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1016\/j.jcmg.2016.09.025","volume":"10","author":"AJ Brown","year":"2017","unstructured":"Brown AJ, Shah ASV, West NEJ et al (2017) High-sensitivity Troponin I is associated with high-risk plaque and MACE in stable coronary artery disease. JACC Cardiovasc Imaging 10:1200\u20131203","journal-title":"JACC Cardiovasc Imaging"},{"key":"1529_CR41","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1038\/nrcardio.2013.129","volume":"10","author":"E Giannitsis","year":"2013","unstructured":"Giannitsis E, Katus HA (2013) Cardiac troponin level elevations not related to acute coronary syndromes. Nat Rev Cardiol 10:623\u2013634","journal-title":"Nat Rev Cardiol"},{"key":"1529_CR42","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl-2018-314305","author":"C Puelacher","year":"2019","unstructured":"Puelacher C, Gugala M, Adamson PD (2019) Incidence and outcomes of unstable angina compared with non-ST-elevation myocardial infarction. Heart. https:\/\/doi.org\/10.1136\/heartjnl-2018-314305","journal-title":"Heart"},{"key":"1529_CR43","doi-asserted-by":"crossref","first-page":"3","DOI":"10.2174\/1573403X12666160504100025","volume":"13","author":"J Engel","year":"2017","unstructured":"Engel J, Damen NL, van der Wulp I, de Bruijne MC, Wagner C (2017) Adherence to cardiac practice guidelines in the management of non-ST-elevation acute coronary syndromes: a systematic literature review. Curr Cardiol Rev. 13:3\u201327","journal-title":"Curr Cardiol Rev."},{"key":"1529_CR44","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1016\/j.amjmed.2015.04.012","volume":"128","author":"EW Carlton","year":"2015","unstructured":"Carlton EW, Than M, Cullen L, Khattab A, Greaves K (2015) \u2018Chest pain typicality\u2019 in suspected acute coronary syndromes and the impact of clinical experience. Am J Med 128:1109\u20131116","journal-title":"Am J Med"},{"key":"1529_CR45","doi-asserted-by":"crossref","first-page":"1561","DOI":"10.1016\/j.amjcard.2010.01.014","volume":"105","author":"LK Hermann","year":"2010","unstructured":"Hermann LK, Weingart SD, Yoon YM et al (2010) Comparison of frequency of inducible myocardial ischemia in patients presenting to emergency department with typical versus atypical or nonanginal chest pain. Am J Cardiol 105:1561\u20131564","journal-title":"Am J Cardiol"},{"key":"1529_CR46","doi-asserted-by":"crossref","first-page":"e000888","DOI":"10.1136\/openhrt-2018-000888","volume":"5","author":"K Fladseth","year":"2018","unstructured":"Fladseth K, Kristensen A, Mannsverk J, Trovik T, Schirmer H (2018) Pre-test characteristics of unstable angina patients with obstructive coronary artery disease confirmed by coronary angiography. Open Heart 5:e000888","journal-title":"Open Heart"}],"container-title":["Clinical Research in Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00392-019-01529-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00392-019-01529-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00392-019-01529-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,24]],"date-time":"2022-09-24T07:36:06Z","timestamp":1664004966000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00392-019-01529-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7,19]]},"references-count":46,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020,4]]}},"alternative-id":["1529"],"URL":"https:\/\/doi.org\/10.1007\/s00392-019-01529-4","relation":{},"ISSN":["1861-0684","1861-0692"],"issn-type":[{"value":"1861-0684","type":"print"},{"value":"1861-0692","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,7,19]]},"assertion":[{"value":"17 April 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 July 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 July 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"Dr. Giannitsis reports grants from Roche Diagnostics, during the conduct of the study; grants, personal fees and non-financial support from Roche Diagnostics, grants, personal fees and non-financial support from AstraZeneca, grants, personal fees and non-financial support from Bayer Vital, grants, personal fees and non-financial support from Brahms Thermo Fisher, personal fees from Daiichi Sankyo, personal fees from Boehringer Ingelheim, outside the submitted work. Dr. Biener reports grants from Roche Diagnostics, during the conduct of the study; grants and non-financial support from AstraZeneca, non-financial support from Brahms Thermo Fisher, outside the submitted work. Dr. Mueller-Hennessen reports grants from Medical Faculty of the University of Heidelberg, grants and personal fees from Roche Diagnostics, grants and non-financial support from Brahms Thermo Fisher, outside the submitted work. Dr. Vafaie reports grants from Bayer Vital, grants from Daiichi Sankyo, outside the submitted work. Dr. Katus reports personal fees from Roche Diagnostics, personal fees from AstraZeneca, personal fees from Bayer Vital, personal fees from Daiichi Sankyo, outside the submitted work. All other authors have no conflicts of interest to declare.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}