{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,18]],"date-time":"2026-07-18T06:56:40Z","timestamp":1784357800644,"version":"3.55.0"},"reference-count":40,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2020,5,16]],"date-time":"2020-05-16T00:00:00Z","timestamp":1589587200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2020,5,16]],"date-time":"2020-05-16T00:00:00Z","timestamp":1589587200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Res Cardiol"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Impact of telemedicine with remote patient monitoring (RPM) in implantable cardioverter\u2013defibrillator (ICD) patients on clinical outcomes has been investigated in various clinical settings with divergent results. However, role of RPM on patient-reported-outcomes (PRO) is unclear. The INFRARED-ICD trial aimed to investigate the effect of RPM in addition to standard-of-care on PRO in a mixed ICD patient cohort.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods and results<\/jats:title>\n                <jats:p>Patients were randomized to RPM (<jats:italic>n<\/jats:italic>\u2009=\u200992) or standard in-office-FU (<jats:italic>n<\/jats:italic>\u2009=\u200988) serving as control group (CTL). At baseline and on a monthly basis over 1 year, study participants completed the EQ-5D questionnaire for the primary outcome Quality of Life (QoL), the Hospital Anxiety and Depression Scale, and the Florida Patient Acceptance Survey questionnaire for secondary outcomes. Demographic characteristics (82% men, mean age 62.3\u00a0years) and PRO at baseline were not different between RPM and CTL. Primary outcome analysis showed that additional RPM was not superior to CTL with respect to QoL over 12\u00a0months [+\u20091.2 vs.\u2009+\u20093.9 points in CTL and RPM group, respectively (<jats:italic>p<\/jats:italic>\u2009=\u20090.24)]. Pre-specified analyses could not identify subgroups with improved QoL by the use of RPM. Neither levels of anxiety (\u2212\u00a00.4 vs. \u2212\u00a00.3, <jats:italic>p<\/jats:italic>\u2009=\u20090.88), depression (+\u20090.3 vs.\u2009\u00b1\u20090.0, <jats:italic>p<\/jats:italic>\u2009=\u20090.38), nor device acceptance (+\u20091.1 vs.\u2009+\u20091.6, <jats:italic>p<\/jats:italic>\u2009=\u20090.20) were influenced by additional use of RPM.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>The results of the present study show that PRO were not improved by RPM in addition to standard-of-care FU. Careful evaluation and planning of future trials in selected ICD patients are warranted before implementing RPM in routine practice.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Graphic abstract<\/jats:title>\n                \n              <\/jats:sec>","DOI":"10.1007\/s00392-020-01667-0","type":"journal-article","created":{"date-parts":[[2020,5,16]],"date-time":"2020-05-16T10:03:38Z","timestamp":1589623418000},"page":"789-800","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["The INFluence of Remote monitoring on Anxiety\/depRession, quality of lifE, and Device acceptance in ICD patients: a prospective, randomized, controlled, single-center trial"],"prefix":"10.1007","volume":"110","author":[{"given":"Florian","family":"Leppert","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes","family":"Siebermair","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulrich","family":"Wesemann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eimo","family":"Martens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan M.","family":"Sattler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Scholz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Veith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wolfgang","family":"Greiner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tienush","family":"Rassaf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"K\u00e4\u00e4b","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6326-1537","authenticated-orcid":false,"given":"Reza","family":"Wakili","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,5,16]]},"reference":[{"issue":"7","key":"1667_CR1","doi-asserted-by":"publisher","first-page":"1090","DOI":"10.1016\/j.jacc.2004.12.053","volume":"45","author":"W Whang","year":"2005","unstructured":"Whang W, Albert CM, Sears SF Jr et al (2005) Depression as a predictor for appropriate shocks among patients with implantable cardioverter\u2013defibrillators: results from the Triggers of Ventricular Arrhythmias (TOVA) study. 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