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However, systematic evidence on this subject is sparse. We aimed to investigate the rate of emergent hospital admissions, subsequent invasive treatments and comorbidities during the COVID-19 pandemic in Germany.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Methods and results<\/jats:title>\n<jats:p>This was a retrospective analysis of health insurance claims data from the second largest insurance fund in Germany, BARMER. Patients hospitalized for acute myocardial infarction, acute limb ischemia, aortic rupture, stroke or transient ischemic attack (TIA) between January 1, 2019, and May 31, 2020, were included. Admission rates per 100,000 insured, invasive treatments and comorbidities were compared from January\u2013May 2019 (pre-COVID) to January\u2013May 2020 (COVID). A total of 115,720 hospitalizations were included in the current analysis (51.3% females, mean age 72.9\u00a0years). Monthly admission rates declined from 78.6\/100,000 insured (pre-COVID) to 70.6\/100,000 (COVID). The lowest admission rate was observed in April 2020 (61.6\/100,000). Administration rates for ST-segment elevation myocardial infarction (7.3\u20136.6), non-ST-segment elevation myocardial infarction (16.8\u201314.6), acute limb ischemia (5.1\u20134.6), stroke (35.0\u201332.5) and TIA (13.7\u201311.9) decreased from pre-COVID to COVID. Baseline comorbidities and the percentage of these patients treated with interventional or open-surgical procedures remained similar over time across all entities. In-hospital mortality in hospitalizations for stroke increased from pre-COVID to COVID (8.5\u20139.8%).<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Conclusions<\/jats:title>\n<jats:p>Admission rates for cardiovascular and cerebrovascular emergencies declined during the pandemic in Germany, while patients\u2019 comorbidities and treatment allocations remained unchanged. Further investigation is warranted to identify underlying reasons and potential implications on patients\u2019 outcomes.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Graphic abstract<\/jats:title>\n\n<\/jats:sec>","DOI":"10.1007\/s00392-020-01723-9","type":"journal-article","created":{"date-parts":[[2020,8,4]],"date-time":"2020-08-04T15:04:53Z","timestamp":1596553493000},"page":"1540-1548","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":59,"title":["Temporal trends in the presentation of cardiovascular and cerebrovascular emergencies during the COVID-19 pandemic in Germany: an analysis of health insurance claims"],"prefix":"10.1007","volume":"109","author":[{"given":"Moritz","family":"Seiffert","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabian J.","family":"Brunner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marko","family":"Remmel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G\u00f6tz","family":"Thomalla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ursula","family":"Marschall","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helmut","family":"L\u2019Hoest","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Acar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eike S.","family":"Debus","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefan","family":"Blankenberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Gerloff","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0406-3319","authenticated-orcid":false,"given":"Christian-Alexander","family":"Behrendt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,8,4]]},"reference":[{"issue":"10223","key":"1723_CR1","doi-asserted-by":"publisher","first-page":"470","DOI":"10.1016\/S0140-6736(20)30185-9","volume":"395","author":"C Wang","year":"2020","unstructured":"Wang C, Horby PW, Hayden FG, Gao GF (2020) A novel coronavirus outbreak of global health concern. 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Dr. Brunner reports grant from the ASPIRE Cardiovascular grant award, Pfizer, outside the submitted work. Dr. Thomalla has received reports grant support and lecture fees from Bayer, personal fees from Acandis, Boehringer Ingelheim, Bristol-Myers Squibb\/Pfizer, and Daiichi Sankyo, Portola, and Stryker outside the submitted work. Dr. Gerloff reports personal fees from Amgen, Bayer Vital, Bristol-Myers Squibb, Boehringer Ingelheim, Sanofi Aventis, Abbott, and Prediction Biosciences outside the submitted work. Dr. Behrendt and Dr. Debus report grants from the German Federal Joint Committee and grants from German Stifterverband outside the submitted work. The other authors declare no conflicts of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Several review boards have determined that using anonymized data from claims or national statistics retrospectively is not human subject research because de-identified datasets were used.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"All analyses were following the European Union General Data Privacy Regulation (EU-GDPR), considering the theoretical concept of k-anonymity. Thus, patient informed consent was not obtained for this retrospective secondary data analysis [31].","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"The data will be shared on reasonable request to the corresponding author.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Availability of data and material (data transparency)"}}]}}