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The baseline surgical risk estimated by the Society of Thoracic Surgeons (STS) score declined from 7.2\u2009\u00b1\u20096.2% to 4.6\u2009\u00b1\u20093.7% (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001) as a consequence of lower comorbidity burden, whereas mean age remained unchanged (2013 81.0\u2009\u00b1\u20096.1; 2020 80.8\u2009\u00b1\u20096.4;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.976) with patients\u2009\u2265\u200980\u00a0years accounting for about two-third of the treated cohort.\n                    <\/jats:p>\n                    <jats:p>\n                      Periprocedural complications including bleeding (2013 24.5%; 2020 12.1%;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001), vascular complications (2013 20.7%; 2020 11.7%;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001) and new permanent pacemaker implantation (2013 20.1%; 2020 13.8%,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001) decreased significantly. Similarly, the 30-day mortality decreased from 5.4% to 2.1% (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001), but remained high in high-risk patients (STS\u2009&gt;\u20098% 2013 7.5%; 2020 6.9%;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.778).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>From 2013 to 2020, mortality and burden of complications following TAVI procedure significantly decreased in a large multicenter registry from Germany. Proportion of elderly patients remained stable, while the surgical risk profile decreased.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Graphical abstract<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1007\/s00392-021-01963-3","type":"journal-article","created":{"date-parts":[[2021,11,9]],"date-time":"2021-11-09T03:02:36Z","timestamp":1636426956000},"page":"881-888","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":47,"title":["Temporal trends of TAVI treatment characteristics in high volume centers in Germany 2013\u20132020"],"prefix":"10.1007","volume":"111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2678-3501","authenticated-orcid":false,"given":"Victor","family":"Mauri","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed","family":"Abdel-Wahab","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabine","family":"Bleiziffer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Verena","family":"Veulemans","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Sedaghat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matti","family":"Adam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georg","family":"Nickenig","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Malte","family":"Kelm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Holger","family":"Thiele","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephan","family":"Baldus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanja K.","family":"Rudolph","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,11,9]]},"reference":[{"key":"1963_CR1","doi-asserted-by":"publisher","DOI":"10.1097\/01.sa.0000410147.99581.d4","author":"CR Smith","year":"2012","unstructured":"Smith CR, Leon MB, Mack MJ, Miller DC, Moses JW, Svensson LG, Tuzcu EM, Webb JG, Fontana GP, Makkar RR et al (2012) Transcatheter versus surgical aortic-valve replacement in high-risk patients. 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S. Bleiziffer received speaker honoraria from Medtronic and Boston Scientific. VV and MK have received consulting fees, travel expenses, or study honoraria from Medtronic and Edwards Lifesciences. MA reports consulting fees from Edwards Lifescience and Boston Scientific, and institutional grants and consulting fees from Medtronic during the conduct of the study. TKR received speaker\u2019s honoraria from Abbott, Boston Scientific, Edwards Lifesciences and Medtronic and she is a proctor for Edwards Lifesciences. All other authors declare no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}