{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T00:36:58Z","timestamp":1787099818118,"version":"build-2736575974"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2023,11,20]],"date-time":"2023-11-20T00:00:00Z","timestamp":1700438400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2023,11,20]],"date-time":"2023-11-20T00:00:00Z","timestamp":1700438400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"This work was supported by internal funding of the University Heart Center\/Medical Center \u2013 University of Freiburg."},{"name":"Universit\u00e4tsklinikum Freiburg"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Res Cardiol"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Previously, overall comparable outcomes were seen for balloon-expandable (BE) or self-expanding (SE) transfemoral transcatheter aortic valve replacement (TAVR). However, subgroup analyses based on large case numbers are still needed.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>German national data of all BE and SE transfemoral TAVR treating aortic valve stenosis in 2019 and 2020 were analysed. We then compared different outcomes and performed a subgroup analysis for the endpoint in-hospital mortality.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Overall, 46,243\u00a0TAVR were analysed, 19,910 BE, and 26,333 SE. Patients in the SE group had a significantly higher logistic EuroSCORE (13.61 vs 12.66%, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), age (81.55 vs 79.99a, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), and proportion of women (54.82 vs 40.06%, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). Both groups showed a similar in-hospital mortality with 2.37% in BE and 2.35% in SE (<jats:italic>p<\/jats:italic>\u2009=\u20090.916). In-hospital mortality also did not differ significantly after risk adjustment (OR\u2009=\u20090.98 [0.86, 1.13], <jats:italic>p<\/jats:italic>\u2009=\u20090.799). Patients in the SE group had a significantly lower risk of major bleeding (OR\u2009=\u20090.83 [0.73, 0.95], <jats:italic>p<\/jats:italic>\u2009=\u20090.006), but a significantly higher risk of stroke (OR\u2009=\u20091.38 [1.19, 1.59], <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), delirium (OR\u2009=\u20091.15 [1.06, 1.24], <jats:italic>p<\/jats:italic>\u2009=\u20090.001), and permanent pacemaker implantation (OR\u2009=\u20091.29 [1.21, 1.37], <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). In the subgroup analysis of in-hospital mortality, there were no significant differences in any of the observed subgroups (age\u2009&lt;\u200975\/75\u201379\/80\u201384\/\u2009\u2265\u200985a, logistic EuroSCORE\u2009&lt;\u20094\/4\u2013\u2009&lt;\u20099\/\u2009\u2265\u20099, gender, NYHA III\/IV, previous CABG, peripheral vascular disease, COPD, pulmonary hypertension, renal disease GFR\u2009&lt;\u200930\u00a0ml\/min, and diabetes mellitus).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>In the direct comparison of balloon-expandable and self-expanding TAVR, there are no differences for in-hospital mortality in subgroups.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Graphical abstract<\/jats:title>\n                \n              <\/jats:sec>","DOI":"10.1007\/s00392-023-02326-w","type":"journal-article","created":{"date-parts":[[2023,11,20]],"date-time":"2023-11-20T12:02:26Z","timestamp":1700481746000},"page":"168-176","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Comparing balloon-expandable and self-expanding transfemoral transcatheter aortic valve replacement based on subgroups in Germany 2019\/2020"],"prefix":"10.1007","volume":"113","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4460-2102","authenticated-orcid":false,"given":"Vera","family":"Oettinger","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0024-1643","authenticated-orcid":false,"given":"Ingo","family":"Hilgendorf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1525-4348","authenticated-orcid":false,"given":"Dennis","family":"Wolf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9333-3629","authenticated-orcid":false,"given":"Jonathan","family":"Rilinger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0200-7495","authenticated-orcid":false,"given":"Alexander","family":"Maier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manfred","family":"Zehender","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7542-1956","authenticated-orcid":false,"given":"Dirk","family":"Westermann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0837-6945","authenticated-orcid":false,"given":"Klaus","family":"Kaier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2767-8009","authenticated-orcid":false,"given":"Constantin","family":"von zur M\u00fchlen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,11,20]]},"reference":[{"issue":"12","key":"2326_CR1","doi-asserted-by":"publisher","first-page":"1977","DOI":"10.1007\/s00392-021-01928-6","volume":"110","author":"P Stachon","year":"2021","unstructured":"Stachon P, Hehn P, Wolf D, Heidt T, Oettinger V, Zehender M et al (2021) In-hospital outcomes of self-expanding and balloon-expandable transcatheter heart valves in Germany. 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They solely had access to summary results provided by the Research Data Centre. Therefore, according to German law, ethics committee approval and informed consent were not required. All pooled results have been anonymized by DESTATIS. This means that any information that could be used to identify an individual patient or a single center was censored by DESTATIS to ensure privacy. In addition, the data are checked and censored by DESTATIS to prevent any conclusions being drawn about an individual center.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and informed consent"}}]}}