{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T23:47:36Z","timestamp":1773359256949,"version":"3.50.1"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2025,8,19]],"date-time":"2025-08-19T00:00:00Z","timestamp":1755561600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,8,19]],"date-time":"2025-08-19T00:00:00Z","timestamp":1755561600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Res Cardiol"],"published-print":{"date-parts":[[2026,3]]},"DOI":"10.1007\/s00392-025-02732-2","type":"journal-article","created":{"date-parts":[[2025,8,19]],"date-time":"2025-08-19T10:53:37Z","timestamp":1755600817000},"page":"383-394","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Beyond APACHE II: the role of TAPSE in predicting mortality among septic patients and septic shock; a systematic review and metanalysis Right heart, right prognosis: TAPSE, a new tool for predicting mortality among septic patients and septic shock; a systematic review and metanalysis"],"prefix":"10.1007","volume":"115","author":[{"given":"Alessandro","family":"Perencin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chiara","family":"Curreri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruno Micael","family":"Zanforlini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Bertocco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chiara","family":"Ceolin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1579-2202","authenticated-orcid":false,"given":"Mario Virgilio","family":"Papa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Sergi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marina","family":"De Rui","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,8,19]]},"reference":[{"issue":"2","key":"2732_CR1","doi-asserted-by":"publisher","DOI":"10.3390\/pathogens13020181","volume":"13","author":"AM Spagnolo","year":"2024","unstructured":"Spagnolo AM (2024) Bacterial infections: surveillance, prevention and control. Pathogens 13(2):181. https:\/\/doi.org\/10.3390\/pathogens13020181","journal-title":"Pathogens"},{"issue":"3","key":"2732_CR2","doi-asserted-by":"publisher","first-page":"487","DOI":"10.1016\/j.mcna.2018.12.008","volume":"103","author":"CW Lanks","year":"2019","unstructured":"Lanks CW et al (2019) Community-acquired pneumonia and hospital-acquired pneumonia. Med Clin North Am 103(3):487\u2013501. https:\/\/doi.org\/10.1016\/j.mcna.2018.12.008","journal-title":"Med Clin North Am"},{"issue":"4","key":"2732_CR3","doi-asserted-by":"publisher","first-page":"731","DOI":"10.1016\/j.idc.2017.07.010","volume":"31","author":"TA Rowe","year":"2017","unstructured":"Rowe TA, McKoy JM (2017) Sepsis in older adults. Infect Dis Clin North Am 31(4):731\u2013742. https:\/\/doi.org\/10.1016\/j.idc.2017.07.010","journal-title":"Infect Dis Clin North Am"},{"issue":"9","key":"2732_CR4","doi-asserted-by":"publisher","first-page":"840","DOI":"10.1056\/NEJMra1208623","volume":"369","author":"DC Angus","year":"2013","unstructured":"Angus DC, van der Poll T (2013) Severe sepsis and septic shock. N Engl J Med 369(9):840\u201351. https:\/\/doi.org\/10.1056\/NEJMra1208623","journal-title":"N Engl J Med"},{"issue":"5","key":"2732_CR5","doi-asserted-by":"publisher","DOI":"10.1186\/cc8029","volume":"13","author":"M Girardis","year":"2009","unstructured":"Girardis M et al (2009) Effects on management and outcome of severe sepsis and septic shock patients admitted to the intensive care unit after implementation of a sepsis program: a pilot study. Crit Care 13(5):R143. https:\/\/doi.org\/10.1186\/cc8029","journal-title":"Crit Care"},{"key":"2732_CR6","doi-asserted-by":"publisher","unstructured":"Thakur R et al. (2023) Mean SOFA score in comparison with APACHE II score in predicting mortality in surgical patients with sepsis. Cureus 15,3 e36653. https:\/\/doi.org\/10.7759\/cureus.36653","DOI":"10.7759\/cureus.36653"},{"key":"2732_CR7","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1016\/j.ijid.2021.02.029","volume":"105","author":"JW Martha","year":"2021","unstructured":"Martha JW, Pranata R, Wibowo A, Lim MA (2021) Tricuspid annular plane systolic excursion (TAPSE) measured by echocardiography and mortality in COVID-19: a systematic review and meta-analysis. Int J Infect Dis 105:351\u2013356. https:\/\/doi.org\/10.1016\/j.ijid.2021.02.029","journal-title":"Int J Infect Dis"},{"key":"2732_CR8","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2023.131358","volume":"394","author":"Q Li","year":"2024","unstructured":"Li Q, Zhang M (2024) Echocardiography assessment of right ventricular-pulmonary artery coupling: validation of surrogates and clinical utilities. Int J Cardiol 394:131358. https:\/\/doi.org\/10.1016\/j.ijcard.2023.131358","journal-title":"Int J Cardiol"},{"key":"2732_CR9","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n71","volume":"372","author":"MJ Page","year":"2021","unstructured":"Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD et al (2021) The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ 372:n71","journal-title":"BMJ"},{"key":"2732_CR10","unstructured":"Wells G, Shea B, O\u2019Connell D, Robertson J, Peterson J, Losos M, Tugwell P (2025) The Newcastle-Ottawa Scale (NOS) for Assessing the Quality of Nonrandomized Studies in Meta-Analysis. Available online: https:\/\/www.google.com.hk\/url?sa=t&source=web&rct=j&opi=89978449&url=http:\/\/www.evidencebasedpublichealth.de\/download\/Newcastle_Ottowa_Scale_Pope_Bruce.pdf&ved=2ahUKEwiin9PIrfWMAxU48DQHHY97GaIQFnoECBcQAQ&usg=AOvVaw1uMVAPUhnxn_VNxMRTmSFm (accessed on 5 March 2025)"},{"issue":"3","key":"2732_CR11","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1016\/j.tjem.2018.08.001","volume":"18","author":"H Akoglu","year":"2018","unstructured":"Akoglu H (2018) User\u2019s guide to correlation coefficients. Turk J Emerg Med 18(3):91\u201393","journal-title":"Turk J Emerg Med"},{"issue":"11","key":"2732_CR12","doi-asserted-by":"publisher","first-page":"1854","DOI":"10.1111\/imj.14957","volume":"51","author":"J Dong","year":"2021","unstructured":"Dong J, White S, Nielsen K, Banchs J, Wang J, Botz GH, Nates JL (2021) Tricuspid annular plane systolic excursion is a predictor of mortality for septic shock. Intern Med J 51(11):1854\u20131861. https:\/\/doi.org\/10.1111\/imj.14957","journal-title":"Intern Med J"},{"issue":"10","key":"2732_CR13","doi-asserted-by":"publisher","first-page":"1169","DOI":"10.4103\/0366-6999.205856","volume":"130","author":"HM Zhang","year":"2017","unstructured":"Zhang HM, Wang XT, Zhang LN, He W, Zhang Q, Liu DW, Chinese Critical Ultrasound Study Group (2017) Left ventricular longitudinal systolic function in septic shock patients with normal ejection fraction: a case-control study. Chin Med J Engl 130(10):1169\u20131174. https:\/\/doi.org\/10.4103\/0366-6999.205856","journal-title":"Chin Med J Engl"},{"issue":"3","key":"2732_CR14","doi-asserted-by":"publisher","first-page":"1055","DOI":"10.1016\/j.chest.2020.09.274","volume":"159","author":"MJ Lanspa","year":"2021","unstructured":"Lanspa MJ, Cirulis MM, Wiley BM, Olsen TD, Wilson EL, Beesley SJ, Brown SM, Hirshberg EL, Grissom CK (2021) Right ventricular dysfunction in early sepsis and septic shock. Chest 159(3):1055\u20131063. https:\/\/doi.org\/10.1016\/j.chest.2020.09.274","journal-title":"Chest"},{"issue":"2","key":"2732_CR15","doi-asserted-by":"publisher","first-page":"348","DOI":"10.5811\/westjem.2019.11.44968","volume":"21","author":"S Lahham","year":"2020","unstructured":"Lahham S, Lee C, Ali Q, Moeller J, Fischetti C, Thompson M, Saadat S, Fox JC (2020) Tricuspid annular plane of systolic excursion (TAPSE) for the evaluation of patients with severe sepsis and septic shock. West J Emerg Med 21(2):348\u2013352. https:\/\/doi.org\/10.5811\/westjem.2019.11.44968","journal-title":"West J Emerg Med"},{"issue":"1","key":"2732_CR16","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1186\/s12947-020-00198-y","volume":"18","author":"H Zhang","year":"2020","unstructured":"Zhang H, Lian H, Zhang Q, Chen X, Wang X, Liu D (2020) Prognostic implications of tricuspid annular plane systolic excursion\/pulmonary arterial systolic pressure ratio in septic shock patients. Cardiovasc Ultrasound 18(1):20. https:\/\/doi.org\/10.1186\/s12947-020-00198-y","journal-title":"Cardiovasc Ultrasound"},{"issue":"3","key":"2732_CR17","doi-asserted-by":"publisher","first-page":"757","DOI":"10.1007\/s11739-020-02545-3","volume":"16","author":"F Innocenti","year":"2021","unstructured":"Innocenti F, Palmieri V, Stefanone VT, D\u2019Argenzio F, Cigana M, Montuori M, Capretti E, De Paris A, Calcagno S, Tassinari I, Pini R (2021) Prognostic stratification in septic patients with overt and cryptic shock by speckle tracking echocardiography. Intern Emerg Med 16(3):757\u2013764. https:\/\/doi.org\/10.1007\/s11739-020-02545-3","journal-title":"Intern Emerg Med"},{"issue":"6","key":"2732_CR18","doi-asserted-by":"publisher","first-page":"502","DOI":"10.1097\/MAT.0000000000002131","volume":"70","author":"J Forner","year":"2024","unstructured":"Forner J, Weidner K, Rusnak J, Dudda J, Behnes M, Akin I, Schupp T (2024) Prognostic impact of left compared to right heart function in sepsis and septic shock. ASAIO J 70(6):502\u2013509. https:\/\/doi.org\/10.1097\/MAT.0000000000002131","journal-title":"ASAIO J"},{"issue":"1","key":"2732_CR19","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1097\/SHK.0000000000002142","volume":"60","author":"Q Ma","year":"2023","unstructured":"Ma Q, Ding C, Jiang F, Hu G, Wu J, Zhang X (2023) Respiratory variability of valvular peak systolic velocity as a new indicator of fluid responsiveness in patients with septic shock. Shock 60(1):11\u201317. https:\/\/doi.org\/10.1097\/SHK.0000000000002142","journal-title":"Shock"},{"issue":"7","key":"2732_CR20","doi-asserted-by":"publisher","first-page":"e0269814","DOI":"10.1371\/journal.pone.0269814","volume":"17","author":"RR Ehrman","year":"2022","unstructured":"Ehrman RR, Favot MJ, Harrison NE, Khait L, Ottenhoff JE, Welch RD, Levy PD, Sherwin RL (2022) Early echocardiographic assessment of cardiac function may be prognostically informative in unresuscitated patients with sepsis: a prospective observational study. PLoS One 17(7):e0269814. https:\/\/doi.org\/10.1371\/journal.pone.0269814","journal-title":"PLoS One"},{"issue":"4","key":"2732_CR21","first-page":"11","volume":"70","author":"DN Morkar","year":"2022","unstructured":"Morkar DN, Dwivedi M, Patil P (2022) Comparative study of sofa, Apache II, SAPS II, as a predictor of mortality in patients of sepsis admitted in medical ICU. J Assoc Physicians India 70(4):11\u201312","journal-title":"J Assoc Physicians India"},{"issue":"225","key":"2732_CR22","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1016\/j.ijcard.2016.10.009","volume":"15","author":"E Aloia","year":"2016","unstructured":"Aloia E, Cameli M, D\u2019Ascenzi F, Sciaccaluga C, Mondillo S (2016) TAPSE: An old but useful tool in different diseases. Int J Cardiol 15(225):177\u2013183. https:\/\/doi.org\/10.1016\/j.ijcard.2016.10.009","journal-title":"Int J Cardiol"},{"issue":"2025","key":"2732_CR23","doi-asserted-by":"publisher","first-page":"5511135","DOI":"10.1155\/ccrp\/5511135","volume":"14","author":"S Koowattanatianchai","year":"2025","unstructured":"Koowattanatianchai S, Kochaiyapatana P, Eungsuwat N, Rangsrisaeneepitak V, Thammakumpee K, Kaladee K (2025) Significance of right ventricular dysfunction in predicting short-term survival among patients with sepsis and septic shock: a prognostic analysis. Crit Care Res Pract 14(2025):5511135. https:\/\/doi.org\/10.1155\/ccrp\/5511135","journal-title":"Crit Care Res Pract"},{"key":"2732_CR24","doi-asserted-by":"publisher","unstructured":"Pope MK, Chugh H, Sargsyan A, Uy-Evanado A, Salvucci A, Jui J, Reinier K, Chugh SS (2025) Temporal trends in left ventricular ejection fraction prior to sudden death in heart failure patients. Heart Rhythm S1547\u20135271(25)02436\u20131. https:\/\/doi.org\/10.1016\/j.hrthm.2025.05.013","DOI":"10.1016\/j.hrthm.2025.05.013"},{"issue":"4","key":"2732_CR25","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1111\/j.1540-8175.2010.01354.x","volume":"28","author":"J Xu","year":"2011","unstructured":"Xu J, Peng Y, Li C, Zhang J, Zhou C, Huang L, Xia C, Tang H, Rao L (2011) Feasibility of assessing cardiac systolic function using longitudinal fractional shortening calculated by two-dimensional speckle tracking echocardiography. Echocardiography 28(4):402\u2013407. https:\/\/doi.org\/10.1111\/j.1540-8175.2010.01354.x","journal-title":"Echocardiography"},{"issue":"41 Suppl 7","key":"2732_CR26","doi-asserted-by":"publisher","first-page":"S504","DOI":"10.1086\/432007","volume":"15","author":"SM Opal","year":"2005","unstructured":"Opal SM, Girard TD, Ely EW (2005) The immunopathogenesis of sepsis in elderly patients. Clin Infect Dis 15(41 Suppl 7):S504\u2013S512. https:\/\/doi.org\/10.1086\/432007","journal-title":"Clin Infect Dis"}],"container-title":["Clinical Research in Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00392-025-02732-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00392-025-02732-2","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00392-025-02732-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T07:58:09Z","timestamp":1770796689000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00392-025-02732-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,19]]},"references-count":26,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["2732"],"URL":"https:\/\/doi.org\/10.1007\/s00392-025-02732-2","relation":{},"ISSN":["1861-0684","1861-0692"],"issn-type":[{"value":"1861-0684","type":"print"},{"value":"1861-0692","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,19]]},"assertion":[{"value":"28 May 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 July 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 August 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable. This is a systematic review of previous published papers. Ethical approval was not required for this secondary research.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"Not applicable. This is a systematic review of previous published papers.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Human Ethics and consent to partecipate"}},{"value":"Not applicable.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Clinical trial number"}},{"value":"The authors declare no competing interests.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}