{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T19:22:02Z","timestamp":1790709722439,"version":"4.1.0"},"reference-count":25,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T00:00:00Z","timestamp":1757548800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T00:00:00Z","timestamp":1757548800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/100010447","name":"DZHK","doi-asserted-by":"crossref","award":["81X1600607"],"award-info":[{"award-number":["81X1600607"]}],"id":[{"id":"10.13039\/100010447","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100005713","name":"Technische Universit\u00e4t M\u00fcnchen","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100005713","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Res Cardiol"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>In elderly patients with severe aortic stenosis (AS), concomitant coronary artery disease (CAD) is common. Escpecially for intermediate-risk patients eligible for both interventional and surgical treatment, long-term benefit of either approach remains unclear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To compare long-term outcomes of TAVI\u2009+\u2009PCI versus SAVR\u2009+\u2009CABG in intermediate-risk AS-CAD patients (logistic EuroSCORE 10\u201320%, EuroSCORE II 4\u20139%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective multicentre study included 366 patients treated between 2012 and 2020: 211 underwent TAVI\u2009+\u2009PCI and 155 received SAVR\u2009+\u2009CABG. The primary endpoint was all-cause mortality up to three years; secondary outcomes followed VARC-3 criteria.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Mortality rates were similar at 30\u00a0days (4.8% vs. 8.4%, p\u2009=\u20090.16), six months (12.4% each), one year (18.1% vs. 15.7%) and two years (24.9% vs. 20.1%). At three years, mortality was higher after TAVI\u2009+\u2009PCI (37.1% vs. 25.5%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.02), though CAD complexity was greater in the SAVR\u2009+\u2009CABG group (SYNTAX Score 22.2 vs. 15.9,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). TAVI\u2009+\u2009PCI patients were older (81.1 vs. 78.5\u00a0years,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), but surgical risk was comparable (EuroSCORE II 6.4% vs. 6.2%). Surgical patients experienced more complications, including delirium, stroke, acute kidney injury, major bleedings and transfusion needs. After propensity score matching (154 patients per group), 3-year mortality no longer differed significantly (33.8% vs. 25.9%, p\u2009=\u20090.14).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Both TAVI\u2009+\u2009PCI and SAVR\u2009+\u2009CABG yield comparable long-term outcomes in intermediate-risk AS-CAD patients. Although early complications were more common with surgery, there was a trend towards improved long-term survival.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00392-025-02755-9","type":"journal-article","created":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T14:20:40Z","timestamp":1757600440000},"page":"1188-1198","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["TAVI plus PCI versus SAVR plus CABG: Long-term outcome of a multicentre-registry"],"prefix":"10.1007","volume":"115","author":[{"given":"A.","family":"Stundl","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-7352-1987","authenticated-orcid":false,"given":"L.","family":"Preuss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Prinzing","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. 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