{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T07:57:29Z","timestamp":1763625449416,"version":"3.45.0"},"reference-count":41,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T00:00:00Z","timestamp":1763596800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T00:00:00Z","timestamp":1763596800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82370316","82200350"],"award-info":[{"award-number":["82370316","82200350"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014137","name":"Shanghai Shenkang Hospital Development Center","doi-asserted-by":"publisher","award":["SHDC2022CRD044","SHDC12025136"],"award-info":[{"award-number":["SHDC2022CRD044","SHDC12025136"]}],"id":[{"id":"10.13039\/501100014137","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Three-year action plan for strengthening the construction of the public health system in Shanghai","award":["GWVI-11.2-YQ15"],"award-info":[{"award-number":["GWVI-11.2-YQ15"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Res Cardiol"],"DOI":"10.1007\/s00392-025-02786-2","type":"journal-article","created":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T07:52:21Z","timestamp":1763625141000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A novel technique for vein of Marshall blood sampling and its application in assessing atrial remodeling in atrial fibrillation"],"prefix":"10.1007","author":[{"given":"Jiali","family":"Yuan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hong","family":"Peng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jingqing","family":"Ma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhengshuai","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yaqin","family":"Han","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuepeng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yihui","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6643-400X","authenticated-orcid":false,"given":"Qunshan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yigang","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,11,20]]},"reference":[{"key":"2786_CR1","doi-asserted-by":"publisher","first-page":"ITC97","DOI":"10.7326\/AITC202307180","volume":"176","author":"SM Al-Khatib","year":"2023","unstructured":"Al-Khatib SM (2023) Atrial fibrillation. Ann Intern Med 176:ITC97\u2013ITC112","journal-title":"Ann Intern Med"},{"key":"2786_CR2","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1001\/jama.2024.22451","volume":"333","author":"D Ko","year":"2025","unstructured":"Ko D, Chung MK, Evans PT, Benjamin EJ, Helm RH (2025) Atrial fibrillation: a review. JAMA 333:329\u2013342","journal-title":"JAMA"},{"key":"2786_CR3","doi-asserted-by":"publisher","first-page":"6","DOI":"10.3390\/ijms23010006","volume":"23","author":"M Sagris","year":"2021","unstructured":"Sagris M, Vardas EP, Theofilis P, Antonopoulos AS, Oikonomou E, Tousoulis D (2021) Atrial fibrillation: pathogenesis, predisposing factors, and genetics. Int J Mol Sci 23:6","journal-title":"Int J Mol Sci"},{"issue":"149","key":"2786_CR4","first-page":"e1","volume":"2024","author":"JA Joglar","year":"2023","unstructured":"Joglar JA, Chung MK, Armbruster AL, Benjamin EJ, Chyou JY, Cronin EM, Deswal A, Eckhardt LL, Goldberger ZD, Gopinathannair R, Gorenek B, Hess PL, Hlatky M, Hogan G, Ibeh C, Indik JH, Kido K, Kusumoto F, Link MS, Linta KT, Marcus GM, McCarthy PM, Patel N, Patton KK, Perez MV, Piccini JP, Russo AM, Sanders P, Streur MM, Thomas KL, Times S, Tisdale JE, Valente AM, Van Wagoner DR, Members PRC (2023) ACC\/AHA\/ACCP\/HRS guideline for the diagnosis and management of atrial fibrillation: a report of the American College of Cardiology\/American Heart Association Joint Committee on clinical practice guidelines. Circulation 2024(149):e1\u2013e156","journal-title":"Circulation"},{"key":"2786_CR5","doi-asserted-by":"publisher","first-page":"3768","DOI":"10.1002\/ehf2.14089","volume":"9","author":"M Li","year":"2022","unstructured":"Li M, Ning Y, Tse G, Saguner AM, Wei M, Day JD, Luo G, Li G (2022) Atrial cardiomyopathy: from cell to bedside. ESC Heart Fail 9:3768\u20133784","journal-title":"ESC Heart Fail"},{"key":"2786_CR6","doi-asserted-by":"publisher","first-page":"4430","DOI":"10.3390\/jcm10194430","volume":"10","author":"G Sygitowicz","year":"2021","unstructured":"Sygitowicz G, Maciejak-Jastrz\u0119bska A, Sitkiewicz D (2021) A review of the molecular mechanisms underlying cardiac fibrosis and atrial fibrillation. J Clin Med 10:4430","journal-title":"J Clin Med"},{"key":"2786_CR7","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1016\/j.jacep.2022.01.019","volume":"8","author":"A Frontera","year":"2022","unstructured":"Frontera A, Pagani S, Limite LR, Peirone A, Fioravanti F, Enache B, Cuellar Silva J, Vlachos K, Meyer C, Montesano G, Manzoni A, Ded\u00e9 L, Quarteroni A, La\u021bcu DG, Rossi P, Della Bella P (2022) Slow conduction corridors and pivot sites characterize the electrical remodeling in atrial fibrillation. JACC Clin Electrophysiol 8:561\u2013577","journal-title":"JACC Clin Electrophysiol"},{"key":"2786_CR8","doi-asserted-by":"publisher","first-page":"1832","DOI":"10.1136\/heartjnl-2013-304724","volume":"99","author":"KK Patton","year":"2013","unstructured":"Patton KK, Heckbert SR, Alonso A, Bahrami H, Lima JAC, Burke G, Kronmal RA (2013) N-terminal pro-B-type natriuretic peptide as a predictor of incident atrial fibrillation in the Multi-Ethnic Study of Atherosclerosis: the effects of age, sex and ethnicity. Heart 99:1832\u20131836","journal-title":"Heart"},{"key":"2786_CR9","doi-asserted-by":"publisher","first-page":"230","DOI":"10.1038\/nrcardio.2015.194","volume":"13","author":"L Fabritz","year":"2016","unstructured":"Fabritz L, Guasch E, Antoniades C, Bardinet I, Benninger G, Betts TR, Brand E, Breithardt G, Bucklar-Suchankova G, Camm AJ, Cartlidge D, Casadei B, Chua WWL, Crijns HJGM, Deeks J, Hatem S, Hidden-Lucet F, K\u00e4\u00e4b S, Maniadakis N, Martin S, Mont L, Reinecke H, Sinner MF, Schotten U, Southwood T, Stoll M, Vardas P, Wakili R, West A, Ziegler A, Kirchhof P (2016) Expert consensus document: defining the major health modifiers causing atrial fibrillation: a roadmap to underpin personalized prevention and treatment. Nat Rev Cardiol 13:230\u2013237","journal-title":"Nat Rev Cardiol"},{"key":"2786_CR10","doi-asserted-by":"publisher","first-page":"1268","DOI":"10.1093\/eurheartj\/ehy815","volume":"40","author":"W Chua","year":"2019","unstructured":"Chua W, Purmah Y, Cardoso VR, Gkoutos GV, Tull SP, Neculau G, Thomas MR, Kotecha D, Lip GYH, Kirchhof P, Fabritz L (2019) Data-driven discovery and validation of circulating blood-based biomarkers associated with prevalent atrial fibrillation. Eur Heart J 40:1268\u20131276","journal-title":"Eur Heart J"},{"key":"2786_CR11","doi-asserted-by":"crossref","unstructured":"Reyat JS, Chua W, Cardoso VR, Witten A, Kastner PM, Kabir SN, Sinner MF, Wesselink R, Holmes AP, Pavlovic D, Stoll M, K\u00e4\u00e4b S, Gkoutos GV, de Groot JR, Kirchhof P, Fabritz L. Reduced left atrial cardiomyocyte PITX2 and elevated circulating BMP10 predict atrial fibrillation after ablation. JCI Insight 5:e139179","DOI":"10.1172\/jci.insight.139179"},{"key":"2786_CR12","doi-asserted-by":"publisher","first-page":"16743","DOI":"10.1038\/s41598-023-42331-7","volume":"13","author":"W Chua","year":"2023","unstructured":"Chua W, Cardoso VR, Guasch E, Sinner MF, Al-Taie C, Brady P, Casadei B, Crijns HJGM, Dudink EAMP, Hatem SN, K\u00e4\u00e4b S, Kastner P, Mont L, Nehaj F, Purmah Y, Reyat JS, Schotten U, Sommerfeld LC, Zeemering S, Ziegler A, Gkoutos GV, Kirchhof P, Fabritz L (2023) An angiopoietin 2, FGF23, and BMP10 biomarker signature differentiates atrial fibrillation from other concomitant cardiovascular conditions. Sci Rep 13:16743","journal-title":"Sci Rep"},{"key":"2786_CR13","doi-asserted-by":"publisher","first-page":"e028255","DOI":"10.1161\/JAHA.122.028255","volume":"12","author":"E Hennings","year":"2023","unstructured":"Hennings E, Blum S, Aeschbacher S, Coslovsky M, Knecht S, Eken C, Lischer M, Paladini RE, Krisai P, Reichlin T, Rodondi N, Beer JH, Ammann P, Conte G, De Perna ML, Kobza R, Blum MR, Bossard M, Kastner P, Ziegler A, M\u00fcller C, Bonati LH, Pfister O, Zuern CS, Conen D, K\u00fchne M, Osswald S, Swiss-AF Investigators (2023) Bone morphogenetic protein 10-a novel biomarker to predict adverse outcomes in patients with atrial fibrillation. J Am Heart Assoc 12:e028255","journal-title":"J Am Heart Assoc"},{"key":"2786_CR14","doi-asserted-by":"publisher","first-page":"855","DOI":"10.1093\/cvr\/cvae067","volume":"120","author":"L Fabritz","year":"2024","unstructured":"Fabritz L, Chua W, Cardoso VR, Al-Taie C, Borof K, Suling A, Krause L, Kany S, Magnussen C, Wegscheider K, Breithardt G, Crijns HJGM, Camm AJ, Gkoutos G, Ellinor PT, Goette A, Schotten U, Wienhues-Thelen U-H, Zeller T, Schnabel RB, Zapf A, Kirchhof P (2024) Blood-based cardiometabolic phenotypes in atrial fibrillation and their associated risk: EAST-AFNET 4 biomolecule study. Cardiovasc Res 120:855\u2013868","journal-title":"Cardiovasc Res"},{"key":"2786_CR15","doi-asserted-by":"publisher","first-page":"5002","DOI":"10.1093\/eurheartj\/ehae611","volume":"45","author":"L Fabritz","year":"2024","unstructured":"Fabritz L, Al-Taie C, Borof K, Breithardt G, Camm AJ, Crijns HJGM, Roth Cardoso V, Chua W, van Elferen S, Eckardt L, Gkoutos G, Goette A, Guasch E, Hatem S, Metzner A, Mont L, Murukutla VA, Obergassel J, Rillig A, Sinner MF, Schnabel RB, Schotten U, Sommerfeld LC, Wienhues-Thelen U-H, Zapf A, Zeller T, Kirchhof P (2024) Biomarker-based prediction of sinus rhythm in atrial fibrillation patients: the EAST-AFNET 4 biomolecule study. Eur Heart J 45:5002\u20135019","journal-title":"Eur Heart J"},{"key":"2786_CR16","doi-asserted-by":"publisher","first-page":"e033720","DOI":"10.1161\/JAHA.123.033720","volume":"13","author":"KI Gkarmiris","year":"2024","unstructured":"Gkarmiris KI, Lindb\u00e4ck J, Alexander JH, Granger CB, Kastner P, Lopes RD, Ziegler A, Oldgren J, Siegbahn A, Wallentin L, Hijazi Z (2024) Repeated measurement of the novel atrial biomarker BMP10 (bone morphogenetic protein 10) refines risk stratification in anticoagulated patients with atrial fibrillation: insights from the ARISTOTLE trial. J Am Heart Assoc 13:e033720","journal-title":"J Am Heart Assoc"},{"key":"2786_CR17","doi-asserted-by":"publisher","DOI":"10.1007\/s00392-024-02584-2","author":"J Simonavicius","year":"2024","unstructured":"Simonavicius J, Wussler D, Belkin M, Luening K, Lopez-Ayala P, Strebel I, Shrestha S, Nowak A, Michou E, Papachristou A, Popescu C, Kozhuharov N, Sabti Z, Reiffer Z, Hennings E, Zimmermann T, Diebold M, Breidthardt T, Mueller C (2024) Diagnostic and prognostic utility of bone morphogenetic protein 10 in acute dyspnea: a cohort study. Clin Res Cardiol. https:\/\/doi.org\/10.1007\/s00392-024-02584-2","journal-title":"Clin Res Cardiol"},{"key":"2786_CR18","doi-asserted-by":"publisher","first-page":"593","DOI":"10.1016\/j.hrthm.2015.10.018","volume":"13","author":"M Rodr\u00edguez-Ma\u00f1ero","year":"2016","unstructured":"Rodr\u00edguez-Ma\u00f1ero M, Schurmann P, Valderr\u00e1bano M (2016) Ligament and vein of Marshall: a therapeutic opportunity in atrial fibrillation. Heart Rhythm 13:593\u2013601","journal-title":"Heart Rhythm"},{"key":"2786_CR19","doi-asserted-by":"publisher","first-page":"1892","DOI":"10.1016\/j.jacc.2014.01.032","volume":"63","author":"JL B\u00e1ez-Escudero","year":"2014","unstructured":"B\u00e1ez-Escudero JL, Keida T, Dave AS, Okishige K, Valderr\u00e1bano M (2014) Ethanol infusion in the vein of Marshall leads to parasympathetic denervation of the human left atrium: implications for atrial fibrillation. J Am Coll Cardiol 63:1892\u20131901","journal-title":"J Am Coll Cardiol"},{"key":"2786_CR20","doi-asserted-by":"publisher","first-page":"1552","DOI":"10.1016\/j.hrthm.2009.07.036","volume":"6","author":"M Valderr\u00e1bano","year":"2009","unstructured":"Valderr\u00e1bano M, Liu X, Sasaridis C, Sidhu J, Little S, Khoury DS (2009) Ethanol infusion in the vein of Marshall: adjunctive effects during ablation of atrial fibrillation. Heart Rhythm 6:1552\u20131558","journal-title":"Heart Rhythm"},{"key":"2786_CR21","doi-asserted-by":"publisher","first-page":"1074","DOI":"10.1016\/j.hrthm.2021.03.032","volume":"18","author":"M Valderr\u00e1bano","year":"2021","unstructured":"Valderr\u00e1bano M (2021) Vein of Marshall ethanol infusion in the treatment of atrial fibrillation: from concept to clinical practice. Heart Rhythm 18:1074\u20131082","journal-title":"Heart Rhythm"},{"key":"2786_CR22","doi-asserted-by":"publisher","first-page":"873","DOI":"10.2174\/0929867324666170830100424","volume":"26","author":"E Oikonomou","year":"2019","unstructured":"Oikonomou E, Zografos T, Papamikroulis G-A, Siasos G, Vogiatzi G, Theofilis P, Briasoulis A, Papaioannou S, Vavuranakis M, Gennimata V, Tousoulis D (2019) Biomarkers in atrial fibrillation and heart failure. Curr Med Chem 26:873\u2013887","journal-title":"Curr Med Chem"},{"issue":"Suppl B","key":"2786_CR23","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1093\/eurheartj\/8.suppl_B.99","volume":"8","author":"H Ruskoaho","year":"1987","unstructured":"Ruskoaho H, Lang RE, Toth M, Ganten D, Unger T (1987) Release and regulation of atrial natriuretic peptide (ANP). Eur Heart J 8(Suppl B):99\u2013109","journal-title":"Eur Heart J"},{"key":"2786_CR24","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1016\/j.jacbts.2021.11.007","volume":"7","author":"DM Kaye","year":"2022","unstructured":"Kaye DM, Nanayakkara S, Wang B, Shihata W, Marques FZ, Esler M, Lambert G, Mariani J (2022) Characterization of cardiac sympathetic nervous system and inflammatory activation in HFpEF patients. JACC Basic Transl Sci 7:116\u2013127","journal-title":"JACC Basic Transl Sci"},{"key":"2786_CR25","doi-asserted-by":"publisher","first-page":"e13174","DOI":"10.1111\/eci.13174","volume":"49","author":"AA Khan","year":"2019","unstructured":"Khan AA, Lip GYH, Shantsila A (2019) Heart rate variability in atrial fibrillation: the balance between sympathetic and parasympathetic nervous system. Eur J Clin Invest 49:e13174","journal-title":"Eur J Clin Invest"},{"key":"2786_CR26","doi-asserted-by":"publisher","unstructured":"Sang C, Liu Q, Lai Y, Xia S, Jiang R, Li S, Guo Q, Li Q, Gao M, Guo X, Huang L, Liu N, Jiang C, Zuo S, Liu X, Li M, Ge W, Song S, Chen L, Xie S, Zou J, Chen K, Liu X, Hu H, Wang X, Zhang J, Wang Z, Wang C, He L, Jiang C, Tang R, Zhou N, Wang Y, Long D, Du X, Jiang C, Macle L, Dong J, Ma C, PROMPT-AF investigators (2025) Pulmonary vein isolation with optimized linear ablation vs pulmonary vein isolation alone for persistent AF: the PROMPT-AF randomized clinical trial. JAMA 333(5):381\u2013389. https:\/\/doi.org\/10.1001\/jama.2024.24438","DOI":"10.1001\/jama.2024.24438"},{"key":"2786_CR27","doi-asserted-by":"publisher","first-page":"eadl4374","DOI":"10.1126\/sciadv.adl4374","volume":"10","author":"D Carper","year":"2024","unstructured":"Carper D, Lac M, Coue M, Labour A, M\u00e4rtens A, Banda JAA, Mazeyrie L, Mechta M, Ingerslev LR, Elhadad M, Petit JV, Maslo C, Monbrun L, Del Carmine P, Sainte-Marie Y, Bourlier V, Laurens C, Mithieux G, Joanisse DR, Coudray C, Feillet-Coudray C, Montastier E, Viguerie N, Tavernier G, Waldenberger M, Peters A, Wang-Sattler R, Adamski J, Suhre K, Gieger C, Kastenm\u00fcller G, Illig T, Lichtinghagen R, Seissler J, Mounier R, Hiller K, Jordan J, Barr\u00e8s R, Kuhn M, Pesta D, Moro C (2024) Loss of atrial natriuretic peptide signaling causes insulin resistance, mitochondrial dysfunction, and low endurance capacity. Sci Adv 10:eadl4374","journal-title":"Sci Adv"},{"key":"2786_CR28","doi-asserted-by":"publisher","first-page":"H590","DOI":"10.1152\/ajpheart.00612.2017","volume":"315","author":"R Tan","year":"2018","unstructured":"Tan R, Ahn YM, Kim HY, Lee YJ, Cho KW, Kang DG, Lee HS (2018) Atrial secretion of ANP is suppressed in renovascular hypertension: shifting of ANP secretion from atria to the left ventricle. Am J Physiol Heart Circ Physiol 315:H590\u2013H601","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"2786_CR29","doi-asserted-by":"publisher","first-page":"6470","DOI":"10.3390\/ijms24076470","volume":"24","author":"F Rahbar Kouibaran","year":"2023","unstructured":"Rahbar Kouibaran F, Sabatino M, Barozzi C, Diemberger I (2023) Atrial natriuretic peptides as a bridge between atrial fibrillation, heart failure, and amyloidosis of the atria. Int J Mol Sci 24:6470","journal-title":"Int J Mol Sci"},{"key":"2786_CR30","doi-asserted-by":"publisher","first-page":"451","DOI":"10.1016\/j.jacc.2020.04.080","volume":"76","author":"MA Nazari","year":"2020","unstructured":"Nazari MA, Rosenblum JS, Haigney MC, Rosing DR, Pacak K (2020) Pathophysiology and acute management of tachyarrhythmias in pheochromocytoma: JACC review topic of the week. J Am Coll Cardiol 76:451\u2013464","journal-title":"J Am Coll Cardiol"},{"key":"2786_CR31","doi-asserted-by":"publisher","first-page":"e0133664","DOI":"10.1371\/journal.pone.0133664","volume":"10","author":"K Suita","year":"2015","unstructured":"Suita K, Fujita T, Hasegawa N, Cai W, Jin H, Hidaka Y, Prajapati R, Umemura M, Yokoyama U, Sato M, Okumura S, Ishikawa Y (2015) Norepinephrine-induced adrenergic activation strikingly increased the atrial fibrillation duration through \u03b21- and \u03b11-adrenergic receptor-mediated signaling in mice. PLoS ONE 10:e0133664","journal-title":"PLoS ONE"},{"key":"2786_CR32","doi-asserted-by":"publisher","first-page":"1133","DOI":"10.1136\/heartjnl-2014-307334","volume":"101","author":"K Yoshida","year":"2015","unstructured":"Yoshida K, Kaneshiro T, Ito Y, Kimata A, Koda N, Hiraya D, Baba M, Misaki M, Takeyasu N, Yamaguchi I, Aonuma K (2015) Elevated plasma norepinephrine level and sick sinus syndrome in patients with lone atrial fibrillation. Heart 101:1133\u20131138","journal-title":"Heart"},{"key":"2786_CR33","doi-asserted-by":"publisher","first-page":"977","DOI":"10.1093\/oxfordjournals.eurheartj.a061034","volume":"16","author":"M Arakawa","year":"1995","unstructured":"Arakawa M, Miwa H, Noda T, Ito Y, Kambara K, Kagawa K, Nishigaki K, Kano A, Hirakawa S (1995) Alternations in atrial natriuretic peptide release after DC cardioversion of non-valvular chronic atrial fibrillation. Eur Heart J 16:977\u2013985","journal-title":"Eur Heart J"},{"key":"2786_CR34","doi-asserted-by":"publisher","first-page":"1004","DOI":"10.1161\/CIRCRESAHA.113.302549","volume":"114","author":"MJ Shen","year":"2014","unstructured":"Shen MJ, Zipes DP (2014) Role of the autonomic nervous system in modulating cardiac arrhythmias. Circ Res 114:1004\u20131021","journal-title":"Circ Res"},{"key":"2786_CR35","doi-asserted-by":"publisher","first-page":"2022","DOI":"10.1016\/j.jacc.2017.09.002","volume":"70","author":"CJ Lavie","year":"2017","unstructured":"Lavie CJ, Pandey A, Lau DH, Alpert MA, Sanders P (2017) Obesity and atrial fibrillation prevalence, pathogenesis, and prognosis: effects of weight loss and exercise. J Am Coll Cardiol 70:2022\u20132035","journal-title":"J Am Coll Cardiol"},{"key":"2786_CR36","doi-asserted-by":"publisher","first-page":"1107","DOI":"10.1016\/j.jacc.2019.07.020","volume":"74","author":"A Wang","year":"2019","unstructured":"Wang A, Green JB, Halperin JL, Piccini JP (2019) Atrial fibrillation and diabetes mellitus: JACC review topic of the week. J Am Coll Cardiol 74:1107\u20131115","journal-title":"J Am Coll Cardiol"},{"key":"2786_CR37","doi-asserted-by":"publisher","first-page":"682","DOI":"10.1038\/s41569-024-01038-6","volume":"21","author":"D Bode","year":"2024","unstructured":"Bode D, Pronto JRD, Schiattarella GG, Voigt N (2024) Metabolic remodelling in atrial fibrillation: manifestations, mechanisms and clinical implications. Nat Rev Cardiol 21:682\u2013700","journal-title":"Nat Rev Cardiol"},{"key":"2786_CR38","doi-asserted-by":"publisher","first-page":"364","DOI":"10.1126\/science.abc8861","volume":"370","author":"D Murashige","year":"2020","unstructured":"Murashige D, Jang C, Neinast M, Edwards JJ, Cowan A, Hyman MC, Rabinowitz JD, Frankel DS, Arany Z (2020) Comprehensive quantification of fuel use by the failing and nonfailing human heart. Science 370:364\u2013368","journal-title":"Science"},{"key":"2786_CR39","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1016\/j.hrthm.2009.10.004","volume":"7","author":"GM Marcus","year":"2010","unstructured":"Marcus GM, Smith LM, Ordovas K, Scheinman MM, Kim AM, Badhwar N, Lee RJ, Tseng ZH, Lee BK, Olgin JE (2010) Intracardiac and extracardiac markers of inflammation during atrial fibrillation. Heart Rhythm 7:149\u2013154","journal-title":"Heart Rhythm"},{"key":"2786_CR40","doi-asserted-by":"publisher","first-page":"1931","DOI":"10.1016\/j.jacc.2019.01.056","volume":"73","author":"CG Santos-Gallego","year":"2019","unstructured":"Santos-Gallego CG, Requena-Ibanez JA, San Antonio R, Ishikawa K, Watanabe S, Picatoste B, Flores E, Garcia-Ropero A, Sanz J, Hajjar RJ, Fuster V, Badimon JJ (2019) Empagliflozin ameliorates adverse left ventricular remodeling in nondiabetic heart failure by enhancing myocardial energetics. J Am Coll Cardiol 73:1931\u20131944","journal-title":"J Am Coll Cardiol"},{"key":"2786_CR41","doi-asserted-by":"publisher","first-page":"230","DOI":"10.1038\/nrcardio.2015.2","volume":"12","author":"Y-F Hu","year":"2015","unstructured":"Hu Y-F, Chen Y-J, Lin Y-J, Chen S-A (2015) Inflammation and the pathogenesis of atrial fibrillation. Nat Rev Cardiol 12:230\u2013243","journal-title":"Nat Rev Cardiol"}],"container-title":["Clinical Research in Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00392-025-02786-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00392-025-02786-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00392-025-02786-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T07:52:22Z","timestamp":1763625142000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00392-025-02786-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,20]]},"references-count":41,"alternative-id":["2786"],"URL":"https:\/\/doi.org\/10.1007\/s00392-025-02786-2","relation":{},"ISSN":["1861-0684","1861-0692"],"issn-type":[{"value":"1861-0684","type":"print"},{"value":"1861-0692","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,20]]},"assertion":[{"value":"7 September 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 October 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 November 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Our study is a subproject of clinical research with the clinical trial number of NCT06363604. The study was conducted in accordance with the Declaration of Helsinki, and the protocol was approved by the Ethics Committee of Xinhua Hospital, with the ethical approval number XHEC-C-2023\u2013128-2.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Written informed consent for publication was obtained from all participants.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}