{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T03:07:35Z","timestamp":1768532855634,"version":"3.49.0"},"reference-count":46,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T00:00:00Z","timestamp":1768176000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T00:00:00Z","timestamp":1768176000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Res Cardiol"],"DOI":"10.1007\/s00392-025-02835-w","type":"journal-article","created":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T10:38:37Z","timestamp":1768214317000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Optimal timing of anticoagulation after ischemic stroke in atrial fibrillation: a systematic review and network meta-analysis"],"prefix":"10.1007","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-5894-7714","authenticated-orcid":false,"given":"Julia","family":"M. Fernandes","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric","family":"Katsuyama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"K. Fukunaga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Carolina","family":"Covre Coan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wilson","family":"Falco Neto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoana","family":"Palatianos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iuri","family":"Ferreira Felix","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alonzo","family":"Armani Prata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriel","family":"Scarpioni Barbosa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luciana","family":"Gioli-Pereira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ronaldo","family":"C. Filho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andr\u00e9","family":"d\u2019Avila","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,1,12]]},"reference":[{"key":"2835_CR1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2024.22451","author":"D Ko","year":"2025","unstructured":"Ko D, Chung MK, Evans PT, Benjamin EJ, Helm RH (2025) Atrial fibrillation: a review. JAMA. https:\/\/doi.org\/10.1001\/jama.2024.22451","journal-title":"JAMA"},{"key":"2835_CR2","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1016\/j.ahj.2015.10.021","volume":"173","author":"OJ Ziff","year":"2016","unstructured":"Ziff OJ, Camm AJ (2016) Individualized approaches to thromboprophylaxis in atrial fibrillation. Am Heart J 173:143\u2013158. https:\/\/doi.org\/10.1016\/j.ahj.2015.10.021","journal-title":"Am Heart J"},{"key":"2835_CR3","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp2023658","author":"GF Michaud","year":"2021","unstructured":"Michaud GF, Stevenson WG (2021) Atrial fibrillation. N Engl J Med. https:\/\/doi.org\/10.1056\/NEJMcp2023658","journal-title":"N Engl J Med"},{"key":"2835_CR4","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1177\/2396987318787124","volume":"3","author":"D Munn","year":"2018","unstructured":"Munn D, Abdul-Rahim AH, Fischer U, Werring DJ, Robinson TG, Dawson J (2018) A survey of opinion: when to start oral anticoagulants in patients with acute ischaemic stroke and atrial fibrillation? Eur Stroke J 3:355\u2013360","journal-title":"Eur Stroke J"},{"key":"2835_CR5","doi-asserted-by":"publisher","unstructured":"Connolly SJ, Ezekowitz MD, Yusuf S, RE-LY Steering Committee and Investigators et al (2009) Dabigatran versus warfarin in patients with atrial fibrillation. N Engl J Med 361(17):1139\u201351. https:\/\/doi.org\/10.1056\/NEJMoa0905561","DOI":"10.1056\/NEJMoa0905561"},{"key":"2835_CR6","doi-asserted-by":"publisher","unstructured":"Patel MR, Mahaffey KW, Garg J, ROCKET AF Investigators et al (2011) Rivaroxaban versus warfarin in nonvalvular atrial fibrillation. N Engl J Med 365(8):883\u201391. https:\/\/doi.org\/10.1056\/NEJMoa1009638","DOI":"10.1056\/NEJMoa1009638"},{"issue":"7","key":"2835_CR7","doi-asserted-by":"publisher","first-page":"e364","DOI":"10.1161\/STR.0000000000000375","volume":"52","author":"DO Kleindorfer","year":"2021","unstructured":"Kleindorfer DO, Towfighi A, Chaturvedi S et al (2021) 2021 guideline for the prevention of stroke in patients with stroke and transient ischemic attack: a guideline from the American Heart Association\/American Stroke Association. Stroke 52(7):e364\u2013e467. https:\/\/doi.org\/10.1161\/STR.0000000000000375","journal-title":"Stroke"},{"key":"2835_CR8","doi-asserted-by":"publisher","first-page":"2094","DOI":"10.1093\/eurheartj\/eht134","volume":"34","author":"H Heidbuchel","year":"2013","unstructured":"Heidbuchel H, Verhamme P, Alings M et al (2013) EHRA practical guide on the use of new oral anticoagulants in patients with non-valvular atrial fibrillation: executive summary. Eur Heart J 34:2094\u2013106","journal-title":"Eur Heart J"},{"key":"2835_CR9","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(25)00439-8","author":"HM Dehbi","year":"2025","unstructured":"Dehbi HM, Fischer U, \u00c5sberg S et al (2025) Collaboration on the optimal timing of anticoagulation after ischaemic stroke and atrial fibrillation: a systematic review and prospective individual participant data meta-analysis of randomised controlled trials (CATALYST). Lancet. https:\/\/doi.org\/10.1016\/S0140-6736(25)00439-8","journal-title":"Lancet"},{"key":"2835_CR10","doi-asserted-by":"publisher","unstructured":"Fischer U, Koga M, Strbian D, ELAN Investigators et al (2023) Early versus later anticoagulation for stroke with atrial fibrillation. N Engl J Med 388(29):2411\u20132421. https:\/\/doi.org\/10.1056\/NEJMoa2303048","DOI":"10.1056\/NEJMoa2303048"},{"issue":"14","key":"2835_CR11","doi-asserted-by":"publisher","first-page":"1056","DOI":"10.1161\/CIRCULATIONAHA.122.060666","volume":"4","author":"J Oldgren","year":"2022","unstructured":"Oldgren J, \u00c5sberg S, Hijazi Z, Wester P, Bertilsson M, Norrving B (2022) Early versus delayed non-vitamin K antagonist oral anticoagulant therapy after acute ischemic stroke in atriaL FIBRILLATION (TIMING): a registry-based randomized controlled noninferiority study. Circulation 4(14):1056\u20131066. https:\/\/doi.org\/10.1161\/CIRCULATIONAHA.122.060666","journal-title":"Circulation"},{"key":"2835_CR12","doi-asserted-by":"publisher","unstructured":"Werring DJ, Dehbi HM, Ahmed N, OPTIMAS investigators et al (2024) Optimal timing of anticoagulation after acute ischaemic stroke with atrial fibrillation (OPTIMAS): a multicentre, blinded-endpoint, phase 4, randomised controlled trial. Lancet. https:\/\/doi.org\/10.1016\/S0140-6736(24)02197-4","DOI":"10.1016\/S0140-6736(24)02197-4"},{"key":"2835_CR13","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2025.0285","author":"SJ Warach","year":"2025","unstructured":"Warach SJ, Davis LA, Lawrence P et al (2025) Optimal delay time to initiate anticoagulation after ischemic stroke in atrial fibrillation: a pragmatic, response-adaptive randomized clinical trial. JAMA Neurol. https:\/\/doi.org\/10.1001\/jamaneurol.2025.0285","journal-title":"JAMA Neurol"},{"issue":"4","key":"2835_CR14","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1007\/s40265-023-01837-0","volume":"83","author":"VKC Yan","year":"2023","unstructured":"Yan VKC, Li HL, Wei L, Knapp MRJ, Wong ICK, Chan EW (2023) Evolving trends in consumption of direct oral anticoagulants in 65 countries\/regions from 2008 to 2019. Drugs 83(4):315\u2013340. https:\/\/doi.org\/10.1007\/s40265-023-01837-0","journal-title":"Drugs"},{"key":"2835_CR15","doi-asserted-by":"publisher","unstructured":"BMJ (Open Access) Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD et al (2021) The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ 372:n71. https:\/\/doi.org\/10.1136\/bmj.n71","DOI":"10.1136\/bmj.n71"},{"key":"2835_CR16","unstructured":"Higgins JPT, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, Welch VA (editors) (2023) Cochrane handbook for systematic reviews of interventions version 6.5 (updated August 2024). Cochrane, 2024. Available from www.cochrane.org\/handbook"},{"key":"2835_CR17","doi-asserted-by":"publisher","DOI":"10.1001\/jamasurg.2021.0522","author":"BS Brooke","year":"2021","unstructured":"Brooke BS, Schwartz TA, Pawlik TM (2021) MOOSE reporting guidelines for meta-analyses of observational studies. JAMA Surg. https:\/\/doi.org\/10.1001\/jamasurg.2021.0522","journal-title":"JAMA Surg"},{"key":"2835_CR18","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.l4898","volume":"366","author":"JAC Sterne","year":"2019","unstructured":"Sterne JAC, Savovic J, Page MJ et al (2019) RoB 2: a revised tool for assessing risk of bias in rando- mised trials. BMJ 366:l4898. https:\/\/doi.org\/10.1136\/bmj.l4898","journal-title":"BMJ"},{"issue":"355","key":"2835_CR19","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.i4919","volume":"12","author":"JA Sterne","year":"2016","unstructured":"Sterne JA, Hern\u00e1n MA, Reeves BC, Savovi\u0107 J, Berkman ND, Viswanathan M et al (2016Oct) ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions. BMJ 12(355):i4919","journal-title":"BMJ"},{"key":"2835_CR20","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.d4002","volume":"343","author":"JA Sterne","year":"2011","unstructured":"Sterne JA, Sutton AJ, Ioannidis JP et al (2011) Recommendations for examining and interpreting funnel plot asymmetry in meta-analyses of randomised controlled trials. BMJ 343:d4002. https:\/\/doi.org\/10.1136\/bmj.d4002","journal-title":"BMJ"},{"key":"2835_CR21","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2019.116582","volume":"409","author":"AI Al Bakr","year":"2020","unstructured":"Al Bakr AI, AlOmar RS, Nada MAF et al (2020) Timing to start anticoagulants after acute ischemic stroke with non-valvular atrial fibrillation. J Neurol Sci 409:116582. https:\/\/doi.org\/10.1016\/j.jns.2019.116582","journal-title":"J Neurol Sci"},{"issue":"8","key":"2835_CR22","doi-asserted-by":"publisher","first-page":"2821","DOI":"10.1007\/s10072-023-06717-9","volume":"44","author":"M Cappellari","year":"2023","unstructured":"Cappellari M, Emiliani A, Zivelonghi C, Micheletti N, Tomelleri G, Bonetti B (2023) Application of the \u201c1-2-3-4-day\u201d rule to stroke severity at baseline versus at 24 h to start direct oral anticoagulant for atrial fibrillation within 7 days from symptom onset. Neurol Sci 44(8):2821\u20132829. https:\/\/doi.org\/10.1007\/s10072-023-06717-9","journal-title":"Neurol Sci"},{"issue":"6","key":"2835_CR23","doi-asserted-by":"publisher","first-page":"939","DOI":"10.1055\/a-1669-4987","volume":"122","author":"PY Chang","year":"2022","unstructured":"Chang PY, Wang WT, Wu WL et al (2022) Oral anticoagulation timing in patients with acute ischemic stroke and atrial fibrillation. Thromb Haemost 122(6):939\u2013950. https:\/\/doi.org\/10.1055\/a-1669-4987","journal-title":"Thromb Haemost"},{"issue":"2","key":"2835_CR24","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1136\/jnnp-2021-327236","volume":"93","author":"GM De Marchis","year":"2022","unstructured":"De Marchis GM, Seiffge DJ, Schaedelin S et al (2022) Early versus late start of direct oral anticoagulants after acute ischaemic stroke linked to atrial fibrillation: an observational study and individual patient data pooled analysis. J Neurol Neurosurg Psychiatry 93(2):119\u2013125. https:\/\/doi.org\/10.1136\/jnnp-2021-327236","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"2835_CR25","doi-asserted-by":"publisher","unstructured":"Grosse GM, H\u00fcsing A, Stang A, PRODAST Investigators et al (2023) Early or late initiation of dabigatran versus vitamin-K-antagonists in acute ischemic stroke or TIA: the PRODAST study. Int J Stroke 18(10):1169\u20131177. https:\/\/doi.org\/10.1177\/17474930231184366","DOI":"10.1177\/17474930231184366"},{"issue":"5","key":"2835_CR26","doi-asserted-by":"publisher","first-page":"1540","DOI":"10.1161\/STROKEAHA.121.036695","volume":"53","author":"S Kimura","year":"2022","unstructured":"Kimura S, Toyoda K, Yoshimura S et al (2022) Practical \u201c1-2-3-4-day\u201d rule for starting direct oral anticoagulants after ischemic stroke with atrial fibrillation: combined hospital-based cohort study. Stroke 53(5):1540\u20131549. https:\/\/doi.org\/10.1161\/STROKEAHA.121.036695","journal-title":"Stroke"},{"issue":"4","key":"2835_CR27","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0264760","volume":"17","author":"J Koge","year":"2022","unstructured":"Koge J, Yamagami H, Toyoda K et al (2022) Early initiation of rivaroxaban after reperfusion therapy for stroke patients with nonvalvular atrial fibrillation. PLoS One 17(4):e0264760. https:\/\/doi.org\/10.1371\/journal.pone.0264760","journal-title":"PLoS One"},{"issue":"4","key":"2835_CR28","doi-asserted-by":"publisher","first-page":"2099","DOI":"10.1007\/s00415-021-10788-z","volume":"269","author":"J Matos-Ribeiro","year":"2022","unstructured":"Matos-Ribeiro J, Castro-Chaves P, Oliveira-Ferreira M, Fonseca L, Pintalhao M (2022) Early anticoagulation in atrial fibrillation-related acute ischaemic stroke: efficacy and safety profile. J Neurol 269(4):2099\u20132112. https:\/\/doi.org\/10.1007\/s00415-021-10788-z","journal-title":"J Neurol"},{"issue":"3","key":"2835_CR29","doi-asserted-by":"publisher","first-page":"883","DOI":"10.1161\/STROKEAHA.119.028118","volume":"51","author":"T Mizoguchi","year":"2020","unstructured":"Mizoguchi T, Tanaka K, Toyoda K et al (2020) Early initiation of direct oral anticoagulants after onset of stroke and short- and long-term outcomes of patients with nonvalvular atrial fibrillation. Stroke 51(3):883\u2013891. https:\/\/doi.org\/10.1161\/STROKEAHA.119.028118","journal-title":"Stroke"},{"issue":"2","key":"2835_CR30","doi-asserted-by":"publisher","DOI":"10.1136\/openhrt-2024-002688","volume":"11","author":"MC Olma","year":"2024","unstructured":"Olma MC, T\u00fct\u00fcnc\u00fc S, Hansen K et al (2024) Timing of oral anticoagulation in atrial fibrillation patients after acute ischaemic stroke and outcome after 3 months: results of the multicentre Berlin Atrial Fibrillation Registry. Open Heart 11(2):e002688. https:\/\/doi.org\/10.1136\/openhrt-2024-002688","journal-title":"Open Heart"},{"issue":"4","key":"2835_CR31","doi-asserted-by":"publisher","first-page":"374","DOI":"10.1177\/2396987320937116","volume":"5","author":"M Paciaroni","year":"2020","unstructured":"Paciaroni M, Agnelli G, Giustozzi M et al (2020) Timing of initiation of oral anticoagulants in patients with acute ischemic stroke and atrial fibrillation comparing posterior and anterior circulation strokes. Eur Stroke J 5(4):374\u2013383. https:\/\/doi.org\/10.1177\/2396987320937116","journal-title":"Eur Stroke J"},{"issue":"18","key":"2835_CR32","doi-asserted-by":"publisher","first-page":"1856","DOI":"10.1212\/WNL.0000000000003283","volume":"87","author":"DJ Seiffge","year":"2016","unstructured":"Seiffge DJ, Traenka C, Polymeris A et al (2016) Early start of DOAC after ischemic stroke: risk of intracranial hemorrhage and recurrent events. Neurology 87(18):1856\u20131862. https:\/\/doi.org\/10.1212\/WNL.0000000000003283","journal-title":"Neurology"},{"issue":"1","key":"2835_CR33","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1136\/svn-2023-002357","volume":"9","author":"A Sharobeam","year":"2024","unstructured":"Sharobeam A, Lin L, Lam C et al (2024) Early anticoagulation in patients with stroke and atrial fibrillation is associated with fewer ischaemic lesions at 1 month: the ATTUNE study. Stroke Vasc Neurol 9(1):30\u201337. https:\/\/doi.org\/10.1136\/svn-2023-002357","journal-title":"Stroke Vasc Neurol"},{"issue":"4","key":"2835_CR34","doi-asserted-by":"publisher","first-page":"807","DOI":"10.1002\/ana.25844","volume":"88","author":"S Yaghi","year":"2020","unstructured":"Yaghi S, Trivedi T, Henninger N et al (2020) Anticoagulation timing in cardioembolic stroke and recurrent event risk. Ann Neurol 88(4):807\u2013816. https:\/\/doi.org\/10.1002\/ana.25844","journal-title":"Ann Neurol"},{"issue":"2","key":"2835_CR35","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0212354","volume":"14","author":"M Yasaka","year":"2019","unstructured":"Yasaka M, Minematsu K, Toyoda K et al (2019) Rivaroxaban administration after acute ischemic stroke: the RELAXED study. PLoS One 14(2):e0212354. https:\/\/doi.org\/10.1371\/journal.pone.0212354","journal-title":"PLoS One"},{"issue":"4","key":"2835_CR36","doi-asserted-by":"publisher","first-page":"692","DOI":"10.1007\/s12975-020-00871-4","volume":"12","author":"S Yoshimura","year":"2021","unstructured":"Yoshimura S, Uchida K, Sakai N et al (2021) Correction to: Safety of early administration of apixaban on clinical outcomes in patients with acute large vessel occlusion. Transl Stroke Res 12(4):692\u2013694. https:\/\/doi.org\/10.1007\/s12975-020-00871-4","journal-title":"Transl Stroke Res"},{"issue":"4","key":"2835_CR37","doi-asserted-by":"publisher","first-page":"613","DOI":"10.1007\/s11239-023-02928-1","volume":"57","author":"JC Mwita","year":"2024","unstructured":"Mwita JC, Francis JM, Pillay C, Ogah OS, Goshu DY, Agyekum F, Musonda JM, James MC, Tefera E, Kabo T, Ditlhabolo KI, Ndlovu K, Ayodele AY, Mikomangwa WP, Chillo P, Damasceno A, Folson AA, Oyekunle A, Tebuka E, Kalokola F, Forrest K, Dunn H, Karaye K, Jean-Pierre FL, Oljira CF, Assefa T, Taiwo TS, Nwafor CE, Omole O, Anakwue R, Cohen K (2024) Anticoagulation control among patients on vitamin K antagonists in nine countries in sub-Saharan Africa. J Thromb Thrombolysis 57(4):613\u2013621. https:\/\/doi.org\/10.1007\/s11239-023-02928-1","journal-title":"J Thromb Thrombolysis"},{"issue":"12","key":"2835_CR38","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3026(24)00281-3","volume":"11","author":"W Ageno","year":"2024","unstructured":"Ageno W, Caramelli B, Donadini MP, Girardi L, Riva N (2024) Changes in the landscape of anticoagulation: a focus on direct oral anticoagulants. Lancet Haematol 11(12):e938-e950. https:\/\/doi.org\/10.1016\/S2352-3026(24)00281-3","journal-title":"Lancet Haematol"},{"key":"2835_CR39","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1016\/j.ijcard.2016.08.236","volume":"223","author":"S Oh","year":"2016","unstructured":"Oh S, Goto S, Accetta G, Angchaisuksiri P, Camm AJ, Cools F, Haas S, Kayani G, Koretsune Y, Lim TW, Misselwitz F, van Eickels M, Kakkar AK (2016) Vitamin K antagonist control in patients with atrial fibrillation in Asia compared with other regions of the world: Real-world data from the GARFIELD-AF registry. Int J Cardiol 223:543\u2013547. https:\/\/doi.org\/10.1016\/j.ijcard.2016.08.236","journal-title":"Int J Cardiol"},{"issue":"7","key":"2835_CR40","doi-asserted-by":"publisher","first-page":"693","DOI":"10.1001\/jamaneurol.2024.1450","volume":"81","author":"MB Goeldlin","year":"2024","unstructured":"Goeldlin MB, Hakim A, Branca M et al (2024) Early vs late anticoagulation in minor, moderate, and major ischemic stroke with atrial fibrillation: post hoc analysis of the ELAN randomized clinical trial. JAMA Neurol 81(7):693\u2013702. https:\/\/doi.org\/10.1001\/jamaneurol.2024.1450","journal-title":"JAMA Neurol"},{"issue":"4","key":"2835_CR41","doi-asserted-by":"publisher","first-page":"885","DOI":"10.1177\/23969873241251931","volume":"9","author":"L Palaiodimou","year":"2024","unstructured":"Palaiodimou L, Stefanou MI, Katsanos AH et al (2024) Timing of oral anticoagulants initiation for atrial fibrillation after acute ischemic stroke: a systematic review and meta-analysis. Eur Stroke J 9(4):885\u2013895. https:\/\/doi.org\/10.1177\/23969873241251931","journal-title":"Eur Stroke J"},{"key":"2835_CR42","doi-asserted-by":"publisher","unstructured":"Fu L, Hu J, Yang P, Chen Q (2024 Dec 11) Early vs later non-vitamin K antagonist oral anticoagulants in patients with acute ischemic stroke and atrial fibrillation: a meta-analysis and systematic review of randomized trials. Heart Rhythm S1547\u20135271(24)03646\u20134. https:\/\/doi.org\/10.1016\/j.hrthm.2024.12.008. Epub ahead of print. PMID: 39672479.","DOI":"10.1016\/j.hrthm.2024.12.008"},{"issue":"1","key":"2835_CR43","doi-asserted-by":"publisher","DOI":"10.1016\/j.jstrokecerebrovasdis.2024.108159","volume":"34","author":"OM Al-Janabi","year":"2025","unstructured":"Al-Janabi OM, Odeh A, Gajjar A et al (2025) Timing of anticoagulation for patients with atrial fibrillation after acute ischemic stroke: systematic review and meta-analysis. J Stroke Cerebrovasc Dis 34(1):108159. https:\/\/doi.org\/10.1016\/j.jstrokecerebrovasdis.2024.108159","journal-title":"J Stroke Cerebrovasc Dis"},{"issue":"2","key":"2835_CR44","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1161\/01.STR.0000254622.52483.03","volume":"38","author":"KK Andersen","year":"2007","unstructured":"Andersen KK, Olsen TS (2007) Reduced poststroke mortality in patients with stroke and atrial fibrillation treated with anticoagulants: results from a Danish quality-control registry of 22,179 patients with ischemic stroke. Stroke 38(2):259\u2013263. https:\/\/doi.org\/10.1161\/01.STR.0000254622.52483.03","journal-title":"Stroke"},{"issue":"5","key":"2835_CR45","doi-asserted-by":"publisher","first-page":"e198","DOI":"10.1161\/STR.0000000000000358","volume":"52","author":"MaryL Rodgers","year":"2021","unstructured":"Rodgers Mary L et al (2021) Care of the patient with acute ischemic stroke (endovascular\/intensive care Unit-postinterventional therapy): update to 2009 comprehensive nursing care scientific statement: a scientific statement from the American Heart Association. Stroke 52(5):e198\u2013e210. https:\/\/doi.org\/10.1161\/STR.0000000000000358","journal-title":"Stroke"},{"issue":"2","key":"2835_CR46","doi-asserted-by":"publisher","DOI":"10.1136\/openhrt-2024-003002","volume":"11","author":"A Dilli Babu","year":"2024","unstructured":"Dilli Babu A, Singh S, Gorantla A et al (2024) Optimal timing of oral anticoagulation initiation in patients with acute ischaemic stroke and atrial fibrillation: a comprehensive meta-analysis and systematic review. Open Heart 11(2):e003002. https:\/\/doi.org\/10.1136\/openhrt-2024-003002","journal-title":"Open Heart"}],"container-title":["Clinical Research in Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00392-025-02835-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00392-025-02835-w","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00392-025-02835-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T10:31:18Z","timestamp":1768473078000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00392-025-02835-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,12]]},"references-count":46,"alternative-id":["2835"],"URL":"https:\/\/doi.org\/10.1007\/s00392-025-02835-w","relation":{},"ISSN":["1861-0684","1861-0692"],"issn-type":[{"value":"1861-0684","type":"print"},{"value":"1861-0692","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,12]]},"assertion":[{"value":"11 August 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 December 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 January 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"All authors report no relationships that could be construed as a conflict of interest. All authors take responsibility for all aspects of the reliability and freedom from bias of the data presented and their discussed interpretation.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}}]}}