{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T16:08:21Z","timestamp":1780416501418,"version":"3.54.1"},"reference-count":35,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T00:00:00Z","timestamp":1780358400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T00:00:00Z","timestamp":1780358400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Res Cardiol"],"DOI":"10.1007\/s00392-026-02948-w","type":"journal-article","created":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T15:36:05Z","timestamp":1780414565000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Invasive transvalvular flow rate to predict likely severe aortic valve stenosis with low-gradient and normal ejection fraction"],"prefix":"10.1007","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4763-4874","authenticated-orcid":false,"given":"Karim","family":"Elbasha","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arief","family":"Kurniadi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed","family":"Samy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Landt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sultan","family":"Alotaibi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marwa","family":"Zakaria","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ralph","family":"Toelg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Holger","family":"Nef","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gert","family":"Richardt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nader","family":"Mankerious","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdelhakim","family":"Allali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,6,2]]},"reference":[{"key":"2948_CR1","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1016\/j.amjcard.2021.09.046","volume":"163","author":"G Vavilis","year":"2022","unstructured":"Vavilis G, Back M, Barany P, Szummer K (2022) Epidemiology of aortic stenosis\/aortic valve replacement (from the Nationwide Swedish Renal Registry). Am J Cardiol 163:58\u201364","journal-title":"Am J Cardiol"},{"key":"2948_CR2","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1016\/j.jacc.2023.04.049","volume":"82","author":"MV Madhavan","year":"2023","unstructured":"Madhavan MV, Kodali SK, Thourani VH, Makkar R, Mack MJ, Kapadia S, Webb JG, Cohen DJ, Herrmann HC, Williams M, Greason K, Pibarot P, Hahn RT, Jaber W, Xu K, Alu M, Smith CR, Leon MB (2023) Outcomes of SAPIEN 3 transcatheter aortic valve replacement compared with surgical valve replacement in intermediate-risk patients. J Am Coll Cardiol 82:109\u2013123","journal-title":"J Am Coll Cardiol"},{"key":"2948_CR3","doi-asserted-by":"publisher","first-page":"2187","DOI":"10.1056\/NEJMoa1103510","volume":"364","author":"CR Smith","year":"2011","unstructured":"Smith CR, Leon MB, Mack MJ, Miller DC, Moses JW, Svensson LG, Tuzcu EM, Webb JG, Fontana GP, Makkar RR, Williams M, Dewey T, Kapadia S, Babaliaros V, Thourani VH, Corso P, Pichard AD, Bavaria JE, Herrmann HC, Akin JJ, Anderson WN, Wang D, Pocock SJ, Investigators PT (2011) Transcatheter versus surgical aortic-valve replacement in high-risk patients. N Engl J Med 364:2187\u201398","journal-title":"N Engl J Med"},{"key":"2948_CR4","doi-asserted-by":"publisher","first-page":"1202","DOI":"10.1016\/j.amjcard.2020.01.015","volume":"125","author":"P Tzamalis","year":"2020","unstructured":"Tzamalis P, Alataki S, Bramlage P, Schmitt C, Schymik G (2020) Comparison of valve durability and outcomes of transcatheter aortic valve implantation versus surgical aortic valve replacement in patients with severe symptomatic aortic stenosis and less-than-high-risk for surgery. Am J Cardiol 125:1202\u20131208","journal-title":"Am J Cardiol"},{"key":"2948_CR5","doi-asserted-by":"publisher","first-page":"1000","DOI":"10.1001\/jamacardio.2022.2695","volume":"7","author":"NM Van Mieghem","year":"2022","unstructured":"Van Mieghem NM, Deeb GM, Sondergaard L, Grube E, Windecker S, Gada H, Mumtaz M, Olsen PS, Heiser JC, Merhi W, Kleiman NS, Chetcuti SJ, Gleason TG, Lee JS, Cheng W, Makkar RR, Crestanello J, George B, George I, Kodali S, Yakubov SJ, Serruys PW, Lange R, Piazza N, Williams MR, Oh JK, Adams DH, Li S, Reardon MJ, Investigators ST (2022) Self-expanding transcatheter vs surgical aortic valve replacement in intermediate-risk patients: 5-year outcomes of the SURTAVI randomized clinical trial. JAMA Cardiol 7:1000\u20131008","journal-title":"JAMA Cardiol"},{"key":"2948_CR6","doi-asserted-by":"publisher","unstructured":"Paolisso P, Ausiello D, Cefali F, Policastro P, Vincelli G, Militello C, Vannini F, Rubino I, Gallinoro E, Belmonte M, Berni A, Casenghi M, Barbato E (2025) Evolving indications for transcatheter aortic valve implantation: key issues from procedural challenges to lifetime management. Can J Cardiol. https:\/\/doi.org\/10.1016\/j.cjca.2025.12.006","DOI":"10.1016\/j.cjca.2025.12.006"},{"key":"2948_CR7","doi-asserted-by":"publisher","first-page":"4635","DOI":"10.1093\/eurheartj\/ehaf194","volume":"46","author":"F Praz","year":"2025","unstructured":"Praz F, Borger MA, Lanz J, Marin-Cuartas M, Abreu A, Adamo M, Ajmone Marsan N, Barili F, Bonaros N, Cosyns B, De Paulis R, Gamra H, Jahangiri M, Jeppsson A, Klautz RJM, Mores B, Perez-David E, Poss J, Prendergast BD, Rocca B, Rossello X, Suzuki M, Thiele H, Tribouilloy CM, Wojakowski W, Group EESD (2025) 2025 ESC\/EACTS guidelines for the management of valvular heart disease. Eur Heart J 46:4635\u20134736","journal-title":"Eur Heart J"},{"key":"2948_CR8","doi-asserted-by":"publisher","first-page":"1758","DOI":"10.1016\/j.jacc.2020.02.046","volume":"75","author":"M Namasivayam","year":"2020","unstructured":"Namasivayam M, He W, Churchill TW, Capoulade R, Liu S, Lee H, Danik JS, Picard MH, Pibarot P, Levine RA, Hung J (2020) Transvalvular flow rate determines prognostic value of aortic valve area in aortic stenosis. J Am Coll Cardiol 75:1758\u20131769","journal-title":"J Am Coll Cardiol"},{"key":"2948_CR9","doi-asserted-by":"publisher","first-page":"727","DOI":"10.1093\/ejcts\/ezab389","volume":"60","author":"A Vahanian","year":"2021","unstructured":"Vahanian A, Beyersdorf F, Praz F, Milojevic M, Baldus S, Bauersachs J, Capodanno D, Conradi L, De Bonis M, De Paulis R, Delgado V, Freemantle N, Gilard M, Haugaa KH, Jeppsson A, Juni P, Pierard L, Prendergast BD, Sadaba JR, Tribouilloy C, Wojakowski W, Group EESD (2021) 2021 ESC\/EACTS guidelines for the management of valvular heart disease. Eur J Cardiothorac Surg 60:727\u2013800","journal-title":"Eur J Cardiothorac Surg"},{"key":"2948_CR10","doi-asserted-by":"publisher","first-page":"1102","DOI":"10.1093\/ehjci\/jez211","volume":"20","author":"E Guzzetti","year":"2019","unstructured":"Guzzetti E, Pibarot P, Clavel MA (2019) Normal-flow low-gradient severe aortic stenosis is a frequent and real entity. Eur Heart J Cardiovasc Imaging 20:1102\u20131104","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"2948_CR11","doi-asserted-by":"publisher","first-page":"797","DOI":"10.1016\/j.jcmg.2015.09.026","volume":"9","author":"M Berthelot-Richer","year":"2016","unstructured":"Berthelot-Richer M, Pibarot P, Capoulade R, Dumesnil JG, Dahou A, Thebault C, Le Ven F, Clavel MA (2016) Discordant grading of aortic stenosis severity: echocardiographic predictors of survival benefit associated with aortic valve replacement. JACC Cardiovasc Imaging 9:797\u2013805","journal-title":"JACC Cardiovasc Imaging"},{"key":"2948_CR12","doi-asserted-by":"publisher","first-page":"1463","DOI":"10.1136\/hrt.2009.181982","volume":"96","author":"J Minners","year":"2010","unstructured":"Minners J, Allgeier M, Gohlke-Baerwolf C, Kienzle RP, Neumann FJ, Jander N (2010) Inconsistent grading of aortic valve stenosis by current guidelines: haemodynamic studies in patients with apparently normal left ventricular function. Heart 96:1463\u20131468","journal-title":"Heart"},{"key":"2948_CR13","doi-asserted-by":"publisher","first-page":"2739","DOI":"10.1093\/eurheartj\/ehx391","volume":"38","author":"H Baumgartner","year":"2017","unstructured":"Baumgartner H, Falk V, Bax JJ, De Bonis M, Hamm C, Holm PJ, Iung B, Lancellotti P, Lansac E, Rodriguez Munoz D, Rosenhek R, Sjogren J, Tornos Mas P, Vahanian A, Walther T, Wendler O, Windecker S, Zamorano JL, Group ESCSD (2017) 2017 ESC\/EACTS guidelines for the management of valvular heart disease. Eur Heart J 38:2739\u20132791","journal-title":"Eur Heart J"},{"key":"2948_CR14","doi-asserted-by":"publisher","first-page":"782","DOI":"10.1016\/j.jacc.2013.05.044","volume":"62","author":"F Le Ven","year":"2013","unstructured":"Le Ven F, Freeman M, Webb J, Clavel MA, Wheeler M, Dumont E, Thompson C, De Larochelliere R, Moss R, Doyle D, Ribeiro HB, Urena M, Nombela-Franco L, Rodes-Cabau J, Pibarot P (2013) Impact of low flow on the outcome of high-risk patients undergoing transcatheter aortic valve replacement. J Am Coll Cardiol 62:782\u2013788","journal-title":"J Am Coll Cardiol"},{"key":"2948_CR15","doi-asserted-by":"publisher","first-page":"1992","DOI":"10.1093\/eurheartj\/ehy123","volume":"39","author":"D Rusinaru","year":"2018","unstructured":"Rusinaru D, Bohbot Y, Ringle A, Marechaux S, Diouf M, Tribouilloy C (2018) Impact of low stroke volume on mortality in patients with severe aortic stenosis and preserved left ventricular ejection fraction. Eur Heart J 39:1992\u20131999","journal-title":"Eur Heart J"},{"key":"2948_CR16","doi-asserted-by":"crossref","unstructured":"Mangner N, Stachel G, Woitek F, Haussig S, Schlotter F, Hollriegel R, Adam J, Lindner A, Mohr FW, Schuler G, Kiefer P, Leontyev S, Borger MA, Thiele H, Holzhey D, Linke (2018) A Predictors of mortality and symptomatic outcome of patients with low-flow severe aortic stenosis undergoing transcatheter aortic valve replacement. J Am Heart Assoc 7","DOI":"10.1161\/JAHA.117.007977"},{"key":"2948_CR17","doi-asserted-by":"publisher","first-page":"1715","DOI":"10.1016\/j.jcmg.2018.01.011","volume":"12","author":"A Vamvakidou","year":"2019","unstructured":"Vamvakidou A, Jin W, Danylenko O, Chahal N, Khattar R, Senior R (2019) Low transvalvular flow rate predicts mortality in patients with low-gradient aortic stenosis following aortic valve intervention. JACC Cardiovasc Imaging 12:1715\u20131724","journal-title":"JACC Cardiovasc Imaging"},{"issue":"1\u201339","key":"2948_CR18","first-page":"e14","volume":"28","author":"RM Lang","year":"2015","unstructured":"Lang RM, Badano LP, Mor-Avi V, Afilalo J, Armstrong A, Ernande L, Flachskampf FA, Foster E, Goldstein SA, Kuznetsova T, Lancellotti P, Muraru D, Picard MH, Rietzschel ER, Rudski L, Spencer KT, Tsang W, Voigt JU (2015) Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American society of echocardiography and the European association of cardiovascular imaging. J Am Soc Echocardiogr 28(1\u201339):e14","journal-title":"J Am Soc Echocardiogr"},{"key":"2948_CR19","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1016\/j.carrev.2022.03.019","volume":"39","author":"MM Ansari","year":"2022","unstructured":"Ansari MM, Del Rio-Pertuz G (2022) Normal-flow, low-gradient aortic stenosis: is it truly a severe aortic stenosis that merits TAVI? Cardiovasc Revasc Med 39:18\u201319","journal-title":"Cardiovasc Revasc Med"},{"key":"2948_CR20","doi-asserted-by":"publisher","first-page":"372","DOI":"10.1016\/j.echo.2017.02.009","volume":"30","author":"H Baumgartner","year":"2017","unstructured":"Baumgartner H, Hung J, Bermejo J, Chambers JB, Edvardsen T, Goldstein S, Lancellotti P, LeFevre M, Miller F Jr, Otto CM (2017) Recommendations on the echocardiographic assessment of aortic valve stenosis: a focused update from the European association of cardiovascular imaging and the American society of echocardiography. J Am Soc Echocardiogr 30:372\u2013392","journal-title":"J Am Soc Echocardiogr"},{"key":"2948_CR21","doi-asserted-by":"publisher","first-page":"1906","DOI":"10.1093\/eurheartj\/eht094","volume":"34","author":"P Mehrotra","year":"2013","unstructured":"Mehrotra P, Jansen K, Flynn AW, Tan TC, Elmariah S, Picard MH, Hung J (2013) Differential left ventricular remodelling and longitudinal function distinguishes low flow from normal-flow preserved ejection fraction low-gradient severe aortic stenosis. Eur Heart J 34:1906\u20131914","journal-title":"Eur Heart J"},{"key":"2948_CR22","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1016\/j.jacc.2014.09.080","volume":"65","author":"C Tribouilloy","year":"2015","unstructured":"Tribouilloy C, Rusinaru D, Marechaux S, Castel AL, Debry N, Maizel J, Mentaverri R, Kamel S, Slama M, Levy F (2015) Low-gradient, low-flow severe aortic stenosis with preserved left ventricular ejection fraction: characteristics, outcome, and implications for surgery. J Am Coll Cardiol 65:55\u201366","journal-title":"J Am Coll Cardiol"},{"key":"2948_CR23","doi-asserted-by":"publisher","first-page":"1375","DOI":"10.1136\/heartjnl-2015-307528","volume":"101","author":"DH Kang","year":"2015","unstructured":"Kang DH, Jang JY, Park SJ, Kim DH, Yun SC, Song JM, Park SW, Chung CH, Song JK, Lee JW (2015) Watchful observation versus early aortic valve replacement for symptomatic patients with normal flow, low-gradient severe aortic stenosis. Heart 101:1375\u20131381","journal-title":"Heart"},{"key":"2948_CR24","doi-asserted-by":"publisher","first-page":"2594","DOI":"10.1016\/j.jacc.2015.09.076","volume":"66","author":"V Dayan","year":"2015","unstructured":"Dayan V, Vignolo G, Magne J, Clavel MA, Mohty D, Pibarot P (2015) Outcome and impact of aortic valve replacement in patients with preserved LVEF and low-gradient aortic stenosis. J Am Coll Cardiol 66:2594\u20132603","journal-title":"J Am Coll Cardiol"},{"key":"2948_CR25","doi-asserted-by":"publisher","first-page":"2329","DOI":"10.1016\/j.jacc.2013.08.1621","volume":"62","author":"MA Clavel","year":"2013","unstructured":"Clavel MA, Messika-Zeitoun D, Pibarot P, Aggarwal SR, Malouf J, Araoz PA, Michelena HI, Cueff C, Larose E, Capoulade R, Vahanian A, Enriquez-Sarano M (2013) The complex nature of discordant severe calcified aortic valve disease grading: new insights from combined Doppler echocardiographic and computed tomographic study. J Am Coll Cardiol 62:2329\u20132338","journal-title":"J Am Coll Cardiol"},{"key":"2948_CR26","doi-asserted-by":"publisher","first-page":"1325","DOI":"10.1007\/s00392-022-02011-4","volume":"111","author":"J Steffen","year":"2022","unstructured":"Steffen J, Reissig N, Andreae D, Beckmann M, Haum M, Fischer J, Theiss H, Braun D, Orban M, Rizas K, Sadoni S, Nabauer M, Peterss S, Hausleiter J, Massberg S, Deseive S (2022) TAVI in patients with low-flow low-gradient aortic stenosis-short-term and long-term outcomes. Clin Res Cardiol 111:1325\u20131335","journal-title":"Clin Res Cardiol"},{"key":"2948_CR27","doi-asserted-by":"publisher","first-page":"2316","DOI":"10.1161\/CIRCULATIONAHA.112.001290","volume":"127","author":"HC Herrmann","year":"2013","unstructured":"Herrmann HC, Pibarot P, Hueter I, Gertz ZM, Stewart WJ, Kapadia S, Tuzcu EM, Babaliaros V, Thourani V, Szeto WY, Bavaria JE, Kodali S, Hahn RT, Williams M, Miller DC, Douglas PS, Leon MB (2013) Predictors of mortality and outcomes of therapy in low-flow severe aortic stenosis: a Placement of Aortic Transcatheter Valves (PARTNER) trial analysis. Circulation 127:2316\u20132326","journal-title":"Circulation"},{"key":"2948_CR28","doi-asserted-by":"publisher","first-page":"850","DOI":"10.4244\/EIJV10I7A145","volume":"10","author":"A Lauten","year":"2014","unstructured":"Lauten A, Figulla HR, Mollmann H, Holzhey D, Kotting J, Beckmann A, Veit C, Cremer J, Kuck KH, Lange R, Zahn R, Sack S, Schuler G, Walther T, Beyersdorf F, Bohm M, Heusch G, Meinertz T, Neumann T, Welz A, Mohr FW, Hamm CW, Board GE (2014) TAVI for low-flow, low-gradient severe aortic stenosis with preserved or reduced ejection fraction: a subgroup analysis from the German Aortic Valve Registry (GARY). EuroIntervention 10:850\u2013859","journal-title":"EuroIntervention"},{"key":"2948_CR29","doi-asserted-by":"publisher","first-page":"1033","DOI":"10.1536\/ihj.24-284","volume":"65","author":"Y Yamashita","year":"2024","unstructured":"Yamashita Y, Baudo M, Sicouri S, Zafar M, Rodriguez R, Gnall EM, Coady PM, Goldman SM, Gray WA, Ramlawi B (2024) Impact of flow-gradient patterns on outcomes of transcatheter aortic valve replacement for severe aortic stenosis with preserved left ventricular ejection fraction. Int Heart J 65:1033\u20131039","journal-title":"Int Heart J"},{"key":"2948_CR30","doi-asserted-by":"publisher","first-page":"887","DOI":"10.1161\/CIRCULATIONAHA.110.983510","volume":"123","author":"N Jander","year":"2011","unstructured":"Jander N, Minners J, Holme I, Gerdts E, Boman K, Brudi P, Chambers JB, Egstrup K, Kesaniemi YA, Malbecq W, Nienaber CA, Ray S, Rossebo A, Pedersen TR, Skjaerpe T, Willenheimer R, Wachtell K, Neumann FJ, Gohlke-Barwolf C (2011) Outcome of patients with low-gradient \u201csevere\u201d aortic stenosis and preserved ejection fraction. Circulation 123:887\u2013895","journal-title":"Circulation"},{"key":"2948_CR31","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcha.2020.100539","volume":"28","author":"D Mele","year":"2020","unstructured":"Mele D, Pestelli G, Dal Molin D, Fiorencis A, Flamigni F, Luisi GA, Smarrazzo V, Trevisan F, Ferrari R (2020) Paradoxical low-flow phenotype in hospitalized heart failure with preserved ejection fraction. IJC Heart Vasc 28:100539","journal-title":"IJC Heart Vasc"},{"key":"2948_CR32","doi-asserted-by":"publisher","first-page":"302","DOI":"10.1093\/ehjci\/jead276","volume":"25","author":"S Hoedemakers","year":"2024","unstructured":"Hoedemakers S, Verwerft J, Reddy YNV, Delvaux R, Stroobants S, Jogani S, Claessen G, Droogmans S, Cosyns B, Borlaug BA, Herbots L, Verbrugge FH (2024) Cardiac dysfunction rather than aortic valve stenosis severity drives exercise intolerance and adverse haemodynamics. Eur Heart J Cardiovasc Imaging 25:302\u2013312","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"2948_CR33","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1016\/j.jacc.2014.10.030","volume":"65","author":"P Pibarot","year":"2015","unstructured":"Pibarot P, Clavel MA (2015) Management of paradoxical low-flow, low-gradient aortic stenosis: need for an integrated approach, including assessment of symptoms, hypertension, and stenosis severity. J Am Coll Cardiol 65:67\u201371","journal-title":"J Am Coll Cardiol"},{"key":"2948_CR34","first-page":"e72","volume":"143","author":"CM Otto","year":"2021","unstructured":"Otto CM, Nishimura RA, Bonow RO, Carabello BA, Erwin JP 3rd, Gentile F, Jneid H, Krieger EV, Mack M, McLeod C, O\u2019Gara PT, Rigolin VH, Sundt TM 3rd, Thompson A, Toly C (2021) 2020 ACC\/AHA guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology\/American Heart Association Joint Committee on Clinical Practice Guidelines. Circulation 143:e72\u2013e227","journal-title":"Circulation"},{"key":"2948_CR35","doi-asserted-by":"publisher","first-page":"1196","DOI":"10.1161\/01.CIR.91.4.1196","volume":"91","author":"W Voelker","year":"1995","unstructured":"Voelker W, Reul H, Nienhaus G, Stelzer T, Schmitz B, Steegers A, Karsch KR (1995) Comparison of valvular resistance, stroke work loss, and Gorlin valve area for quantification of aortic stenosis. An in vitro study in a pulsatile aortic flow model. Circulation 91:1196\u2013204","journal-title":"Circulation"}],"container-title":["Clinical Research in Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00392-026-02948-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00392-026-02948-w","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00392-026-02948-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T15:36:06Z","timestamp":1780414566000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00392-026-02948-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,2]]},"references-count":35,"alternative-id":["2948"],"URL":"https:\/\/doi.org\/10.1007\/s00392-026-02948-w","relation":{},"ISSN":["1861-0684","1861-0692"],"issn-type":[{"value":"1861-0684","type":"print"},{"value":"1861-0692","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,2]]},"assertion":[{"value":"17 July 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 May 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 June 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Data of this work were derived from a prospective registry (Post-TAVI registry: NCT03192774) approved by the local ethics committee (\u00c4rztekammer Schleswig\u2013Holstein) and conforming to the Declaration of Helsinki. All patients included in this study have provided a written consent for participation in the local prospective TAVI registry and for a systematic follow-up.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Prof. Gert Richardt has received institutional research grants from Biotronik and Medtronic. Dr. Mankerious is a proctor for Boston Scientific and received speaker\u2019s honoraria from Biotronik and Boston Scientific. Dr. Abdelhakim Allali is consultant and proctor for Boston Scientific. Other authors have nothing to disclose.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Medical writing and editing was performed by the corresponding author and reviewed from the co-authors, without external company assistance.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Medical writing\/editorial assistance"}}]}}