{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T09:08:56Z","timestamp":1783069736659,"version":"3.54.6"},"reference-count":19,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2020,10,14]],"date-time":"2020-10-14T00:00:00Z","timestamp":1602633600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,10,14]],"date-time":"2020-10-14T00:00:00Z","timestamp":1602633600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Z Rheumatol"],"published-print":{"date-parts":[[2020,11]]},"DOI":"10.1007\/s00393-020-00899-9","type":"journal-article","created":{"date-parts":[[2020,10,14]],"date-time":"2020-10-14T14:03:14Z","timestamp":1602684194000},"page":"873-882","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Beh\u00e7et-Syndrom","Beh\u00e7et\u2019s syndrome"],"prefix":"10.1007","volume":"79","author":[{"given":"I.","family":"K\u00f6tter","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,10,14]]},"reference":[{"key":"899_CR1","first-page":"16","volume":"71","author":"N Rasmussen","year":"2012","unstructured":"Rasmussen\u00a0N (2012) The 2012 revised international Chapel Hill consensus nomenclature of the vasculitides. Ann Rheum Dis 71:16","journal-title":"Ann Rheum Dis"},{"key":"899_CR2","first-page":"1152","volume":"105","author":"H Behcet","year":"1937","unstructured":"Behcet\u00a0H (1937) \u00dcber rezidivierende, aphth\u00f6se, durch ein Virus verursachte Geschw\u00fcre im Mund, am Auge und an den Genitalien. Dermatol Wochenschr 105:1152\u20131157","journal-title":"Dermatol Wochenschr"},{"key":"899_CR3","first-page":"586","volume-title":"A case of relapsing iritis with hypopion","author":"B Adamantiades","year":"1930","unstructured":"Adamantiades\u00a0B (1930) A case of relapsing iritis with hypopion. Proceedings of hte Medical Society of Athens, Athen, S\u00a0586\u2013539"},{"key":"899_CR4","first-page":"808","volume":"77","author":"G Hatemi","year":"2018","unstructured":"Hatemi\u00a0G, Christensen\u00a0R, Bang\u00a0D, Bodaghi\u00a0B, Celik\u00a0AF et\u00a0al (2018) 2018 update of the EULAR recommendations for the management of Behcet\u2019s syndrome. Ann Rheum Dis 77:808\u2013818","journal-title":"Ann Rheum Dis"},{"key":"899_CR5","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1016\/j.revmed.2013.12.005","volume":"35","author":"A Mahr","year":"2014","unstructured":"Mahr\u00a0A, Maldini\u00a0C (2014) Epidemiology of Behcet\u2019s disease. Rev Med Interne 35:81\u201389","journal-title":"Rev Med Interne"},{"key":"899_CR6","first-page":"133","volume":"31","author":"I Kotter","year":"2004","unstructured":"Kotter\u00a0I, Vonthein\u00a0R, Muller\u00a0CA, Gunaydin\u00a0I, Zierhut\u00a0M, Stubiger\u00a0N (2004) Behcet\u2019s disease in patients of German and Turkish origin living in Germany: a\u00a0comparative analysis. J\u00a0Rheumatol 31:133\u2013139","journal-title":"J Rheumatol"},{"key":"899_CR7","first-page":"1078","volume":"335","author":"International Study Group for Behcet\u2019s Disease","year":"1990","unstructured":"International Study Group for Behcet\u2019s Disease (1990) Criteria for diagnosis of Behcet\u2019s disease. Lancet 335:1078\u20131080","journal-title":"Lancet"},{"key":"899_CR8","doi-asserted-by":"publisher","first-page":"338","DOI":"10.1111\/jdv.12107","volume":"28","author":"International Team for the Revision of the International Criteria for Behcet\u2019s Disease","year":"2014","unstructured":"International Team for the Revision of the International Criteria for Behcet\u2019s Disease (2014) The international criteria for Behcet\u2019s disease (ICBD): a\u00a0collaborative study of 27\u00a0countries on the sensitivity and specificity of the new criteria. J\u00a0Eur Acad Dermatol Venereol 28:338\u2013347","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"899_CR9","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1136\/practneurol-2011-000072","volume":"11","author":"MR Baker","year":"2011","unstructured":"Baker\u00a0MR, Smith\u00a0EV, Seidi\u00a0OA (2011) Pathergy test. Pract Neurol 11:301\u2013302","journal-title":"Pract Neurol"},{"key":"899_CR10","doi-asserted-by":"publisher","first-page":"677","DOI":"10.1007\/s11739-019-02046-y","volume":"14","author":"E Seyahi","year":"2019","unstructured":"Seyahi\u00a0E (2019) Phenotypes in Behcet\u2019s syndrome. Intern Emerg Med 14:677\u2013689","journal-title":"Intern Emerg Med"},{"key":"899_CR11","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1038\/nrrheum.2012.156","volume":"9","author":"NL Ambrose","year":"2013","unstructured":"Ambrose\u00a0NL, Haskard\u00a0DO (2013) Differential diagnosis and management of Behcet syndrome. Nat Rev Rheumatol 9:79\u201389","journal-title":"Nat Rev Rheumatol"},{"key":"899_CR12","doi-asserted-by":"publisher","first-page":"793","DOI":"10.1016\/j.berh.2008.08.005","volume":"22","author":"S Yurdakul","year":"2008","unstructured":"Yurdakul\u00a0S, Yazici\u00a0H (2008) Behcet\u2019s syndrome. Best Pract Res Clin Rheumatol 22:793\u2013809","journal-title":"Best Pract Res Clin Rheumatol"},{"key":"899_CR13","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1097\/00005792-200301000-00006","volume":"82","author":"E Kural-Seyahi","year":"2003","unstructured":"Kural-Seyahi\u00a0E, Fresko\u00a0I, Seyahi\u00a0N, Ozyazgan\u00a0Y, Mat\u00a0C et al (2003) The long-term mortality and morbidity of Behcet syndrome: a\u00a02-decade outcome survey of 387\u00a0patients followed at a\u00a0dedicated center. Medicine (Baltimore) 82:60\u201376","journal-title":"Medicine (Baltimore)"},{"key":"899_CR14","doi-asserted-by":"publisher","first-page":"2753","DOI":"10.1002\/art.34450","volume":"64","author":"AC Desbois","year":"2012","unstructured":"Desbois\u00a0AC, Wechsler\u00a0B, Resche-Rigon\u00a0M, Piette\u00a0JC, Huong Dle\u00a0T et al (2012) Immunosuppressants reduce venous thrombosis relapse in Behcet\u2019s disease. Arthritis Rheum 64:2753\u20132760","journal-title":"Arthritis Rheum"},{"key":"899_CR15","doi-asserted-by":"publisher","first-page":"932","DOI":"10.1056\/NEJMoa1509852","volume":"375","author":"GJ Jaffe","year":"2016","unstructured":"Jaffe\u00a0GJ, Dick\u00a0AD, Brezin\u00a0AP, Nguyen\u00a0QD, Thorne\u00a0JE et\u00a0al (2016) Adalimumab in patients with active noninfectious uveitis. N\u00a0Engl J Med 375:932\u2013943","journal-title":"N Engl J Med"},{"key":"899_CR16","doi-asserted-by":"publisher","first-page":"1918","DOI":"10.1056\/NEJMoa1816594","volume":"381","author":"G Hatemi","year":"2019","unstructured":"Hatemi\u00a0G, Mahr\u00a0A, Ishigatsubo\u00a0Y, Song\u00a0YW, Takeno\u00a0M et\u00a0al (2019) Trial of apremilast for oral ulcers in Behcet\u2019s syndrome. N\u00a0Engl J Med 381:1918\u20131928","journal-title":"N Engl J Med"},{"key":"899_CR17","doi-asserted-by":"publisher","first-page":"1510","DOI":"10.1056\/NEJMoa1408684","volume":"372","author":"G Hatemi","year":"2015","unstructured":"Hatemi\u00a0G, Melikoglu\u00a0M, Tunc\u00a0R, Korkmaz\u00a0C, Turgut Ozturk\u00a0B et al (2015) Apremilast for Behcet\u2019s syndrome\u2014a phase 2, placebo-controlled study. N\u00a0Engl J Med 372:1510\u20131518","journal-title":"N Engl J Med"},{"key":"899_CR18","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1016\/j.ajo.2004.03.022","volume":"138","author":"I Tugal-Tutkun","year":"2004","unstructured":"Tugal-Tutkun\u00a0I, Onal\u00a0S, Altan-Yaycioglu\u00a0R, Huseyin Altunbas\u00a0H, Urgancioglu\u00a0M (2004) Uveitis in Behcet disease: an analysis of 880\u00a0patients. Am J Ophthalmol 138:373\u2013380","journal-title":"Am J Ophthalmol"},{"issue":"2","key":"899_CR19","first-page":"1","volume":"23","author":"YR Chung","year":"2014","unstructured":"Chung\u00a0YR, Lee\u00a0ES, Kim\u00a0MH, Lew\u00a0HM, Song\u00a0JH (2014) Changes in ocular manifestations of Behcet disease in Korean patients over time: a single-center experience in the 1990s and 2000s. Ocul Immunol Inflamm 23(2):1\u20135","journal-title":"Ocul Immunol Inflamm"}],"container-title":["Zeitschrift f\u00fcr Rheumatologie"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00393-020-00899-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00393-020-00899-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00393-020-00899-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,14]],"date-time":"2021-10-14T01:18:31Z","timestamp":1634174311000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00393-020-00899-9"}},"subtitle":["Aktuelle Diagnostik und Therapie","Current diagnostics and treatment"],"short-title":[],"issued":{"date-parts":[[2020,10,14]]},"references-count":19,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2020,11]]}},"alternative-id":["899"],"URL":"https:\/\/doi.org\/10.1007\/s00393-020-00899-9","relation":{},"ISSN":["0340-1855","1435-1250"],"issn-type":[{"value":"0340-1855","type":"print"},{"value":"1435-1250","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,10,14]]},"assertion":[{"value":"14 October 2020","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Einhaltung ethischer Richtlinien"}},{"value":"Gem\u00e4\u00df den Richtlinien des Springer Medizin Verlags werden Autoren und Wissenschaftliche Leitung im Rahmen der Manuskripterstellung und Manuskriptfreigabe aufgefordert, eine vollst\u00e4ndige Erkl\u00e4rung zu ihren finanziellen und nichtfinanziellen Interessen abzugeben.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}},{"value":"<b>I.\u00a0K\u00f6tter<\/b>: A. Finanzielle Interessen: Referentenhonorar oder Kostenerstattung als passiver Teilnehmer: AbbVie, Boehringer Ingelheim, Chugai, Celgene, Janssen, GSK, Lilly, Medac, MSD, Novartis, Pfizer, Roche, Sobi. \u2013 B. Nichtfinanzielle Interessen: Chef\u00e4rztin, Asklepios Klinik Altona (03\/2014 bis 09\/2019), Direktorin, Klinikum Bad Bramstedt und Leiterin Sektion Rheumatologie und Entz\u00fcndliche Systemerkrankungen, UKE Hamburg (seit 01.10.2019) | Mitgliedschaften: BDRH, DGRH (Beirat), International Society for Behcet\u2019s Disease (Beirat), ACR, Deutsche Gesellschaft f\u00fcr Immunologie, Rheumatologische Fortbildungsakademie (wiss. Kuratorium), Kooperatives Rheumazentrum Hamburg (Vorsitzende).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Autoren"}},{"value":"Die vollst\u00e4ndige Erkl\u00e4rung zum Interessenkonflikt der Wissenschaftlichen Leitung finden Sie am Kurs der zertifizierten Fortbildung auf .","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Wissenschaftliche Leitung"}},{"value":"erkl\u00e4rt, dass f\u00fcr die Publikation dieser CME-Fortbildung keine Sponsorengelder an den Verlag flie\u00dfen.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Der Verlag"}},{"value":"F\u00fcr diesen Beitrag wurden von den Autoren keine Studien an Menschen oder Tieren durchgef\u00fchrt. F\u00fcr die aufgef\u00fchrten Studien gelten die jeweils dort angegebenen ethischen Richtlinien. F\u00fcr Bildmaterial oder anderweitige Angaben innerhalb des Manuskripts, \u00fcber die Patienten zu identifizieren sind, liegt von ihnen und\/oder ihren gesetzlichen Vertretern eine schriftliche Einwilligung vor.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Der Verlag"}}]}}