{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,29]],"date-time":"2022-03-29T22:26:43Z","timestamp":1648592803182},"reference-count":62,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2021,5,27]],"date-time":"2021-05-27T00:00:00Z","timestamp":1622073600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,5,27]],"date-time":"2021-05-27T00:00:00Z","timestamp":1622073600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Z Rheumatol"],"published-print":{"date-parts":[[2021,8]]},"DOI":"10.1007\/s00393-021-01014-2","type":"journal-article","created":{"date-parts":[[2021,5,27]],"date-time":"2021-05-27T17:10:49Z","timestamp":1622135449000},"page":"539-551","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Update: enteropathische Spondyloarthritis"],"prefix":"10.1007","volume":"80","author":[{"given":"Elisabeth","family":"M\u00e4rker-Hermann","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,5,27]]},"reference":[{"key":"1014_CR1","doi-asserted-by":"publisher","first-page":"451","DOI":"10.1016\/j.berh.2006.03.010","volume":"20","author":"M Rudwaleit","year":"2006","unstructured":"Rudwaleit\u00a0M, Baeten\u00a0D (2006) Ankylosing spondylitis and bowel disease. Best Pract Res Clin Rheumatol 20:451","journal-title":"Best Pract Res Clin Rheumatol"},{"key":"1014_CR2","doi-asserted-by":"publisher","first-page":"2148","DOI":"10.3899\/jrheum.120321","volume":"39","author":"R Shivashankar","year":"2012","unstructured":"Shivashankar\u00a0R, Loftus\u00a0EV Jr, Tremaine\u00a0WJ, Bongartz\u00a0T, Harmsen\u00a0WS, Zinsmeister\u00a0AR (2012) Matteson EL Incidence of spondyloarthropathy in patients with Crohn\u2019s disease: a\u00a0population-based study. J\u00a0Rheumatol 39:2148\u20132152","journal-title":"J Rheumatol"},{"key":"1014_CR3","doi-asserted-by":"publisher","first-page":"1153","DOI":"10.3899\/jrheum.121029","volume":"40","author":"R Shivashankar","year":"2013","unstructured":"Shivashankar\u00a0R, Loftus\u00a0EV Jr, Tremaine\u00a0WJ, Harmsen\u00a0WS, Zinsmeister\u00a0AR, Matteson\u00a0EL (2013) Incidence of Spondyloarthropathy in patients with ulcerative colitis: a\u00a0population-based study. J\u00a0Rheumatol 40:1153\u20131157","journal-title":"J Rheumatol"},{"key":"1014_CR4","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1038\/ajg.2010.343","volume":"106","author":"SR Vavricka","year":"2011","unstructured":"Vavricka\u00a0SR, Brun\u00a0L, Ballabeni\u00a0P et\u00a0al (2011) Frequency and risk factors for extraintestinal manifestations in the Swiss inflammatory bowel disease cohort. Am J Gastroenterol 106:110\u2013119","journal-title":"Am J Gastroenterol"},{"key":"1014_CR5","first-page":"631","volume":"11","author":"MC Karreman","year":"2017","unstructured":"Karreman\u00a0MC, Luime\u00a0JJ, Hazes\u00a0JM, Weel\u00a0AE (2017) The prevalence and incidence of axial and peripheral spondyloarthritis in inflammatory bowel disease: a systematic review and meta-analysis. J\u00a0Crohns Colitis 11:631\u2013642","journal-title":"J Crohns Colitis"},{"key":"1014_CR6","doi-asserted-by":"publisher","first-page":"274","DOI":"10.1016\/S0016-5085(00)70209-5","volume":"118","author":"TR Orchard","year":"2000","unstructured":"Orchard\u00a0TR, Thiyagaraja\u00a0S, Welsh\u00a0KI, Wordsworth\u00a0BP, Hill Gaston\u00a0JS, Jewell\u00a0DP (2000) Clinical phenotype is related to HLA genotype in the peripheral arthropathies of inflammatory bowel disease. Gastroenterology 118:274\u2013278","journal-title":"Gastroenterology"},{"key":"1014_CR7","doi-asserted-by":"publisher","first-page":"1131","DOI":"10.1136\/ard.2004.021774","volume":"63","author":"H Peeters","year":"2004","unstructured":"Peeters\u00a0H, Vander Cruyssen\u00a0B, Laukens\u00a0D et\u00a0al (2004) Radiological sacroiliitis, a\u00a0hallmark of spondylitis, is linked with CARD15 gene polymorphisms in patients with Crohn\u2019s disease. Ann Rheum Dis 63:1131\u20131134","journal-title":"Ann Rheum Dis"},{"key":"1014_CR8","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1007\/s11377-012-0726-2","volume":"8","author":"J Zeitz","year":"2013","unstructured":"Zeitz\u00a0J, Vavricka\u00a0SR (2013) Therapie der extraintestinalen CED-Manifestationen : Eine schwierige Herausforderung. Gastroenterologe 8:217\u2013225","journal-title":"Gastroenterologe"},{"key":"1014_CR9","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1097\/00042737-199707000-00013","volume":"9","author":"S Travis","year":"1997","unstructured":"Travis\u00a0S (1997) Sweet\u2019s syndrome: an unusual cutaneous feature of Crohn\u2019s disease or ulcerative colitis. The south west gastroenterology group. Eur J Gastroenterol Hepatol 9:15\u2013720","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"1014_CR10","doi-asserted-by":"publisher","first-page":"1786","DOI":"10.1055\/a-1036-9359","volume":"145","author":"E M\u00e4rker-Hermann","year":"2020","unstructured":"M\u00e4rker-Hermann\u00a0E (2020) Reaktive Arthritis \u2013 eine vergessene Erkrankung? Dtsch Med Wochenschr 145:1786\u20131790","journal-title":"Dtsch Med Wochenschr"},{"key":"1014_CR11","doi-asserted-by":"publisher","first-page":"299","DOI":"10.3329\/jhpn.v31i3.16515","volume":"31","author":"AN Ajene","year":"2013","unstructured":"Ajene\u00a0AN, Fischer Walker\u00a0CL, Black\u00a0RE (2013) Enteric pathogens and reactive arthritis: a\u00a0systematic review of campylobacter, salmonella and shigella-associated reactive arthritis. J\u00a0Health Popul Nutr 31:299","journal-title":"J Health Popul Nutr"},{"key":"1014_CR12","doi-asserted-by":"publisher","first-page":"1793","DOI":"10.1136\/annrheumdis-2013-203431","volume":"73","author":"M Vasala","year":"2014","unstructured":"Vasala\u00a0M, Hallanvuo\u00a0S, Ruuska\u00a0P et\u00a0al (2014) High frequency of reactive arthritis in adults after Yersinia pseudotuberculosis O:1 outbreak caused by contaminated grated carrots. Ann Rheum Dis 73:1793\u20131796","journal-title":"Ann Rheum Dis"},{"key":"1014_CR13","doi-asserted-by":"publisher","first-page":"605","DOI":"10.1136\/annrheumdis-2019-216736","volume":"79","author":"R Tuompo","year":"2020","unstructured":"Tuompo\u00a0R, L\u00e4\u00e4veri\u00a0T, Hannu\u00a0T et\u00a0al (2020) Reactive arthritis and other musculoskeletal symptoms associated with acquisition of diarrhoeagenic\u00a0escherichia coli\u00a0(DEC). Ann Rheum Dis 79:605\u2013611","journal-title":"Ann Rheum Dis"},{"key":"1014_CR14","first-page":"2273","volume":"22","author":"H Mielants","year":"1995","unstructured":"Mielants\u00a0H, Veys\u00a0EM, Cuvelier\u00a0C et\u00a0al (1995) The evolution of spondyloarthropathies in relation to gut histology. II. Histological aspects. J\u00a0Rheumatol 22:2273\u20132278","journal-title":"J Rheumatol"},{"key":"1014_CR15","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1016\/S0950-3579(96)80010-0","volume":"10","author":"H Mielants","year":"1996","unstructured":"Mielants\u00a0H, Veys\u00a0EM, Cuvelier\u00a0C, De Vos\u00a0M (1996) Course of gut inflammation in spondylarthropathies and therapeutic consequences. Baillieres Clin Rheumatol 10:147\u2013164","journal-title":"Baillieres Clin Rheumatol"},{"key":"1014_CR16","doi-asserted-by":"publisher","first-page":"414","DOI":"10.1136\/annrheumdis-2012-202135","volume":"72","author":"L Van Praet","year":"2013","unstructured":"Van Praet\u00a0L, Van den Bosch\u00a0FE, Jacques\u00a0P et\u00a0al (2013) Microscopic gut inflammation in axial spondyloarthritis: a\u00a0multiparametric predictive model. Ann Rheum Dis 72:414\u2013417","journal-title":"Ann Rheum Dis"},{"issue":"1","key":"1014_CR17","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1186\/s13075-017-1223-2","volume":"19","author":"E Klingberg","year":"2017","unstructured":"Klingberg\u00a0E, Strid\u00a0H, St\u00e5hl\u00a0A et\u00a0al (2017) A longitudinal study of fecal calprotectin and the development of inflammatory bowel disease in ankylosing spondylitis. Arthritis Res Ther 19(1):21","journal-title":"Arthritis Res Ther"},{"key":"1014_CR18","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1136\/ard.2010.133645","volume":"70","author":"M Rudwaleit","year":"2011","unstructured":"Rudwaleit\u00a0M, van der Heijde\u00a0D, Landewe\u00a0R et\u00a0al (2011) The assessment of spondyloarthritis international society classification criteria for peripheral spondyloarthritis and for spondyloarthritis in general. Ann Rheum Dis 70:25\u201331","journal-title":"Ann Rheum Dis"},{"key":"1014_CR19","doi-asserted-by":"publisher","first-page":"777","DOI":"10.1136\/ard.2009.108233","volume":"68","author":"M Rudwaleit","year":"2009","unstructured":"Rudwaleit\u00a0M, van der Heijde\u00a0D, Landewe\u00a0R et\u00a0al (2009) The development of assessment of spondyloarthritis international society classification criteria for axial spondyloarthritis (part II): validation and final selection. Ann Rheum Dis 68:777\u2013783","journal-title":"Ann Rheum Dis"},{"key":"1014_CR20","doi-asserted-by":"publisher","first-page":"807","DOI":"10.1002\/acr.23323","volume":"70","author":"J Chan","year":"2018","unstructured":"Chan\u00a0J, Sari\u00a0I, Salonen\u00a0D, Silverberg\u00a0MS et\u00a0al (2018) Prevalence of sacroiliitis in inflammatory bowel disease using a\u00a0standardized CT scoring system. Arthritis Care Res (Hoboken) 70:807\u2013810","journal-title":"Arthritis Care Res (Hoboken)"},{"key":"1014_CR21","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1007\/s00393-019-0670-3","volume":"78","author":"U Kiltz","year":"2019","unstructured":"Kiltz\u00a0U, Braun\u00a0J, DGRh et al (2019) Langfassung zur S3-Leitlinie Axiale Spondyloarthritis inklusive Morbus Bechterew und Fr\u00fchformen, Update 2019. Z\u00a0Rheumatol 78:3\u201364","journal-title":"Z Rheumatol"},{"key":"1014_CR22","doi-asserted-by":"publisher","first-page":"957","DOI":"10.1111\/apt.12680","volume":"39","author":"S Leclerc-Jacob","year":"2014","unstructured":"Leclerc-Jacob\u00a0S, Lux\u00a0G, Rat\u00a0AC et al (2014) The prevalence of inflammatory sacroiliitis assessed on magnetic resonance imaging of inflammatory bowel disease: a\u00a0retrospective study performed on 186\u00a0patients. Aliment Pharmacol Ther 39:957\u2013962","journal-title":"Aliment Pharmacol Ther"},{"key":"1014_CR23","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1136\/ard.2007.084251","volume":"68","author":"E de Miguel","year":"2009","unstructured":"de Miguel\u00a0E, Cobo\u00a0T, Mu\u00f1oz-Fern\u00e1ndez\u00a0S et al (2009) Validity of enthesis ultrasound assessment in spondyloarthropathy. Ann Rheum Dis 68:169\u2013174","journal-title":"Ann Rheum Dis"},{"key":"1014_CR24","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1097\/00054725-200301000-00001","volume":"9","author":"MS Silverberg","year":"2003","unstructured":"Silverberg\u00a0MS, Mirea\u00a0L, Bull\u00a0SB et al (2003) A population- and family-based study of Canadian families reveals association of HLA DRB1*0103 with colonic involvement in inflammatory bowel disease. Inflamm Bowel Dis 9:1\u20139","journal-title":"Inflamm Bowel Dis"},{"key":"1014_CR25","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1093\/ecco-jcc\/jjx126","volume":"12","author":"AM Ossum","year":"2018","unstructured":"Ossum\u00a0AM, Palm \u00d8, Lunder\u00a0AK et al (2018) Ankylosing spondylitis and axial spondyloarthritis in patients with long-term inflammatory bowel disease: results from 20\u00a0years of follow-up in the IBSEN study. J\u00a0Crohns Colitis 12:96\u2013104","journal-title":"J Crohns Colitis"},{"issue":"1","key":"1014_CR26","doi-asserted-by":"publisher","first-page":"S19","DOI":"10.1016\/S1521-6918(11)70006-3","volume":"25","author":"M De Vos","year":"2011","unstructured":"De Vos\u00a0M, Hindryckx\u00a0P, Laukens\u00a0D (2011) Novel development in extraintestinal manifestations and spondylarthropathy. Best Pract Res Clin Gastroenterol 25(1):S19\u2013S26","journal-title":"Best Pract Res Clin Gastroenterol"},{"key":"1014_CR27","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1038\/sj.gene.6363914","volume":"4","author":"M van der Paardt","year":"2003","unstructured":"van der Paardt\u00a0M, Crusius\u00a0JBA, de Koning\u00a0MHMT et\u00a0al (2003) CARD15 gene mutations are not associated with ankylosing spondylitis. Genes Immun 4:77\u201378","journal-title":"Genes Immun"},{"key":"1014_CR28","first-page":"187","volume":"41","author":"M D\u2019Amato","year":"2014","unstructured":"D\u2019Amato\u00a0M, Sorrentino\u00a0R, Pettersson\u00a0S (2014) The Crohn\u2019s associated NOD2 3020InsC frameshift mutation does not confer susceptibility to ankylosing spondylitis. J\u00a0Rheumatol 41:187","journal-title":"J Rheumatol"},{"key":"1014_CR29","doi-asserted-by":"publisher","first-page":"930","DOI":"10.1136\/ard.2004.028837","volume":"64","author":"D Laukens","year":"2005","unstructured":"Laukens\u00a0D, Peeters\u00a0H, Marichal\u00a0D et\u00a0al (2005) CARD15 gene polymorphisms in patients with spondyloarthropathies identify a\u00a0specific phenotype previously related to Crohn\u2019s disease. Ann Rheum Dis 64:930\u2013935","journal-title":"Ann Rheum Dis"},{"key":"1014_CR30","doi-asserted-by":"publisher","first-page":"e1001195","DOI":"10.1371\/journal.pgen.1001195","volume":"6","author":"P Danoy","year":"2010","unstructured":"Danoy\u00a0P, Pryce\u00a0K, Hadler\u00a0J et\u00a0al (2010) Association of variants at 1q32 and STAT3 with ankylosing spondylitis suggests genetic overlap with Crohn\u2019s disease. PLoS Genet 6:e1001195","journal-title":"PLoS Genet"},{"key":"1014_CR31","doi-asserted-by":"publisher","first-page":"e13795","DOI":"10.1371\/journal.pone.0013795","volume":"5","author":"D Laukens","year":"2010","unstructured":"Laukens\u00a0D, Georges\u00a0M, Libioulle\u00a0C et\u00a0al (2010) Evidence for significant overlap between common risk variants for Crohn\u2019s disease and ankylosing spondylitis. PLoS One 5:e13795","journal-title":"PLoS One"},{"key":"1014_CR32","doi-asserted-by":"publisher","first-page":"490","DOI":"10.1038\/gene.2010.17","volume":"11","author":"JJ Pointon","year":"2010","unstructured":"Pointon\u00a0JJ, Harvey\u00a0D, Karaderi\u00a0T et\u00a0al (2010) Elucidating the chromosome 9 association with AS; CARD9 is a\u00a0candidate gene. Genes Immun 11:490\u2013496","journal-title":"Genes Immun"},{"key":"1014_CR33","doi-asserted-by":"publisher","first-page":"1461","DOI":"10.1126\/science.1135245","volume":"314","author":"RH Duerr","year":"2006","unstructured":"Duerr\u00a0RH, Taylor\u00a0KD, Brant\u00a0SR et al (2006) A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. Science 314:1461\u20131463","journal-title":"Science"},{"key":"1014_CR34","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1038\/ng.513","volume":"42","author":"The Australo-Anglo-American Spondyloarthritis Consortium (TASC)","year":"2010","unstructured":"The Australo-Anglo-American Spondyloarthritis Consortium (TASC) (2010) Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci. Nat Genet 42:123\u2013127","journal-title":"Nat Genet"},{"key":"1014_CR35","doi-asserted-by":"publisher","first-page":"443","DOI":"10.1136\/gut.40.4.443","volume":"40","author":"SJ Van Deventer","year":"1997","unstructured":"Van Deventer\u00a0SJ (1997) Tumour necrosis factor and crohn\u2019s disease. Gut 40:443\u2013448","journal-title":"Gut"},{"key":"1014_CR36","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1093\/intimm\/dxu051","volume":"26","author":"M Leppkes","year":"2014","unstructured":"Leppkes\u00a0M, Roulis\u00a0M, Neurath\u00a0MF et al (2014) Pleiotropic functions of TNF\u2011\u03b1 in the regulation of the intestinal epithelial response to inflammation. Int Immunol 26:509\u2013515","journal-title":"Int Immunol"},{"key":"1014_CR37","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1007\/s10067-010-1647-4","volume":"30","author":"Y Mei","year":"2011","unstructured":"Mei\u00a0Y, Pan\u00a0F, Gao\u00a0J et al (2011) Increased serum IL-17 and IL-23 in the patient with ankylosing spondylitis. Clin Rheumatol 30:269\u2013273","journal-title":"Clin Rheumatol"},{"key":"1014_CR38","doi-asserted-by":"publisher","first-page":"R95","DOI":"10.1186\/ar3370","volume":"13","author":"H Appel","year":"2011","unstructured":"Appel\u00a0H, Maier\u00a0R, Wu\u00a0P et al (2011) Analysis of IL-17(+) cells in facet joints of patients with spondyloarthritis suggests that the innate immune pathway might be of greater relevance than the Th17-mediated adaptive immune response. Arthritis Res Ther 13:R95","journal-title":"Arthritis Res Ther"},{"key":"1014_CR39","doi-asserted-by":"publisher","first-page":"955","DOI":"10.1002\/art.24389","volume":"60","author":"F Ciccia","year":"2009","unstructured":"Ciccia\u00a0F, Bombardieri\u00a0M, Principato\u00a0A et al (2009) Overexpression of interleukin-23, but not interleukin-17, as an immunologic signature of subclinical intestinal inflammation in ankylosing spondylitis. Arthritis Rheum 60:955\u2013965","journal-title":"Arthritis Rheum"},{"key":"1014_CR40","doi-asserted-by":"publisher","first-page":"1069","DOI":"10.1038\/nm.2817","volume":"18","author":"JP Sherlock","year":"2012","unstructured":"Sherlock\u00a0JP, Joyce-Shaikh\u00a0B, Turner\u00a0SP et al (2012) IL-23 induces spondyloarthropathy by acting on ROR-\u03b3t+ CD3+CD4-CD8- entheseal resident T cells. Nat Med 18:1069\u20131076","journal-title":"Nat Med"},{"key":"1014_CR41","doi-asserted-by":"publisher","first-page":"1755","DOI":"10.1002\/art.38638","volume":"66","author":"H Benham","year":"2014","unstructured":"Benham\u00a0H, Rehaume\u00a0LM, Hasnain\u00a0SZ et al (2014) Interleukin-23 mediates the intestinal response to microbial \u03b2\u20111,3\u2011glucan and the development of spondyloarthritis pathology in SKG mice. Arthritis Rheumatol 66:1755\u20131767","journal-title":"Arthritis Rheumatol"},{"key":"1014_CR42","doi-asserted-by":"publisher","first-page":"2359","DOI":"10.1084\/jem.180.6.2359","volume":"180","author":"JD Taurog","year":"1994","unstructured":"Taurog\u00a0JD, Richardson\u00a0JA, Croft\u00a0JT et al (1994) The germfree state prevents development of gut and joint inflammatory disease in HLA-B27 transgenic rats. J\u00a0Exp Med 180:2359\u20132364","journal-title":"J Exp Med"},{"key":"1014_CR43","doi-asserted-by":"publisher","first-page":"1614","DOI":"10.1136\/annrheumdis-2016-211064","volume":"76","author":"M Breban","year":"2017","unstructured":"Breban\u00a0M, Tap\u00a0J, Leboime\u00a0A et\u00a0al (2017) Faecal microbiota study reveals specific dysbiosis in spondyloarthritis. Ann Rheum Dis 76:1614\u20131622","journal-title":"Ann Rheum Dis"},{"key":"1014_CR44","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1002\/art.39802","volume":"69","author":"RY Tito","year":"2017","unstructured":"Tito\u00a0RY, Cypers\u00a0H, Joossens\u00a0M et\u00a0al (2017) Brief report: dialister as a\u00a0microbial marker of disease activity in spondyloarthritis. Arthritis Rheumatol 69:114\u2013121","journal-title":"Arthritis Rheumatol"},{"key":"1014_CR45","doi-asserted-by":"publisher","first-page":"2124","DOI":"10.1136\/annrheumdis-2015-208902","volume":"75","author":"E Gracey","year":"2016","unstructured":"Gracey\u00a0E, Qaiyum\u00a0Z, Almaghlouth\u00a0I et al (2016) IL\u20117 primes IL-17 in mucosal-associated invariant T (MAIT) cells, which contribute to the Th17-axis in ankylosing spondylitis. Ann Rheum Dis 75:2124\u20132132","journal-title":"Ann Rheum Dis"},{"key":"1014_CR46","doi-asserted-by":"publisher","first-page":"1566","DOI":"10.1136\/annrheumdis-2019-215349","volume":"78","author":"Z Qaiyum","year":"2019","unstructured":"Qaiyum\u00a0Z, Gracey\u00a0E, Yao\u00a0Y, Inman\u00a0RD (2019) Integrin and transcriptomic profiles identify a\u00a0distinctive synovial CD8+ T cell subpopulation in spondyloarthritis. Ann Rheum Dis 78:1566","journal-title":"Ann Rheum Dis"},{"key":"1014_CR47","doi-asserted-by":"publisher","first-page":"1745","DOI":"10.1053\/gast.2000.20173","volume":"119","author":"E May","year":"2000","unstructured":"May\u00a0E, M\u00e4rker-Hermann\u00a0E, Wittig\u00a0BM et al (2000) Identical T\u2011cell expansions in the colon mucosa and the synovium of a\u00a0patient with enterogenic spondyloarthropathy. Gastroenterology 119:1745\u20131755","journal-title":"Gastroenterology"},{"key":"1014_CR48","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1093\/ecco-jcc\/jjv238","volume":"10","author":"M Severs","year":"2016","unstructured":"Severs\u00a0M, van Erp\u00a0SJ, van der Valk\u00a0ME, Dutch Initiative on Crohn and Colitis et al (2016) Smoking is associated with extra-intestinal manifestations in inflammatory bowel disease. J\u00a0Crohns Colitis 10:455\u2013461","journal-title":"J Crohns Colitis"},{"key":"1014_CR49","doi-asserted-by":"publisher","first-page":"1431","DOI":"10.1055\/s-0034-1385199","volume":"52","author":"JC Prei\u00df","year":"2014","unstructured":"Prei\u00df\u00a0JC, Bokemeyer\u00a0B, Buhr\u00a0HJ et al (2014) Aktualisierte S3-Leitlinie \u2013 \u201eDiagnostik und Therapie des Morbus Crohn\u201c 2014. AWMF-Registrierungsnummer: 021-004. Z\u00a0Gastroenterol 52:1431\u20131484","journal-title":"Z Gastroenterol"},{"key":"1014_CR50","doi-asserted-by":"publisher","first-page":"e241","DOI":"10.1055\/a-1296-3444","volume":"58","author":"T Kucharzik","year":"2020","unstructured":"Kucharzik\u00a0T, Dignass\u00a0AU, Atreya\u00a0R et al (2020) Aktualisierte S3-Leitlinie Colitis ulcerosa\u2014Living Guideline August 2020\u2014AWMF-Registriernummer: 021-009. Z\u00a0Gastroenterol 58:e241\u2013e345","journal-title":"Z Gastroenterol"},{"key":"1014_CR51","doi-asserted-by":"publisher","first-page":"485","DOI":"10.1111\/apt.14419","volume":"47","author":"S Tadbiri","year":"2018","unstructured":"Tadbiri\u00a0S, Peyrin-Biroulet\u00a0L, Serrero\u00a0M, Getaid Observ-IBD study group et al (2018) Impact of vedolizumab therapy on extra-intestinal manifestations in patients with inflammatory bowel disease: a\u00a0multicentre cohort study nested in the Observ-IBD cohort. Aliment Pharmacol Ther 47:485\u2013493","journal-title":"Aliment Pharmacol Ther"},{"key":"1014_CR52","doi-asserted-by":"publisher","first-page":"2325","DOI":"10.1002\/1529-0131(199911)42:11<2325::AID-ANR10>3.0.CO;2-C","volume":"42","author":"DO Clegg","year":"1999","unstructured":"Clegg\u00a0DO, Reda\u00a0DJ, Abdellatif\u00a0M (1999) Comparison of sulfasalazine and placebo for the treatment of axial and peripheral articular manifestations of the seronegative spondylarthropathies: a\u00a0department of veterans affairs cooperative study. Arthritis Rheum 42:2325\u20132329","journal-title":"Arthritis Rheum"},{"key":"1014_CR53","doi-asserted-by":"publisher","first-page":"1821","DOI":"10.1016\/S0140-6736(00)03239-6","volume":"356","author":"F Van den Bosch","year":"2000","unstructured":"Van den Bosch\u00a0F, Kruithof\u00a0E, De Vos\u00a0M et al (2000) Crohn\u2019s disease associated with spondyloarthropathy: effect of TNF-alpha blockade with infliximab on articular symptoms. Lancet 356:1821\u20131822","journal-title":"Lancet"},{"key":"1014_CR54","doi-asserted-by":"publisher","first-page":"1664","DOI":"10.1136\/ard.2003.012450","volume":"63","author":"S Generini","year":"2004","unstructured":"Generini\u00a0S, Giacomelli\u00a0R, Fedi\u00a0R et\u00a0al (2004) Infliximab in spondyloarthropathy associated with Crohn\u2019s disease: an open study on the efficacy of inducing and maintaining remission of musculoskeletal and gut manifestations. Ann Rheum Dis 63:1664\u20131669","journal-title":"Ann Rheum Dis"},{"key":"1014_CR55","doi-asserted-by":"publisher","first-page":"7139","DOI":"10.3748\/wjg.v23.i39.7139","volume":"23","author":"MM Luchetti","year":"2017","unstructured":"Luchetti\u00a0MM, Benfaremo\u00a0D, Ciccia\u00a0F et al (2017) Adalimumab efficacy in enteropathic spondyloarthritis: a 12-mo observational multidisciplinary study. World J Gastroenterol 23:7139\u20137149","journal-title":"World J Gastroenterol"},{"key":"1014_CR56","doi-asserted-by":"publisher","first-page":"1088","DOI":"10.1053\/gast.2001.28674","volume":"121","author":"WJ Sandborn","year":"2001","unstructured":"Sandborn\u00a0WJ, Hanauer\u00a0SB, Katz\u00a0S et al (2001) Etanercept for active Crohn\u2019s disease: a\u00a0randomized, double-blind, placebo-controlled trial. Gastroenterology 121:1088\u20131094","journal-title":"Gastroenterology"},{"key":"1014_CR57","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1136\/ard.62.1.74","volume":"62","author":"H Marzo-Ortega","year":"2003","unstructured":"Marzo-Ortega\u00a0H, McGonagle\u00a0D, O\u2019Connor\u00a0P et al (2003) Efficacy of etanercept for treatment of Crohn\u2019s related spondyloarthritis but not colitis. Ann Rheum Dis 62:74\u201376","journal-title":"Ann Rheum Dis"},{"key":"1014_CR58","doi-asserted-by":"publisher","first-page":"1519","DOI":"10.1056\/NEJMoa1203572","volume":"367","author":"WJ Sandborn","year":"2012","unstructured":"Sandborn\u00a0WJ, Gasink\u00a0C, Gao\u00a0LL et\u00a0al (2012) Ustekinumab induction and maintenance therapy in refractory Crohn\u2019s disease. N\u00a0Engl J Med 367:1519\u20131528","journal-title":"N Engl J Med"},{"key":"1014_CR59","doi-asserted-by":"publisher","first-page":"1201","DOI":"10.1056\/NEJMoa1900750","volume":"381","author":"BE Sands","year":"2019","unstructured":"Sands\u00a0BE, Sandborn\u00a0WJ, Panaccione\u00a0R et\u00a0al (2019) Ustekinumab as induction and maintenance therapy for ulcerative colitis. N\u00a0Engl J Med 381:1201\u20131214","journal-title":"N Engl J Med"},{"key":"1014_CR60","doi-asserted-by":"publisher","first-page":"258","DOI":"10.1002\/art.40728","volume":"71","author":"A Deodhar","year":"2019","unstructured":"Deodhar\u00a0A, Gensler\u00a0LS, Sieper\u00a0J et al (2019) Three multicenter, randomized, double-blind, placebo-controlled studies evaluating the efficacy and safety of ustekinumab in axial spondyloarthritis. Arthritis Rheumatol 71:258\u2013270","journal-title":"Arthritis Rheumatol"},{"key":"1014_CR61","doi-asserted-by":"publisher","first-page":"488","DOI":"10.1016\/j.immuni.2015.06.024","volume":"43","author":"X Song","year":"2015","unstructured":"Song\u00a0X, Dai\u00a0D, He\u00a0X, Zhu\u00a0S, Yao\u00a0Y, Gao\u00a0H, Wang\u00a0J, Qu\u00a0F, Qiu\u00a0J, Wang\u00a0H et al (2015) Growth factor FGF2 cooperates with Interleukin-17 to repair intestinal epithelial damage. Immunity 43:488\u2013501","journal-title":"Immunity"},{"issue":"5","key":"1014_CR62","doi-asserted-by":"publisher","first-page":"e0233781","DOI":"10.1371\/journal.pone.0233781","volume":"15","author":"J Burisch","year":"2020","unstructured":"Burisch\u00a0J, Eigner\u00a0W, Schreiber\u00a0S et al (2020) Risk for development of inflammatory bowel disease under inhibition of interleukin 17: a systematic review and meta-analysis. PLoS ONE 15(5):e233781","journal-title":"PLoS ONE"}],"container-title":["Zeitschrift f\u00fcr Rheumatologie"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00393-021-01014-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00393-021-01014-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00393-021-01014-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,4]],"date-time":"2021-08-04T14:04:35Z","timestamp":1628085875000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00393-021-01014-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5,27]]},"references-count":62,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2021,8]]}},"alternative-id":["1014"],"URL":"https:\/\/doi.org\/10.1007\/s00393-021-01014-2","relation":{},"ISSN":["0340-1855","1435-1250"],"issn-type":[{"value":"0340-1855","type":"print"},{"value":"1435-1250","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,5,27]]},"assertion":[{"value":"16 April 2021","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 May 2021","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Einhaltung ethischer Richtlinien"}},{"value":"Gem\u00e4\u00df den Richtlinien des Springer Medizin Verlags werden Autoren und Wissenschaftliche Leitung im Rahmen der Manuskripterstellung und Manuskriptfreigabe aufgefordert, eine vollst\u00e4ndige Erkl\u00e4rung zu ihren finanziellen und nichtfinanziellen Interessen abzugeben.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}},{"value":"<b>E.\u00a0M\u00e4rker-Hermann<\/b>: A.\u00a0Finanzielle Interessen: Referentenhonorar oder Kostenerstattung als passiver Teilnehmer: Bis vor 5\u00a0Jahren: AbbVie, Pfizer, Janssen, Roche, MedUpdate. Danach nicht mehr pers\u00f6nlich, sondern nur Vertr\u00e4ge zwischen Veranstaltern und Arbeitgeber Helios Kliniken. \u2013\u00a0Bezahlter Berater\/interner Schulungsreferent\/Gehaltsempf\u00e4nger o.\u202f\u00c4.: Boehringer Ingelheim, Fresenius Kabi. Beides nicht pers\u00f6nlich, sondern nur \u00fcber Vertr\u00e4ge mit dem Arbeitgeber Helios Kliniken.\u00a0\u2013 B.\u00a0Nichtfinanzielle Interessen: Klinikdirektorin, Helios Kliniken, Helios HSK Wiesbaden, angestellte Chef\u00e4rztin, Klinik Innere Medizin\u00a0IV, Rheumatologie, klinische Immunologie, Nephrologie | Mitgliedschaften: Deutsche Gesellschaft f\u00fcr Rheumatologie (wiss. Beirat), Deutsche Gesellschaft f\u00fcr Innere Medizin (Ausschuss), Berufsverband der Rheumatologen, Walter-Siegenthaler Gesellschaft (Pr\u00e4sidium).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Autoren"}},{"value":"Die vollst\u00e4ndige Erkl\u00e4rung zum Interessenkonflikt der Wissenschaftlichen Leitung finden Sie am Kurs der zertifizierten Fortbildung auf ExternalRef removed.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Wissenschaftliche Leitung"}},{"value":"erkl\u00e4rt, dass f\u00fcr die Publikation dieser CME-Fortbildung keine Sponsorengelder an den Verlag flie\u00dfen.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Der Verlag"}},{"value":"F\u00fcr diesen Beitrag wurden von den Autoren keine Studien an Menschen oder Tieren durchgef\u00fchrt. F\u00fcr die aufgef\u00fchrten Studien gelten die jeweils dort angegebenen ethischen Richtlinien. F\u00fcr Bildmaterial oder anderweitige Angaben innerhalb des Manuskripts, \u00fcber die Patienten zu identifizieren sind, liegt von ihnen und\/oder ihren gesetzlichen Vertretern eine schriftliche Einwilligung vor.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Der Verlag"}}]}}