{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T22:08:53Z","timestamp":1793052533819,"version":"4.5.0"},"reference-count":18,"publisher":"Springer Science and Business Media LLC","issue":"S1","license":[{"start":{"date-parts":[[2021,7,21]],"date-time":"2021-07-21T00:00:00Z","timestamp":1626825600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2021,7,21]],"date-time":"2021-07-21T00:00:00Z","timestamp":1626825600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Z Rheumatol"],"published-print":{"date-parts":[[2023,1]]},"DOI":"10.1007\/s00393-021-01051-x","type":"journal-article","created":{"date-parts":[[2021,7,21]],"date-time":"2021-07-21T09:03:02Z","timestamp":1626858182000},"page":"68-73","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Polyautoimmunity in systemic lupus erythematosus: secondary Sjogren syndrome","Polyautoimmunit\u00e4t bei systemischem Lupus erythematosus: sekund\u00e4res Sj\u00f6gren-Syndrom"],"prefix":"10.1007","volume":"82","author":[{"given":"Cristiana","family":"Sieiro Santos","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clara","family":"Moriano Morales","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina","family":"\u00c1lvarez Castro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elvira","family":"D\u00edez\u00a0Alvarez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,7,21]]},"reference":[{"key":"1051_CR1","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1016\/j.jaut.2012.05.008","volume":"39","author":"MJ Amador-Patarroyo","year":"2012","unstructured":"Amador-Patarroyo\u00a0MJ, Arbelaez\u00a0JG, Mantilla\u00a0RD et al (2012) Sjogren\u2019s syndrome at the crossroad of polyautoimmunity. J\u00a0Autoimmun 39:199\u2013205","journal-title":"J Autoimmun"},{"issue":"4","key":"1051_CR2","doi-asserted-by":"publisher","first-page":"246","DOI":"10.1016\/j.semarthrit.2006.08.007","volume":"36","author":"M Ramos-Casals","year":"2007","unstructured":"Ramos-Casals\u00a0M, Brito-Zer\u00f3n\u00a0P, Font\u00a0J (2007) The overlap of Sj\u00f6gren\u2019s syndrome with other systemic autoimmune diseases. Semin Arthritis Rheum 36(4):246\u2013255","journal-title":"Semin Arthritis Rheum"},{"key":"1051_CR3","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1016\/S0889-857X(21)00731-6","volume":"18","author":"J Harley","year":"1992","unstructured":"Harley\u00a0J, Scofield\u00a0H, Reichlin\u00a0M (1992) Anti-Ro in Sj\u00f6gren\u2019s syndrome and systemic lupus erythematosus. Rheum Dis Clin North Am 18:337\u2013358","journal-title":"Rheum Dis Clin North Am"},{"key":"1051_CR4","doi-asserted-by":"publisher","first-page":"1143","DOI":"10.3899\/jrheum.090804","volume":"3","author":"A Baer","year":"2010","unstructured":"Baer\u00a0A, Maynard\u00a0J, Shaikh\u00a0F et\u00a0al (2010) Secondary Sj\u00f6gren\u2019s syndrome in systemic lupus erythematosus defines a\u00a0distinct disease subset. J\u00a0Rheumatol 3:1143\u20131149","journal-title":"J Rheumatol"},{"key":"1051_CR5","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1191\/096120398678920046","volume":"7","author":"JC Nossent","year":"1998","unstructured":"Nossent\u00a0JC, Swaak\u00a0A (1998) Systemic lupus erythematosus VII: frequency and impact of secondary Sj\u00f6gren\u2019s syndrome. Lupus 7:231\u2013234","journal-title":"Lupus"},{"key":"1051_CR6","doi-asserted-by":"publisher","first-page":"882","DOI":"10.1002\/art.20093","volume":"50","author":"M Manoussakis","year":"2004","unstructured":"Manoussakis\u00a0M, Georgopoulou\u00a0C, Zintzaras\u00a0E et\u00a0al (2004) Sj\u00f6gren\u2019s syndrome associated with systemic lupus erythematosus. Arthritis Rheum 50:882\u2013891","journal-title":"Arthritis Rheum"},{"key":"1051_CR7","first-page":"201","volume":"17","author":"A Andonopoulos","year":"1990","unstructured":"Andonopoulos\u00a0A, Skopouli\u00a0F, Dimou\u00a0G et\u00a0al (1990) Sj\u00f6gren syndrome in systemic lupus erythematosus. J\u00a0Rheumatol 17:201\u2013204","journal-title":"J Rheumatol"},{"key":"1051_CR8","doi-asserted-by":"publisher","first-page":"1103","DOI":"10.1136\/ard.60.12.1103","volume":"60","author":"J Gilboe","year":"2001","unstructured":"Gilboe\u00a0J, Kvien\u00a0T, Uhlig\u00a0T et\u00a0al (2001) Sicca symptoms and secondary Sj\u00f6gren\u2019s syndrome in systemic lupus erythematosus: comparison with rheumatoid arthritis and correlation with disease variables. Ann Rheum Dis 60:1103\u20131109","journal-title":"Ann Rheum Dis"},{"key":"1051_CR9","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1007\/s10067-007-0720-0","volume":"27","author":"H Feng","year":"2008","unstructured":"Feng\u00a0H, Qing\u00a0D, Wang\u00a0Q et\u00a0al (2008) Clinical and laboratory profiles of SLE associated with Sj\u00f6gren\u2019s syndrome in China: a study of 542 patients. Clin Rheumatol 27:339\u2013343","journal-title":"Clin Rheumatol"},{"key":"1051_CR10","doi-asserted-by":"publisher","first-page":"924","DOI":"10.1016\/j.humimm.2006.06.006","volume":"67","author":"A Szanto","year":"2006","unstructured":"Szanto\u00a0A, Szodoray\u00a0P, Kiss\u00a0E et\u00a0al (2006) Clinical, serologic and genetic profiles of patients with associated Sj\u00f6gren\u2019s syndrome and systemic lupus erythematosus. Hum Immunol 67:924\u2013930","journal-title":"Hum Immunol"},{"key":"1051_CR11","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1002\/art.1780230107","volume":"23","author":"H Moutsopoulos","year":"1980","unstructured":"Moutsopoulos\u00a0H, Klippel\u00a0J, Pavlidis\u00a0N et\u00a0al (1980) Correlative histologic and serologic findings of sicca syndrome in patients with systemic lupus erythematosus. Arthritis Rheum 23:36\u201340","journal-title":"Arthritis Rheum"},{"key":"1051_CR12","doi-asserted-by":"publisher","first-page":"882","DOI":"10.1002\/art.20093","volume":"50","author":"NM Menelaos","year":"2004","unstructured":"Menelaos\u00a0NM, Chryssoula\u00a0G, Elias\u00a0Z et\u00a0al (2004) Sjogren\u2019s syndrome associated with systemic lupus erythematosus: Clinical and analytic profiles and comparison with primary Sj\u00f6gren\u2019s syndrome. Arthritis Rheum 50:882\u2013891","journal-title":"Arthritis Rheum"},{"key":"1051_CR13","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1007\/s10067-007-0720-0","volume":"27","author":"HF Pan","year":"2008","unstructured":"Pan\u00a0HF, Ye\u00a0DQ, Wang\u00a0Q et\u00a0al (2008) Clinical and laboratory profiles of systemic lupus erythematosus associated with Sj\u00f6gren syndrome in China: a\u00a0study of 542\u00a0patients. Clin Rheumatol 27:339","journal-title":"Clin Rheumatol"},{"key":"1051_CR14","first-page":"166","volume":"61","author":"H Jonsson","year":"1986","unstructured":"Jonsson\u00a0H, Nived\u00a0O, Sturfelt\u00a0G, Norberg\u00a0R (1986) Symptomatic secondary Sj\u00f6gren\u2019s syndrome in patients with systemic lupus erythematosus (SLE). Relation to anti-SS\u2011A and anti-SS\u2011B autoantibodies. Scand J Rheumatol Suppl 61:166\u2013169","journal-title":"Scand J Rheumatol Suppl"},{"issue":"3","key":"1051_CR15","doi-asserted-by":"publisher","first-page":"419","DOI":"10.1016\/j.rdc.2016.03.002","volume":"42","author":"A Fayyaz","year":"2016","unstructured":"Fayyaz\u00a0A, Kurien\u00a0BT, Scofield\u00a0RH (2016) Autoantibodies in Sj\u00f6gren\u2019s syndrome. Rheum Dis Clin North Am 42(3):419\u2013434","journal-title":"Rheum Dis Clin North Am"},{"key":"1051_CR16","doi-asserted-by":"publisher","first-page":"e451","DOI":"10.1016\/j.lpm.2012.05.022","volume":"41","author":"AG Tzioufas","year":"2012","unstructured":"Tzioufas\u00a0AG, Tatouli\u00a0IP, Moutsopoulos\u00a0HM (2012) Autoantibodies in Sj\u00f6gren\u2019s syndrome: clinical presentation and regulatory mechanisms. Presse Med 41:e451\u2013e460. https:\/\/doi.org\/10.1016\/j.lpm.2012.05.022","journal-title":"Presse Med"},{"issue":"4","key":"1051_CR17","doi-asserted-by":"publisher","first-page":"270","DOI":"10.1097\/00005792-200207000-00003","volume":"81","author":"M Garc\u00eda-Carrasco","year":"2002","unstructured":"Garc\u00eda-Carrasco\u00a0M, Ramos-Casals\u00a0M, Rosas\u00a0J, Pallar\u00e9s\u00a0L, CalvoAlen\u00a0J, Cervera\u00a0R, Font\u00a0J, Ingelmo\u00a0M (2002) Primary Sj\u00f6gren syndrome: clinical and immunologic disease patterns in a\u00a0cohort of 400\u00a0patients. Medicine 81(4):270\u2013280","journal-title":"Medicine"},{"issue":"5","key":"1051_CR18","doi-asserted-by":"publisher","first-page":"840","DOI":"10.1007\/s10875-011-9553-3","volume":"31","author":"C Martel","year":"2011","unstructured":"Martel\u00a0C, Gondran\u00a0G, Launay\u00a0D, Lalloue\u00a0F, Palat\u00a0S, Lambert\u00a0M et\u00a0al (2011) Active immunological profile is associated with systemic Sj\u00f6gren\u2019s syndrome. J\u00a0Clin Immunol 31(5):840\u2013847","journal-title":"J Clin Immunol"}],"container-title":["Zeitschrift f\u00fcr Rheumatologie"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00393-021-01051-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00393-021-01051-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00393-021-01051-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,13]],"date-time":"2023-01-13T16:24:02Z","timestamp":1673627042000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00393-021-01051-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7,21]]},"references-count":18,"journal-issue":{"issue":"S1","published-print":{"date-parts":[[2023,1]]}},"alternative-id":["1051"],"URL":"https:\/\/doi.org\/10.1007\/s00393-021-01051-x","relation":{},"ISSN":["0340-1855","1435-1250"],"issn-type":[{"value":"0340-1855","type":"print"},{"value":"1435-1250","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,7,21]]},"assertion":[{"value":"21 June 2021","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 July 2021","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"C.\u00a0Sieiro Santos, C.\u00a0Moriano Morales, C.\u00a0\u00c1lvarez Castro, and E.\u00a0D\u00edez Alvarez declare that they have no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The study was conducted according to the principles of the Declaration of Helsinki and approved by the institutional ethics committee of Complejo Asistencial Universitario de Le\u00f3n. <i>Patient Consent for publication:<\/i> oral and written consent was obtained from all patients.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}