{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,3]],"date-time":"2025-12-03T13:14:43Z","timestamp":1764767683934,"version":"3.46.0"},"reference-count":5,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T00:00:00Z","timestamp":1758672000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/deed.de"},{"start":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T00:00:00Z","timestamp":1758672000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/deed.de"}],"funder":[{"name":"Deutsches Rheuma-Forschungszentrum Berlin (DRFZ)"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Z Rheumatol"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title>\n                  <jats:p>Im April 2025 wurden Empfehlungen der European Alliance of Associations for Rheumatology (EULAR) zur Anwendung von Antirheumatika bei Kinderwunsch, in der Schwangerschaft und in der Stillzeit publiziert. Sie aktualisieren und ersetzen die bisherigen \u201ePoints to Consider\u201c der EULAR von 2016. Die Task Force formulierte 5 \u00fcbergreifende Prinzipien und 12\u00a0Empfehlungen f\u00fcr den Einsatz von Antirheumatika vor und w\u00e4hrend der Schwangerschaft, in der Stillzeit und bei m\u00e4nnlichen Patienten. \u00dcbergreifend wird auf die gro\u00dfe Bedeutung der effektiven Kontrolle der Krankheitsaktivit\u00e4t in Schwangerschaft und Stillzeit zum Schutz von Mutter und Kind hingewiesen. Anders als in der Version von 2016 werden Biologika, v.\u00a0a. Tumornekrosefaktorinhibitoren, als unbedenklich sowohl in der Schwangerschaft als auch in der Stillzeit eingesch\u00e4tzt. Hingegen wird gr\u00f6\u00dfere Zur\u00fcckhaltung bei der Verwendung von nichtsteroidalen Antirheumatika und Glukokortikoiden, insbesondere in h\u00f6heren Dosen und \u00fcber l\u00e4ngere Zeitr\u00e4ume, empfohlen. Neu aufgenommen wurden Empfehlungen f\u00fcr Antirheumatika bei M\u00e4nnern mit Kinderwunsch sowie zu Impfungen im S\u00e4uglingsalter nach intrauteriner Biologikaexposition. Dieses Hot Topic fasst die EULAR Empfehlungen f\u00fcr die deutsche Rheumatologie zusammen.<\/jats:p>","DOI":"10.1007\/s00393-025-01727-8","type":"journal-article","created":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T08:29:06Z","timestamp":1758702546000},"page":"843-849","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["\u00dcberblick \u00fcber die neuen EULAR-Empfehlungen zur antirheumatischen Therapie bei Kinderwunsch, in der Schwangerschaft und Stillzeit","Overview of the new EULAR recommendations on antirheumatic therapy in reproduction, pregnancy and lactation"],"prefix":"10.1007","volume":"84","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0147-4112","authenticated-orcid":false,"given":"Yvette","family":"Mei\u00dfner","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frauke","family":"F\u00f6rger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,9,24]]},"reference":[{"issue":"5","key":"1727_CR1","doi-asserted-by":"publisher","first-page":"795","DOI":"10.1136\/annrheumdis-2015-208840","volume":"75","author":"C Gotestam Skorpen","year":"2016","unstructured":"Gotestam Skorpen\u00a0C, Hoeltzenbein\u00a0M, Tincani\u00a0A, Fischer-Betz\u00a0R, Elefant\u00a0E, Chambers\u00a0C, da Silva\u00a0J, Nelson-Piercy\u00a0C, Cetin\u00a0I, Costedoat-Chalumeau\u00a0N, Dolhain\u00a0R, Forger\u00a0F, Khamashta\u00a0M, Ruiz-Irastorza\u00a0G, Zink\u00a0A, Vencovsky\u00a0J, Cutolo\u00a0M, Caeyers\u00a0N, Zumbuhl\u00a0C, Ostensen\u00a0M (2016) The EULAR points to consider for use of antirheumatic drugs before pregnancy, and during pregnancy and lactation. 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Ann Rheum Dis 84(6):910\u2013926. https:\/\/doi.org\/10.1016\/j.ard.2025.02.023","journal-title":"Ann Rheum Dis"},{"key":"1727_CR3","doi-asserted-by":"publisher","DOI":"10.1016\/j.ard.2025.02.021","author":"A Pluma","year":"2025","unstructured":"Pluma\u00a0A, Hamroun\u00a0S, Ruegg\u00a0L, Cecchi\u00a0I, Kramer\u00a0M, Perez-Garcia\u00a0LF, Rivero\u00a0T, Finckh\u00a0A, Meissner\u00a0Y, Forger\u00a0F (2025) Antirheumatic drugs in reproduction, pregnancy, and lactation: a\u00a0systematic literature review informing the 2024 update of the EULAR recommendations. Ann Rheum Dis. https:\/\/doi.org\/10.1016\/j.ard.2025.02.021","journal-title":"Ann Rheum Dis"},{"issue":"11","key":"1727_CR4","doi-asserted-by":"publisher","first-page":"1524","DOI":"10.1136\/ard-2022-222641","volume":"81","author":"Y Meissner","year":"2022","unstructured":"Meissner\u00a0Y, Strangfeld\u00a0A, Molto\u00a0A, Forger\u00a0F, Wallenius\u00a0M, Costedoat-Chalumeau\u00a0N, Bjorngaard\u00a0H, Couderc\u00a0M, Flipo\u00a0RM, Guettrot-Imbert\u00a0G, Haase\u00a0I, Jakobsen\u00a0B, Koksvik\u00a0HSS, Richez\u00a0C, Sellam\u00a0J, Weiss\u00a0A, Zbinden\u00a0A, Fischer-Betz\u00a0R, EuNe Pcg (2022) Pregnancy and neonatal outcomes in women with axial spondyloarthritis: pooled data analysis from the European Network of Pregnancy Registries in Rheumatology (EuNeP). 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