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PCS und rheumatischen Erkrankungen, insbesondere Kollagenosen, zeigen eine hohe Schnittmenge von Symptomen und Biomarkern. Bislang existieren keine Biomarker, die PCS-PatientInnen mit und ohne rheumatischen Erkrankungen unterscheiden, und es gibt nur wenig Daten zur Pr\u00e4valenz rheumatischer Erkrankungen in diesem Kollektiv in Deutschland.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methode<\/jats:title>\n                    <jats:p>\n                      Basierend auf der Online-Plattform DEFEAT-Corona rekrutierten wir\n                      <jats:italic>n<\/jats:italic>\n                      \u202f=\u200980\u00a0Menschen mit PCS-Erkrankung ohne zuvor gesicherte entz\u00fcndlich rheumatische Erkrankung (ERE) mit Interesse an rheumatologischer Abkl\u00e4rung. Wir analysierten PCS- und Rheuma-typische Beschwerden. Zudem erfolgten umfassende Laboranalysen.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Ergebnisse<\/jats:title>\n                    <jats:p>\n                      Bei 6,25\u202f% (\n                      <jats:italic>n<\/jats:italic>\n                      \u202f=\u20095) der PCS-PatientInnen bestand Verdacht auf ERE oder konnte eine ERE gesichert werden. Auch bei den\n                      <jats:italic>n<\/jats:italic>\n                      \u202f=\u200975\u00a0PCS-PatientInnen ohne ERE zeigte sich ein hoher \u00dcberschneidungsgrad von PCS- und rheumatischen Beschwerden. Die Entz\u00fcndungsparameter CRP und BSG waren bei PCS-PatientInnen mit Verdacht auf eine ERE im Vergleich zu anderen PCS-Betroffenen signifikant h\u00f6her und waren bei PCS-PatientInnen mit Verdacht auf ERE signifikant h\u00e4ufiger oberhalb des Normbereichs.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Schlussfolgerung<\/jats:title>\n                    <jats:p>Unsere Arbeit illustriert den hohen \u00dcberschneidungsgrad von PCS- mit Rheumasymptomen, ohne dass sich ein weiterf\u00fchrender Verdacht auf eine ERE ergibt. Das Risiko f\u00fcr ERE k\u00f6nnte bei PCS erh\u00f6ht sein, ein PCS ohne zus\u00e4tzliche Risikofaktoren, wie z.\u202fB. erh\u00f6htes CRP oder Arthritis, rechtfertigt jedoch aus Sicht der AutorInnen keine generelle Vorstellung bei einer RheumatologIn in der klinischen Routine. Diese Empfehlung sollte in gr\u00f6\u00dferen Studien weiter untersucht werden.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00393-025-01735-8","type":"journal-article","created":{"date-parts":[[2025,10,14]],"date-time":"2025-10-14T15:45:10Z","timestamp":1760456710000},"page":"188-199","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Entz\u00fcndlich rheumatische Erkrankungen bei PatientInnen mit Post-COVID-Syndrom","Inflammatory rheumatic diseases in patients with post-COVID syndrome"],"prefix":"10.1007","volume":"85","author":[{"given":"N.","family":"Kippenbroek","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"St\u00f6lting","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Schr\u00f6der","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Wetzke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Happle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Dopfer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Schmachtenberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Witte","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Steffens","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Mikuteit","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"M\u00fcller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. 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G.M.N.\u00a0Behrens erhielt F\u00f6rderung durch den Europ\u00e4ischen Fonds f\u00fcr regionale Entwicklung ZW7-85151373, A.\u00a0Dopfer-Jablonka ebenso (ZAM5-87006761). Keine Finanzierer spielten eine Rolle bei der Konzeption und Durchf\u00fchrung der Analysen, dem Verfassen des Manuskripts und\/oder der Entscheidung, das Manuskript zur Ver\u00f6ffentlichung einzureichen. Keiner der AutorInnen erhielt eine Verg\u00fctung von einem Pharmaunternehmen oder einer anderen Agentur, um die Publikation zu verfassen. Den AutorInnen war der Zugang zu den Daten der Studie nicht verwehrt, und sie \u00fcbernehmen die volle Verantwortung, sie zur Ver\u00f6ffentlichung einzureichen. N.\u00a0Kippenbroek, A.\u00a0St\u00f6lting, D.\u00a0Schr\u00f6der, M.\u00a0Wetzke, C.\u00a0Happle, C.\u00a0Dopfer, T.\u00a0Schmachtenberg, T.\u00a0Witte, S.\u00a0Steffens, M.\u00a0Mikuteit und F.\u00a0M\u00fcller geben an, dass kein Interessenkonflikt besteht.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}},{"value":"Die Zustimmung der Ethikkommissionen aller teilnehmenden Zentren wurde eingeholt (Medizinische Hochschule Hannover #9948_BO_K_2021, Universit\u00e4tsmedizin G\u00f6ttingen \u201e15\/8\/22 \u00dc\u201c). Zum Schutz und der Wahrung der pers\u00f6nlichen Rechte der Studienteilnehmenden wurden die in der Deklaration von Helsinki beschriebenen Grunds\u00e4tze beachtet. Die Studie wurde dem Deutschen Register f\u00fcr klinische Studien unter der Nummer DRKS00026007 gemeldet.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}}]}}