{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T15:21:18Z","timestamp":1786980078531,"version":"build-2736575974"},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2015,8,15]],"date-time":"2015-08-15T00:00:00Z","timestamp":1439596800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Hong Kong General Research Fund","award":["260712"],"award-info":[{"award-number":["260712"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Nutr"],"published-print":{"date-parts":[[2016,8]]},"DOI":"10.1007\/s00394-015-1012-0","type":"journal-article","created":{"date-parts":[[2015,8,14]],"date-time":"2015-08-14T03:22:18Z","timestamp":1439522538000},"page":"1963-1972","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Chronic black tea extract consumption improves endothelial function in ovariectomized rats"],"prefix":"10.1007","volume":"55","author":[{"given":"Fung Ping","family":"Leung","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lai Ming","family":"Yung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ching Yuen","family":"Ngai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wai San","family":"Cheang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao Yu","family":"Tian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chi Wai","family":"Lau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhen Yu","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhao-Xiang","family":"Bian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoqiang","family":"Yao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2015,8,15]]},"reference":[{"key":"1012_CR1","doi-asserted-by":"crossref","first-page":"1861","DOI":"10.1001\/jama.1991.03460140089033","volume":"265","author":"E Barrett-Connor","year":"1991","unstructured":"Barrett-Connor E, Bush TL (1991) Estrogen and coronary heart disease in women. JAMA 265:1861\u20131867","journal-title":"JAMA"},{"key":"1012_CR2","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1056\/NEJM199109123251102","volume":"325","author":"MJ Stampfer","year":"1991","unstructured":"Stampfer MJ, Colditz GA, Willett WC, Manson JE, Rosner B, Speizer FE, Hennekens CH (1991) Postmenopausal estrogen therapy and cardiovascular disease. Ten-year follow-up from the nurses\u2019 health study. N Engl J Med 325:756\u2013762","journal-title":"N Engl J Med"},{"key":"1012_CR3","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1016\/S0140-6736(97)08233-0","volume":"350","author":"Collaborative Group on Hormonal Factors in Breast Cancer","year":"1997","unstructured":"Collaborative Group on Hormonal Factors in Breast Cancer (1997) Breast cancer and hormone replacement therapy: collaborative reanalysis of data from 51 epidemiological studies of 52,705 women with breast cancer and 108,411 women without breast cancer. Lancet 350:1047\u20131059","journal-title":"Lancet"},{"key":"1012_CR4","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/S0140-6736(03)14065-2","volume":"362","author":"Million Women Study Collaborators","year":"2003","unstructured":"Million Women Study Collaborators (2003) Breast cancer and hormone-replacement therapy in the Million Women Study. Lancet 362:419\u2013427","journal-title":"Lancet"},{"key":"1012_CR5","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1136\/bmj.297.6647.519","volume":"297","author":"A Paganini-Hill","year":"1988","unstructured":"Paganini-Hill A, Ross RK, Henderson BE (1988) Postmenopausal oestrogen treatment and stroke: a prospective study. BMJ 297:519\u2013522","journal-title":"BMJ"},{"key":"1012_CR6","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1001\/jama.280.7.605","volume":"280","author":"S Hulley","year":"1998","unstructured":"Hulley S, Grady D, Bush T, Furberg C, Herrington D, Riggs B, Vittinghoff E (1998) Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. Heart and Estrogen\/progestin Replacement Study (HERS) Research Group. JAMA 280:605\u2013613","journal-title":"JAMA"},{"issue":"3","key":"1012_CR7","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1001\/jama.288.3.321","volume":"288","author":"JE Rossouw","year":"2002","unstructured":"Rossouw JE, Anderson GL, Prentice RL, LaCroix AZ, Kooperberg C, Stefanick ML, Jackson RD, Beresford SA, Howard BV, Johnson KC, Kotchen JM, Ockene J, Writing Group for the Women\u2019s Health Initiative Investigators (2002) Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results From the Women\u2019s Health Initiative randomized controlled trial. JAMA 288(3):321\u2013333","journal-title":"JAMA"},{"issue":"14","key":"1012_CR8","doi-asserted-by":"crossref","first-page":"1701","DOI":"10.1001\/jama.291.14.1775","volume":"291","author":"GL Anderson","year":"2004","unstructured":"Anderson GL, Limacher M, Assaf AR, Bassford T, Beresford SA, Black H, Bonds D, Brunner R, Brzyski R, Caan B, Chlebowski R, Curb D, Gass M, Hays J, Heiss G, Hendrix S, Howard BV, Hsia J, Hubbell A, Jackson R, Johnson KC, Judd H, Kotchen JM, Kuller L, LaCroix AZ, Lane D, Langer RD, Lasser N, Lewis CE, Manson J, Margolis K, Ockene J, O\u2019Sullivan MJ, Phillips L, Prentice RL, Ritenbaugh C, Robbins J, Rossouw JE, Sarto G, Stefanick ML, Van Horn L, Wactawski-Wende J, Wallace R, Wassertheil-Smoller S, Committee Women\u2019s Health Initiative Steering (2004) Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: the Women\u2019s Health Initiative randomized controlled trial. JAMA 291(14):1701\u20131712","journal-title":"JAMA"},{"key":"1012_CR9","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1016\/j.mam.2010.09.004","volume":"31","author":"JM Hodgson","year":"2010","unstructured":"Hodgson JM, Croft KD (2010) Tea flavonoids and cardiovascular health. Mol Asp Med 31:495\u2013502","journal-title":"Mol Asp Med"},{"key":"1012_CR10","doi-asserted-by":"crossref","first-page":"1554S","DOI":"10.1093\/jn\/138.8.1554S","volume":"138","author":"D Grassi","year":"2008","unstructured":"Grassi D, Aggio A, Onori L, Croce G, Tiberti S, Ferri C, Ferri L, Desideri G (2008) Tea, flavonoids, and nitric oxide-mediated vascular reactivity. J Nutr 138:1554S\u20131560S","journal-title":"J Nutr"},{"key":"1012_CR11","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1007\/s10787-008-8022-y","volume":"16","author":"LM Yung","year":"2008","unstructured":"Yung LM, Leung FP, Wong WT, Tian XY, Yung LH, Chen ZY, Yao XQ, Huang Y (2008) Tea polyphenols benefit vascular function. Inflammopharmacology 16:230\u2013234","journal-title":"Inflammopharmacology"},{"key":"1012_CR12","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.abb.2010.03.015","volume":"501","author":"L Arab","year":"2010","unstructured":"Arab L, Liebeskind DS (2010) Tea, flavonoids and stroke in man and mouse. Arch Biochem Biophys 501:31\u201336","journal-title":"Arch Biochem Biophys"},{"key":"1012_CR13","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1007\/s00395-008-0759-3","volume":"104","author":"M Lorenz","year":"2009","unstructured":"Lorenz M, Urban J, Engelhardt U, Baumann G, Stangl K, Stangl V (2009) Green and black tea are equally potent stimuli of NO production and vasodilation: new insights into tea ingredients involved. Basic Res Cardiol 104:100\u2013110","journal-title":"Basic Res Cardiol"},{"key":"1012_CR14","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1007\/s00394-012-0425-2","volume":"52","author":"LM Yung","year":"2013","unstructured":"Yung LM, Tian XY, Wong WT, Leung FP, Yung LH, Chen ZY, Lau CW, Vanhoutte PM, Yao X, Huang Y (2013) Chronic cranberry juice consumption restores cholesterol profiles and improves endothelial function in ovariectomized rats. Eur J Nutr 52:1145\u20131155","journal-title":"Eur J Nutr"},{"key":"1012_CR15","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1161\/CIRCRESAHA.111.262170","volume":"110","author":"XY Tian","year":"2012","unstructured":"Tian XY, Wong WT, Xu A, Lu Y, Zhang Y, Wang L, Cheang WS, Wang Y, Yao X, Huang Y (2012) Uncoupling protein-2 protects endothelial function in diet-induced obese mice. Circ Res 110:1211\u20131216","journal-title":"Circ Res"},{"key":"1012_CR16","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1161\/ATVBAHA.113.301938","volume":"34","author":"WS Cheang","year":"2014","unstructured":"Cheang WS, Tian XY, Wong WT, Lau CW, Lee SS, Chen ZY, Yao X, Wang N, Huang Y (2014) Metformin protects endothelial function in diet-induced obese mice by inhibition of endoplasmic reticulum stress through 5\u2032 adenosine monophosphate-activated protein kinase-peroxisome proliferator-activated receptor \u03b4 pathway. Arterioscler Thromb Vasc Biol 34:830\u2013836","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"1012_CR17","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1161\/ATVBAHA.113.302696","volume":"34","author":"Y Zhang","year":"2014","unstructured":"Zhang Y, Liu J, Tian XY, Wong WT, Chen Y, Wang L, Luo J, Cheang WS, Lau CW, Kwan KM, Wang N, Yao X, Huang Y (2014) Inhibition of bone morphogenic protein 4 restores endothelial function in db\/db diabetic mice. Arterioscler Thromb Vasc Biol 34:152\u2013159","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"4","key":"1012_CR18","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1016\/j.bcp.2003.10.002","volume":"67","author":"Y Huang","year":"2004","unstructured":"Huang Y, Wong CM, Lau CW, Yao X, Tsang SY, Su YL, Chen ZY (2004) Inhibition of nitric oxide\/cyclic GMP-mediated relaxation by purified flavonoids, baicalin and baicalein, in rat aortic rings. Biochem Pharmacol 67(4):787\u2013794","journal-title":"Biochem Pharmacol"},{"key":"1012_CR19","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1097\/FJC.0b013e3181d7671c","volume":"55","author":"WT Wong","year":"2010","unstructured":"Wong WT, Wong SL, Tian XT, Huang Y (2010) Endothelial dysfunction: the common consequence in diabetes and hypertension. J Cardiovasc Pharmacol 55:300\u2013307","journal-title":"J Cardiovasc Pharmacol"},{"key":"1012_CR20","doi-asserted-by":"crossref","first-page":"11F","DOI":"10.1016\/S0002-9149(01)02218-4","volume":"90","author":"P Ganz","year":"2002","unstructured":"Ganz P (2002) Vasomotor and vascular effects of hormone replacement therapy. Am J Cardiol 90:11F\u201316F","journal-title":"Am J Cardiol"},{"key":"1012_CR21","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1161\/01.CIR.104.2.151","volume":"104","author":"SJ Duffy","year":"2001","unstructured":"Duffy SJ, Keaney JF Jr, Holbrook M, Gokce N, Swerdloff PL, Frei B, Vita JA (2001) Short- and long-term black tea consumption reverses endothelial dysfunction in patients with coronary artery disease. Circulation 104:151\u2013156","journal-title":"Circulation"},{"key":"1012_CR22","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1042\/cs1020195","volume":"102","author":"JM Hodgson","year":"2002","unstructured":"Hodgson JM, Puddey IB, Burke V, Watts GF, Beilin LJ (2002) Regular ingestion of black tea improves brachial artery vasodilator function. Clin Sci (Lond) 102:195\u2013201","journal-title":"Clin Sci (Lond)"},{"key":"1012_CR23","doi-asserted-by":"crossref","first-page":"e17437","DOI":"10.1371\/journal.pone.0017437","volume":"6","author":"LM Yung","year":"2011","unstructured":"Yung LM, Wong WT, Tian XY, Leung FP, Yung LH, Chen ZY, Yao X, Lau CW, Huang Y (2011) Inhibition of renin-angiotensin system reverses endothelial dysfunction and oxidative stress in estrogen deficient rats. PLoS One 6:e17437","journal-title":"PLoS One"},{"key":"1012_CR24","doi-asserted-by":"crossref","first-page":"e80892","DOI":"10.1371\/journal.pone.0080892","volume":"8","author":"IF Caliman","year":"2013","unstructured":"Caliman IF, Lamas AZ, Dalpiaz PL, MedeirosAR Abreu GR, Figueiredo SG, Gusm\u00e3o LN, Andrade TU, Bissoli NS (2013) Endothelial relaxation mechanisms and oxidative stress are restored by atorvastatin therapy in ovariectomized rats. PLoS One 8:e80892","journal-title":"PLoS One"},{"key":"1012_CR25","doi-asserted-by":"crossref","first-page":"2258","DOI":"10.1161\/01.CIR.101.19.2258","volume":"101","author":"A Virdis","year":"2000","unstructured":"Virdis A, Ghiadoni L, Pinto S, Lombardo M, Petraglia F, Gennazzani A, Buralli S (2000) Mechanisms responsible for endothelial dysfunction associated with acute estrogen deprivation in normotensive women. Circulation 101:2258\u20132263","journal-title":"Circulation"},{"key":"1012_CR26","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1161\/01.RES.87.10.840","volume":"87","author":"H Cai","year":"2000","unstructured":"Cai H, Harrison DG (2000) Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress. Circ Res 87:840\u2013844","journal-title":"Circ Res"},{"issue":"Suppl","key":"1012_CR27","first-page":"18S","volume":"75","author":"RA Lobo","year":"1990","unstructured":"Lobo RA (1990) Cardiovascular implications of estrogen replacement therapy. Obstet Gynecol 75(Suppl):18S\u201325S","journal-title":"Obstet Gynecol"},{"issue":"1","key":"1012_CR28","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1161\/01.ATV.11.1.23","volume":"11","author":"RS Kushwaha","year":"1991","unstructured":"Kushwaha RS, Lewis DS, Carey KD, McGill HC Jr (1991) Effects of estrogen and progesterone on plasma lipoproteins and experimental atherosclerosis in the baboon (Papio sp.). Arterioscler Thromb 11(1):23\u201331","journal-title":"Arterioscler Thromb"},{"key":"1012_CR29","doi-asserted-by":"crossref","first-page":"23","DOI":"10.3181\/00379727-217-44201","volume":"217","author":"MT Subbiah","year":"1998","unstructured":"Subbiah MT (1998) Mechanisms of cardioprotection by estrogens. Proc Soc Exper Biol Med 217:23\u201329","journal-title":"Proc Soc Exper Biol Med"},{"issue":"10","key":"1012_CR30","doi-asserted-by":"crossref","first-page":"3298S","DOI":"10.1093\/jn\/133.10.3298S","volume":"133","author":"MJ Davies","year":"2003","unstructured":"Davies MJ, Judd JT, Baer DJ, Clevidence BA, Paul DR, Edwards AJ, Wiseman SA, Muesing RA, Chen SC (2003) Black tea consumption reduces total and LDL cholesterol in mildly hypercholesterolemic adults. J Nutr 133(10):3298S\u20133302S","journal-title":"J Nutr"}],"container-title":["European Journal of Nutrition"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00394-015-1012-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00394-015-1012-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00394-015-1012-0","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,29]],"date-time":"2019-08-29T06:38:26Z","timestamp":1567060706000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00394-015-1012-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,8,15]]},"references-count":30,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2016,8]]}},"alternative-id":["1012"],"URL":"https:\/\/doi.org\/10.1007\/s00394-015-1012-0","relation":{},"ISSN":["1436-6207","1436-6215"],"issn-type":[{"value":"1436-6207","type":"print"},{"value":"1436-6215","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,8,15]]}}}