{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T06:36:37Z","timestamp":1790836597376,"version":"4.1.0"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2016,11,17]],"date-time":"2016-11-17T00:00:00Z","timestamp":1479340800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/100005136","name":"KRAFT foods","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005136","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Univerity of Oslo"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Nutr"],"published-print":{"date-parts":[[2018,3]]},"DOI":"10.1007\/s00394-016-1336-4","type":"journal-article","created":{"date-parts":[[2016,11,17]],"date-time":"2016-11-17T07:12:15Z","timestamp":1479366735000},"page":"533-544","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":41,"title":["Coffee and oxidative stress: a human intervention study"],"prefix":"10.1007","volume":"57","author":[{"given":"Sergey","family":"Shaposhnikov","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Hatzold","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naouale El","family":"Yamani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip Mark","family":"Stavro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yolanda","family":"Lorenzo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Dusinska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Astrid","family":"Reus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wilrike","family":"Pasman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Collins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2016,11,17]]},"reference":[{"key":"1336_CR1","first-page":"141","volume-title":"Coffee. Emerging health effects and disease prevention","author":"NV Matusheshki","year":"2012","unstructured":"Matusheshki NV, Bidel S, Tuomilehto J (2012) Coffee and type 2 diabetes risk. In: Chu Y-F (ed) Coffee. Emerging health effects and disease prevention. Wiley-Blackwell, Oxford, pp 141\u2013179"},{"key":"1336_CR2","first-page":"111","volume-title":"Coffee. Emerging health effects and disease prevention","author":"J-W Lim","year":"2012","unstructured":"Lim J-W, Tan E-K (2012) Coffee and Parkinson\u2019s disease. In: Chu Y-F (ed) Coffee. Emerging health effects and disease prevention. Wiley-Blackwell, Oxford, pp 111\u2013122"},{"key":"1336_CR3","first-page":"97","volume-title":"Coffee. Emerging health effects and disease prevention","author":"J Lindsay","year":"2012","unstructured":"Lindsay J, Carmichael P-H, Kr\u00f6ger E, Laurin D (2012) Coffee and Alzheimer\u2019s disease\u2014epidemiologic evidence. In: Chu Y-F (ed) Coffee. Emerging health effects and disease prevention. Wiley-Blackwell, Oxford, pp 97\u2013110"},{"key":"1336_CR4","first-page":"123","volume-title":"Coffee. Emerging health effects and disease prevention","author":"P Muriel","year":"2012","unstructured":"Muriel P, Arauz J (2012) Coffee and liver health. In: Chu Y-F (ed) Coffee. Emerging health effects and disease prevention. Wiley-Blackwell, Oxford, pp 123\u2013139"},{"key":"1336_CR5","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1002\/9783527626588.ch32","volume-title":"Chemoprevention of cancer and DNA damage by dietary factors","author":"G Faustmann","year":"2009","unstructured":"Faustmann G, Cavin C, Nersesyan A, Knasm\u00fcller S (2009) Chemopreventive properties of coffee and its constituents. In: Knasm\u00fcller S, DeMarini DM, Johnson I, Gerh\u00e4user C (eds) Chemoprevention of cancer and DNA damage by dietary factors. Wiley-VCH, Weinheim, pp 579\u2013594"},{"key":"1336_CR6","series-title":"Gluthione transferases and gamma-glutamyl transpeptidases","first-page":"307","volume-title":"Methods in enzymology","author":"WW Huber","year":"2005","unstructured":"Huber WW, Parzefall W (2005) Modification of N-acetyltransferases and glutathione S-transferases by coffee components: possible relevance for cancer risk. In: Sies Helmut, Packer Lester (eds) Methods in enzymology, vol 401, Gluthione transferases and gamma-glutamyl transpeptidasesAcademic Press, Massachusetts, pp 307\u2013341"},{"key":"1336_CR7","doi-asserted-by":"crossref","first-page":"1230","DOI":"10.1016\/j.fct.2007.09.094","volume":"46","author":"WW Huber","year":"2008","unstructured":"Huber WW, Rossmanith W, Grusch M, Haslinger E, Prustomersky S, Peter-V\u00f6r\u00f6smarty B, Parzefall W, Scharf G, Schulte-Hermann R (2008) Effects of coffee and its chemopreventive components kahweol and cafestol on cytochrome P450 and sulfotransferase in rat liver. Food Chem Toxicol 46:1230\u20131238","journal-title":"Food Chem Toxicol"},{"key":"1336_CR8","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1016\/j.fct.2007.09.099","volume":"46","author":"C Cavin","year":"2008","unstructured":"Cavin C, Marin-Kuan M, Langou\u00ebt S, Bezen\u00e7on C, Guignard G, Verguet C, Piguet D, Holzh\u00e4user D, Cornaz R, Schilter B (2008) Induction of Nrf2-mediated cellular defenses and alteration of phase I activities as mechanisms of chemoprotective effects of coffee in the liver. Food Chem Toxicol 46:1239\u20131248","journal-title":"Food Chem Toxicol"},{"key":"1336_CR9","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1016\/j.taap.2007.09.018","volume":"226","author":"LG Higgins","year":"2008","unstructured":"Higgins LG, Cavin C, Itoh K, Yamamoto M, Hayes JD (2008) Induction of cancer chemopreventive enzymes by coffee is mediated by transcription factor Nrf2. Evidence that the coffee-specific diterpenes cafestol and kahweol confer protection against acrolein. Toxicol Appl Pharmacol 226:328\u2013337","journal-title":"Toxicol Appl Pharmacol"},{"key":"1336_CR10","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/S0098-2997(02)00017-1","volume":"23","author":"HR Griffiths","year":"2002","unstructured":"Griffiths HR, M\u00f6ller L, Bartosz G, Bast A, Bertoni-Freddari C, Collins A, Cooke M, Coolen S, Haenen G, Hoberg A-M, Loft S, Lunec J, Olinski R, Parry J, Pompella A, Poulsen H, Verhagen H, Astley S (2002) Biomarkers. Mole Asp Med 23:101\u2013208","journal-title":"Mole Asp Med"},{"key":"1336_CR11","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1385\/MB:26:3:249","volume":"26","author":"AR Collins","year":"2004","unstructured":"Collins AR (2004) The comet assay for DNA damage and repair. Mol Biotechnol 26:249\u2013261","journal-title":"Mol Biotechnol"},{"key":"1336_CR12","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.toxlet.2010.02.017","volume":"195","author":"S Shaposhnikov","year":"2010","unstructured":"Shaposhnikov S, Azqueta A, Henriksson S, Meier S, Gaiv\u00e3o I, Huskisson NH, Smart A, Brunborg G, Nilsson M, Collins AR (2010) Twelve-gel slide format optimised for comet assay and fluorescent in situ hybridisation. Toxicol Lett 195:31\u201334","journal-title":"Toxicol Lett"},{"key":"1336_CR13","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1016\/S0278-6915(02)00055-8","volume":"40","author":"M Dusinska","year":"2002","unstructured":"Dusinska M, Vallov\u00e1 B, Urs\u00ednyov\u00e1 M, Hlad\u00edkov\u00e1 V, Smolkov\u00e1 B, Ws\u00f3lov\u00e1 L, Raslov\u00e1 K, Collins AR (2002) DNA damage and antioxidants: fluctuation through the year in a central European population group. Food Chem Toxicol 40:1119\u20131123","journal-title":"Food Chem Toxicol"},{"key":"1336_CR14","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/S0921-8777(97)00057-8","volume":"407","author":"P M\u00f8ller","year":"1998","unstructured":"M\u00f8ller P, Knudsen LE, Frentz G, Dybdahl M, Wallin H, Nex\u00f8 BA (1998) Seasonal variation of DNA damage and repair in patients with non-melanoma skin cancer and referents with and without psoriasis. Mutat Res 407:25\u201334","journal-title":"Mutat Res"},{"key":"1336_CR15","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1097\/01.hjh.0000166828.94699.1d","volume":"23","author":"M Noordzij","year":"2005","unstructured":"Noordzij M, Uitervaal CSPM, Arends L, Kok F, Grobbee D, Geleijnse JM (2005) Blood pressure response to chronic intake of coffee and caffeine: a meta-analysis of randomized controlled trials. J Hypertens 23:921\u201392814","journal-title":"J Hypertens"},{"key":"1336_CR16","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/j.freeradbiomed.2004.11.025","volume":"38","author":"J Mursu","year":"2005","unstructured":"Mursu J, Voutilainen S, Nurmi T, Alfthan G, Virtanen JK, Rissanen TH, Happonen P, Nyyss\u00f6nen K, Kaikkonen J, Salonen R, Salonen JT (2005) The effects of coffee consumption on lipid peroxidation and plasma total homocysteine concentrations: a clinical trial. Free Radic Biol Med 38:527\u2013534","journal-title":"Free Radic Biol Med"},{"key":"1336_CR17","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/j.mrfmmm.2005.04.016","volume":"591","author":"H Steinkellner","year":"2005","unstructured":"Steinkellner H, Hoelzl C, Uhl M, Cavin C, Haidinger G, Gsur A, Schmid R, Kundi M, Bichler J, Knasm\u00fcller S (2005) Coffee consumption induces GSTP in plasma and protects lymphocytes against (\u00b1)-anti-benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide induced DNA-damage: results of controlled human intervention trials. Mutat Res Fundam Mole Mech Mutagen 591:264\u2013275","journal-title":"Mutat Res Fundam Mole Mech Mutagen"},{"key":"1336_CR18","doi-asserted-by":"crossref","first-page":"1428","DOI":"10.1016\/j.fct.2007.02.001","volume":"45","author":"J Bichler","year":"2007","unstructured":"Bichler J, Cavin C, Simic T, Chakraborty A, Ferk F, Hoelzl C, Schulte-Hermann R, Kundi M, Haidinger G, Angelis K, Knasm\u00fcller S (2007) Coffee consumption protects human lymphocytes against oxidative and 3-amino-1-methyl-5H-pyrido[4,3-b]indole acetate (Trp-P-2) induced DNA-damage: results of an experimental study with human volunteers. Food Chem Toxicol 45:1428\u20131436","journal-title":"Food Chem Toxicol"},{"key":"1336_CR19","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.mrfmmm.2010.08.003","volume":"692","author":"M Misik","year":"2010","unstructured":"Misik M, Hoelzl C, Wagner KH, Cavin C, Moser B, Kundi M, Simic T, Elbling L, Kager N, Ferk F, Ehrlich V, Nersesyan A, Dusinska M, Schilter B, Knasm\u00fcller S (2010) Impact of paper filtered coffee on oxidative DNA-damage: results of a clinical trial. Mutat Res Fundam Mole Mech Mutagen 692:42\u201348","journal-title":"Mutat Res Fundam Mole Mech Mutagen"},{"key":"1336_CR20","doi-asserted-by":"crossref","first-page":"1722","DOI":"10.1002\/mnfr.201000048","volume":"54","author":"C Hoelzl","year":"2010","unstructured":"Hoelzl C, Knasm\u00fcller S, Wagner KH, Elbling L, Huber W, Kager N, Ferk F, Ehrlich V, Nersesyan A, Neubauer O, Desmarchelier A, Marin-Kuan M, Delatour T, Verguet C, Bezen\u00e7on C, Besson A, Grathwohl D, Simic T, Kundi M, Schilter B, Cavin C (2010) Instant coffee with high chlorogenic acid levels protects humans against oxidative damage of macromolecules. Mol Nutr Food Res 54:1722\u20131733","journal-title":"Mol Nutr Food Res"},{"key":"1336_CR21","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1016\/j.freeradbiomed.2006.04.001","volume":"41","author":"P M\u00f8ller","year":"2006","unstructured":"M\u00f8ller P, Loft S (2006) Dietary antioxidants and beneficial effect on oxidatively damaged DNA. Free Radic Biol Med 41:388\u2013415","journal-title":"Free Radic Biol Med"},{"key":"1336_CR22","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/S0921-8777(00)00049-5","volume":"461","author":"I Schulz","year":"2000","unstructured":"Schulz I, Mahler HC, Boiteux S, Epe B (2000) Oxidative DNA base damage induced by singlet oxygen and photosensitization: recognition by repair endonucleases and mutagenicity. Mutat Res DNA Repair 461:145\u2013156","journal-title":"Mutat Res DNA Repair"}],"container-title":["European Journal of Nutrition"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00394-016-1336-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00394-016-1336-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00394-016-1336-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,3,10]],"date-time":"2018-03-10T04:29:00Z","timestamp":1520656140000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00394-016-1336-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11,17]]},"references-count":22,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2018,3]]}},"alternative-id":["1336"],"URL":"https:\/\/doi.org\/10.1007\/s00394-016-1336-4","relation":{},"ISSN":["1436-6207","1436-6215"],"issn-type":[{"value":"1436-6207","type":"print"},{"value":"1436-6215","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,11,17]]}}}