{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T12:12:14Z","timestamp":1789647134821,"version":"4.0.0"},"reference-count":48,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2020,5,6]],"date-time":"2020-05-06T00:00:00Z","timestamp":1588723200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2020,5,6]],"date-time":"2020-05-06T00:00:00Z","timestamp":1588723200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/100011199","name":"FP7 Ideas: European Research Council","doi-asserted-by":"crossref","award":["FP7\/2007-2013"],"award-info":[{"award-number":["FP7\/2007-2013"]}],"id":[{"id":"10.13039\/100011199","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100011103","name":"Sixth Framework Programme","doi-asserted-by":"publisher","award":["007036"],"award-info":[{"award-number":["007036"]}],"id":[{"id":"10.13039\/100011103","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004966","name":"Fifth Framework Programme","doi-asserted-by":"publisher","award":["QLRT-2001-00389"],"award-info":[{"award-number":["QLRT-2001-00389"]}],"id":[{"id":"10.13039\/501100004966","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Fifth Framework Programme","award":["QLK1-CT-200230582"],"award-info":[{"award-number":["QLK1-CT-200230582"]}]},{"DOI":"10.13039\/100010661","name":"Horizon 2020 Framework Programme","doi-asserted-by":"crossref","award":["633595"],"award-info":[{"award-number":["633595"]}],"id":[{"id":"10.13039\/100010661","id-type":"DOI","asserted-by":"crossref"}]},{"name":"European Research Council","award":["322605"],"award-info":[{"award-number":["322605"]}]},{"DOI":"10.13039\/100011262","name":"FP7 Food, Agriculture and Fisheries, Biotechnology","doi-asserted-by":"crossref","award":["289346"],"award-info":[{"award-number":["289346"]}],"id":[{"id":"10.13039\/100011262","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Nutr"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Purpose<\/jats:title>\n                <jats:p>We aimed to characterize the association of dietary sugar intake with blood lipids and glucose-related markers in childhood.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Data from the multicentric European Childhood Obesity Project Trial were used. Three-day weighed dietary records were obtained at 8\u00a0years of age along with serum concentrations of triglycerides, total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol (HDL-C), glucose, and insulin. Total sugar intake comprised all mono- and disaccharides; different sugar sources were defined. Linear regression models were applied to investigate the cross-sectional association of total sugar intake with blood lipids and glucose-related markers with adjustment for total energy intake using the residual method.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Data were available for 325 children. Children consumed on average 332\u00a0kcal (SD 110) and 21% (SD 6) of energy from total sugar. In an energy-adjusted model, an increase of 100\u00a0kcal from total sugar per day was significantly associated with a <jats:italic>z<\/jats:italic> score HDL-C decrease (\u2212\u00a00.14; 95% CI \u2212\u00a00.01, \u2212\u00a00.27; <jats:italic>p<\/jats:italic> value\u2009=\u20090.031). Concerning different food groups of total sugar intake, 100\u00a0kcal total sugar from sweetened beverages was negatively associated with <jats:italic>z<\/jats:italic> score HDL-C (\u2212\u00a01.67; 95% CI \u2212\u00a00.42, \u2212\u00a02.91; <jats:italic>p<\/jats:italic> value\u2009=\u20090.009), while total sugar from milk products was positively related to <jats:italic>z<\/jats:italic> score HDL-C (1.38, 95% CI 0.03, 2.72; <jats:italic>p<\/jats:italic> value\u2009=\u20090.045). None of the other blood lipids or glucose-related markers showed a significant relationship with total sugar intake.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Increasing dietary total sugar intake in children, especially from sweetened beverages, was associated with unfavorable effects on HDL-C, which might increase the long-term risk for dyslipidemia and cardiovascular disease.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Clinical trial registry<\/jats:title>\n                <jats:p>ClinicalTrials.gov Identifier: NCT00338689; Registered: June 19, 2006. URL: <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/clinicaltrials.gov\/ct2\/show\/NCT00338689?term=NCT00338689&amp;rank=1\">https:\/\/clinicaltrials.gov\/ct2\/show\/NCT00338689?term=NCT00338689&amp;rank=1<\/jats:ext-link>.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00394-020-02229-w","type":"journal-article","created":{"date-parts":[[2020,5,6]],"date-time":"2020-05-06T08:06:00Z","timestamp":1588752360000},"page":"435-442","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Influence of total sugar intake on metabolic blood markers at 8\u00a0years of age in the Childhood Obesity Project"],"prefix":"10.1007","volume":"60","clinical-trial-number":[{"clinical-trial-number":"nct00338689","registry":"10.18810\/clinical-trials-gov"}],"author":[{"given":"Nicole","family":"Aumueller","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dariusz","family":"Gruszfeld","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kinga","family":"Gradowska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joaqu\u00edn","family":"Escribano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalia","family":"Ferr\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7oise","family":"Martin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pascale","family":"Poncelet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elvira","family":"Verduci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alice","family":"ReDionigi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Berthold","family":"Koletzko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veit","family":"Grote","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,5,6]]},"reference":[{"key":"2229_CR1","unstructured":"Organization WH (2018) World Health Statistics 2018: Monitoring health for the SDGs, sustainable development goals"},{"issue":"Suppl 2","key":"2229_CR2","doi-asserted-by":"publisher","first-page":"S27","DOI":"10.1097\/00005344-199321002-00006","volume":"21","author":"WB Kannel","year":"1993","unstructured":"Kannel WB (1993) Hypertension as a risk factor for cardiac events\u2014epidemiologic results of long-term studies. J Cardiovasc Pharmacol 21(Suppl 2):S27\u201337","journal-title":"J Cardiovasc Pharmacol"},{"issue":"23","key":"2229_CR3","doi-asserted-by":"publisher","first-page":"1650","DOI":"10.1056\/nejm199806043382302","volume":"338","author":"GS Berenson","year":"1998","unstructured":"Berenson GS, Srinivasan SR, Bao W, Newman WP 3rd, Tracy RE, Wattigney WA (1998) Association between multiple cardiovascular risk factors and atherosclerosis in children and young adults. The Bogalusa Heart Study. N Engl J Med 338(23):1650\u20131656. https:\/\/doi.org\/10.1056\/nejm199806043382302","journal-title":"N Engl J Med"},{"issue":"3 Pt 1","key":"2229_CR4","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1542\/peds.113.3.475","volume":"113","author":"JM Sorof","year":"2004","unstructured":"Sorof JM, Lai D, Turner J, Poffenbarger T, Portman RJ (2004) Overweight, ethnicity, and the prevalence of hypertension in school-aged children. Pediatrics 113(3 Pt 1):475\u2013482","journal-title":"Pediatrics"},{"issue":"1","key":"2229_CR5","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1097\/MOL.0b013e32835a7ed4","volume":"24","author":"M Juonala","year":"2013","unstructured":"Juonala M, Viikari JS, Raitakari OT (2013) Main findings from the prospective Cardiovascular Risk in Young Finns Study. Curr Opin Lipidol 24(1):57\u201364. https:\/\/doi.org\/10.1097\/MOL.0b013e32835a7ed4","journal-title":"Curr Opin Lipidol"},{"issue":"10c","key":"2229_CR6","doi-asserted-by":"publisher","first-page":"3l","DOI":"10.1016\/S0002-9149(02)02953-3","volume":"90","author":"GS Berenson","year":"2002","unstructured":"Berenson GS (2002) Childhood risk factors predict adult risk associated with subclinical cardiovascular disease. The Bogalusa Heart Study. Am J Cardiol 90(10c):3l\u20137l","journal-title":"Am J Cardiol"},{"issue":"1","key":"2229_CR7","doi-asserted-by":"publisher","first-page":"e189","DOI":"10.1542\/peds.2006-1801","volume":"120","author":"EM Haney","year":"2007","unstructured":"Haney EM, Huffman LH, Bougatsos C, Freeman M, Steiner RD, Nelson HD (2007) Screening and treatment for lipid disorders in children and adolescents: systematic evidence review for the US Preventive Services Task Force. Pediatrics 120(1):e189\u2013214. https:\/\/doi.org\/10.1542\/peds.2006-1801","journal-title":"Pediatrics"},{"issue":"11","key":"2229_CR8","doi-asserted-by":"publisher","first-page":"1546","DOI":"10.1161\/01.CIR.103.11.1546","volume":"103","author":"HC McGill Jr","year":"2001","unstructured":"McGill HC Jr, McMahan CA, Zieske AW, Malcom GT, Tracy RE, Strong JP (2001) Effects of nonlipid risk factors on atherosclerosis in youth with a favorable lipoprotein profile. Circulation 103(11):1546\u20131550","journal-title":"Circulation"},{"issue":"3","key":"2229_CR9","doi-asserted-by":"publisher","first-page":"753","DOI":"10.2337\/dc07-9920","volume":"30","author":"DM Nathan","year":"2007","unstructured":"Nathan DM, Davidson MB, DeFronzo RA, Heine RJ, Henry RR, Pratley R, Zinman B (2007) Impaired fasting glucose and impaired glucose tolerance: implications for care. Diabetes Care 30(3):753\u2013759. https:\/\/doi.org\/10.2337\/dc07-9920","journal-title":"Diabetes Care"},{"issue":"5","key":"2229_CR10","doi-asserted-by":"publisher","first-page":"791","DOI":"10.4158\/ep12142.ra","volume":"18","author":"S Caprio","year":"2012","unstructured":"Caprio S (2012) Development of type 2 diabetes mellitus in the obese adolescent: a growing challenge. Endocr Pract 18(5):791\u2013795. https:\/\/doi.org\/10.4158\/ep12142.ra","journal-title":"Endocr Pract"},{"issue":"10184","key":"2229_CR11","doi-asserted-by":"publisher","first-page":"1958","DOI":"10.1016\/S0140-6736(19)30041-8","volume":"393","author":"A Afshin","year":"2019","unstructured":"Afshin A, Sur PJ, Fay KA, Cornaby L, Ferrara G, Salama JS, Mullany EC, Abate KH, Abbafati C, Abebe Z (2019) Health effects of dietary risks in 195 countries, 1990\u20132017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet 393(10184):1958\u20131972","journal-title":"Lancet"},{"key":"2229_CR12","volume-title":"Guideline: sugars intake for adults and children","author":"WH Organization","year":"2015","unstructured":"Organization WH (2015) Guideline: sugars intake for adults and children. World Health Organization, Geneva"},{"key":"2229_CR13","doi-asserted-by":"publisher","DOI":"10.1007\/s00394-019-01965-y","author":"I Perrar","year":"2019","unstructured":"Perrar I, Schmitting S, Della Corte KW, Buyken AE, Alexy U (2019) Age and time trends in sugar intake among children and adolescents: results from the DONALD study. Eur J Nutr. https:\/\/doi.org\/10.1007\/s00394-019-01965-y","journal-title":"Eur J Nutr"},{"issue":"2","key":"2229_CR14","doi-asserted-by":"publisher","first-page":"330","DOI":"10.1017\/s0954422414000237","volume":"27","author":"A Wittekind","year":"2014","unstructured":"Wittekind A, Walton J (2014) Worldwide trends in dietary sugars intake. Nutr Res Rev 27(2):330\u2013345. https:\/\/doi.org\/10.1017\/s0954422414000237","journal-title":"Nutr Res Rev"},{"issue":"4","key":"2229_CR15","doi-asserted-by":"publisher","first-page":"950","DOI":"10.2337\/dc13-2085","volume":"37","author":"GA Bray","year":"2014","unstructured":"Bray GA, Popkin BM (2014) Dietary sugar and body weight: have we reached a crisis in the epidemic of obesity and diabetes? health be damned! Pour on the sugar. Diabetes Care 37(4):950\u2013956. https:\/\/doi.org\/10.2337\/dc13-2085","journal-title":"Diabetes Care"},{"issue":"1","key":"2229_CR16","doi-asserted-by":"publisher","first-page":"65","DOI":"10.3945\/ajcn.113.081521","volume":"100","author":"LA Te Morenga","year":"2014","unstructured":"Te Morenga LA, Howatson AJ, Jones RM, Mann J (2014) Dietary sugars and cardiometabolic risk: systematic review and meta-analyses of randomized controlled trials of the effects on blood pressure and lipids. Am J Clin Nutr 100(1):65\u201379. https:\/\/doi.org\/10.3945\/ajcn.113.081521","journal-title":"Am J Clin Nutr"},{"issue":"3","key":"2229_CR17","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1161\/circulationaha.110.972166","volume":"123","author":"JA Welsh","year":"2011","unstructured":"Welsh JA, Sharma A, Cunningham SA, Vos MB (2011) Consumption of added sugars and indicators of cardiovascular disease risk among US adolescents. Circulation 123(3):249\u2013257. https:\/\/doi.org\/10.1161\/circulationaha.110.972166","journal-title":"Circulation"},{"issue":"1","key":"2229_CR18","doi-asserted-by":"publisher","first-page":"46","DOI":"10.3945\/ajcn.113.076505","volume":"100","author":"KP Kell","year":"2014","unstructured":"Kell KP, Cardel MI, Bohan Brown MM, Fernandez JR (2014) Added sugars in the diet are positively associated with diastolic blood pressure and triglycerides in children. Am J Clin Nutr 100(1):46\u201352. https:\/\/doi.org\/10.3945\/ajcn.113.076505","journal-title":"Am J Clin Nutr"},{"issue":"1","key":"2229_CR19","doi-asserted-by":"publisher","first-page":"e000615","DOI":"10.1161\/jaha.113.000615","volume":"3","author":"AK Lee","year":"2014","unstructured":"Lee AK, Binongo JN, Chowdhury R, Stein AD, Gazmararian JA, Vos MB, Welsh JA (2014) Consumption of less than 10% of total energy from added sugars is associated with increasing HDL in females during adolescence: a longitudinal analysis. J Am Heart Assoc 3(1):e000615. https:\/\/doi.org\/10.1161\/jaha.113.000615","journal-title":"J Am Heart Assoc"},{"issue":"2","key":"2229_CR20","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1016\/j.jand.2012.10.020","volume":"113","author":"EC Kosova","year":"2013","unstructured":"Kosova EC, Auinger P, Bremer AA (2013) The relationships between sugar-sweetened beverage intake and cardiometabolic markers in young children. J Acad Nutr Diet 113(2):219\u2013227. https:\/\/doi.org\/10.1016\/j.jand.2012.10.020","journal-title":"J Acad Nutr Diet"},{"issue":"10","key":"2229_CR21","doi-asserted-by":"publisher","first-page":"2389","DOI":"10.3945\/jn.115.212662","volume":"145","author":"MI Van Rompay","year":"2015","unstructured":"Van Rompay MI, McKeown NM, Goodman E, Eliasziw M, Chomitz VR, Gordon CM, Economos CD, Sacheck JM (2015) Sugar-sweetened beverage intake is positively associated with baseline triglyceride concentrations, and changes in intake are inversely associated with changes in HDL cholesterol over 12 months in a multi-ethnic sample of children. J Nutr 145(10):2389\u20132395. https:\/\/doi.org\/10.3945\/jn.115.212662","journal-title":"J Nutr"},{"issue":"3","key":"2229_CR22","doi-asserted-by":"publisher","first-page":"352","DOI":"10.1016\/j.jadohealth.2014.12.001","volume":"56","author":"Z Zhang","year":"2015","unstructured":"Zhang Z, Gillespie C, Welsh JA, Hu FB, Yang Q (2015) Usual intake of added sugars and lipid profiles among the US adolescents: National Health and Nutrition Examination Survey, 2005\u20132010. J Adolesc Health 56(3):352\u2013359. https:\/\/doi.org\/10.1016\/j.jadohealth.2014.12.001","journal-title":"J Adolesc Health"},{"issue":"3","key":"2229_CR23","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1017\/s1368980012002613","volume":"16","author":"K Kondaki","year":"2013","unstructured":"Kondaki K, Grammatikaki E, Jimenez-Pavon D, De Henauw S, Gonzalez-Gross M, Sjostrom M, Gottrand F, Molnar D, Moreno LA, Kafatos A, Gilbert C, Kersting M, Manios Y (2013) Daily sugar-sweetened beverage consumption and insulin resistance in European adolescents: the HELENA (Healthy Lifestyle in Europe by Nutrition in Adolescence) Study. Public Health Nutr 16(3):479\u2013486. https:\/\/doi.org\/10.1017\/s1368980012002613","journal-title":"Public Health Nutr"},{"issue":"1","key":"2229_CR24","doi-asserted-by":"publisher","first-page":"81","DOI":"10.3945\/jn.113.182519","volume":"144","author":"J Wang","year":"2014","unstructured":"Wang J, Light K, Henderson M, O'Loughlin J, Mathieu ME, Paradis G, Gray-Donald K (2014) Consumption of added sugars from liquid but not solid sources predicts impaired glucose homeostasis and insulin resistance among youth at risk of obesity. J Nutr 144(1):81\u201386. https:\/\/doi.org\/10.3945\/jn.113.182519","journal-title":"J Nutr"},{"issue":"3","key":"2229_CR25","doi-asserted-by":"publisher","first-page":"344","DOI":"10.1038\/ejcn.2013.280","volume":"68","author":"O Androutsos","year":"2014","unstructured":"Androutsos O, Moschonis G, Mavrogianni C, Roma-Giannikou E, Chrousos GP, Kanaka-Gantenbein C, Manios Y (2014) Identification of lifestyle patterns, including sleep deprivation, associated with insulin resistance in children: the Healthy Growth Study. Eur J Clin Nutr 68(3):344\u2013349. https:\/\/doi.org\/10.1038\/ejcn.2013.280","journal-title":"Eur J Clin Nutr"},{"issue":"1","key":"2229_CR26","doi-asserted-by":"publisher","first-page":"52","DOI":"10.3109\/10408363.2015.1084990","volume":"53","author":"KL Stanhope","year":"2016","unstructured":"Stanhope KL (2016) Sugar consumption, metabolic disease and obesity: The state of the controversy AU\u2014Stanhope, Kimber L. Crit Rev Clin Lab Sci 53(1):52\u201367. https:\/\/doi.org\/10.3109\/10408363.2015.1084990","journal-title":"Crit Rev Clin Lab Sci"},{"key":"2229_CR27","doi-asserted-by":"publisher","DOI":"10.3390\/nu8110697","author":"JM Rippe","year":"2016","unstructured":"Rippe JM, Angelopoulos TJ (2016) Relationship between Added Sugars Consumption and Chronic Disease Risk Factors: Current Understanding. Nutrients. https:\/\/doi.org\/10.3390\/nu8110697","journal-title":"Nutrients"},{"issue":"4","key":"2229_CR28","doi-asserted-by":"publisher","first-page":"957","DOI":"10.2337\/dc13-2506","volume":"37","author":"R Kahn","year":"2014","unstructured":"Kahn R, Sievenpiper JL (2014) Dietary sugar and body weight: have we reached a crisis in the epidemic of obesity and diabetes? we have, but the pox on sugar is overwrought and overworked. Diabetes Care 37(4):957\u2013962. https:\/\/doi.org\/10.2337\/dc13-2506","journal-title":"Diabetes Care"},{"issue":"6","key":"2229_CR29","doi-asserted-by":"publisher","first-page":"1836","DOI":"10.3945\/ajcn.2008.27091","volume":"89","author":"European Childhood Obesity Trial Study G","year":"2009","unstructured":"European Childhood Obesity Trial Study G (2009) Lower protein in infant formula is associated with lower weight up to age 2 y: a randomized clinical trial. Am J Clin Nutr 89(6):1836\u20131845. https:\/\/doi.org\/10.3945\/ajcn.2008.27091","journal-title":"Am J Clin Nutr"},{"issue":"1","key":"2229_CR30","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1097\/MPG.0b013e3181f28d33","volume":"52","author":"S Verwied-Jorky","year":"2011","unstructured":"Verwied-Jorky S, Schiess S, Luque V, Grote V, Scaglioni S, Vecchi F, Martin F, Stolarczyk A, Koletzko B, Project ftECO (2011) Methodology for longitudinal assessment of nutrient intake and dietary habits in early childhood in a transnational multicenter study. J Pediatr Gastroenterol Nutr 52(1):96\u2013102. https:\/\/doi.org\/10.1097\/MPG.0b013e3181f28d33","journal-title":"J Pediatr Gastroenterol Nutr"},{"issue":"1","key":"2229_CR31","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1038\/ejcn.2016.206","volume":"71","author":"I Pawellek","year":"2017","unstructured":"Pawellek I, Grote V, Theurich M, Closa-Monasterolo R, Stolarczyk A, Verduci E, Xhonneux A, Koletzko B (2017) Factors associated with sugar intake and sugar sources in European children from 1 to 8 years of age. Eur J Clin Nutr 71(1):25\u201332. https:\/\/doi.org\/10.1038\/ejcn.2016.206","journal-title":"Eur J Clin Nutr"},{"key":"2229_CR32","doi-asserted-by":"crossref","unstructured":"UNESCO United Nations Educational S, Organization C (2003) International Standard Classification of Education, ISCED 1997. In: Advances in cross-national comparison: a european working book for demographic and socio-economic variables, pp 195\u2013220","DOI":"10.1007\/978-1-4419-9186-7_10"},{"issue":"1 Suppl","key":"2229_CR33","doi-asserted-by":"publisher","first-page":"S27","DOI":"10.1177\/15648265040251s104","volume":"25","author":"M de Onis","year":"2004","unstructured":"de Onis M, Onyango AW, Van den Broeck J, Chumlea WC, Martorell R (2004) Measurement and standardization protocols for anthropometry used in the construction of a new international growth reference. Food Nutr Bull 25(1 Suppl):S27\u201336. https:\/\/doi.org\/10.1177\/15648265040251s104","journal-title":"Food Nutr Bull"},{"issue":"9","key":"2229_CR34","doi-asserted-by":"publisher","first-page":"660","DOI":"10.2471\/BLT.07.043497","volume":"85","author":"M de Onis","year":"2007","unstructured":"de Onis M, Onyango AW, Borghi E, Siyam A, Nishida C, Siekmann J (2007) Development of a WHO growth reference for school-aged children and adolescents. Bull World Health Organ 85(9):660\u2013667","journal-title":"Bull World Health Organ"},{"issue":"1","key":"2229_CR35","doi-asserted-by":"publisher","first-page":"595","DOI":"10.1186\/s12889-017-4492-4","volume":"17","author":"P Schwarzfischer","year":"2017","unstructured":"Schwarzfischer P, Weber M, Gruszfeld D, Socha P, Luque V, Escribano J, Xhonneux A, Verduci E, Mariani B, Koletzko B, Grote V (2017) BMI and recommended levels of physical activity in school children. BMC Public Health 17(1):595. https:\/\/doi.org\/10.1186\/s12889-017-4492-4","journal-title":"BMC Public Health"},{"issue":"3","key":"2229_CR36","doi-asserted-by":"publisher","first-page":"1053","DOI":"10.1016\/j.clnu.2017.05.003","volume":"37","author":"D Gomes","year":"2018","unstructured":"Gomes D, Luque V, Xhonneux A, Verduci E, Socha P, Koletzko B, Berger U, Grote V (2018) A simple method for identification of misreporting of energy intake from infancy to school age: results from a longitudinal study. Clin Nutr 37(3):1053\u20131060. https:\/\/doi.org\/10.1016\/j.clnu.2017.05.003","journal-title":"Clin Nutr"},{"issue":"3","key":"2229_CR37","doi-asserted-by":"publisher","first-page":"266","DOI":"10.3945\/an.112.002030","volume":"3","author":"PJ Huth","year":"2012","unstructured":"Huth PJ, Park KM (2012) Influence of dairy product and milk fat consumption on cardiovascular disease risk: a review of the evidence. Adv Nutr 3(3):266\u2013285. https:\/\/doi.org\/10.3945\/an.112.002030","journal-title":"Adv Nutr"},{"issue":"2","key":"2229_CR38","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1111\/j.1467-789X.2006.00265.x","volume":"8","author":"M Pfeuffer","year":"2007","unstructured":"Pfeuffer M, Schrezenmeir J (2007) Milk and the metabolic syndrome. Obes Rev 8(2):109\u2013118. https:\/\/doi.org\/10.1111\/j.1467-789X.2006.00265.x","journal-title":"Obes Rev"},{"issue":"3","key":"2229_CR39","doi-asserted-by":"publisher","first-page":"626","DOI":"10.3349\/ymj.2013.54.3.626","volume":"54","author":"J Kim","year":"2013","unstructured":"Kim J, Hwang JY, Kim KN, Choi YJ, Chang N, Huh KB (2013) Relationship between milk and calcium intake and lipid metabolism in female patients with type 2 diabetes. Yonsei Med J 54(3):626\u2013636. https:\/\/doi.org\/10.3349\/ymj.2013.54.3.626","journal-title":"Yonsei Med J"},{"issue":"1","key":"2229_CR40","doi-asserted-by":"publisher","first-page":"5124","DOI":"10.3402\/fnr.v54i0.5124","volume":"54","author":"L Ohlsson","year":"2010","unstructured":"Ohlsson L (2010) Dairy products and plasma cholesterol levels. Food Nutr Res 54(1):5124. https:\/\/doi.org\/10.3402\/fnr.v54i0.5124","journal-title":"Food Nutr Res"},{"issue":"1","key":"2229_CR41","doi-asserted-by":"publisher","first-page":"e1","DOI":"10.1111\/ijpo.12108","volume":"12","author":"DA Loh","year":"2017","unstructured":"Loh DA, Moy FM, Zaharan NL, Jalaludin MY, Mohamed Z (2017) Sugar-sweetened beverage intake and its associations with cardiometabolic risks among adolescents. Pediatr Obes 12(1):e1\u2013e5. https:\/\/doi.org\/10.1111\/ijpo.12108","journal-title":"Pediatr Obes"},{"issue":"4","key":"2229_CR42","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1097\/MCO.0b013e328354727e","volume":"15","author":"L Tappy","year":"2012","unstructured":"Tappy L, Mittendorfer B (2012) Fructose toxicity: is the science ready for public health actions? Curr Opin Clin Nutr Metab Care 15(4):357\u2013361. https:\/\/doi.org\/10.1097\/MCO.0b013e328354727e","journal-title":"Curr Opin Clin Nutr Metab Care"},{"issue":"5","key":"2229_CR43","doi-asserted-by":"publisher","first-page":"567","DOI":"10.1038\/pr.2015.142","volume":"78","author":"C Visuthranukul","year":"2015","unstructured":"Visuthranukul C, Sirimongkol P, Prachansuwan A, Pruksananonda C, Chomtho S (2015) Low-glycemic index diet may improve insulin sensitivity in obese children. Pediatr Res 78(5):567\u2013573. https:\/\/doi.org\/10.1038\/pr.2015.142","journal-title":"Pediatr Res"},{"issue":"20","key":"2229_CR44","doi-asserted-by":"publisher","first-page":"E711","DOI":"10.1503\/cmaj.160706","volume":"189","author":"CS Tsilas","year":"2017","unstructured":"Tsilas CS, de Souza RJ, Mejia SB, Mirrahimi A, Cozma AI, Jayalath VH, Ha V, Tawfik R, Di Buono M, Jenkins AL, Leiter LA, Wolever TMS, Beyene J, Khan T, Kendall CWC, Jenkins DJA, Sievenpiper JL (2017) Relation of total sugars, fructose and sucrose with incident type 2 diabetes: a systematic review and meta-analysis of prospective cohort studies. CMAJ 189(20):E711\u2013E720. https:\/\/doi.org\/10.1503\/cmaj.160706","journal-title":"CMAJ"},{"issue":"4","key":"2229_CR45","doi-asserted-by":"publisher","first-page":"873s","DOI":"10.1093\/ajcn\/78.4.873S","volume":"78","author":"SK Fried","year":"2003","unstructured":"Fried SK, Rao SP (2003) Sugars, hypertriglyceridemia, and cardiovascular disease. Am J Clin Nutr 78(4):873s\u2013880s. https:\/\/doi.org\/10.1093\/ajcn\/78.4.873S","journal-title":"Am J Clin Nutr"},{"issue":"11\u201312","key":"2229_CR46","doi-asserted-by":"publisher","first-page":"1044","DOI":"10.1016\/j.nut.2010.02.014","volume":"26","author":"L Tappy","year":"2010","unstructured":"Tappy L, Le KA, Tran C, Paquot N (2010) Fructose and metabolic diseases: new findings, new questions. Nutrition 26(11\u201312):1044\u20131049. https:\/\/doi.org\/10.1016\/j.nut.2010.02.014","journal-title":"Nutrition"},{"key":"2229_CR47","doi-asserted-by":"publisher","DOI":"10.1007\/s00394-019-02107-0","author":"N Aumueller","year":"2019","unstructured":"Aumueller N, Gruszfeld D, Gradowska K, Escribano J, Ferre N, Rousseaux D, Hoyos J, Verduci E, ReDionigi A, Koletzko B, Grote V (2019) Associations of sugar intake with anthropometrics in children from ages 2 until 8 years in the EU Childhood Obesity Project. Eur J Nutr. https:\/\/doi.org\/10.1007\/s00394-019-02107-0","journal-title":"Eur J Nutr"},{"issue":"8","key":"2229_CR48","first-page":"1455E","volume":"15","author":"Authority EFS","year":"2018","unstructured":"Authority EFS (1455E) Outcome of the public consultation on a draft protocol for the Scientific Opinion on dietary sugars. EFSA Support Publ 15(8):1455E","journal-title":"EFSA Support Publ"}],"container-title":["European Journal of Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00394-020-02229-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00394-020-02229-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00394-020-02229-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,10]],"date-time":"2021-08-10T13:56:08Z","timestamp":1628603768000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00394-020-02229-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5,6]]},"references-count":48,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,2]]}},"alternative-id":["2229"],"URL":"https:\/\/doi.org\/10.1007\/s00394-020-02229-w","relation":{},"ISSN":["1436-6207","1436-6215"],"issn-type":[{"value":"1436-6207","type":"print"},{"value":"1436-6215","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,5,6]]},"assertion":[{"value":"30 September 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 March 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 May 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}