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Forty-five chronic (\u2265\u20091\u00a0week) randomised controlled trials assessing CVD risk factors including endothelial (dys)function, blood pressure (BP), blood lipids and inflammatory biomarkers were included.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Investigated interventions reported improvements in endothelial function (<jats:italic>n<\/jats:italic>\u2009=\u20098), inflammatory biomarkers and lipid status (<jats:italic>n<\/jats:italic>\u2009=\u200914), and BP (<jats:italic>n<\/jats:italic>\u2009=\u200910). Berries including juice of barberry, cranberry, grape, pomegranate, powder of blueberry, grape, raspberry and freeze-dried strawberry significantly reduced SBP by 3.68\u00a0mmHg (95% CI \u2212\u00a06.79 to \u2212\u00a00.58; <jats:italic>P\u2009<\/jats:italic>=\u20090.02) and DBP by 1.52\u00a0mmHg (95% CI \u2212\u00a02.87 to \u2212\u00a00.18, <jats:italic>P<\/jats:italic>\u2009=\u20090.04). In subgroup analysis, these associations were limited to cranberry juice (SBP by 1.52\u00a0mmHg [95% CI \u2212\u00a02.97 to \u2212\u00a00.07; <jats:italic>P<\/jats:italic>\u2009=\u20090.05], DBP by 1.78\u00a0mmHg [95% CI \u2212\u00a03.43 to \u2212\u00a00.12, <jats:italic>P<\/jats:italic>\u2009=\u20090.04] and cherry juice (SBP by 3.11\u00a0mmHg [95% CI \u2212\u00a04.06 to \u2212\u00a02.15; <jats:italic>P<\/jats:italic>\u2009=\u20090.02]). Berries also significantly elevated sVCAM-1 levels by 14.57\u00a0ng\/mL (85% CI 4.22 to 24.93; <jats:italic>P<\/jats:italic>\u2009=\u20090.02).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>These findings suggest that supplementing cranberry or cherry juice might contribute to an improvement in blood pressure. No other significant improvements were observed for other specified fruits. More research is warranted comparing different classes of fruit and exploring the importance of fruit processing on their cardiovascular-protective effects.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00394-020-02299-w","type":"journal-article","created":{"date-parts":[[2020,6,13]],"date-time":"2020-06-13T14:02:43Z","timestamp":1592056963000},"page":"615-639","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":58,"title":["Effects of chronic consumption of specific fruit (berries, citrus and cherries) on CVD risk factors: a systematic review and meta-analysis of randomised controlled trials"],"prefix":"10.1007","volume":"60","author":[{"given":"Yueyue","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose Lara","family":"Gallegos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Crystal","family":"Haskell-Ramsay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6014-4952","authenticated-orcid":false,"given":"John K.","family":"Lodge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,6,13]]},"reference":[{"key":"2299_CR1","volume-title":"Diet, nutrition and the prevention of chronic diseases. 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