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We declare that the results of the study are presented clearly, honestly, and without fabrication, falsification, or inappropriate data manipulation.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The manuscript does not contain clinical studies or patient data. The entire animal experiment procedures were approved by the Committee of Animal Use for Research and Teaching at The University of Hong Kong (CULATR No. 4618-18), which is fully accredited by the Association for Assessment and Accreditation of Laboratory Animal Care International (AAALAC International).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"We confirm that the manuscript has been read and approved by all named authors, and that there are no other persons who satisfied the criteria for authorship but are not listed. We further confirm that the order of authors listed in the manuscript has been approved by all of us.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}}]}}