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Virgili","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100007512","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Nutr"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Purpose<\/jats:title>\n                <jats:p>To assess the association between three different a priori dietary patterns adherence (17-item energy reduced-Mediterranean Diet (MedDiet), Trichopoulou-MedDiet and Dietary Approach to Stop Hypertension (DASH)), as well as the Protein Diet Score and kidney function decline after one year of follow-up in elderly individuals with overweight\/obesity and metabolic syndrome (MetS).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>We prospectively analyzed 5675 participants (55\u201375\u00a0years) from the PREDIMED-Plus study. At baseline and at one year, we evaluated the creatinine-based estimated glomerular filtration rate (eGFR) and food-frequency questionnaires-derived dietary scores. Associations between four categories (decrease\/maintenance and tertiles of increase) of each dietary pattern and changes in eGFR (ml\/min\/1.73m<jats:sup>2<\/jats:sup>) or\u2009\u2265\u200910% eGFR decline were assessed by fitting multivariable linear or logistic regression models, as appropriate.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Participants in the highest tertile of increase in 17-item erMedDiet Score showed higher upward changes in eGFR (<jats:italic>\u03b2<\/jats:italic>: 1.87\u00a0ml\/min\/1.73m<jats:sup>2<\/jats:sup>; 95% CI: 1.00\u20132.73) and had lower odds of\u2009\u2265\u200910% eGFR decline (OR: 0.62; 95% CI: 0.47\u20130.82) compared to individuals in the decrease\/maintenance category, while Trichopoulou-MedDiet and DASH Scores were not associated with any renal outcomes. Those in the highest tertile of increase in Protein Diet Score had greater downward changes in eGFR (<jats:italic>\u03b2<\/jats:italic>: \u2212 0.87\u00a0ml\/min\/1.73m<jats:sup>2<\/jats:sup>; 95% CI: \u2212 1.73 to \u2212 0.01) and 32% higher odds of eGFR decline (OR: 1.32; 95% CI: 1.00\u20131.75).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Among elderly individuals with overweight\/obesity and MetS, only higher upward change in the 17-item erMedDiet score adherence was associated with better kidney function after one year. However, increasing Protein Diet Score appeared to have an adverse impact on kidney health. Trial Registration Number: ISRCTN89898870 (Data of registration: 2014).<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00394-022-02838-7","type":"journal-article","created":{"date-parts":[[2022,4,2]],"date-time":"2022-04-02T19:02:31Z","timestamp":1648926151000},"page":"3095-3108","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Prospective associations between a priori dietary patterns adherence and kidney function in an elderly Mediterranean population at high cardiovascular risk"],"prefix":"10.1007","volume":"61","author":[{"given":"Cristina","family":"Valle-Hita","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9s","family":"D\u00edaz-L\u00f3pez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nerea","family":"Becerra-Tom\u00e1s","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miguel A.","family":"Mart\u00ednez-Gonz\u00e1lez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ver\u00f3nica Ruiz","family":"Garc\u00eda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dolores","family":"Corella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert","family":"Goday","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. 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ER reported receiving grants, personal fees, and nonfinancial support from the California Walnut Commission during the conduct of the study and grants, personal fees, nonfinancial support from Alexion; personal fees from Amarin; and nonfinancial support from the International Nut Council outside the submitted work. RE reported receiving grants from Instituto de Salud Carlos III and olive oil for the trial from Fundacion Patrimonio Comunal Olivarero\\during the conduct of the study and personal fees from Brewers of Europe, Fundaci\u00f3n Cerveza y Salud, Interprofesional del Aceite de Oliva, Instituto Cervantes, Pernaud Richar, Fundaci\u00f3n Dieta Mediterr\u00e1nea, Wine and Culinary International Forum; nonfinancial support from Sociedad Espa\u00f1ola de Nutrici\u00f3n and Fundaci\u00f3n Bosch y Gimpera; and grants from Uriach Laboratories outside the submitted work. XP reported receiving grants from ISCIII during the conduct of the study; receiving consulting fees from Sanofi Aventis, Amgen, and Abbott laboratories; receiving lecture personal fees from Esteve, Lacer and Rubio laboratories. All other authors have no relevant financial or non-financial interests to disclose.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The study protocol and procedures were approved according to the ethical standards of the Declaration of Helsinki by the Institutional Review Boards (IRBs) of all the participating institutions.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Written informed consent was obtained from all individual participants included in the study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"All authors have approved this manuscript for publication.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"There are restrictions on the availability of data for the PREDIMED-Plus trial, due to the signed consent agreements around data sharing, which only allow access to external researchers for studies following the project purposes. Requestors wishing to access the PREDIMED-Plus trial data used in this study can make a request to the PREDIMED-Plus trial Steering Committee chair: predimed_plus_scommitte@googlegroups.com. The request will then be passed to members of the PREDIMED-Plus Steering Committee for deliberation.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Availability of the data and materials"}},{"value":"Not applicable.","order":7,"name":"Ethics","group":{"name":"EthicsHeading","label":"Code availability"}}]}}