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In a randomly selected sub-sample of 260 children, erythrocyte thiamine diphosphate (eThDP), plasma folate and B<jats:sub>12<\/jats:sub> concentrations, and erythrocyte glutathione reductase activation coefficient (EGRac; riboflavin biomarker) were assessed at baseline and endline.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>There was no treatment effect on endline eThDP concentrations (110.6\u2009\u00b1\u20098.9\u00a0nmol\/L in MNP vs. 109.4\u2009\u00b1\u20098.9\u00a0nmol\/L in placebo group; <jats:italic>p<\/jats:italic>\u2009=\u20090.924), EGRac (1.46\u2009\u00b1\u20090.3 vs. 1.49\u2009\u00b1\u20090.3; <jats:italic>p<\/jats:italic>\u2009=\u20090.184) and B<jats:sub>12<\/jats:sub> concentrations (523.3\u2009\u00b1\u200924.6\u00a0pmol\/L vs. 515.9\u2009\u00b1\u200924.8\u00a0pmol\/L; <jats:italic>p<\/jats:italic>\u2009=\u20090.678). Likewise, the prevalence of thiamine, riboflavin, and B<jats:sub>12<\/jats:sub> deficiencies did not differ significantly between the two groups. However, endline folate concentration was significantly higher in the MNP compared to the placebo group (28.2\u2009\u00b1\u20090.8\u00a0nmol\/L vs 19.9\u2009\u00b1\u20090.8\u00a0nmol\/L, respectively; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), and correspondingly, the prevalence of folate deficiency was significantly lower in the MNP group (1.6% vs 17.4%; <jats:italic>p<\/jats:italic>\u2009=\u20090.015).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Compared to a placebo, daily MNP for 9\u00a0months increased only folate but not thiamine, riboflavin, or B<jats:sub>12<\/jats:sub> status in young Laotian children.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Trial registration<\/jats:title>\n                <jats:p>The trial was registered at <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.clinicaltrials.gov\">www.clinicaltrials.gov<\/jats:ext-link> (NCT02428647) on April 29 2015.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00394-022-02890-3","type":"journal-article","created":{"date-parts":[[2022,5,9]],"date-time":"2022-05-09T16:03:12Z","timestamp":1652112192000},"page":"3423-3435","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Daily supplementation of a multiple micronutrient powder improves folate but not thiamine, riboflavin, or vitamin B12 status among young Laotian children: a randomized controlled trial"],"prefix":"10.1007","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8079-9702","authenticated-orcid":false,"given":"Guy-Marino","family":"Hinnouho","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniela","family":"Hampel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Setareh","family":"Shahab-Ferdows","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maxwell A.","family":"Barffour","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liadhan","family":"McAnena","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles D.","family":"Arnold","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Ryan Wessells","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sengchanh","family":"Kounnavong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lindsay H.","family":"Allen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helene","family":"McNulty","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sonja Y.","family":"Hess","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,5,9]]},"reference":[{"key":"2890_CR1","doi-asserted-by":"publisher","first-page":"1388","DOI":"10.1016\/S0140-6736(21)00394-9","volume":"397","author":"CG Victora","year":"2021","unstructured":"Victora CG, Christian P, Vidaletti LP et al (2021) Revisiting maternal and child undernutrition in low-income and middle-income countries: variable progress towards an unfinished agenda. 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