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This study aimed to investigate the association between dietary phosphorus intake and the prevalence of metabolic syndrome (MetS), as well as individual MetS components, using data from the UK National Diet and Nutrition Survey.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Data from adults aged 19 years and older were analyzed. Dietary phosphorus intake was assessed using four-day food diaries. MetS was defined based on established clinical criteria. Logistic regression models evaluated the association between phosphorus intake quintiles and MetS occurrence, adjusting for demographic, anthropometric, dietary, and lifestyle factors. Associations between phosphorus intake and individual MetS components were examined based on both total phosphorus intake and phosphorus density.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Individuals in the highest phosphorus intake quintile (&gt;\u20091509 mg\/day) exhibited a 56% lower risk of MetS compared to those in the lowest quintile (OR\u2009=\u20090.44,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009 =\u20090.0004). Higher phosphorus intake was associated with a decrease of 10.4 mg\/dl in triglyceride levels from quintile 1 to quintile 5 (mean\u2009\u00b1\u2009SD: 118.6\u2009\u00b1\u200987.5 vs. 108.2\u2009\u00b1\u200961.7,\n                      <jats:italic>p<\/jats:italic>\n                      = \u20090.002), as well as a 2.1 mmHg reduction in diastolic blood pressure (mean\u2009\u00b1\u2009SD: 74.6\u2009\u00b1\u200911.1 vs. 72.5\u2009\u00b1\u200910.7,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.001). Additionally, modest variations in HDL cholesterol and waist circumference were observed.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Higher dietary phosphorus intake was associated with a lower risk of MetS and beneficial differences in certain MetS components, supporting a potential protective role of phosphorus in metabolic health.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00394-025-03882-9","type":"journal-article","created":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T08:59:22Z","timestamp":1770886762000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Dietary phosphorus intake and its association with metabolic syndrome and its components: a cross-sectional analysis of the UK national diet and nutrition survey (NDNS)"],"prefix":"10.1007","volume":"65","author":[{"given":"R. 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The NDNS was conducted according to the guidelines laid down in the Declaration of Helsinki, and all procedures were granted ethical approval by the Cambridge South NRES Committee (reference no. 13\/EE\/0016). For ease of reference, all NDNS datasets can be accessed online through the UK Data Service: (\n                      \n                      ). Since this study is a secondary analysis of the NDNS data, additional ethical approval was not required.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}],"article-number":"48"}}