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The present study aimed to assess macronutrient intakes of people living with psoriasis in the UK and explore the relationship between their dietary sources and psoriasis severity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This was an online cross-sectional study collecting diet and psoriasis severity information from adults with psoriasis. Responses to a Food Frequency Questionnaire and the self-assessed Simplified Psoriasis Index were used to determine nutrient intakes and psoriasis severity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Relative to Dietary Reference Values, participants with psoriasis (n\u2009=\u2009257) reported an overconsumption of % energy from free sugars (median 11.2%, IQR 2.6\u201337.6) and an underconsumption of fibre (20.2 g\/day, IQR 5.9\u201344.0). Compared to participants in the lowest quartile of intake, those in the highest quartile of intake for % free sugars from beverages were more likely to report high psoriasis severity (adjusted Odds Ratio (OR) 3.85, 95% CI 1.507\u20139.831,\n                      <jats:italic>P<\/jats:italic>\n                      trend\u2009=\u20090.04), although Body Mass Index (BMI) attenuated this relationship. When fully adjusted, including BMI, elevated intakes of % protein from total meat was associated with increased odds of reporting high psoriasis severity (OR 2.47, CI 0.984\u20136.196), whilst % protein intakes from plant-based sources (OR 0.36, 0.140\u20130.915) was inversely associated with reporting high disease severity;\n                      <jats:italic>P<\/jats:italic>\n                      trends\u2009\u2264\u20090.05.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Prioritising plant-based foods may be beneficial to people living with psoriasis, but this hypothesis needs confirmation from randomised controlled trials.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00394-026-03914-y","type":"journal-article","created":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T06:33:53Z","timestamp":1771482833000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Macronutrient intakes and associations with psoriasis severity: a cross-sectional analysis of the asking people with psoriasis about lifestyle and eating (APPLE) study"],"prefix":"10.1007","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8898-8540","authenticated-orcid":false,"given":"Sylvia","family":"Zanesco","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thiviyani","family":"Maruthappu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher E. 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