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The study was conducted in accordance with the principles of the Declaration of Helsinki and its later amendments. The study protocol was approved by the following Ethics Committees: the Clinical Research Ethics Committee of Hospital Universitario La Fe (Valencia, Spain); the Clinical Research Ethics Committee of \u00c1rea Sanitaria de Gipuzkoa (Gipuzkoa, Spain); the Clinical Research Ethics Committee of Parc de Salut del Mar (Barcelona, Spain); and the Clinical Research Ethics Committee of the Principado de Asturias (Spain). The present work was additionally approved by the Clinical Research Ethics Committee of the Alicante Health Department \u2013 Hospital General (Ref.: PI2024-087, June 19, 2024).","order":2,"name":"Ethics","label":"Ethical approval","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":3,"name":"Ethics","label":"Consent for publication","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":4,"name":"Ethics","label":"Clinical trial number","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"259"}}