{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,20]],"date-time":"2025-05-20T12:32:17Z","timestamp":1747744337980},"reference-count":20,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2021,7,14]],"date-time":"2021-07-14T00:00:00Z","timestamp":1626220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2021,7,14]],"date-time":"2021-07-14T00:00:00Z","timestamp":1626220800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Universit\u00e4tsklinikum Schleswig-Holstein - Campus Kiel"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Herzschr Elektrophys"],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:sec>\n                <jats:title>Hintergrund<\/jats:title>\n                <jats:p>Reizleitungsst\u00f6rungen sind h\u00e4ufige Komplikationen der Transkatheter-Aortenklappenimplantation (TAVI). Ein Einflussfaktor ist die bisher nicht standardisiert bestimmte Implantationstiefe.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Fragestellung<\/jats:title>\n                <jats:p>Gibt es Unterschiede zwischen den anatomischen Regionen bei tiefer Implantation hinsichtlich neuer Reizleitungsst\u00f6rungen und \u00dcberleben?<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Material und Methoden<\/jats:title>\n                <jats:p>Retrospektive Kohortenanalyse, 420\u00a0Patienten mit transfemoraler TAVI mit Klappenprothesen der neuen Generation, davon 352\u00a0Patienten ohne vorbestehenden Schrittmacher f\u00fcr Analysen zur neuen Schrittmacherimplantation. Auswertung der fluoroskopisch gemessenen Implantationstiefen an der non- (NCC) und der links-koronaren Tasche (LCC) sowie der aus Patientenakten ersichtlichen Verl\u00e4ufe. Die tiefe Implantation definierte sich als tiefes Quartil der Implantationstiefe der jeweiligen Prothese. Das \u00dcberleben ergab sich aus einem 2\u2011j\u00e4hrigen Follow-up.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Ergebnisse und Diskussion<\/jats:title>\n                <jats:p>Die tiefe Implantation war nur am NCC mit erh\u00f6hter Schrittmacherimplantationsrate assoziiert (<jats:italic>p<\/jats:italic>\u202f=\u20090,013), am LCC mit dem h\u00e4ufigeren Auftreten eines permanenten Linksschenkelblocks (<jats:italic>p<\/jats:italic>\u202f=\u20090,014). Neue oder vorbestehende Schrittmacherimplantationen hatten keinen Einfluss auf das 2\u2011j\u00e4hrige \u00dcberleben. Eine tiefe Implantation war nicht mit einer schlechteren \u00dcberlebensprognose assoziiert. Die Implantationstiefe k\u00f6nnte bez\u00fcglich der Bedeutung f\u00fcr neue Schrittmacherimplantationen standardisiert am NCC gemessen werden. In der Eingriffsplanung k\u00f6nnte eine Absch\u00e4tzung der Implantationstiefe am NCC oder LCC relevant f\u00fcr den Verlauf nach TAVI sein. Die Schrittmacherimplantation kann wie auch die tiefe Implantation am LCC oder NCC, bei Abwesenheit von mittel- bis hochgradigen paravalvul\u00e4ren Leckagen, als prognostisch sicher gewertet werden.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00399-021-00784-1","type":"journal-article","created":{"date-parts":[[2021,7,14]],"date-time":"2021-07-14T14:02:50Z","timestamp":1626271370000},"page":"371-379","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Einfluss einer tiefen Implantation auf Reizleitungsst\u00f6rungen nach Transkatheter-Aortenklappenimplantation"],"prefix":"10.1007","volume":"32","author":[{"given":"Mohammed","family":"Saad","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yannic","family":"Klaus","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"Buhse","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Puehler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georg","family":"Lutter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hatim","family":"Seoudy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Derk","family":"Frank","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,7,14]]},"reference":[{"key":"784_CR1","doi-asserted-by":"publisher","first-page":"2739","DOI":"10.1093\/eurheartj\/ehx391","volume":"38","author":"H Baumgartner","year":"2017","unstructured":"Baumgartner\u00a0H, Falk\u00a0V, Bax\u00a0JJ et\u00a0al (2017) 2017 ESC\/EACTS guidelines for the management of valvular heart disease. 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Von allen beteiligten Patienten liegt eine Einverst\u00e4ndniserkl\u00e4rung vor.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}}]}}