{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T00:26:11Z","timestamp":1791851171295,"version":"4.3.4"},"reference-count":33,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2008,7,19]],"date-time":"2008-07-19T00:00:00Z","timestamp":1216425600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Neuropathol"],"published-print":{"date-parts":[[2008,10]]},"DOI":"10.1007\/s00401-008-0415-x","type":"journal-article","created":{"date-parts":[[2008,7,18]],"date-time":"2008-07-18T07:02:23Z","timestamp":1216364543000},"page":"439-445","source":"Crossref","is-referenced-by-count":61,"title":["Immunohistochemical identification of messenger RNA-related proteins in basophilic inclusions of adult-onset atypical motor neuron disease"],"prefix":"10.1007","volume":"116","author":[{"given":"Kengo","family":"Fujita","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hidefumi","family":"Ito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoshi","family":"Nakano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshimi","family":"Kinoshita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reika","family":"Wate","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hirofumi","family":"Kusaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2008,7,19]]},"reference":[{"key":"415_CR1","doi-asserted-by":"crossref","first-page":"3227","DOI":"10.1242\/jcs.115.16.3227","volume":"115","author":"P Anderson","year":"2002","unstructured":"Anderson P, Kedersha N (2002) Stressful initiations. J Cell Sci 115:3227\u20133234","journal-title":"J Cell Sci"},{"key":"415_CR2","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1083\/jcb.200512082","volume":"172","author":"P Anderson","year":"2006","unstructured":"Anderson P, Kedersha N (2006) RNA granules. J Cell Biol 172:803\u2013808","journal-title":"J Cell Biol"},{"key":"415_CR3","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1261\/rna.2340405","volume":"11","author":"MA Andrei","year":"2005","unstructured":"Andrei MA, Ingelfinger D, Heintzmann R, Achsel T, Rivera-Pomar R, L\u00fchrmann R (2005) A role for eIF4E and eIF4E-transporter in targeting mRNPs to mammalian processing bodies. RNA 11:717\u2013727","journal-title":"RNA"},{"key":"415_CR4","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1016\/j.bbrc.2006.10.093","volume":"351","author":"T Arai","year":"2006","unstructured":"Arai T, Hasegawa M, Akiyama H, Ikeda K, Nonaka T, Mori H, Mann D, Tsuchiya K, Yoshida M, Hashizume Y, Oda T (2006) TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Biochem Biophys Res Commun 351:602\u2013611","journal-title":"Biochem Biophys Res Commun"},{"key":"415_CR5","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1038\/nrn2150","volume":"8","author":"CR Bramham","year":"2007","unstructured":"Bramham CR, Wells DG (2007) Dendric mRNA: transport, translation and function. Nat Rev Neurosci 8:776\u2013789","journal-title":"Nat Rev Neurosci"},{"key":"415_CR6","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1080\/146608200300079536","volume":"1","author":"BR Brooks","year":"2000","unstructured":"Brooks BR, Miller RG, Swash M, Munsat TL, World Federation of Neurology Research Group on Motor Neuron Diseases (2000) El Escorial revisited: Revised criteria for the diagnosis of amyotrophic lateral sclerosis. Amyotroph Lateral Scler Other Motor Neuron Disord 1:293\u2013299","journal-title":"Amyotroph Lateral Scler Other Motor Neuron Disord"},{"key":"415_CR7","doi-asserted-by":"crossref","first-page":"1774","DOI":"10.1093\/emboj\/20.7.1774","volume":"20","author":"E Buratti","year":"2001","unstructured":"Buratti E, D\u00f6rk T, Zuccato E, Pagani F, Romano M, Baralle FE (2001) Nuclear factor TDP-43 and SR proteins promote in vitro and in vivo CFTR exon 9 skipping. EMBO J 20:1774\u20131784","journal-title":"EMBO J"},{"key":"415_CR8","doi-asserted-by":"crossref","first-page":"36337","DOI":"10.1074\/jbc.M104236200","volume":"276","author":"E Buratti","year":"2001","unstructured":"Buratti E, Baralle FE (2001) Characterization and functional implications of the RNA binding properties of nuclear factor TDP-43, a novel splicing regulator of CFTR exon 9. J Biol Chem 276:36337\u201336343","journal-title":"J Biol Chem"},{"key":"415_CR9","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1007\/s00401-007-0237-2","volume":"114","author":"NJ Cairns","year":"2007","unstructured":"Cairns NJ, Bigio EH, Mackenzie IR, Neumann M, Lee VM, Hatanpaa KJ, White CL 3rd, Schneider JA, Grinberg LT, Halliday G, Duyckaerts C, Lowe JS, Holm IE, Tolnay M, Okamoto K, Yokoo H, Murayama S, Woulfe J, Munoz DG, Dickson DW, Ince PG, Trojanowski JQ, Mann DM, Consortium for frontotemporal lobar degeneration (2007) Neuropathologic diagnostic and nosologic criteria for frontotemporal lobar degeneration: consensus of the consortium for frontotemporal lobar degeneration. Acta Neuropathol (Berl) 114:5\u201322","journal-title":"Acta Neuropathol (Berl)"},{"key":"415_CR10","first-page":"1","volume":"14","author":"K Hamada","year":"1995","unstructured":"Hamada K, Fukazawa T, Yanagihara T, Yoshida K, Hamada T, Yoshimura N, Tashiro K (1995) Dementia with ALS features and diffuse Pick body-like inclusions (atypical Pick\u2019s disease?). Clin Neuropathol 14:1\u20136","journal-title":"Clin Neuropathol"},{"key":"415_CR11","first-page":"107","volume-title":"Amyotrophic lateral sclerosis","author":"A Hirano","year":"1979","unstructured":"Hirano A, Iwata M (1979) Pathology of motor neurons with special reference to amyotrophic lateral sclerosis and related disease. In: Tsubaki T, Toyokura Y (eds) Amyotrophic lateral sclerosis. University of Tokyo Press, Tokyo, pp 107\u2013133"},{"key":"415_CR12","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1111\/j.1440-1789.2006.00717.x","volume":"26","author":"K Ishihara","year":"2006","unstructured":"Ishihara K, Araki S, Ihori N, Shiota J, Kawamura M, Nakano I (2006) An autopsy case of frontotemporal dementia with severe dysarthria and motor neuron disease showing numerous basophilic inclusions. Neuropathology 26:447\u2013454","journal-title":"Neuropathology"},{"key":"415_CR13","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1134\/S0026893306060021","volume":"40","author":"PA Ivanov","year":"2006","unstructured":"Ivanov PA, Nadezhdina ES (2006) Stress granules: RNP-containing cytoplasmic bodies arising in stress: structure and mechanism of organization. Mol Biol 40:844\u2013850","journal-title":"Mol Biol"},{"key":"415_CR14","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.1083\/jcb.147.7.1431","volume":"147","author":"NL Kedersha","year":"1999","unstructured":"Kedersha NL, Gupta M, Li W, Miller I, Anderson P (1999) RNA-binding proteins TIA-1 and TIAR link the phosphorylation of eIF-2 alpha to the assembly of mammalian stress granules. J Cell Biol 147:1431\u20131442","journal-title":"J Cell Biol"},{"key":"415_CR15","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1083\/jcb.151.6.1257","volume":"151","author":"N Kedersha","year":"2000","unstructured":"Kedersha N, Cho MR, Li W, Yacono PW, Chen S, Gilks N, Golan DE, Anderson P (2000) Dynamic shuttling of TIA-1 accompanies the recruitment of mRNA to mammalian stress granules. J Cell Biol 151:1257\u20131268","journal-title":"J Cell Biol"},{"key":"415_CR16","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/j.neuron.2006.08.021","volume":"51","author":"MA Kiebler","year":"2006","unstructured":"Kiebler MA, Bassell GL (2006) Neuronal RNA granules: movers and makers. Neuron 51:685\u2013690","journal-title":"Neuron"},{"key":"415_CR17","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1016\/S0896-6273(01)00508-6","volume":"32","author":"AM Krichevsky","year":"2001","unstructured":"Krichevsky AM, Kosik KS (2001) Neuronal RNA granules: a link between RNA localization and stimulation-dependent translation. Neuron 32:683\u2013696","journal-title":"Neuron"},{"key":"415_CR18","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1007\/BF00307636","volume":"80","author":"H Kusaka","year":"1990","unstructured":"Kusaka H, Matsumoto S, Imai T (1990) An adult-onset case of sporadic motor neuron disease with basophilic inclusions. Acta Neuropathol (Berl) 80:660\u2013665","journal-title":"Acta Neuropathol (Berl)"},{"key":"415_CR19","first-page":"215","volume":"12","author":"H Kusaka","year":"1993","unstructured":"Kusaka H, Matsumoto S, Imai T (1993) Adult-onset motor neuron disease with basophilic intraneuronal inclusion bodies. Clin Neuropathol 12:215\u2013218","journal-title":"Clin Neuropathol"},{"key":"415_CR20","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1186\/gb-2003-4-7-223","volume":"4","author":"DA Mangus","year":"2003","unstructured":"Mangus DA, Evans MC, Jacobson A (2003) Poly(A)-binding proteins: multi-functional scaffolds for the post-transcriptional control of gene expression. Genome Biol 4:223\u2013236","journal-title":"Genome Biol"},{"key":"415_CR21","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1007\/s00401-006-0122-4","volume":"112","author":"Y Mizuno","year":"2006","unstructured":"Mizuno Y, Amari M, Takatama M, Aizawa H, Mihara B, Okamoto K (2006) Transferrin localizes in Bunina bodies in amyotrophic lateral sclerosis. Acta Neuropathol 112:597\u2013603","journal-title":"Acta Neuropathol"},{"key":"415_CR22","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1002\/ana.410160408","volume":"16","author":"D Munoz-Garcia","year":"1988","unstructured":"Munoz-Garcia D, Ludwin SK (1988) Classic and generalized variants of Pick\u2019s disease: a clinicopathological, ultrastructual, and immunocytochemical comparative study. Ann Neurol 16:467\u2013480","journal-title":"Ann Neurol"},{"key":"415_CR23","first-page":"211","volume-title":"Pick\u2019s disease and pick complex","author":"DG Munoz","year":"1998","unstructured":"Munoz DG (1998) The pathology of pick complex. In: Munoz DG (ed) Pick\u2019s disease and pick complex. Wiley, New York, pp 211\u2013241"},{"key":"415_CR24","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1002\/ana.410270208","volume":"27","author":"S Murayama","year":"1990","unstructured":"Murayama S, Mori H, Ihara Y, Bouldin TW, Suzuki K, Tomonaga M (1990) Immunocytochemical and ultrastructural studies of lower motor neurons in amyotrophic lateral sclerosis. Ann Neurol 27:137\u2013148","journal-title":"Ann Neurol"},{"key":"415_CR25","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1212\/01.wnl.0000171341.76482.15","volume":"65","author":"S Nakano","year":"2005","unstructured":"Nakano S, Shinde A, Ito H, Ito H, Kusaka H (2005) Messenger RNA degradation may be inhibited in sporadic inclusion body myositis. Neurology 65:420\u2013425","journal-title":"Neurology"},{"key":"415_CR26","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1001\/archneur.1972.00490160028004","volume":"27","author":"JS Nelson","year":"1972","unstructured":"Nelson JS, Prensky AL (1972) Sporadic juvenile amyotrophic lateral sclerosis. a clinic-pathological study of a case with neuronal cytoplasmic inclusions containing RNA. Arch Neurol 27:300\u2013306","journal-title":"Arch Neurol"},{"key":"415_CR27","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1126\/science.1134108","volume":"314","author":"M Neumann","year":"2006","unstructured":"Neumann M, Sampathu DM, Kwong LK, Truax AC, Micsenyi MC, Chou TT, Bruce J, Schuck T, Grossman M, Clark CM, McCluskey LF, Miller BL, Masliah E, Mackenzie IR, Feldman H, Feiden W, Kretzschmar HA, Trojanowski JQ, Lee VM (2006) Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Science 314:130\u2013133","journal-title":"Science"},{"key":"415_CR28","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1007\/BF00691069","volume":"44","author":"M Oda","year":"1978","unstructured":"Oda M, Akagawa N, Tabuchi Y, Tanabe H (1978) A sporadic juvenile case of the amyotrophic lateral sclerosis with neuronal intracytoplasmic inclusions. Acta Neuropathol (Berl) 44:211\u2013216","journal-title":"Acta Neuropathol (Berl)"},{"key":"415_CR29","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/0304-3940(91)90469-A","volume":"129","author":"K Okamoto","year":"1991","unstructured":"Okamoto K, Hirai S, Yamazaki T, Sun XY, Nakazato Y (1991) New ubiquitin-positive intraneuronal inclusions in the extra-motor cortices in patients with amyotrophic lateral sclerosis. Neurosci Lett 129:233\u2013236","journal-title":"Neurosci Lett"},{"key":"415_CR30","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1016\/j.molcel.2007.02.011","volume":"25","author":"R Parker","year":"2007","unstructured":"Parker R, Sheth U (2007) P bodies and the control of mRNA translation and degradation. Mol Cell 25:635\u2013646","journal-title":"Mol Cell"},{"key":"415_CR31","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1007\/s004010100371","volume":"102","author":"S Sasaki","year":"2001","unstructured":"Sasaki S, Toi S, Shirata A, Yamane K, Sakuma H, Iwata M (2001) Immunohistochemical and ultrastructual study of basophilic inclusions in adult-onset motor neuron disease. Acta Neuropathol (Berl) 102:200\u2013206","journal-title":"Acta Neuropathol (Berl)"},{"key":"415_CR32","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1111\/j.1471-4159.2007.05190.x","volume":"105","author":"IF Wang","year":"2008","unstructured":"Wang IF, Wu LS, Chang HY, Shen CK (2008) TDP-43, the signature protein of FTLD-U, is a neuronal activity-responsive factor. J Neurochem 105:797\u2013806","journal-title":"J Neurochem"},{"key":"415_CR33","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1007\/s00401-007-0329-z","volume":"115","author":"O Yokota","year":"2008","unstructured":"Yokota O, Tsuchiya K, Terada S, Ishizu H, Uchikado H, Ikeda M, Oyanagi K, Nakano I, Murayama S, Kuroda S, Akiyama H (2008) Basophilic inclusion body disease and neuronal intermediate filament inclusion disease: a comparative clinicopathological study. Acta Neuropathol 115:561\u2013575","journal-title":"Acta Neuropathol"}],"container-title":["Acta Neuropathologica"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00401-008-0415-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00401-008-0415-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00401-008-0415-x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,13]],"date-time":"2021-09-13T07:55:00Z","timestamp":1631519700000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00401-008-0415-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,7,19]]},"references-count":33,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2008,10]]}},"alternative-id":["415"],"URL":"https:\/\/doi.org\/10.1007\/s00401-008-0415-x","relation":{},"ISSN":["0001-6322","1432-0533"],"issn-type":[{"value":"0001-6322","type":"print"},{"value":"1432-0533","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,7,19]]}}}