{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T05:31:10Z","timestamp":1761975070833},"reference-count":74,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2009,2,5]],"date-time":"2009-02-05T00:00:00Z","timestamp":1233792000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Neuropathol"],"published-print":{"date-parts":[[2009,4]]},"DOI":"10.1007\/s00401-009-0493-4","type":"journal-article","created":{"date-parts":[[2009,2,4]],"date-time":"2009-02-04T07:14:29Z","timestamp":1233731669000},"page":"429-444","source":"Crossref","is-referenced-by-count":70,"title":["Clinicopathological characterization of Pick\u2019s disease versus frontotemporal lobar degeneration with ubiquitin\/TDP-43-positive inclusions"],"prefix":"10.1007","volume":"117","author":[{"given":"Osamu","family":"Yokota","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kuniaki","family":"Tsuchiya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tetsuaki","family":"Arai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saburo","family":"Yagishita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Osamu","family":"Matsubara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akihide","family":"Mochizuki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akira","family":"Tamaoka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mitsuru","family":"Kawamura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hidetoshi","family":"Yoshida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seishi","family":"Terada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideki","family":"Ishizu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shigetoshi","family":"Kuroda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haruhiko","family":"Akiyama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2009,2,5]]},"reference":[{"key":"493_CR1","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1016\/j.bbrc.2006.10.093","volume":"351","author":"T Arai","year":"2006","unstructured":"Arai T, Hasegawa M, Akiyama H, Ikeda K, Nonaka T, Mori H, Mann D, Tsuchiya K, Yoshida M, Hashizume Y, Oda T (2006) TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Biochem Biophys Res Commun 351:602\u2013611","journal-title":"Biochem Biophys Res Commun"},{"key":"493_CR2","first-page":"325","volume":"6","author":"K Arima","year":"1985","unstructured":"Arima K, Miyasaka Y (1985) An autopsy case of Pick\u2019s disease, with special reference to light and electron microscopical findings of Pick bodies and ballooned neurons. Neuropathology 6:325\u2013339 in Japanese with English abstract","journal-title":"Neuropathology"},{"key":"493_CR3","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1038\/nature05016","volume":"442","author":"M Baker","year":"2006","unstructured":"Baker M, Mackenzie IR, Pickering-Brown SM, Gass J, Rademakers R, Lindholm C, Snowden J, Adamson J, Sadovnick AD, Rollinson S, Cannon A, Dwosh E, Neary D, Melquist S, Richardson A, Dickson D, Berger Z, Eriksen J, Robinson T, Zehr C, Dickey CA, Crook R, McGowan E, Mann D, Boeve B, Feldman H, Hutton M (2006) Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17. Nature 442:916\u2013919","journal-title":"Nature"},{"key":"493_CR4","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1093\/brain\/awm320","volume":"131","author":"J Beck","year":"2008","unstructured":"Beck J, Rohrer JD, Campbell T, Isaacs A, Morrison KE, Goodall EF, Warrington EK, Stevens J, Revesz T, Holton J, Al-Sarraj S, King A, Scahill R, Warren JD, Fox NC, Rossor MN, Collinge J, Mead S (2008) A distinct clinical, neuropsychological and radiological phenotype is associated with progranulin gene mutations in a large UK series. Brain 131:706\u2013720","journal-title":"Brain"},{"key":"493_CR5","doi-asserted-by":"crossref","first-page":"3103","DOI":"10.1093\/brain\/awl268","volume":"129","author":"BF Boeve","year":"2006","unstructured":"Boeve BF, Baker M, Dickson DW, Parisi JE, Giannini C, Josephs KA, Hutton M, Pickering-Brown SM, Rademakers R, Tang-Wai D, Jack CR Jr, Kantarci K, Shiung MM, Golde T, Smith GE, Geda YE, Knopman DS, Petersen RC (2006) Frontotemporal dementia and parkinsonism associated with the IVS1+1G->A mutation in progranulin: a clinicopathologic study. Brain 129:3103\u20133114","journal-title":"Brain"},{"key":"493_CR6","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1007\/BF00308809","volume":"82","author":"H Braak","year":"1991","unstructured":"Braak H, Braak E (1991) Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol 82:239\u2013259","journal-title":"Acta Neuropathol"},{"key":"493_CR7","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1212\/01.WNL.0000052685.09194.39","volume":"60","author":"M Broe","year":"2003","unstructured":"Broe M, Hodges JR, Schofield E, Shepherd CE, Kril JJ, Halliday GM (2003) Staging disease severity in pathologically confirmed cases of frontotemporal dementia. Neurology 60:1005\u20131011","journal-title":"Neurology"},{"key":"493_CR8","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/S0304-3940(03)00100-9","volume":"341","author":"NJ Cairns","year":"2003","unstructured":"Cairns NJ, Perry RH, Jaros E, Burn D, McKeith IG, Lowe JS, Holton J, Rossor MN, Skullerud K, Duyckaerts C, Cruz-Sanchez FF, Lantos PL (2003) Patients with a novel neurofilamentopathy: dementia with neurofilament inclusions. Neurosci Lett 341:177\u2013180","journal-title":"Neurosci Lett"},{"key":"493_CR9","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1007\/s00401-007-0237-2","volume":"114","author":"NJ Cairns","year":"2007","unstructured":"Cairns NJ, Bigio EH, Mackenzie IR, Neumann M, Lee VM, Hatanpaa KJ, White CL 3rd, Schneider JA, Grinberg LT, Halliday G, Duyckaerts C, Lowe JS, Holm IE, Tolnay M, Okamoto K, Yokoo H, Murayama S, Woulfe J, Munoz DG, Dickson DW, Ince PG, Trojanowski JQ, Mann DM, Consortium for Frontotemporal Lobar Degeneration (2007) Neuropathologic diagnostic and nosologic criteria for frontotemporal lobar degeneration: consensus of the Consortium for Frontotemporal Lobar Degeneration. Acta Neuropathol 114:5\u201322","journal-title":"Acta Neuropathol"},{"key":"493_CR10","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1038\/nature05017","volume":"442","author":"M Cruts","year":"2006","unstructured":"Cruts M, Gijselinck I, van der Zee J, Engelborghs S, Wils H, Pirici D, Rademakers R, Vandenberghe R, Dermaut B, Martin JJ, van Duijn C, Peeters K, Sciot R, Santens P, De Pooter T, Mattheijssens M, Van den Broeck M, Cuijt I, Vennekens K, De Deyn PP, Kumar-Singh S, Van Broeckhoven C (2006) Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21. Nature 442:920\u2013924","journal-title":"Nature"},{"key":"493_CR11","doi-asserted-by":"crossref","first-page":"1984","DOI":"10.1093\/brain\/awh582","volume":"128","author":"RR Davies","year":"2005","unstructured":"Davies RR, Hodges JR, Kril JJ, Patterson K, Halliday GM, Xuereb JH (2005) The pathological basis of semantic dementia. Brain 128:1984\u20131995","journal-title":"Brain"},{"key":"493_CR12","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1212\/01.wnl.0000267701.58488.69","volume":"69","author":"S Davion","year":"2007","unstructured":"Davion S, Johnson N, Weintraub S, Mesulam MM, Engberg A, Mishra M, Baker M, Adamson J, Hutton M, Rademakers R, Bigio EH (2007) Clinicopathologic correlation in PGRN mutations. Neurology 69:1113\u20131121","journal-title":"Neurology"},{"key":"493_CR13","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1007\/s00401-007-0234-5","volume":"114","author":"DW Dickson","year":"2007","unstructured":"Dickson DW, Josephs KA, Amador-Ortiz C (2007) TDP-43 in differential diagnosis of motor neuron disorders. Acta Neuropathol 114:71\u201379","journal-title":"Acta Neuropathol"},{"key":"493_CR14","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1002\/ana.20873","volume":"59","author":"MS Forman","year":"2006","unstructured":"Forman MS, Farmer J, Johnson JK, Clark CM, Arnold SE, Coslett HB, Chatterjee A, Hurtig HI, Karlawish JH, Rosen HJ, Van Deerlin V, Lee VM, Miller BL, Trojanowski JQ, Grossman M (2006) Frontotemporal dementia: clinicopathological correlations. Ann Neurol 59:952\u2013962","journal-title":"Ann Neurol"},{"key":"493_CR15","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1212\/WNL.47.2.467","volume":"47","author":"T Fukui","year":"1996","unstructured":"Fukui T, Sugita K, Kawamura M, Shiota J, Nakano I (1996) Primary progressive apraxia in Pick\u2019s disease: a clinicopathologic study. Neurology 47:467\u2013473","journal-title":"Neurology"},{"key":"493_CR16","doi-asserted-by":"crossref","first-page":"2988","DOI":"10.1093\/hmg\/ddl241","volume":"15","author":"J Gass","year":"2006","unstructured":"Gass J, Cannon A, Mackenzie IR, Boeve B, Baker M, Adamson J, Crook R, Melquist S, Kuntz K, Petersen R, Josephs K, Pickering-Brown SM, Graff-Radford N, Uitti R, Dickson D, Wszolek Z, Gonzalez J, Beach TG, Bigio E, Johnson N, Weintraub S, Mesulam M, White CL 3rd, Woodruff B, Caselli R, Hsiung GY, Feldman H, Knopman D, Hutton M, Rademakers R (2006) Mutations in progranulin are a major cause of ubiquitin-positive frontotemporal lobar degeneration. Hum Mol Genet 15:2988\u20133001","journal-title":"Hum Mol Genet"},{"key":"493_CR17","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1002\/1531-8257(199907)14:4<674::AID-MDS1019>3.0.CO;2-X","volume":"14","author":"DA Grimes","year":"1999","unstructured":"Grimes DA, Bergeron CB, Lang AE (1999) Motor neuron disease-inclusion dementia presenting as cortical-basal ganglionic degeneration. Mov Disord 14:674\u2013680","journal-title":"Mov Disord"},{"key":"493_CR18","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1002\/mds.22078","volume":"23","author":"RJ Guerreiro","year":"2008","unstructured":"Guerreiro RJ, Santana I, Bras JM, Revesz T, Rebelo O, Ribeiro MH, Santiago B, Oliveira CR, Singleton A, Hardy J (2008) Novel progranulin mutation: screening for PGRN mutations in a Portuguese series of FTD\/CBS cases. Mov Disord 23:1269\u20131273","journal-title":"Mov Disord"},{"key":"493_CR19","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1002\/ana.21425","volume":"64","author":"M Hasegawa","year":"2008","unstructured":"Hasegawa M, Arai T, Nonaka T, Kametani F, Yoshida M, Hashizume Y, Beach TG, Buratti E, Baralle F, Morita M, Nakano I, Oda T, Tsuchiya K, Akiyama H (2008) Phosphorylated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Ann Neurol 64:60\u201370","journal-title":"Ann Neurol"},{"key":"493_CR20","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1111\/j.1572-0241.2007.01719.x","volume":"103","author":"F Higaki","year":"2008","unstructured":"Higaki F, Yokota O, Ohishi M (2008) Factors predictive of survival after percutaneous endoscopic gastrostomy in the elderly: is dementia really a risk factor? Am J Gastroenterol 103:1011\u20131016","journal-title":"Am J Gastroenterol"},{"key":"493_CR21","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1002\/ana.20203","volume":"56","author":"JR Hodges","year":"2004","unstructured":"Hodges JR, Davies RR, Xuereb JH, Casey B, Broe M, Bak TH, Kril JJ, Halliday GM (2004) Clinicopathological correlates in frontotemporal dementia. Ann Neurol 56:399\u2013406","journal-title":"Ann Neurol"},{"key":"493_CR22","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1046\/j.1440-1789.2000.00270.x","volume":"20","author":"K Ikeda","year":"2000","unstructured":"Ikeda K (2000) Neuropathological discrepancy between Japanese Pick\u2019s disease without Pick bodies and frontal lobe degeneration type of frontotemporal dementia proposed by Lund and Manchester Group. Neuropathology 20:76\u201382","journal-title":"Neuropathology"},{"key":"493_CR23","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1007\/s00401-001-0513-5","volume":"104","author":"K Ikeda","year":"2002","unstructured":"Ikeda K, Akiyama H, Arai T, Ueno H, Tsuchiya K, Kosaka K (2002) Morphometrical reappraisal of motor neuron system of Pick\u2019s disease and amyotrophic lateral sclerosis with dementia. Acta Neuropathol 104:21\u201328","journal-title":"Acta Neuropathol"},{"key":"493_CR24","first-page":"1167","volume":"36","author":"M Ikeda","year":"1994","unstructured":"Ikeda M, Ikeda K, Endo M, Haga C, Mizutani Y (1994) An autopsied case of slowly progressive Pick\u2019s disease. Seishin Igaku (Clinical Psychiatry) 36:1167\u20131171 in Japanese with English abstract","journal-title":"Seishin Igaku (Clinical Psychiatry)"},{"key":"493_CR25","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1159\/000077151","volume":"17","author":"M Ikeda","year":"2004","unstructured":"Ikeda M, Ishikawa T, Tanabe H (2004) Epidemiology of frontotemporal lobar degeneration. Dementia Geriatr Cogn Disord 17:265\u2013268","journal-title":"Dementia Geriatr Cogn Disord"},{"key":"493_CR26","first-page":"82","volume":"18","author":"H Ishino","year":"1972","unstructured":"Ishino H, Ikeda H (1972) Four autopsy cases of Pick\u2019s disease\u2014clinicopathological findings (in Japanese with English abstract). Kyushu Neuro psychiatry 18:82\u201386","journal-title":"Kyushu Neuro psychiatry"},{"key":"493_CR27","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1006\/neur.1996.0046","volume":"5","author":"M Jackson","year":"1996","unstructured":"Jackson M, Lennox G, Lowe J (1996) Motor neuron disease-inclusion dementia. Neurodegeneration 5:339\u2013350","journal-title":"Neurodegeneration"},{"key":"493_CR28","doi-asserted-by":"crossref","first-page":"2291","DOI":"10.1093\/brain\/awg231","volume":"126","author":"KA Josephs","year":"2003","unstructured":"Josephs KA, Holton JL, Rossor MN, Braendgaard H, Ozawa T, Fox NC, Petersen RC, Pearl GS, Ganguly M, Rosa P, Laursen H, Parisi JE, Waldemar G, Quinn NP, Dickson DW, Revesz T (2003) Neurofilament inclusion body disease: a new proteinopathy? Brain 126:2291\u20132303","journal-title":"Brain"},{"key":"493_CR29","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1111\/j.1365-2990.2003.00545.x","volume":"30","author":"KA Josephs","year":"2004","unstructured":"Josephs KA, Holton JL, Rossor MN, Godbolt AK, Ozawa T, Strand K, Khan N, Al-Sarraj S, Revesz T (2004) Frontotemporal lobar degeneration and ubiquitin immunohistochemistry. Neuropathol Appl Neurobiol 30:369\u2013373","journal-title":"Neuropathol Appl Neurobiol"},{"key":"493_CR30","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1097\/nen.0b013e31803020cf","volume":"66","author":"KA Josephs","year":"2007","unstructured":"Josephs KA, Ahmed Z, Katsuse O, Parisi JF, Boeve BF, Knopman DS, Petersen RC, Davies P, Duara R, Graff-Radford NR, Uitti RJ, Rademakers R, Adamson J, Baker M, Hutton ML, Dickson DW (2007) Neuropathologic features of frontotemporal lobar degeneration with ubiquitin-positive inclusions with progranulin gene (PGRN) mutations. J Neuropathol Exp Neurol 66:142\u2013151","journal-title":"J Neuropathol Exp Neurol"},{"key":"493_CR31","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1007\/s00401-008-0397-8","volume":"116","author":"KA Josephs","year":"2008","unstructured":"Josephs KA, Lin WL, Ahmed Z, Stroh DA, Graff-Radford NR, Dickson DW (2008) Frontotemporal lobar degeneration with ubiquitin-positive, but TDP-43-negative inclusions. Acta Neuropathol 116:159\u2013167","journal-title":"Acta Neuropathol"},{"key":"493_CR32","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1046\/j.1440-1789.1999.00235.x","volume":"19","author":"M Kawamura","year":"1999","unstructured":"Kawamura M, Mochizuki S (1999) Primary progressive apraxia. Neuropathology 19:249\u2013258","journal-title":"Neuropathology"},{"key":"493_CR33","doi-asserted-by":"crossref","first-page":"1996","DOI":"10.1093\/brain\/awh598","volume":"128","author":"A Kertesz","year":"2005","unstructured":"Kertesz A, McMonagle P, Blair M, Davidson W, Munoz DG (2005) The evolution and pathology of frontotemporal dementia. Brain 128:1996\u20132005","journal-title":"Brain"},{"key":"493_CR34","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1002\/ana.20700","volume":"59","author":"JA Knibb","year":"2006","unstructured":"Knibb JA, Xuereb JH, Patterson K, Hodges JR (2006) Clinical and pathological characterization of progressive aphasia. Ann Neurol 59:156\u2013165","journal-title":"Ann Neurol"},{"key":"493_CR35","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1212\/WNL.40.2.251","volume":"40","author":"DS Knopman","year":"1990","unstructured":"Knopman DS, Mastri AR, Frey WH 2nd, Sung JH, Rustan T (1990) Dementia lacking distinctive histologic features: a common non-Alzheimer degenerative dementia. Neurology 40:251\u2013256","journal-title":"Neurology"},{"key":"493_CR36","first-page":"1181","volume":"18","author":"K Kosaka","year":"1976","unstructured":"Kosaka K (1976) On aphasia of Pick\u2019s disease\u2014a review of our own 3 cases and 49 autopsy cases in Japan (in Japanese). Seishin Igaku (Clinical Psychiatry) 18:1181\u20131189","journal-title":"Seishin Igaku (Clinical Psychiatry)"},{"key":"493_CR37","first-page":"33","volume":"82","author":"K Kosaka","year":"1980","unstructured":"Kosaka K, Matsushita M, Oyanagi S, Hato K, Mehraein P (1980) Pick\u2019s disease with concomitant traumatic brain damages\u2013Five autopsied cases and a critical review of literatures (in Japanese with English abstract). Seishin Shinkeigaku Zasshi (Psychiatria et Neurologia Japonica) 82:33\u201347","journal-title":"Seishin Shinkeigaku Zasshi (Psychiatria et Neurologia Japonica)"},{"key":"493_CR38","first-page":"1171","volume":"27","author":"K Kosaka","year":"1985","unstructured":"Kosaka K, Ikeda K, Kobayashi K, Hamamoto J, Matsushita M (1985) On pyramidal tract lesions in Pick\u2019s disease (in Japanese). Clinical Psychiatry 27:1171\u20131178","journal-title":"Clinical Psychiatry"},{"key":"493_CR39","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1093\/brain\/awn012","volume":"131","author":"I Le Ber","year":"2008","unstructured":"Le Ber I, Camuzat A, Hannequin D, Pasquier F, Guedj E, Rovelet-Lecrux A, Hahn-Barma V, van der Zee J, Clot F, Bakchine S, Puel M, Ghanim M, Lacomblez L, Mikol J, Deramecourt V, Lejeune P, de la Sayette V, Belliard S, Vercelletto M, Meyrignac C, Van Broeckhoven C, Lambert JC, Verpillat P, Campion D, Habert MO, Dubois B, Brice A, French research network on FTD\/FTD-MND (2008) Phenotype variability in progranulin mutation carriers: a clinical, neuropsychological, imaging and genetic study. Brain 131:732\u2013746","journal-title":"Brain"},{"key":"493_CR40","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1007\/s00401-007-0223-8","volume":"114","author":"IR Mackenzie","year":"2007","unstructured":"Mackenzie IR (2007) The neuropathology and clinical phenotype of FTD with progranulin mutations. Acta Neuropathol 114:49\u201354","journal-title":"Acta Neuropathol"},{"key":"493_CR41","doi-asserted-by":"crossref","first-page":"1282","DOI":"10.1093\/brain\/awn061","volume":"131","author":"IR Mackenzie","year":"2008","unstructured":"Mackenzie IR, Foti D, Woulfe J, Hurwitz TA (2008) Atypical frontotemporal lobar degeneration with ubiquitin-positive, TDP-43-negative neuronal inclusions. Brain 131:1282\u20131293","journal-title":"Brain"},{"key":"493_CR42","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1007\/s00401-008-0460-5","volume":"117","author":"IR Mackenzie","year":"2009","unstructured":"Mackenzie IR, Neumann M, Bigio EH, Cairns NJ, Alafuzoff I, Kril J, Kovacs GG, Ghetti B, Halliday G, Holm IE, Ince PG, Kamphorst W, Revesz T, Rozemuller AJ, Kumar-Singh S, Akiyama H, Baborie A, Spina S, Dickson DW, Trojanowski JQ, Mann DM (2009) Nomenclature for neuropathologic subtypes of frontotemporal lobar degeneration: consensus recommendations. Acta Neuropathol 117:15\u201318","journal-title":"Acta Neuropathol"},{"key":"493_CR43","first-page":"397","volume":"26","author":"K Masaki","year":"1996","unstructured":"Masaki K, Maeda M, Furuhashi N, Kowa H (1996) Slowly-progressive aphasia and its symptoms\u2014considered in reference to its related literature (in Japanese with English abstract). Kitasato Med 26:397\u2013411","journal-title":"Kitasato Med"},{"key":"493_CR44","doi-asserted-by":"crossref","first-page":"3115","DOI":"10.1093\/brain\/awl276","volume":"129","author":"M Masellis","year":"2006","unstructured":"Masellis M, Momeni P, Meschino W, Heffner R Jr, Elder J, Sato C, Liang Y, St George-Hyslop P, Hardy J, Bilbao J, Black S, Rogaeva E (2006) Novel splicing mutation in the progranulin gene causing familial corticobasal syndrome. Brain 129:3115\u20133123","journal-title":"Brain"},{"key":"493_CR45","first-page":"106","volume":"15","author":"T Mii","year":"1969","unstructured":"Mii T, Sudo K, Hayashi Y (1969) Ein Fall der Pickschen Krankheit (in Japanese with German abstract). Kyushu Neuro-psychiatry 15:106\u2013113","journal-title":"Kyushu Neuro-psychiatry"},{"key":"493_CR46","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1002\/ana.410160408","volume":"16","author":"D Munoz-Garcia","year":"1984","unstructured":"Munoz-Garcia D, Ludwin SK (1984) Classic and generalized variants of Pick\u2019s disease: a clinicopathological, ultrastructural, and immunocytochemical comparative study. Ann Neurol 16:467\u2013480","journal-title":"Ann Neurol"},{"issue":"Suppl 5","key":"493_CR47","doi-asserted-by":"crossref","first-page":"S24","DOI":"10.1002\/ana.10571","volume":"54","author":"DG Munoz","year":"2003","unstructured":"Munoz DG, Dickson DW, Bergeron C, Mackenzie IR, Delacourte A, Zhukareva V (2003) The neuropathology and biochemistry of frontotemporal dementia. Ann Neurol 54(Suppl 5):S24\u2013S28","journal-title":"Ann Neurol"},{"key":"493_CR48","doi-asserted-by":"crossref","first-page":"1546","DOI":"10.1212\/WNL.51.6.1546","volume":"51","author":"D Neary","year":"1998","unstructured":"Neary D, Snowden JS, Gustafson L, Passant U, Stuss D, Black S, Freedman M, Kertesz A, Robert PH, Albert M, Boone K, Miller BL, Cummings J, Benson DF (1998) Frontotemporal lobar degeneration: a consensus on clinical diagnostic criteria. Neurology 51:1546\u20131554","journal-title":"Neurology"},{"key":"493_CR49","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1126\/science.1134108","volume":"314","author":"M Neumann","year":"2006","unstructured":"Neumann M, Sampathu DM, Kwong LK, Truax AC, Micsenyi MC, Chou TT, Bruce J, Schuck T, Grossman M, Clark CM, McCluskey LF, Miller BL, Masliah E, Mackenzie IR, Feldman H, Feiden W, Kretzschmar HA, Trojanowski JQ, Lee VM (2006) Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Science 314:130\u2013133","journal-title":"Science"},{"key":"493_CR50","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/j.expneurol.2007.11.019","volume":"210","author":"K Obi","year":"2008","unstructured":"Obi K, Akiyama H, Kondo H, Shimomura Y, Hasegawa M, Iwatsubo T, Mizuno Y, Mochizuki H (2008) Relationship of phosphorylated alpha-synuclein and tau accumulation to Abeta deposition in the cerebral cortex of dementia with Lewy bodies. Exp Neurol 210:409\u2013420","journal-title":"Exp Neurol"},{"key":"493_CR51","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1111\/j.1440-1789.2006.00744.x","volume":"27","author":"T Oda","year":"2007","unstructured":"Oda T, Tsuchiya K, Arai T, Togo T, Uchikado H, de Silva R, Lees A, Akiyama H, Haga C, Ikeda K, Kato M, Kato Y, Hara T, Onaya M, Hori K, Teramoto H, Tominaga I (2007) Pick\u2019s disease with Pick bodies: an unusual autopsy case showing degeneration of the pontine nucleus, dentate nucleus, Clarke\u2019s column, and lower motor neuron. Neuropathology 27:81\u201389","journal-title":"Neuropathology"},{"key":"493_CR52","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1007\/BF02878348","volume":"101","author":"K Onari","year":"1926","unstructured":"Onari K, Spatz H (1926) Anatomische Beitr\u00e4ge zur Lehre von Pickschen umschriebenen Gr\u00f6\u00dfhirnrinden Atrophie (Picksche Krankheit). Z Ges Neurol Psychiatr 101:470\u2013511","journal-title":"Z Ges Neurol Psychiatr"},{"key":"493_CR53","first-page":"233","volume":"57","author":"S Ota","year":"2005","unstructured":"Ota S, Tsuchiya K, Anno M, Akiyama H (2005) An autopsy case of dementia lacking distinctive histologic features showing semantic dementia. No To Shinkei 57:233\u2013238","journal-title":"No To Shinkei"},{"key":"493_CR54","first-page":"441","volume":"23","author":"S Oyanagi","year":"1979","unstructured":"Oyanagi S, Tanaka M, Omori T, Matsuchita M, Ishii T (1979) Regular arrangements of tubular structures in Pick bodies formed in an autopsied case of Pick\u2019s disease (in Japanese with English abstract). Shinkei Kenky\u016b no Shimpo (Adv in Neurol Sci) 23:441\u2013451","journal-title":"Shinkei Kenky\u016b no Shimpo (Adv in Neurol Sci)"},{"key":"493_CR55","doi-asserted-by":"crossref","first-page":"2441","DOI":"10.1093\/brain\/awh265","volume":"127","author":"DC Paviour","year":"2004","unstructured":"Paviour DC, Lees AJ, Josephs KA, Ozawa T, Ganguly M, Strand C, Godbolt A, Howard RS, Revesz T, Holton JL (2004) Frontotemporal lobar degeneration with ubiquitin-only-immunoreactive neuronal changes: broadening the clinical picture to include progressive supranuclear palsy. Brain 127:2441\u20132451","journal-title":"Brain"},{"key":"493_CR56","first-page":"165","volume":"17","author":"A Pick","year":"1892","unstructured":"Pick A (1892) Ueber die Beziehungen der senilen Hirnatrophie zur Aphasie. Prager Med Wochenschr 17:165\u2013167","journal-title":"Prager Med Wochenschr"},{"key":"493_CR57","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1007\/s00401-007-0241-6","volume":"114","author":"SM Pickering-Brown","year":"2007","unstructured":"Pickering-Brown SM (2007) Progranulin and frontotemporal lobar degeneration. Acta Neruopathol 114:39\u201347","journal-title":"Acta Neruopathol"},{"key":"493_CR58","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1093\/brain\/awm331","volume":"131","author":"SM Pickering-Brown","year":"2008","unstructured":"Pickering-Brown SM, Rollinson S, Du Plessis D, Morrison KE, Varma A, Richardson AM, Neary D, Snowden JS, Mann DM (2008) Frequency and clinical characteristics of progranulin mutation carriers in the Manchester frontotemporal lobar degeneration cohort: comparison with patients with MAPT and no known mutations. Brain 131:721\u2013731","journal-title":"Brain"},{"key":"493_CR59","doi-asserted-by":"crossref","first-page":"1615","DOI":"10.1212\/WNL.58.11.1615","volume":"58","author":"E Ratnavalli","year":"2002","unstructured":"Ratnavalli E, Brayne C, Dawson K, Hodges JR (2002) The prevalence of frontotemporal dementia. Neurology 58:1615\u20131621","journal-title":"Neurology"},{"key":"493_CR60","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1212\/01.wnl.0000259035.98480.ed","volume":"68","author":"GD Rabinovici","year":"2007","unstructured":"Rabinovici GD, Furst AJ, O\u2019Neil JP, Racine CA, Mormino EC, Baker SL, Chetty S, Patel P, Pagliaro TA, Klunk WE, Mathis CA, Rosen HJ, Miller BL, Jagust WJ (2007) 11C-PIB PET imaging in Alzheimer disease and frontotemporal lobar degeneration. Neurology 68:1205\u20131212","journal-title":"Neurology"},{"key":"493_CR61","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1007\/s00401-008-0395-x","volume":"116","author":"S Roeber","year":"2008","unstructured":"Roeber S, Mackenzie IR, Kretzschmar HA, Neumann M (2008) TDP-43-negative FTLD-U is a significant new clinico-pathological subtype of FTLD. Acta Neuropathol 116:147\u2013157","journal-title":"Acta Neuropathol"},{"key":"493_CR62","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1093\/brain\/123.2.267","volume":"123","author":"MN Rossor","year":"2000","unstructured":"Rossor MN, Revesz T, Lantos PL, Warrington EK (2000) Semantic dementia with ubiquitin-positive tau-negative inclusion bodies. Brain 123:267\u2013276","journal-title":"Brain"},{"key":"493_CR63","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1007\/s00401-005-1079-4","volume":"110","author":"J Shi","year":"2005","unstructured":"Shi J, Shaw CL, Du Plessis D, Richardson AM, Bailey KL, Julien C, Stopford C, Thompson J, Varma A, Craufurd D, Tian J, Pickering-Brown S, Neary D, Snowden JS, Mann DM (2005) Histopathological changes underlying frontotemporal lobar degeneration with clinicopathological correlation. Acta Neuropathol 110:501\u2013512","journal-title":"Acta Neuropathol"},{"key":"493_CR64","doi-asserted-by":"crossref","first-page":"3091","DOI":"10.1093\/brain\/awl267","volume":"129","author":"JS Snowden","year":"2006","unstructured":"Snowden JS, Pickering-Brown SM, Mackenzie IR, Richardson AM, Varma A, Neary D, Mann DM (2006) Progranulin gene mutations associated with frontotemporal dementia and progressive non-fluent aphasia. Brain 129:3091\u20133102","journal-title":"Brain"},{"key":"493_CR65","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1007\/s00401-007-0236-3","volume":"114","author":"J Snowden","year":"2007","unstructured":"Snowden J, Neary D, Mann D (2007) Frontotemporal lobar degeneration: clinical and pathological relationships. Acta Neuropathol 114:31\u201338","journal-title":"Acta Neuropathol"},{"key":"493_CR66","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1097\/nen.0b013e3181567873","volume":"66","author":"S Spina","year":"2007","unstructured":"Spina S, Murrell JR, Huey ED, Wassermann EM, Pietrini P, Grafman J, Ghetti B (2007) Corticobasal syndrome associated with the A9D progranulin mutation. J Neuropathol Exp Neurol 66:892\u2013900","journal-title":"J Neuropathol Exp Neurol"},{"key":"493_CR67","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1007\/s004010100406","volume":"102","author":"K Tsuchiya","year":"2001","unstructured":"Tsuchiya K, Ishizu H, Nakano I, Kita Y, Sawabe M, Haga C, Kuyama K, Nishinaka T, Oyanagi K, Ikeda K, Kuroda S (2001) Distribution of basal ganglia lesions in generalized variant of Pick\u2019s disease: a clinicopathological study of four autopsy cases. Acta Neuropathol 102:441\u2013448","journal-title":"Acta Neuropathol"},{"key":"493_CR68","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1007\/s004010100406","volume":"102","author":"K Tsuchiya","year":"2001","unstructured":"Tsuchiya K, Ikeda M, Hasegawa K, Fukui T, Kuroiwa T, Haga C, Oyanagi S, Nakano I, Matsushita M, Yagishita S, Ikeda K (2001) Distribution of cerebral cortical lesions in Pick\u2019s disease with Pick bodies: a clinicopathological study of six autopsy cases showing unusual clinical presentations. Acta Neuropathol 102:553\u2013571","journal-title":"Acta Neuropathol"},{"key":"493_CR69","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1007\/s00401-005-0028-6","volume":"112","author":"K Tsuchiya","year":"2006","unstructured":"Tsuchiya K, Piao YS, Oda T, Mochizuki A, Arima K, Hasegawa K, Haga C, Kakita A, Hori K, Tominaga I, Yagishita S, Akiyama H, Takahashi H (2006) Pathological heterogeneity of the precentral gyrus in Pick\u2019s disease: a study of 16 autopsy cases. Acta Neuropathol 112:29\u201342","journal-title":"Acta Neuropathol"},{"key":"493_CR70","doi-asserted-by":"crossref","unstructured":"Uchihara T, Tsuchiya K (2008) Neuropathology of Pick body disease. In: Duyckaerts C, Litvan I (eds) Handbook of clinical neurology, vol 89 (Third series), Dementias. Elsevier, Amsterdam, pp 415\u2013430","DOI":"10.1016\/S0072-9752(07)01238-9"},{"key":"493_CR71","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1111\/j.1468-1331.2005.01072.x","volume":"12","author":"O Yokota","year":"2005","unstructured":"Yokota O, Sasaki K, Fujisawa Y, Takahashi J, Terada S, Ishihara T, Nakashima H, Kugo A, Ata T, Ishizu H, Kuroda S (2005) Frequency of early and late-onset dementias in a Japanese memory disorders clinic. Eur J Neurol 12:782\u2013790","journal-title":"Eur J Neurol"},{"key":"493_CR72","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1007\/s00401-006-0141-1","volume":"112","author":"O Yokota","year":"2006","unstructured":"Yokota O, Tsuchiya K, Oda T, Ishihara T, de Silva R, Lees AJ, Arai T, Uchihara T, Ishizu H, Kuroda S, Akiyama H (2006) Amyotrophic lateral sclerosis with dementia: an autopsy case showing many Bunina bodies, tau-positive neuronal and astrocytic plaque-like pathologies, and pallido-nigral degeneration. Acta Neuropathol 112:633\u2013645","journal-title":"Acta Neuropathol"},{"key":"493_CR73","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1007\/s00401-006-0149-6","volume":"112","author":"O Yokota","year":"2006","unstructured":"Yokota O, Tsuchiya K, Itoh Y, Ishizu H, Akiyama H, Ikeda M, Kuzuhara S, Otomo E (2006) Frontotemporal lobar degeneration with ubiquitin pathology: an autopsy case presenting with semantic dementia and upper motor neuron signs with a clinical course of 19\u00a0years. Acta Neuropathol 112:739\u2013749","journal-title":"Acta Neuropathol"},{"key":"493_CR74","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1007\/s00401-007-0329-z","volume":"115","author":"O Yokota","year":"2008","unstructured":"Yokota O, Tsuchiya K, Terada S, Ishizu H, Uchikado H, Ikeda M, Oyanagi K, Nakano I, Murayama S, Kuroda S, Akiyama H (2008) Basophilic inclusion body disease and neuronal intermediate filament inclusion disease: a comparative clinicopathological study. Acta Neuropathol 115:561\u2013575","journal-title":"Acta Neuropathol"}],"container-title":["Acta Neuropathologica"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00401-009-0493-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00401-009-0493-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00401-009-0493-4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,28]],"date-time":"2019-05-28T17:23:21Z","timestamp":1559064201000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00401-009-0493-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,2,5]]},"references-count":74,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2009,4]]}},"alternative-id":["493"],"URL":"https:\/\/doi.org\/10.1007\/s00401-009-0493-4","relation":{},"ISSN":["0001-6322","1432-0533"],"issn-type":[{"value":"0001-6322","type":"print"},{"value":"1432-0533","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,2,5]]}}}