{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T06:32:36Z","timestamp":1791268356879,"version":"4.1.0"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2013,8,31]],"date-time":"2013-08-31T00:00:00Z","timestamp":1377907200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Neuropathol"],"published-print":{"date-parts":[[2013,10]]},"DOI":"10.1007\/s00401-013-1171-0","type":"journal-article","created":{"date-parts":[[2013,8,30]],"date-time":"2013-08-30T13:06:57Z","timestamp":1377868017000},"page":"537-544","source":"Crossref","is-referenced-by-count":187,"title":["Globular glial tauopathies (GGT): consensus recommendations"],"prefix":"10.1007","volume":"126","author":[{"given":"Zeshan","family":"Ahmed","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eileen H.","family":"Bigio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Herbert","family":"Budka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dennis W.","family":"Dickson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isidro","family":"Ferrer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernardino","family":"Ghetti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giorgio","family":"Giaccone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kimmo J.","family":"Hatanpaa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janice L.","family":"Holton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keith A.","family":"Josephs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Powers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salvatore","family":"Spina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hitoshi","family":"Takahashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"III","given":"Charles L.","family":"White","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tamas","family":"Revesz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabor G.","family":"Kovacs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2013,8,31]]},"reference":[{"key":"1171_CR1","doi-asserted-by":"publisher","first-page":"415","DOI":"10.1007\/s00401-011-0857-4","volume":"122","author":"Z Ahmed","year":"2011","unstructured":"Ahmed Z, Doherty KM, Silveira-Moriyama L et al (2011) Globular glial tauopathies (GGT) presenting with motor neuron disease or frontotemporal dementia: an emerging group of 4-repeat tauopathies. Acta Neuropathol 122:415\u2013428","journal-title":"Acta Neuropathol"},{"key":"1171_CR2","doi-asserted-by":"publisher","first-page":"469","DOI":"10.1016\/S0197-0186(01)00054-7","volume":"39","author":"RW Berry","year":"2001","unstructured":"Berry RW, Quinn B, Johnson N, Cochran EJ, Ghoshal N, Binder LI (2001) Pathological glial tau accumulations in neurodegenerative disease: review and case report. Neurochem Int 39:469\u2013479","journal-title":"Neurochem Int"},{"key":"1171_CR3","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1093\/jnen\/60.4.328","volume":"60","author":"EH Bigio","year":"2001","unstructured":"Bigio EH, Lipton AM, Yen SH et al (2001) Frontal lobe dementia with novel tauopathy: sporadic multiple system tauopathy with dementia. J Neuropathol Exp Neurol 60:328\u2013341","journal-title":"J Neuropathol Exp Neurol"},{"key":"1171_CR4","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1016\/S0304-3940(97)00474-6","volume":"230","author":"NJ Cairns","year":"1997","unstructured":"Cairns NJ, Atkinson PF, Hanger DP, Anderton BH, Daniel SE, Lantos PL (1997) Tau protein in the glial cytoplasmic inclusions of multiple system atrophy can be distinguished from abnormal tau in Alzheimer\u2019s disease. Neurosci Lett 230:49\u201352","journal-title":"Neurosci Lett"},{"key":"1171_CR5","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1002\/9781444341256.ch15","volume-title":"Neurodegeneration: The molecular pathology of dementia and movement disorders","author":"DW Dickson","year":"2011","unstructured":"Dickson DW, Hauw JJ, Agid Y, Litvan I (2011) Progressive supranuclear palsy and corticobasal degeneration. In: Dickson DW, Weller RO (eds) Neurodegeneration: The molecular pathology of dementia and movement disorders, 2nd edn. Wiley-Blackwell, Chichester, West Sussex, pp 135\u2013155","edition":"2"},{"key":"1171_CR6","doi-asserted-by":"publisher","first-page":"419","DOI":"10.1007\/s00401-003-0756-4","volume":"106","author":"I Ferrer","year":"2003","unstructured":"Ferrer I, Hernandez I, Boada M et al (2003) Primary progressive aphasia as the initial manifestation of corticobasal degeneration and unusual tauopathies. Acta Neuropathol 106:419\u2013435","journal-title":"Acta Neuropathol"},{"key":"1171_CR7","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1007\/s00401-010-0649-2","volume":"120","author":"YJ Fu","year":"2010","unstructured":"Fu YJ, Nishihira Y, Kuroda S et al (2010) Sporadic four-repeat tauopathy with frontotemporal lobar degeneration, Parkinsonism, and motor neuron disease: a distinct clinicopathological and biochemical disease entity. Acta Neuropathol 120:21\u201332","journal-title":"Acta Neuropathol"},{"key":"1171_CR8","first-page":"1","volume":"19","author":"F Gallyas","year":"1971","unstructured":"Gallyas F (1971) Silver staining of Alzheimer\u2019s neurofibrillary changes by means of physical development. Acta morphol Acad Sci Hung 19:1\u20138","journal-title":"Acta morphol Acad Sci Hung"},{"key":"1171_CR9","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1002\/9781444341256.ch14","volume-title":"Neurodegeneration: the molecular pathology of dementia and movement disorders","author":"B Ghetti","year":"2011","unstructured":"Ghetti B, Wszolek EK, Boeve BF, Spina S, Goedert M (2011) Frontotemporal dementia and Parkinsonism linked to chromosome 17. In: Dickson DW, Weller RO (eds) Neurodegeneration: the molecular pathology of dementia and movement disorders. Wiley-Blackwell, Chichester, West Sussex, pp 110\u2013134"},{"key":"1171_CR10","doi-asserted-by":"publisher","first-page":"468","DOI":"10.1111\/j.1365-2990.2007.00927.x","volume":"34","author":"G Giaccone","year":"2008","unstructured":"Giaccone G, Marcon G, Mangieri M et al (2008) Atypical tauopathy with massive involvement of the white matter. Neuropathol Appl Neurobiol 34:468\u2013472","journal-title":"Neuropathol Appl Neurobiol"},{"key":"1171_CR11","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1002\/ana.10163","volume":"51","author":"S Hayashi","year":"2002","unstructured":"Hayashi S, Toyoshima Y, Hasegawa M et al (2002) Late-onset frontotemporal dementia with a novel exon 1 (Arg5His) tau gene mutation. Ann Neurol 51:525\u2013530","journal-title":"Ann Neurol"},{"key":"1171_CR12","doi-asserted-by":"publisher","first-page":"396","DOI":"10.1097\/01.jnen.0000218446.38158.61","volume":"65","author":"KA Josephs","year":"2006","unstructured":"Josephs KA, Katsuse O, Beccano-Kelly DA et al (2006) Atypical progressive supranuclear palsy with corticospinal tract degeneration. J Neuropathol Exp Neurol 65:396\u2013405","journal-title":"J Neuropathol Exp Neurol"},{"key":"1171_CR13","doi-asserted-by":"publisher","first-page":"963","DOI":"10.1097\/NEN.0b013e318187a80f","volume":"67","author":"GG Kovacs","year":"2008","unstructured":"Kovacs GG, Majtenyi K, Spina S et al (2008) White matter tauopathy with globular glial inclusions: a distinct sporadic frontotemporal lobar degeneration. J Neuropathol Exp Neurol 67:963\u2013975","journal-title":"J Neuropathol Exp Neurol"},{"key":"1171_CR14","doi-asserted-by":"publisher","first-page":"2548","DOI":"10.1093\/brain\/awr160","volume":"134","author":"T Lashley","year":"2011","unstructured":"Lashley T, Rohrer JD, Bandopadhyay R et al (2011) A comparative clinical, pathological, biochemical and genetic study of fused in sarcoma proteinopathies. Brain 134:2548\u20132564","journal-title":"Brain"},{"key":"1171_CR15","doi-asserted-by":"publisher","first-page":"S44","DOI":"10.1097\/WAD.0b013e31815c3486","volume":"21","author":"IR Mackenzie","year":"2007","unstructured":"Mackenzie IR (2007) The neuropathology of FTD associated With ALS. Alzheimer Dis Assoc Disord 21:S44\u2013S49","journal-title":"Alzheimer Dis Assoc Disord"},{"key":"1171_CR16","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1007\/s00401-008-0460-5","volume":"117","author":"IR Mackenzie","year":"2009","unstructured":"Mackenzie IR, Neumann M, Bigio EH et al (2009) Nomenclature for neuropathologic subtypes of frontotemporal lobar degeneration: consensus recommendations. Acta Neuropathol 117:15\u201318","journal-title":"Acta Neuropathol"},{"key":"1171_CR17","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s00401-009-0612-2","volume":"119","author":"IR Mackenzie","year":"2010","unstructured":"Mackenzie IR, Neumann M, Bigio EH et al (2010) Nomenclature and nosology for neuropathologic subtypes of frontotemporal lobar degeneration: an update. Acta Neuropathol 119:1\u20134","journal-title":"Acta Neuropathol"},{"key":"1171_CR18","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1159\/000007961","volume":"40","author":"JA Molina","year":"1998","unstructured":"Molina JA, Probst A, Villanueva C et al (1998) Primary progressive aphasia with glial cytoplasmic inclusions. Eur Neurol 40:71\u201377","journal-title":"Eur Neurol"},{"key":"1171_CR19","doi-asserted-by":"publisher","first-page":"2657","DOI":"10.1093\/brain\/awh303","volume":"127","author":"T Ozawa","year":"2004","unstructured":"Ozawa T, Paviour D, Quinn NP et al (2004) The spectrum of pathological involvement of the striatonigral and olivopontocerebellar systems in multiple system atrophy: clinicopathological correlations. Brain 127:2657\u20132671","journal-title":"Brain"},{"key":"1171_CR20","doi-asserted-by":"publisher","first-page":"600","DOI":"10.1007\/s00401-005-1086-5","volume":"110","author":"YS Piao","year":"2005","unstructured":"Piao YS, Tan CF, Iwanaga K et al (2005) Sporadic four-repeat tauopathy with frontotemporal degeneration, parkinsonism and motor neuron disease. Acta Neuropathol 110:600\u2013609","journal-title":"Acta Neuropathol"},{"key":"1171_CR21","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1007\/s00401-003-0719-9","volume":"106","author":"JM Powers","year":"2003","unstructured":"Powers JM, Byrne NP, Ito M et al (2003) A novel leukoencephalopathy associated with tau deposits primarily in white matter glia. Acta Neuropathol 106:181\u2013187","journal-title":"Acta Neuropathol"},{"key":"1171_CR22","doi-asserted-by":"publisher","first-page":"4113","DOI":"10.1073\/pnas.94.8.4113","volume":"94","author":"MG Spillantini","year":"1997","unstructured":"Spillantini MG, Goedert M, Crowther RA, Murrell JR, Farlow MR, Ghetti B (1997) Familial multiple system tauopathy with presenile dementia: a disease with abundant neuronal and glial tau filaments. Proc Natl Acad Sci USA 94:4113\u20134118","journal-title":"Proc Natl Acad Sci USA"},{"key":"1171_CR23","doi-asserted-by":"publisher","first-page":"7737","DOI":"10.1073\/pnas.95.13.7737","volume":"95","author":"MG Spillantini","year":"1998","unstructured":"Spillantini MG, Murrell JR, Goedert M, Farlow MR, Klug A, Ghetti B (1998) Mutation in the tau gene in familial multiple system tauopathy with presenile dementia. Proc Natl Acad Sci USA 95:7737\u20137741","journal-title":"Proc Natl Acad Sci USA"},{"key":"1171_CR24","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1093\/brain\/awm280","volume":"131","author":"S Spina","year":"2008","unstructured":"Spina S, Farlow MR, Unverzagt FW et al (2008) The tauopathy associated with mutation +3 in intron 10 of Tau: characterization of the MSTD family. Brain 131:72\u201389","journal-title":"Brain"},{"key":"1171_CR25","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1002\/9781444341256.ch17","volume-title":"Neurodegeneration: the molecular pathology of dementia and movement disorders","author":"M Tolnay","year":"2011","unstructured":"Tolnay M, Braak H (2011) Argyrophilic grain disease. In: Dickson DW, Weller RO (eds) Neurodegeneration: the molecular pathology of dementia and movement disorders, 2nd edn. Wiley-Blackwell, Chichester, West Sussex, pp 165\u2013170","edition":"2"},{"key":"1171_CR26","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1002\/ana.21465","volume":"64","author":"GK Wenning","year":"2008","unstructured":"Wenning GK, Stefanova N, Jellinger KA, Poewe W, Schlossmacher MG (2008) Multiple system atrophy: a primary oligodendrogliopathy. Ann Neurol 64:239\u2013246","journal-title":"Ann Neurol"},{"key":"1171_CR27","doi-asserted-by":"publisher","first-page":"2343","DOI":"10.1111\/j.1471-4159.2008.05321.x","volume":"105","author":"S Wray","year":"2008","unstructured":"Wray S, Saxton M, Anderton BH, Hanger DP (2008) Direct analysis of tau from PSP brain identifies new phosphorylation sites and a major fragment of N-terminally cleaved tau containing four microtubule-binding repeats. J Neurochem 105:2343\u20132352","journal-title":"J Neurochem"}],"container-title":["Acta Neuropathologica"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00401-013-1171-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00401-013-1171-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00401-013-1171-0","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00401-013-1171-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,2,18]],"date-time":"2020-02-18T01:32:48Z","timestamp":1581989568000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00401-013-1171-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,8,31]]},"references-count":27,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2013,10]]}},"alternative-id":["1171"],"URL":"https:\/\/doi.org\/10.1007\/s00401-013-1171-0","relation":{},"ISSN":["0001-6322","1432-0533"],"issn-type":[{"value":"0001-6322","type":"print"},{"value":"1432-0533","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,8,31]]}}}