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In addition, he has received commercial support for grants\/research from Renovo and Teva\/Lundbeck. Dr. Brundin has ownership interests in Acousort AB and Parkcell AB. Dr. Trojanowski serves as an Associate Editor of Alzheimer\u2019s & Dementia. He may accrue revenue on patents submitted by the University of Pennsylvania wherein he is inventor including: Modified avidin\u2013biotin technique, Method of stabilizing microtubules to treat Alzheimer\u2019s disease, Method of detecting abnormally phosphorylated tau, Method of screening for Alzheimer\u2019s disease or disease associated with the accumulation of paired helical filaments, Compositions and methods for producing and using homogeneous neuronal cell transplants, Rat comprising straight filaments in its brain, Compositions and methods for producing and using homogeneous neuronal cell transplants to treat neurodegenerative disorders and brain and spinal cord injuries, Diagnostic methods for Alzheimer\u2019s disease by detection of multiple MRNAs, Methods and compositions for determining lipid peroxidation levels in oxidant stress syndromes and diseases, Compositions and methods for producing and using homogenous neuronal cell transplants, Method of identifying, diagnosing and treating alpha-synuclein positive neurodegenerative disorders, Mutation-specific functional impairments in distinct tau isoforms of hereditary frontotemporal dementia and parkinsonism linked to chromosome-17: genotype predicts phenotype, Microtubule stabilizing therapies for neurodegenerative disorders, and Treatment of Alzheimer\u2019s and related diseases with an antibody. He is co-inventor on patents submitted the University of Pennsylvania wherein he is inventor that has generated income he has received from the sale of Avid to Eli Lily including: Amyloid plaque aggregation inhibitors and diagnostic imaging agents. Dr. Lee has received funding for travel and honoraria from Takeda Pharmaceutical Company Ltd.; has received speaker honoraria from Pfizer Inc., BMS, and Merck; may accrue revenue on patents re: Modified avidin\u2013biotin technique, Method of stabilizing microtubules to treat Alzheimer\u2019s disease, Method of detecting abnormally phosphorylated tau, Method of screening for Alzheimer\u2019s disease or disease associated with the accumulation of paired helical filaments, Compositions and methods for producing and using homogeneous neuronal cell transplants, Rat comprising straight filaments in its brain, Compositions and methods for producing and using homogeneous neuronal cell transplants to treat neurodegenerative disorders and brain and spinal cord injuries, Diagnostic methods for Alzheimer\u2019s disease by detection of multiple MRNAs, Methods and compositions for determining lipid peroxidation levels in oxidant stress syndromes and diseases, Compositions and methods for producing and using homogenous neuronal cell transplants, Method of identifying, diagnosing and treating alpha-synuclein positive neurodegenerative disorders, Mutation-specific functional impairments in distinct tau isoforms of hereditary frontotemporal dementia and parkinsonism linked to chromosome-17: genotype predicts phenotype, Microtubule stabilizing therapies for neurodegenerative disorders, and Treatment of Alzheimer\u2019s and related diseases with an antibody; and receives research support from the NIH NIA PO1 AG 17586-12, PO1 AG-032953, NINDS P50 NS053488-02, NIA UO1 AG029213-01; and from the Marian S. Ware Alzheimer Program. The authors declare no additional competing financial interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The housing of the animals and all procedures were in accordance with the European international guidelines, with the Guide for the Care and Use of Laboratory Animals (US National Institutes of Health) and were approved by the Malm\u00f6-Lund Ethical Committee for Animal research (M109-13) and Van Andel Research Institute\u2019s IACUC (AUP 14-01-001). This article does not contain any studies with human participants performed by any of the authors (research on tissue derived from an autopsy is not considered as human subject research). For the post-mortem human brain tissue, a consent for autopsy was obtained from the next-of-kin at the time of the death.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval and consent to participate"}}]}}