{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T21:42:35Z","timestamp":1793050955916,"version":"4.5.0"},"reference-count":8,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2020,8,8]],"date-time":"2020-08-08T00:00:00Z","timestamp":1596844800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,8,8]],"date-time":"2020-08-08T00:00:00Z","timestamp":1596844800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/100012524","name":"American Lebanese Syrian Associated Charities","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100012524","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"crossref","award":["P30CA021765"],"award-info":[{"award-number":["P30CA021765"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Acta Neuropathol"],"published-print":{"date-parts":[[2020,10]]},"DOI":"10.1007\/s00401-020-02208-9","type":"journal-article","created":{"date-parts":[[2020,8,8]],"date-time":"2020-08-08T16:02:27Z","timestamp":1596902547000},"page":"595-597","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["WNT-activated embryonal tumors of the pineal region: ectopic medulloblastomas or a novel pineoblastoma subgroup?"],"prefix":"10.1007","volume":"140","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8597-9128","authenticated-orcid":false,"given":"Anthony P. Y.","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Loudy P.","family":"Priesterbach-Ackley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brent A.","family":"Orr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bryan K.","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian","family":"Gudenas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roel E.","family":"Reddingius","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariona","family":"Su\u00f1ol","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cinzia E.","family":"Lavarino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nagore G.","family":"Olaciregui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vicente","family":"Santa-Mar\u00eda L\u00f3pez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael J.","family":"Fisher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lili-Naz","family":"Hazrati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Bouffet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annie","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giles W.","family":"Robinson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pieter","family":"Wesseling","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul A.","family":"Northcott","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amar","family":"Gajjar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,8,8]]},"reference":[{"key":"2208_CR1","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1038\/nrc3419","volume":"13","author":"JN Anastas","year":"2013","unstructured":"Anastas JN, Moon RT (2013) WNT signalling pathways as therapeutic targets in cancer. Nat Rev Cancer 13:11\u201326. https:\/\/doi.org\/10.1038\/nrc3419","journal-title":"Nat Rev Cancer"},{"key":"2208_CR2","doi-asserted-by":"publisher","first-page":"469","DOI":"10.1038\/nature26000","volume":"555","author":"D Capper","year":"2018","unstructured":"Capper D, Jones DT, Sill M, Hovestadt V, Schrimpf D, Sturm D et al (2018) DNA methylation-based classification of central nervous system tumours. Nature 555:469\u2013474","journal-title":"Nature"},{"key":"2208_CR3","doi-asserted-by":"publisher","first-page":"1095","DOI":"10.1038\/nature09587","volume":"468","author":"P Gibson","year":"2010","unstructured":"Gibson P, Tong Y, Robinson G, Thompson MC, Currle DS, Eden C et al (2010) Subtypes of medulloblastoma have distinct developmental origins. Nature 468:1095\u20131099. https:\/\/doi.org\/10.1038\/nature09587","journal-title":"Nature"},{"key":"2208_CR4","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1007\/s00401-019-02111-y","volume":"139","author":"BK Li","year":"2020","unstructured":"Li BK, Vasiljevic A, Dufour C, Yao F, Ho BLB, Lu M et al (2020) Pineoblastoma segregates into molecular sub-groups with distinct clinico-pathologic features: a Rare Brain Tumor Consortium registry study. Acta Neuropathol 139:223\u2013241. https:\/\/doi.org\/10.1007\/s00401-019-02111-y","journal-title":"Acta Neuropathol"},{"key":"2208_CR5","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1007\/s00401-019-02106-9","volume":"139","author":"APY Liu","year":"2020","unstructured":"Liu APY, Gudenas B, Lin T, Orr BA, Klimo P, Kumar R et al (2020) Risk-adapted therapy and biological heterogeneity in pineoblastoma: integrated clinico-pathological analysis from the prospective, multi-center SJMB03 and SJYC07 trials. Acta Neuropathol 139:259\u2013271. https:\/\/doi.org\/10.1007\/s00401-019-02106-9","journal-title":"Acta Neuropathol"},{"key":"2208_CR6","doi-asserted-by":"publisher","first-page":"1724","DOI":"10.1242\/dev.050104","volume":"139","author":"Y Pei","year":"2012","unstructured":"Pei Y, Brun SN, Markant SL, Lento W, Gibson P, Taketo MM et al (2012) WNT signaling increases proliferation and impairs differentiation of stem cells in the developing cerebellum. Development 139:1724\u20131733. https:\/\/doi.org\/10.1242\/dev.050104","journal-title":"Development"},{"key":"2208_CR7","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1007\/s00401-019-02101-0","volume":"139","author":"E Pfaff","year":"2020","unstructured":"Pfaff E, Aichm\u00fcller C, Sill M, Stichel D, Snuderl M, Karajannis MA et al (2020) Molecular subgrouping of primary pineal parenchymal tumors reveals distinct subtypes correlated with clinical parameters and genetic alterations. Acta Neuropathol 139:243\u2013257. https:\/\/doi.org\/10.1007\/s00401-019-02101-0","journal-title":"Acta Neuropathol"},{"key":"2208_CR8","doi-asserted-by":"publisher","first-page":"478","DOI":"10.1111\/nan.12610","volume":"46","author":"LP Priesterbach-Ackley","year":"2020","unstructured":"Priesterbach-Ackley LP, Boldt HB, Petersen JK, Bervoets N, Scheie D, Ulh\u00f8i BP et al (2020) Brain tumour diagnostics using a DNA methylation-based classifier as a diagnostic support tool. Neuropathol Appl Neurobiol 46:478\u2013492. https:\/\/doi.org\/10.1111\/nan.12610","journal-title":"Neuropathol Appl Neurobiol"}],"container-title":["Acta Neuropathologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00401-020-02208-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00401-020-02208-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00401-020-02208-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,7]],"date-time":"2021-08-07T19:18:51Z","timestamp":1628363931000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00401-020-02208-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8,8]]},"references-count":8,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020,10]]}},"alternative-id":["2208"],"URL":"https:\/\/doi.org\/10.1007\/s00401-020-02208-9","relation":{},"ISSN":["0001-6322","1432-0533"],"issn-type":[{"value":"0001-6322","type":"print"},{"value":"1432-0533","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8,8]]},"assertion":[{"value":"24 June 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 July 2020","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 August 2020","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 August 2020","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}