{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T03:04:15Z","timestamp":1740107055736,"version":"3.37.3"},"reference-count":8,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2022,11,6]],"date-time":"2022-11-06T00:00:00Z","timestamp":1667692800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,11,6]],"date-time":"2022-11-06T00:00:00Z","timestamp":1667692800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Acta Neuropathol"],"published-print":{"date-parts":[[2023,2]]},"DOI":"10.1007\/s00401-022-02517-1","type":"journal-article","created":{"date-parts":[[2022,11,6]],"date-time":"2022-11-06T07:02:25Z","timestamp":1667718145000},"page":"257-258","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["More than a co-incidence? Comment on: Amyotrophic lateral sclerosis is over\u2010represented in two Huntington\u2019s disease brain bank cohorts: further evidence to support genetic pleiotropy of pathogenic HTT gene expansion"],"prefix":"10.1007","volume":"145","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8469-043X","authenticated-orcid":false,"given":"Hannah S.","family":"Bakels","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephanie","family":"Feleus","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vera","family":"van Dis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susanne T.","family":"de Bot","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,11,6]]},"reference":[{"key":"2517_CR1","doi-asserted-by":"publisher","first-page":"2107","DOI":"10.1212\/01.wnl.0000437313.80913.2c","volume":"81","author":"P Bede","year":"2013","unstructured":"Bede P, Elamin M, Byrne S, McLaughlin RL, Kenna K, Vajda A et al (2013) Basal ganglia involvement in amyotrophic lateral sclerosis. Neurology 81:2107\u20132115. https:\/\/doi.org\/10.1212\/01.wnl.0000437313.80913.2c","journal-title":"Neurology"},{"key":"2517_CR2","doi-asserted-by":"publisher","first-page":"338","DOI":"10.1136\/jnnp.33.3.338","volume":"33","author":"B Brownell","year":"1970","unstructured":"Brownell B, Oppenheimer DR, Hughes JT (1970) The central nervous system in motor neurone disease. J Neurol Neurosurg Psychiatry 33:338\u2013357. https:\/\/doi.org\/10.1136\/jnnp.33.3.338","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"2517_CR3","doi-asserted-by":"publisher","first-page":"448","DOI":"10.1016\/j.neuron.2020.11.005","volume":"109","author":"R Dewan","year":"2021","unstructured":"Dewan R, Chia R, Ding J, Hickman RA, Stein TD, Abramzon Y et al (2021) Pathogenic huntingtin repeat expansions in patients with frontotemporal dementia and amyotrophic lateral sclerosis. Neuron 109:448-460.e444. https:\/\/doi.org\/10.1016\/j.neuron.2020.11.005","journal-title":"Neuron"},{"key":"2517_CR4","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1007\/s00401-021-02385-1","volume":"143","author":"RA Hickman","year":"2022","unstructured":"Hickman RA, Dewan R, Cortes E, Traynor BJ, Marder K, Vonsattel JP (2022) Amyotrophic lateral sclerosis is over-represented in two Huntington\u2019s disease brain bank cohorts: further evidence to support genetic pleiotropy of pathogenic HTT gene expansion. Acta Neuropathol 143:105\u2013108. https:\/\/doi.org\/10.1007\/s00401-021-02385-1","journal-title":"Acta Neuropathol"},{"key":"2517_CR5","doi-asserted-by":"publisher","first-page":"1285","DOI":"10.15585\/mmwr.mm6746a1","volume":"67","author":"P Mehta","year":"2018","unstructured":"Mehta P, Kaye W, Raymond J, Punjani R, Larson T, Cohen J et al (2018) Prevalence of amyotrophic lateral sclerosis\u2014United States, 2015. MMWR Morb Mortal Wkly Rep 67:1285\u20131289. https:\/\/doi.org\/10.15585\/mmwr.mm6746a1","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"2517_CR6","doi-asserted-by":"publisher","first-page":"801","DOI":"10.1093\/jnen\/nlw053","volume":"75","author":"Y Riku","year":"2016","unstructured":"Riku Y, Watanabe H, Yoshida M, Mimuro M, Iwasaki Y, Masuda M et al (2016) Marked involvement of the striatal efferent system in TAR DNA-binding protein 43 kDa-related frontotemporal lobar degeneration and amyotrophic lateral sclerosis. J Neuropathol Exp Neurol 75:801\u2013811. https:\/\/doi.org\/10.1093\/jnen\/nlw053","journal-title":"J Neuropathol Exp Neurol"},{"key":"2517_CR7","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1111\/bpa.12115","volume":"24","author":"U R\u00fcb","year":"2014","unstructured":"R\u00fcb U, Hentschel M, Stratmann K, Brunt E, Heinsen H, Seidel K et al (2014) Huntington\u2019s disease (HD): degeneration of select nuclei, widespread occurrence of neuronal nuclear and axonal inclusions in the brainstem. Brain Pathol (Zurich, Switzerland) 24:247\u2013260. https:\/\/doi.org\/10.1111\/bpa.12115","journal-title":"Brain Pathol (Zurich, Switzerland)"},{"key":"2517_CR8","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1007\/s00401-017-1786-7","volume":"135","author":"I St-Amour","year":"2018","unstructured":"St-Amour I, Turgeon A, Goupil C, Planel E, H\u00e9bert SS (2018) Co-occurrence of mixed proteinopathies in late-stage Huntington\u2019s disease. Acta Neuropathol 135:249\u2013265. https:\/\/doi.org\/10.1007\/s00401-017-1786-7","journal-title":"Acta Neuropathol"}],"container-title":["Acta Neuropathologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00401-022-02517-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00401-022-02517-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00401-022-02517-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,18]],"date-time":"2023-01-18T14:12:54Z","timestamp":1674051174000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00401-022-02517-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11,6]]},"references-count":8,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023,2]]}},"alternative-id":["2517"],"URL":"https:\/\/doi.org\/10.1007\/s00401-022-02517-1","relation":{},"ISSN":["0001-6322","1432-0533"],"issn-type":[{"type":"print","value":"0001-6322"},{"type":"electronic","value":"1432-0533"}],"subject":[],"published":{"date-parts":[[2022,11,6]]},"assertion":[{"value":"14 October 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 October 2022","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 October 2022","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 November 2022","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}