{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T19:10:25Z","timestamp":1792782625601,"version":"4.5.0"},"reference-count":92,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,4,24]],"date-time":"2024-04-24T00:00:00Z","timestamp":1713916800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,4,24]],"date-time":"2024-04-24T00:00:00Z","timestamp":1713916800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP20K07899"],"award-info":[{"award-number":["JP20K07899"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP23K06923"],"award-info":[{"award-number":["JP23K06923"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP21K07412"],"award-info":[{"award-number":["JP21K07412"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"name":"MHLW Research Program on Rare and Intractable Diseases","award":["JPMH 20FC1030"],"award-info":[{"award-number":["JPMH 20FC1030"]}]},{"name":"MHLW Research Program on Rare and Intractable Diseases","award":["JPMH 23FC1009"],"award-info":[{"award-number":["JPMH 23FC1009"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Acta Neuropathol"],"published-print":{"date-parts":[[2024,6]]},"DOI":"10.1007\/s00401-024-02725-x","type":"journal-article","created":{"date-parts":[[2024,4,24]],"date-time":"2024-04-24T14:01:48Z","timestamp":1713967308000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Stage-dependent immunity orchestrates AQP4 antibody-guided NMOSD pathology: a role for netting neutrophils with resident memory T cells in situ"],"prefix":"10.1007","volume":"147","author":[{"given":"Akihiro","family":"Nakajima","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fumihiro","family":"Yanagimura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Etsuji","family":"Saji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Shimizu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuko","family":"Toyoshima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaori","family":"Yanagawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Musashi","family":"Arakawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariko","family":"Hokari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akiko","family":"Yokoseki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takahiro","family":"Wakasugi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kouichirou","family":"Okamoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hirohide","family":"Takebayashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chihiro","family":"Fujii","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyoko","family":"Itoh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yo-ichi","family":"Takei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinji","family":"Ohara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitsunori","family":"Yamada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hitoshi","family":"Takahashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masatoyo","family":"Nishizawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hironaka","family":"Igarashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akiyoshi","family":"Kakita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Osamu","family":"Onodera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7140-8500","authenticated-orcid":false,"given":"Izumi","family":"Kawachi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,4,24]]},"reference":[{"key":"2725_CR1","doi-asserted-by":"publisher","first-page":"2856","DOI":"10.1038\/s41467-020-16625-7","volume":"11","author":"AM Agasing","year":"2020","unstructured":"Agasing AM, Wu Q, Khatri B, Borisow N, Ruprecht K, Brandt AU et al (2020) Transcriptomics and proteomics reveal a cooperation between interferon and T-helper 17 cells in neuromyelitis optica. Nat Commun 11:2856. https:\/\/doi.org\/10.1038\/s41467-020-16625-7","journal-title":"Nat Commun"},{"key":"2725_CR2","doi-asserted-by":"publisher","first-page":"1954","DOI":"10.4049\/jimmunol.1400478","volume":"193","author":"M Behnen","year":"2014","unstructured":"Behnen M, Leschczyk C, M\u00f6ller S, Batel T, Klinger M, Solbach W et al (2014) Immobilized immune complexes induce neutrophil extracellular trap release by human neutrophil granulocytes via Fc\u03b3RIIIB and Mac-1. J Immunol 193:1954\u20131965. https:\/\/doi.org\/10.4049\/jimmunol.1400478","journal-title":"J Immunol"},{"key":"2725_CR3","doi-asserted-by":"publisher","first-page":"4758","DOI":"10.1172\/JCI128475","volume":"129","author":"E Beltran","year":"2019","unstructured":"Beltran E, Gerdes LA, Hansen J, Flierl-Hecht A, Krebs S, Blum H et al (2019) Early adaptive immune activation detected in monozygotic twins with prodromal multiple sclerosis. J Clin Investig 129:4758\u20134768. https:\/\/doi.org\/10.1172\/JCI128475","journal-title":"J Clin Investig"},{"key":"2725_CR4","doi-asserted-by":"publisher","first-page":"395","DOI":"10.1038\/s41418-018-0261-x","volume":"26","author":"S Boeltz","year":"2019","unstructured":"Boeltz S, Amini P, Anders HJ, Andrade F, Bilyy R, Chatfield S et al (2019) To NET or not to NET:current opinions and state of the science regarding the formation of neutrophil extracellular traps. Cell Death Differ 26:395\u2013408. https:\/\/doi.org\/10.1038\/s41418-018-0261-x","journal-title":"Cell Death Differ"},{"key":"2725_CR5","doi-asserted-by":"publisher","first-page":"773","DOI":"10.1083\/jcb.201203170","volume":"198","author":"V Brinkmann","year":"2012","unstructured":"Brinkmann V, Zychlinsky A (2012) Neutrophil extracellular traps: is immunity the second function of chromatin? J Cell Biol 198:773\u2013783. https:\/\/doi.org\/10.1083\/jcb.201203170","journal-title":"J Cell Biol"},{"key":"2725_CR6","doi-asserted-by":"publisher","first-page":"3329","DOI":"10.1093\/brain\/awp289","volume":"132","author":"V Brucklacher-Waldert","year":"2009","unstructured":"Brucklacher-Waldert V, Stuerner K, Kolster M, Wolthausen J, Tolosa E (2009) Phenotypical and functional characterization of T helper 17 cells in multiple sclerosis. Brain 132:3329\u20133341. https:\/\/doi.org\/10.1093\/brain\/awp289","journal-title":"Brain"},{"key":"2725_CR7","doi-asserted-by":"publisher","first-page":"1076","DOI":"10.1038\/s41590-023-01538-6","volume":"24","author":"M Buggert","year":"2023","unstructured":"Buggert M, Price DA, Mackay LK, Betts MR (2023) Human circulating and tissue-resident memory CD8(+) T cells. Nat Immunol 24:1076\u20131086. https:\/\/doi.org\/10.1038\/s41590-023-01538-6","journal-title":"Nat Immunol"},{"key":"2725_CR8","doi-asserted-by":"publisher","first-page":"492","DOI":"10.1177\/13524585221113272","volume":"29","author":"E Carnero Contentti","year":"2023","unstructured":"Carnero Contentti E, Correale J (2023) Association between infections, the microbiome, vaccination, and neuromyelitis optica spectrum disorder. Mult Scler 29:492\u2013501. https:\/\/doi.org\/10.1177\/13524585221113272","journal-title":"Mult Scler"},{"key":"2725_CR9","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1016\/j.neurad.2008.12.008","volume":"36","author":"C Cassinotto","year":"2009","unstructured":"Cassinotto C, Deramond H, Olindo S, Aveillan M, Smadja D, Cabre P (2009) MRI of the spinal cord in neuromyelitis optica and recurrent longitudinal extensive myelitis. J Neuroradiol 36:199\u2013205. https:\/\/doi.org\/10.1016\/j.neurad.2008.12.008","journal-title":"J Neuroradiol"},{"key":"2725_CR10","doi-asserted-by":"publisher","first-page":"1483","DOI":"10.1093\/brain\/awac389","volume":"146","author":"M Charabati","year":"2023","unstructured":"Charabati M, Zandee S, Fournier AP, Tastet O, Thai K, Zaminpeyma R et al (2023) MCAM+ brain endothelial cells contribute to neuroinflammation by recruiting pathogenic CD4+ T lymphocytes. Brain 146:1483\u20131495. https:\/\/doi.org\/10.1093\/brain\/awac389","journal-title":"Brain"},{"key":"2725_CR11","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1016\/j.immuni.2017.01.009","volume":"46","author":"S Cheuk","year":"2017","unstructured":"Cheuk S, Schlums H, Gallais Serezal I, Martini E, Chiang SC, Marquardt N et al (2017) CD49a Expression Defines Tissue-Resident CD8(+) T Cells Poised for Cytotoxic Function in Human Skin. Immunity 46:287\u2013300. https:\/\/doi.org\/10.1016\/j.immuni.2017.01.009","journal-title":"Immunity"},{"key":"2725_CR12","doi-asserted-by":"publisher","first-page":"1352","DOI":"10.1016\/S0140-6736(19)31817-3","volume":"394","author":"BAC Cree","year":"2019","unstructured":"Cree BAC, Bennett JL, Kim HJ, Weinshenker BG, Pittock SJ, Wingerchuk DM et al (2019) Inebilizumab for the treatment of neuromyelitis optica spectrum disorder (N-MOmentum): a double-blind, randomised placebo-controlled phase 2\/3 trial. Lancet 394:1352\u20131363. https:\/\/doi.org\/10.1016\/S0140-6736(19)31817-3","journal-title":"Lancet"},{"key":"2725_CR13","doi-asserted-by":"publisher","first-page":"559","DOI":"10.1038\/s41581-019-0163-2","volume":"15","author":"C Daniel","year":"2019","unstructured":"Daniel C, Leppkes M, Munoz LE, Schley G, Schett G, Herrmann M (2019) Extracellular DNA traps in inflammation, injury and healing. Nat Rev Nephrol 15:559\u2013575. https:\/\/doi.org\/10.1038\/s41581-019-0163-2","journal-title":"Nat Rev Nephrol"},{"key":"2725_CR14","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2022.111963","volume":"42","author":"JW Dean","year":"2023","unstructured":"Dean JW, Helm EY, Fu Z, Xiong L, Sun N, Oliff KN et al (2023) The aryl hydrocarbon receptor cell intrinsically promotes resident memory CD8(+) T cell differentiation and function. Cell Rep 42:111963. https:\/\/doi.org\/10.1016\/j.celrep.2022.111963","journal-title":"Cell Rep"},{"key":"2725_CR15","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1111\/bpa.12793","volume":"30","author":"T Duan","year":"2020","unstructured":"Duan T, Verkman AS (2020) Experimental animal models of aquaporin-4-IgG-seropositive neuromyelitis optica spectrum disorders: progress and shortcomings. Brain Pathol 30:13\u201325. https:\/\/doi.org\/10.1111\/bpa.12793","journal-title":"Brain Pathol"},{"key":"2725_CR16","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1186\/s12974-016-0746-9","volume":"13","author":"CM Felix","year":"2016","unstructured":"Felix CM, Levin MH, Verkman AS (2016) Complement-independent retinal pathology produced by intravitreal injection of neuromyelitis optica immunoglobulin G. J Neuroinflammation 13:275. https:\/\/doi.org\/10.1186\/s12974-016-0746-9","journal-title":"J Neuroinflammation"},{"key":"2725_CR17","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0040443","volume":"7","author":"K Flanagan","year":"2012","unstructured":"Flanagan K, Fitzgerald K, Baker J, Regnstrom K, Gardai S, Bard F et al (2012) Laminin-411 is a vascular ligand for MCAM and facilitates TH17 cell entry into the CNS. PLoS ONE 7:e40443. https:\/\/doi.org\/10.1371\/journal.pone.0040443","journal-title":"PLoS ONE"},{"key":"2725_CR18","doi-asserted-by":"publisher","DOI":"10.3390\/cells9040915","author":"E Fousert","year":"2020","unstructured":"Fousert E, Toes R, Desai J (2020) Neutrophil Extracellular Traps (NETs) Take the Central Stage in Driving Autoimmune Responses. Cells. https:\/\/doi.org\/10.3390\/cells9040915","journal-title":"Cells"},{"key":"2725_CR19","doi-asserted-by":"publisher","first-page":"1714","DOI":"10.1093\/brain\/awaa117","volume":"143","author":"NL Fransen","year":"2020","unstructured":"Fransen NL, Hsiao CC, van der Poel M, Engelenburg HJ, Verdaasdonk K, Vincenten MCJ et al (2020) Tissue-resident memory T cells invade the brain parenchyma in multiple sclerosis white matter lesions. Brain 143:1714\u20131730. https:\/\/doi.org\/10.1093\/brain\/awaa117","journal-title":"Brain"},{"key":"2725_CR20","doi-asserted-by":"publisher","first-page":"6157","DOI":"10.1126\/scitranslmed.abl6157","volume":"14","author":"D Frieser","year":"2022","unstructured":"Frieser D, Pignata A, Khajavi L, Shlesinger D, Gonzalez-Fierro C, Nguyen XH et al (2022) Tissue-resident CD8(+) T cells drive compartmentalized and chronic autoimmune damage against CNS neurons. Science translational medicine 14:6157. https:\/\/doi.org\/10.1126\/scitranslmed.abl6157","journal-title":"Science translational medicine"},{"key":"2725_CR21","doi-asserted-by":"publisher","first-page":"7320","DOI":"10.1126\/scitranslmed.3001201","volume":"3","author":"GS Garcia-Romo","year":"2011","unstructured":"Garcia-Romo GS, Caielli S, Vega B, Connolly J, Allantaz F, Xu Z et al (2011) Netting neutrophils are major inducers of type I IFN production in pediatric systemic lupus erythematosus. Science translational medicine 3:7320. https:\/\/doi.org\/10.1126\/scitranslmed.3001201","journal-title":"Science translational medicine"},{"key":"2725_CR22","doi-asserted-by":"publisher","DOI":"10.1002\/eji.202149775","volume":"53","author":"J Geginat","year":"2023","unstructured":"Geginat J, Vasco C, Gruarin P, Bonnal R, Rossetti G, Silvestri Y et al (2023) Eomesodermin-expressing type 1 regulatory (EOMES(+) Tr1)-like T cells: Basic biology and role in immune-mediated diseases. Eur J Immunol 53:e2149775. https:\/\/doi.org\/10.1002\/eji.202149775","journal-title":"Eur J Immunol"},{"key":"2725_CR23","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1016\/j.jns.2013.02.024","volume":"328","author":"V Gredler","year":"2013","unstructured":"Gredler V, Mader S, Schanda K, Hegen H, Di Pauli F, Kuenz B et al (2013) Clinical and immunological follow-up of B-cell depleting therapy in CNS demyelinating diseases. J Neurol Sci 328:77\u201382. https:\/\/doi.org\/10.1016\/j.jns.2013.02.024","journal-title":"J Neurol Sci"},{"key":"2725_CR24","doi-asserted-by":"publisher","first-page":"848","DOI":"10.1002\/ana.23974","volume":"74","author":"S Hametner","year":"2013","unstructured":"Hametner S, Wimmer I, Haider L, Pfeifenbring S, Bruck W, Lassmann H (2013) Iron and neurodegeneration in the multiple sclerosis brain. Ann Neurol 74:848\u2013861. https:\/\/doi.org\/10.1002\/ana.23974","journal-title":"Ann Neurol"},{"key":"2725_CR25","doi-asserted-by":"publisher","first-page":"794","DOI":"10.1002\/ana.24630","volume":"79","author":"M Herwerth","year":"2016","unstructured":"Herwerth M, Kalluri SR, Srivastava R, Kleele T, Kenet S, Illes Z et al (2016) In vivo imaging reveals rapid astrocyte depletion and axon damage in a model of neuromyelitis optica-related pathology. Ann Neurol 79:794\u2013805. https:\/\/doi.org\/10.1002\/ana.24630","journal-title":"Ann Neurol"},{"key":"2725_CR26","doi-asserted-by":"publisher","first-page":"1164","DOI":"10.1001\/archneurol.2009.188","volume":"66","author":"SR Hinson","year":"2009","unstructured":"Hinson SR, McKeon A, Fryer JP, Apiwattanakul M, Lennon VA, Pittock SJ (2009) Prediction of neuromyelitis optica attack severity by quantitation of complement-mediated injury to aquaporin-4-expressing cells. Arch Neurol 66:1164\u20131167. https:\/\/doi.org\/10.1001\/archneurol.2009.188","journal-title":"Arch Neurol"},{"key":"2725_CR27","doi-asserted-by":"publisher","first-page":"1245","DOI":"10.1073\/pnas.1109980108","volume":"109","author":"SR Hinson","year":"2012","unstructured":"Hinson SR, Romero MF, Popescu BF, Lucchinetti CF, Fryer JP, Wolburg H et al (2012) Molecular outcomes of neuromyelitis optica (NMO)-IgG binding to aquaporin-4 in astrocytes. Proc Natl Acad Sci U S A 109:1245\u20131250. https:\/\/doi.org\/10.1073\/pnas.1109980108","journal-title":"Proc Natl Acad Sci U S A"},{"key":"2725_CR28","doi-asserted-by":"publisher","first-page":"605","DOI":"10.1002\/ana.24608","volume":"79","author":"M Hokari","year":"2016","unstructured":"Hokari M, Yokoseki A, Arakawa M, Saji E, Yanagawa K, Yanagimura F et al (2016) Clinicopathological features in anterior visual pathway in neuromyelitis optica. Ann Neurol 79:605\u2013624. https:\/\/doi.org\/10.1002\/ana.24608","journal-title":"Ann Neurol"},{"key":"2725_CR29","doi-asserted-by":"publisher","first-page":"1467","DOI":"10.1038\/ni.3589","volume":"17","author":"P Hombrink","year":"2016","unstructured":"Hombrink P, Helbig C, Backer RA, Piet B, Oja AE, Stark R et al (2016) Programs for the persistence, vigilance and control of human CD8(+) lung-resident memory T cells. Nat Immunol 17:1467\u20131478. https:\/\/doi.org\/10.1038\/ni.3589","journal-title":"Nat Immunol"},{"key":"2725_CR30","doi-asserted-by":"publisher","first-page":"3458","DOI":"10.1111\/ejn.12711","volume":"40","author":"M Horie","year":"2014","unstructured":"Horie M, Watanabe K, Bepari AK, Nashimoto J, Araki K, Sano H et al (2014) Disruption of actin-binding domain-containing Dystonin protein causes dystonia musculorum in mice. Eur J Neurosci 40:3458\u20133471. https:\/\/doi.org\/10.1111\/ejn.12711","journal-title":"Eur J Neurosci"},{"key":"2725_CR31","doi-asserted-by":"publisher","unstructured":"Ikeguchi R, Shimizu Y, Kondo A, Kanda N, So H, Kojima H et al (2021) Melanoma Cell Adhesion Molecule Expressing Helper T Cells in CNS Inflammatory Demyelinating Diseases. Neurology(R) neuroimmunology & neuroinflammation 8: e1069. https:\/\/doi.org\/10.1212\/NXI.0000000000001069","DOI":"10.1212\/NXI.0000000000001069"},{"key":"2725_CR32","doi-asserted-by":"publisher","first-page":"246","DOI":"10.1038\/s41586-018-0824-5","volume":"565","author":"M Ito","year":"2019","unstructured":"Ito M, Komai K, Mise-Omata S, Iizuka-Koga M, Noguchi Y, Kondo T et al (2019) Brain regulatory T cells suppress astrogliosis and potentiate neurological recovery. Nature 565:246\u2013250. https:\/\/doi.org\/10.1038\/s41586-018-0824-5","journal-title":"Nature"},{"key":"2725_CR33","doi-asserted-by":"publisher","first-page":"661","DOI":"10.1111\/bpa.12084","volume":"23","author":"S Jarius","year":"2013","unstructured":"Jarius S, Wildemann B (2013) Aquaporin-4 antibodies (NMO-IgG) as a serological marker of neuromyelitis optica: a critical review of the literature. Brain Pathol 23:661\u2013683. https:\/\/doi.org\/10.1111\/bpa.12084","journal-title":"Brain Pathol"},{"key":"2725_CR34","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1136\/jnnp-2016-313300","volume":"88","author":"I Kawachi","year":"2017","unstructured":"Kawachi I, Lassmann H (2017) Neurodegeneration in multiple sclerosis and neuromyelitis optica. J Neurol Neurosurg Psychiatry 88:137\u2013145. https:\/\/doi.org\/10.1136\/jnnp-2016-313300","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"2725_CR35","doi-asserted-by":"publisher","first-page":"1173","DOI":"10.1038\/nm1651","volume":"13","author":"H Kebir","year":"2007","unstructured":"Kebir H, Kreymborg K, Ifergan I, Dodelet-Devillers A, Cayrol R, Bernard M et al (2007) Human TH17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation. Nat Med 13:1173\u20131175. https:\/\/doi.org\/10.1038\/nm1651","journal-title":"Nat Med"},{"key":"2725_CR36","doi-asserted-by":"publisher","first-page":"623","DOI":"10.1016\/j.bbrc.2009.06.085","volume":"386","author":"M Kinoshita","year":"2009","unstructured":"Kinoshita M, Nakatsuji Y, Kimura T, Moriya M, Takata K, Okuno T et al (2009) Neuromyelitis optica: Passive transfer to rats by human immunoglobulin. Biochem Biophys Res Commun 386:623\u2013627. https:\/\/doi.org\/10.1016\/j.bbrc.2009.06.085","journal-title":"Biochem Biophys Res Commun"},{"key":"2725_CR37","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.aax2398","author":"M Kinoshita","year":"2021","unstructured":"Kinoshita M, Ogawa Y, Hama N, Ujiie I, Hasegawa A, Nakajima S et al (2021) Neutrophils initiate and exacerbate Stevens-Johnson syndrome and toxic epidermal necrolysis. Science translational medicine. https:\/\/doi.org\/10.1126\/scitranslmed.aax2398","journal-title":"Science translational medicine"},{"key":"2725_CR38","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1038\/nri.2016.144","volume":"17","author":"T Korn","year":"2017","unstructured":"Korn T, Kallies A (2017) T cell responses in the central nervous system. Nat Rev Immunol 17:179\u2013194. https:\/\/doi.org\/10.1038\/nri.2016.144","journal-title":"Nat Rev Immunol"},{"key":"2725_CR39","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1007\/s00401-016-1653-y","volume":"133","author":"T Kuhlmann","year":"2017","unstructured":"Kuhlmann T, Ludwin S, Prat A, Antel J, Bruck W, Lassmann H (2017) An updated histological classification system for multiple sclerosis lesions. Acta Neuropathol 133:13\u201324. https:\/\/doi.org\/10.1007\/s00401-016-1653-y","journal-title":"Acta Neuropathol"},{"key":"2725_CR40","doi-asserted-by":"publisher","first-page":"7319","DOI":"10.1126\/scitranslmed.3001180","volume":"3","author":"R Lande","year":"2011","unstructured":"Lande R, Ganguly D, Facchinetti V, Frasca L, Conrad C, Gregorio J et al (2011) Neutrophils activate plasmacytoid dendritic cells by releasing self-DNA-peptide complexes in systemic lupus erythematosus. Science translational medicine 3:7319. https:\/\/doi.org\/10.1126\/scitranslmed.3001180","journal-title":"Science translational medicine"},{"key":"2725_CR41","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1002\/ana.24993","volume":"82","author":"E Laridan","year":"2017","unstructured":"Laridan E, Denorme F, Desender L, Fran\u00e7ois O, Andersson T, Deckmyn H et al (2017) Neutrophil extracellular traps in ischemic stroke thrombi. Ann Neurol 82:223\u2013232. https:\/\/doi.org\/10.1002\/ana.24993","journal-title":"Ann Neurol"},{"key":"2725_CR42","doi-asserted-by":"publisher","first-page":"2906","DOI":"10.1093\/brain\/aws212","volume":"135","author":"C Larochelle","year":"2012","unstructured":"Larochelle C, Cayrol R, Kebir H, Alvarez JI, Lecuyer MA, Ifergan I et al (2012) Melanoma cell adhesion molecule identifies encephalitogenic T lymphocytes and promotes their recruitment to the central nervous system. Brain 135:2906\u20132924. https:\/\/doi.org\/10.1093\/brain\/aws212","journal-title":"Brain"},{"key":"2725_CR43","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1002\/ana.24415","volume":"78","author":"C Larochelle","year":"2015","unstructured":"Larochelle C, Lecuyer MA, Alvarez JI, Charabati M, Saint-Laurent O, Ghannam S et al (2015) Melanoma cell adhesion molecule-positive CD8 T lymphocytes mediate central nervous system inflammation. Ann Neurol 78:39\u201353. https:\/\/doi.org\/10.1002\/ana.24415","journal-title":"Ann Neurol"},{"key":"2725_CR44","doi-asserted-by":"publisher","first-page":"3522","DOI":"10.4049\/jimmunol.1102404","volume":"188","author":"J Leffler","year":"2012","unstructured":"Leffler J, Martin M, Gullstrand B, Tyden H, Lood C, Truedsson L et al (2012) Neutrophil extracellular traps that are not degraded in systemic lupus erythematosus activate complement exacerbating the disease. J Immunol 188:3522\u20133531. https:\/\/doi.org\/10.4049\/jimmunol.1102404","journal-title":"J Immunol"},{"key":"2725_CR45","doi-asserted-by":"publisher","first-page":"473","DOI":"10.1084\/jem.20050304","volume":"202","author":"VA Lennon","year":"2005","unstructured":"Lennon VA, Kryzer TJ, Pittock SJ, Verkman AS, Hinson SR (2005) IgG marker of optic-spinal multiple sclerosis binds to the aquaporin-4 water channel. J Exp Med 202:473\u2013477. https:\/\/doi.org\/10.1084\/jem.20050304","journal-title":"J Exp Med"},{"key":"2725_CR46","doi-asserted-by":"publisher","first-page":"2106","DOI":"10.1016\/S0140-6736(04)17551-X","volume":"364","author":"VA Lennon","year":"2004","unstructured":"Lennon VA, Wingerchuk DM, Kryzer TJ, Pittock SJ, Lucchinetti CF, Fujihara K et al (2004) A serum autoantibody marker of neuromyelitis optica: distinction from multiple sclerosis. Lancet 364:2106\u20132112. https:\/\/doi.org\/10.1016\/S0140-6736(04)17551-X","journal-title":"Lancet"},{"key":"2725_CR47","first-page":"573","volume":"43","author":"J Li","year":"2002","unstructured":"Li J, Patil RV, Verkman AS (2002) Mildly abnormal retinal function in transgenic mice without Muller cell aquaporin-4 water channels. Invest Ophthalmol Vis Sci 43:573\u2013579","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"2725_CR48","doi-asserted-by":"publisher","first-page":"1450","DOI":"10.1093\/brain\/awf151","volume":"125","author":"CF Lucchinetti","year":"2002","unstructured":"Lucchinetti CF, Mandler RN, McGavern D, Bruck W, Gleich G, Ransohoff RM et al (2002) A role for humoral mechanisms in the pathogenesis of Devic\u2019s neuromyelitis optica. Brain 125:1450\u20131461. https:\/\/doi.org\/10.1093\/brain\/awf151","journal-title":"Brain"},{"key":"2725_CR49","doi-asserted-by":"publisher","first-page":"2188","DOI":"10.1056\/NEJMoa1100648","volume":"365","author":"CF Lucchinetti","year":"2011","unstructured":"Lucchinetti CF, Popescu BF, Bunyan RF, Moll NM, Roemer SF, Lassmann H et al (2011) Inflammatory cortical demyelination in early multiple sclerosis. N Engl J Med 365:2188\u20132197. https:\/\/doi.org\/10.1056\/NEJMoa1100648","journal-title":"N Engl J Med"},{"key":"2725_CR50","doi-asserted-by":"publisher","first-page":"2066","DOI":"10.1093\/brain\/awy151","volume":"141","author":"J Machado-Santos","year":"2018","unstructured":"Machado-Santos J, Saji E, Troscher AR, Paunovic M, Liblau R, Gabriely G et al (2018) The compartmentalized inflammatory response in the multiple sclerosis brain is composed of tissue-resident CD8+ T lymphocytes and B cells. Brain 141:2066\u20132082. https:\/\/doi.org\/10.1093\/brain\/awy151","journal-title":"Brain"},{"key":"2725_CR51","doi-asserted-by":"publisher","first-page":"1089","DOI":"10.1093\/brain\/awm038","volume":"130","author":"R Magliozzi","year":"2007","unstructured":"Magliozzi R, Howell O, Vora A, Serafini B, Nicholas R, Puopolo M et al (2007) Meningeal B-cell follicles in secondary progressive multiple sclerosis associate with early onset of disease and severe cortical pathology. Brain 130:1089\u20131104. https:\/\/doi.org\/10.1093\/brain\/awm038","journal-title":"Brain"},{"key":"2725_CR52","doi-asserted-by":"publisher","DOI":"10.1002\/eji.202149675","volume":"53","author":"A Merino-Vico","year":"2023","unstructured":"Merino-Vico A, Frazzei G, van Hamburg JP, Tas SW (2023) Targeting B cells and plasma cells in autoimmune diseases: From established treatments to novel therapeutic approaches. Eur J Immunol 53:e2149675. https:\/\/doi.org\/10.1002\/eji.202149675","journal-title":"Eur J Immunol"},{"key":"2725_CR53","doi-asserted-by":"publisher","first-page":"1169","DOI":"10.1182\/blood.2020007008","volume":"136","author":"EA Middleton","year":"2020","unstructured":"Middleton EA, He XY, Denorme F, Campbell RA, Ng D, Salvatore SP et al (2020) Neutrophil extracellular traps contribute to immunothrombosis in COVID-19 acute respiratory distress syndrome. Blood 136:1169\u20131179. https:\/\/doi.org\/10.1182\/blood.2020007008","journal-title":"Blood"},{"key":"2725_CR54","doi-asserted-by":"publisher","unstructured":"Murata H, Kinoshita M, Yasumizu Y, Motooka D, Beppu S, Shiraishi N et al (2022) Cell-Free DNA Derived From Neutrophils Triggers Type 1 Interferon Signature in Neuromyelitis Optica Spectrum Disorder. Neurology(R) neuroimmunology & neuroinflammation 9: e1149. https:\/\/doi.org\/10.1212\/NXI.0000000000001149","DOI":"10.1212\/NXI.0000000000001149"},{"key":"2725_CR55","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1523\/JNEUROSCI.17-01-00171.1997","volume":"17","author":"S Nielsen","year":"1997","unstructured":"Nielsen S, Nagelhus EA, Amiry-Moghaddam M, Bourque C, Agre P, Ottersen OP (1997) Specialized membrane domains for water transport in glial cells: high-resolution immunogold cytochemistry of aquaporin-4 in rat brain. J Neurosci 17:171\u2013180. https:\/\/doi.org\/10.1523\/JNEUROSCI.17-01-00171.1997","journal-title":"J Neurosci"},{"key":"2725_CR56","doi-asserted-by":"publisher","first-page":"609","DOI":"10.1146\/annurev-immunol-032712-095948","volume":"34","author":"M Panduro","year":"2016","unstructured":"Panduro M, Benoist C, Mathis D (2016) Tissue Tregs. Annu Rev Immunol 34:609\u2013633. https:\/\/doi.org\/10.1146\/annurev-immunol-032712-095948","journal-title":"Annu Rev Immunol"},{"key":"2725_CR57","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1038\/nri.2017.105","volume":"18","author":"V Papayannopoulos","year":"2018","unstructured":"Papayannopoulos V (2018) Neutrophil extracellular traps in immunity and disease. Nat Rev Immunol 18:134\u2013147. https:\/\/doi.org\/10.1038\/nri.2017.105","journal-title":"Nat Rev Immunol"},{"key":"2725_CR58","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1007\/s00401-011-0824-0","volume":"122","author":"M Pohl","year":"2011","unstructured":"Pohl M, Fischer MT, Mader S, Schanda K, Kitic M, Sharma R et al (2011) Pathogenic T cell responses against aquaporin 4. Acta Neuropathol 122:21\u201334. https:\/\/doi.org\/10.1007\/s00401-011-0824-0","journal-title":"Acta Neuropathol"},{"key":"2725_CR59","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1186\/2051-5960-1-85","volume":"1","author":"M Pohl","year":"2013","unstructured":"Pohl M, Kawakami N, Kitic M, Bauer J, Martins R, Fischer MT et al (2013) T cell-activation in neuromyelitis optica lesions plays a role in their formation. Acta Neuropathol Commun 1:85. https:\/\/doi.org\/10.1186\/2051-5960-1-85","journal-title":"Acta Neuropathol Commun"},{"key":"2725_CR60","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20201012","author":"C Radermecker","year":"2020","unstructured":"Radermecker C, Detrembleur N, Guiot J, Cavalier E, Henket M, d\u2019Emal C et al (2020) Neutrophil extracellular traps infiltrate the lung airway, interstitial, and vascular compartments in severe COVID-19. J Exp Med. https:\/\/doi.org\/10.1084\/jem.20201012","journal-title":"J Exp Med"},{"key":"2725_CR61","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1007\/978-1-0716-2364-0_20","volume":"2506","author":"C Radermecker","year":"2022","unstructured":"Radermecker C, Hego A, Vanwinge C, Marichal T (2022) Methods to Detect Neutrophil Extracellular Traps in Asthma. Methods Mol Biol 2506:281\u2013295. https:\/\/doi.org\/10.1007\/978-1-0716-2364-0_20","journal-title":"Methods Mol Biol"},{"key":"2725_CR62","doi-asserted-by":"publisher","first-page":"699","DOI":"10.1007\/s00401-013-1172-z","volume":"126","author":"J Ratelade","year":"2013","unstructured":"Ratelade J, Asavapanumas N, Ritchie AM, Wemlinger S, Bennett JL, Verkman AS (2013) Involvement of antibody-dependent cell-mediated cytotoxicity in inflammatory demyelination in a mouse model of neuromyelitis optica. Acta Neuropathol 126:699\u2013709. https:\/\/doi.org\/10.1007\/s00401-013-1172-z","journal-title":"Acta Neuropathol"},{"key":"2725_CR63","doi-asserted-by":"publisher","first-page":"1194","DOI":"10.1093\/brain\/awl371","volume":"130","author":"SF Roemer","year":"2007","unstructured":"Roemer SF, Parisi JE, Lennon VA, Benarroch EE, Lassmann H, Bruck W et al (2007) Pattern-specific loss of aquaporin-4 immunoreactivity distinguishes neuromyelitis optica from multiple sclerosis. Brain 130:1194\u20131205. https:\/\/doi.org\/10.1093\/brain\/awl371","journal-title":"Brain"},{"key":"2725_CR64","doi-asserted-by":"publisher","first-page":"1044","DOI":"10.1097\/WNR.0b013e32835ab480","volume":"23","author":"S Saadoun","year":"2012","unstructured":"Saadoun S, Bridges LR, Verkman AS, Papadopoulos MC (2012) Paucity of natural killer and cytotoxic T cells in human neuromyelitis optica lesions. NeuroReport 23:1044\u20131047. https:\/\/doi.org\/10.1097\/WNR.0b013e32835ab480","journal-title":"NeuroReport"},{"key":"2725_CR65","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1002\/ana.22686","volume":"71","author":"S Saadoun","year":"2012","unstructured":"Saadoun S, Waters P, MacDonald C, Bell BA, Vincent A, Verkman AS et al (2012) Neutrophil protease inhibition reduces neuromyelitis optica-immunoglobulin G-induced damage in mouse brain. Ann Neurol 71:323\u2013333. https:\/\/doi.org\/10.1002\/ana.22686","journal-title":"Ann Neurol"},{"key":"2725_CR66","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1002\/ana.23721","volume":"73","author":"E Saji","year":"2013","unstructured":"Saji E, Arakawa M, Yanagawa K, Toyoshima Y, Yokoseki A, Okamoto K et al (2013) Cognitive impairment and cortical degeneration in neuromyelitis optica. Ann Neurol 73:65\u201376. https:\/\/doi.org\/10.1002\/ana.23721","journal-title":"Ann Neurol"},{"key":"2725_CR67","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneuroim.2023.578109","volume":"380","author":"K Serizawa","year":"2023","unstructured":"Serizawa K, Miyake S, Katsura Y, Yorozu K, Kurasawa M, Tomizawa-Shinohara H et al (2023) Intradermal AQP4 peptide immunization induces clinical features of neuromyelitis optica spectrum disorder in mice. J Neuroimmunol 380:578109. https:\/\/doi.org\/10.1016\/j.jneuroim.2023.578109","journal-title":"J Neuroimmunol"},{"key":"2725_CR68","doi-asserted-by":"publisher","first-page":"946","DOI":"10.1038\/nm.1999","volume":"15","author":"T Shichita","year":"2009","unstructured":"Shichita T, Sugiyama Y, Ooboshi H, Sugimori H, Nakagawa R, Takada I et al (2009) Pivotal role of cerebral interleukin-17-producing gammadeltaT cells in the delayed phase of ischemic brain injury. Nat Med 15:946\u2013950. https:\/\/doi.org\/10.1038\/nm.1999","journal-title":"Nat Med"},{"key":"2725_CR69","doi-asserted-by":"publisher","first-page":"L342","DOI":"10.1152\/ajplung.00151.2012","volume":"304","author":"JM Tadie","year":"2013","unstructured":"Tadie JM, Bae HB, Jiang S, Park DW, Bell CP, Yang H et al (2013) HMGB1 promotes neutrophil extracellular trap formation through interactions with Toll-like receptor 4. Am J Physiol Lung Cell Mol Physiol 304:L342-349. https:\/\/doi.org\/10.1152\/ajplung.00151.2012","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"key":"2725_CR70","doi-asserted-by":"publisher","first-page":"298","DOI":"10.1016\/S1474-4422(20)30066-1","volume":"19","author":"M Tahara","year":"2020","unstructured":"Tahara M, Oeda T, Okada K, Kiriyama T, Ochi K, Maruyama H et al (2020) Safety and efficacy of rituximab in neuromyelitis optica spectrum disorders (RIN-1 study): a multicentre, randomised, double-blind, placebo-controlled trial. Lancet Neurol 19:298\u2013306. https:\/\/doi.org\/10.1016\/S1474-4422(20)30066-1","journal-title":"Lancet Neurol"},{"key":"2725_CR71","doi-asserted-by":"publisher","first-page":"162","DOI":"10.1016\/s1474-4422(17)30470-2","volume":"17","author":"AJ Thompson","year":"2018","unstructured":"Thompson AJ, Banwell BL, Barkhof F, Carroll WM, Coetzee T, Comi G et al (2018) Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteria. The Lancet Neurology 17:162\u2013173. https:\/\/doi.org\/10.1016\/s1474-4422(17)30470-2","journal-title":"The Lancet Neurology"},{"key":"2725_CR72","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1111\/bpa.12097","volume":"24","author":"A Uzawa","year":"2014","unstructured":"Uzawa A, Masahiro M, Kuwabara S (2014) Cytokines and chemokines in neuromyelitis optica: pathogenetic and therapeutic implications. Brain Pathol 24:67\u201373. https:\/\/doi.org\/10.1111\/bpa.12097","journal-title":"Brain Pathol"},{"key":"2725_CR73","doi-asserted-by":"publisher","first-page":"1443","DOI":"10.1177\/1352458510379247","volume":"16","author":"A Uzawa","year":"2010","unstructured":"Uzawa A, Mori M, Arai K, Sato Y, Hayakawa S, Masuda S et al (2010) Cytokine and chemokine profiles in neuromyelitis optica: significance of interleukin-6. Mult Scler 16:1443\u20131452. https:\/\/doi.org\/10.1177\/1352458510379247","journal-title":"Mult Scler"},{"key":"2725_CR74","doi-asserted-by":"publisher","first-page":"3686","DOI":"10.4049\/jimmunol.1501650","volume":"196","author":"K Van Avondt","year":"2016","unstructured":"Van Avondt K, van der Linden M, Naccache PH, Egan DA, Meyaard L (2016) Signal Inhibitory Receptor on Leukocytes-1 Limits the Formation of Neutrophil Extracellular Traps, but Preserves Intracellular Bacterial Killing. J Immunol 196:3686\u20133694. https:\/\/doi.org\/10.4049\/jimmunol.1501650","journal-title":"J Immunol"},{"key":"2725_CR75","doi-asserted-by":"publisher","first-page":"2047","DOI":"10.1002\/art.41047","volume":"71","author":"LS van Dam","year":"2019","unstructured":"van Dam LS, Kraaij T, Kamerling SWA, Bakker JA, Scherer UH, Rabelink TJ et al (2019) Intrinsically Distinct Role of Neutrophil Extracellular Trap Formation in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis Compared to Systemic Lupus Erythematosus. Arthritis Rheumatol 71:2047\u20132058. https:\/\/doi.org\/10.1002\/art.41047","journal-title":"Arthritis Rheumatol"},{"key":"2725_CR76","doi-asserted-by":"publisher","first-page":"494","DOI":"10.1038\/s41576-023-00580-2","volume":"24","author":"K Vandereyken","year":"2023","unstructured":"Vandereyken K, Sifrim A, Thienpont B, Voet T (2023) Methods and applications for single-cell and spatial multi-omics. Nat Rev Genet 24:494\u2013515. https:\/\/doi.org\/10.1038\/s41576-023-00580-2","journal-title":"Nat Rev Genet"},{"key":"2725_CR77","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1002\/ana.23651","volume":"72","author":"M Varrin-Doyer","year":"2012","unstructured":"Varrin-Doyer M, Spencer CM, Schulze-Topphoff U, Nelson PA, Stroud RM, Cree BA et al (2012) Aquaporin 4-specific T cells in neuromyelitis optica exhibit a Th17 bias and recognize Clostridium ABC transporter. Ann Neurol 72:53\u201364. https:\/\/doi.org\/10.1002\/ana.23651","journal-title":"Ann Neurol"},{"key":"2725_CR78","doi-asserted-by":"publisher","first-page":"5730","DOI":"10.4049\/jimmunol.181.8.5730","volume":"181","author":"T Vincent","year":"2008","unstructured":"Vincent T, Saikali P, Cayrol R, Roth AD, Bar-Or A, Prat A et al (2008) Functional consequences of neuromyelitis optica-IgG astrocyte interactions on blood-brain barrier permeability and granulocyte recruitment. J Immunol 181:5730\u20135737. https:\/\/doi.org\/10.4049\/jimmunol.181.8.5730","journal-title":"J Immunol"},{"key":"2725_CR79","doi-asserted-by":"publisher","first-page":"6058","DOI":"10.1126\/scitranslmed.abl6058","volume":"14","author":"I Vincenti","year":"2022","unstructured":"Vincenti I, Page N, Steinbach K, Yermanos A, Lemeille S, Nunez N et al (2022) Tissue-resident memory CD8(+) T cells cooperate with CD4(+) T cells to drive compartmentalized immunopathology in the CNS. Science translational medicine 14:6058. https:\/\/doi.org\/10.1126\/scitranslmed.abl6058","journal-title":"Science translational medicine"},{"key":"2725_CR80","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1159\/000345994","volume":"20","author":"H Wang","year":"2013","unstructured":"Wang H, Wang K, Wang C, Xu F, Zhong X, Qiu W et al (2013) Cerebrospinal fluid high-mobility group box protein 1 in neuromyelitis optica and multiple sclerosis. NeuroImmunoModulation 20:113\u2013118. https:\/\/doi.org\/10.1159\/000345994","journal-title":"NeuroImmunoModulation"},{"key":"2725_CR81","doi-asserted-by":"publisher","first-page":"1313","DOI":"10.1016\/j.jocn.2011.01.031","volume":"18","author":"HH Wang","year":"2011","unstructured":"Wang HH, Dai YQ, Qiu W, Lu ZQ, Peng FH, Wang YG et al (2011) Interleukin-17-secreting T cells in neuromyelitis optica and multiple sclerosis during relapse. J Clin Neurosci 18:1313\u20131317. https:\/\/doi.org\/10.1016\/j.jocn.2011.01.031","journal-title":"J Clin Neurosci"},{"key":"2725_CR82","doi-asserted-by":"publisher","first-page":"510","DOI":"10.1016\/j.neuroscience.2012.08.041","volume":"226","author":"KC Wang","year":"2012","unstructured":"Wang KC, Tsai CP, Lee CL, Chen SY, Chin LT, Chen SJ (2012) Elevated plasma high-mobility group box 1 protein is a potential marker for neuromyelitis optica. Neuroscience 226:510\u2013516. https:\/\/doi.org\/10.1016\/j.neuroscience.2012.08.041","journal-title":"Neuroscience"},{"key":"2725_CR83","doi-asserted-by":"publisher","first-page":"316","DOI":"10.1126\/science.aaa8064","volume":"349","author":"A Warnatsch","year":"2015","unstructured":"Warnatsch A, Ioannou M, Wang Q, Papayannopoulos V (2015) Inflammation. Neutrophil extracellular traps license macrophages for cytokine production in atherosclerosis. Science 349:316\u2013320. https:\/\/doi.org\/10.1126\/science.aaa8064","journal-title":"Science"},{"key":"2725_CR84","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1212\/WNL.0000000000001729","volume":"85","author":"DM Wingerchuk","year":"2015","unstructured":"Wingerchuk DM, Banwell B, Bennett JL, Cabre P, Carroll W, Chitnis T et al (2015) International consensus diagnostic criteria for neuromyelitis optica spectrum disorders. Neurology 85:177\u2013189. https:\/\/doi.org\/10.1212\/WNL.0000000000001729","journal-title":"Neurology"},{"key":"2725_CR85","doi-asserted-by":"publisher","first-page":"1485","DOI":"10.1212\/01.wnl.0000216139.44259.74","volume":"66","author":"DM Wingerchuk","year":"2006","unstructured":"Wingerchuk DM, Lennon VA, Pittock SJ, Lucchinetti CF, Weinshenker BG (2006) Revised diagnostic criteria for neuromyelitis optica. Neurology 66:1485\u20131489. https:\/\/doi.org\/10.1212\/01.wnl.0000216139.44259.74","journal-title":"Neurology"},{"key":"2725_CR86","doi-asserted-by":"publisher","DOI":"10.1172\/JCI141694","author":"A Winkler","year":"2021","unstructured":"Winkler A, Wrzos C, Haberl M, Weil MT, Gao M, Mobius W et al (2021) Blood-brain barrier resealing in neuromyelitis optica occurs independently of astrocyte regeneration. J Clin Investig. https:\/\/doi.org\/10.1172\/JCI141694","journal-title":"J Clin Investig"},{"key":"2725_CR87","doi-asserted-by":"publisher","first-page":"2114","DOI":"10.1056\/NEJMoa1901747","volume":"381","author":"T Yamamura","year":"2019","unstructured":"Yamamura T, Kleiter I, Fujihara K, Palace J, Greenberg B, Zakrzewska-Pniewska B et al (2019) Trial of Satralizumab in Neuromyelitis Optica Spectrum Disorder. N Engl J Med 381:2114\u20132124. https:\/\/doi.org\/10.1056\/NEJMoa1901747","journal-title":"N Engl J Med"},{"key":"2725_CR88","doi-asserted-by":"publisher","first-page":"1628","DOI":"10.1212\/WNL.0b013e3181c1deb9","volume":"73","author":"K Yanagawa","year":"2009","unstructured":"Yanagawa K, Kawachi I, Toyoshima Y, Yokoseki A, Arakawa M, Hasegawa A et al (2009) Pathologic and immunologic profiles of a limited form of neuromyelitis optica with myelitis. Neurology 73:1628\u20131637. https:\/\/doi.org\/10.1212\/WNL.0b013e3181c1deb9","journal-title":"Neurology"},{"key":"2725_CR89","doi-asserted-by":"publisher","first-page":"1386","DOI":"10.1038\/nm.2847","volume":"18","author":"BG Yipp","year":"2012","unstructured":"Yipp BG, Petri B, Salina D, Jenne CN, Scott BN, Zbytnuik LD et al (2012) Infection-induced NETosis is a dynamic process involving neutrophil multitasking in vivo. Nat Med 18:1386\u20131393. https:\/\/doi.org\/10.1038\/nm.2847","journal-title":"Nat Med"},{"key":"2725_CR90","doi-asserted-by":"publisher","first-page":"520","DOI":"10.1093\/brain\/awt314","volume":"137","author":"A Yokoseki","year":"2014","unstructured":"Yokoseki A, Saji E, Arakawa M, Kosaka T, Hokari M, Toyoshima Y et al (2014) Hypertrophic pachymeningitis: significance of myeloperoxidase anti-neutrophil cytoplasmic antibody. Brain 137:520\u2013536. https:\/\/doi.org\/10.1093\/brain\/awt314","journal-title":"Brain"},{"key":"2725_CR91","doi-asserted-by":"publisher","first-page":"1900","DOI":"10.1093\/brain\/awx113","volume":"140","author":"T Zrzavy","year":"2017","unstructured":"Zrzavy T, Hametner S, Wimmer I, Butovsky O, Weiner HL, Lassmann H (2017) Loss of \u201chomeostatic\u201d microglia and patterns of their activation in active multiple sclerosis. Brain 140:1900\u20131913. https:\/\/doi.org\/10.1093\/brain\/awx113","journal-title":"Brain"},{"key":"2725_CR92","doi-asserted-by":"publisher","first-page":"791","DOI":"10.1111\/bpa.12583","volume":"28","author":"T Zrzavy","year":"2018","unstructured":"Zrzavy T, Machado-Santos J, Christine S, Baumgartner C, Weiner HL, Butovsky O et al (2018) Dominant role of microglial and macrophage innate immune responses in human ischemic infarcts. Brain Pathol 28:791\u2013805. https:\/\/doi.org\/10.1111\/bpa.12583","journal-title":"Brain Pathol"}],"container-title":["Acta Neuropathologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00401-024-02725-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00401-024-02725-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00401-024-02725-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,24]],"date-time":"2024-04-24T14:04:05Z","timestamp":1713967445000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00401-024-02725-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,24]]},"references-count":92,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,6]]}},"alternative-id":["2725"],"URL":"https:\/\/doi.org\/10.1007\/s00401-024-02725-x","relation":{},"ISSN":["0001-6322","1432-0533"],"issn-type":[{"value":"0001-6322","type":"print"},{"value":"1432-0533","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4,24]]},"assertion":[{"value":"13 February 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 March 2024","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 March 2024","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 April 2024","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"AN, FY, ES, HS, YT, KY, MA, MH, AY, TW, KO, H.Takebayashi, CF, KI, YT, SO, MY, H. Takahashi, MN, HI, AK, and OO have no competing interests to disclose. IK reports receiving funding for research, travel, and\/or speaker\u2019s honoraria from Chugai Pharmaceuticals, Novartis Pharma, Biogen, Alexion Pharmaceuticals, Mitsubishi Tanabe Pharma, Takeda Pharmaceutical Company, Teijin Pharma, Argenx, and Daiichi-Sankyo and is a scientific advisory board member for Mitsubishi Tanabe Pharma and Chugai Pharmaceuticals.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}],"article-number":"76"}}