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No research support is received. These companies did not fund and had no role in the conception or performance of this research project. B.S.A. has received research funding from CDC, NIH, CJD Foundation, and Ionis. B.S.A. has provided consultation for Ionis, Gates Biosciences, and Sangamo and received royalties from Wolter\u2013Kluwer. All other authors have no competing interests to declare.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}],"article-number":"10"}}