{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T04:45:14Z","timestamp":1780634714178,"version":"3.54.1"},"reference-count":15,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,8,27]],"date-time":"2024-08-27T00:00:00Z","timestamp":1724716800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,8,27]],"date-time":"2024-08-27T00:00:00Z","timestamp":1724716800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100006431","name":"Canc\u00e9rop\u00f4le Ile de France","doi-asserted-by":"publisher","award":["PJA 2019-1-EMERG-21-ICM-1"],"award-info":[{"award-number":["PJA 2019-1-EMERG-21-ICM-1"]}],"id":[{"id":"10.13039\/501100006431","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Acta Neuropathol"],"DOI":"10.1007\/s00401-024-02791-1","type":"journal-article","created":{"date-parts":[[2024,8,27]],"date-time":"2024-08-27T18:02:42Z","timestamp":1724781762000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Correlation between natural history and multi-omics profiling of meningiomas in NF2-related schwannomatosis suggests role of methylation group and immune microenvironment in tumor growth rate"],"prefix":"10.1007","volume":"148","author":[{"given":"Yu","family":"Teranishi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrey","family":"Yurchenko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suzanne","family":"Tran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philipp","family":"Sievers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatemeh","family":"Rajabi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Singhabahu","family":"Ruchith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samiya","family":"Abi-Jaoude","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antoine","family":"Blouin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franck","family":"Bielle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominique","family":"Cazals-Hatem","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felix","family":"Sahm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergey","family":"Nikolaev","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel","family":"Kalamarides","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8470-9516","authenticated-orcid":false,"given":"Matthieu","family":"Peyre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,8,27]]},"reference":[{"key":"2791_CR1","doi-asserted-by":"publisher","first-page":"1377","DOI":"10.3171\/2020.3.JNS192382","volume":"134","author":"S Abi Jaoude","year":"2020","unstructured":"Abi Jaoude S, Peyre M, Degos V, Goutagny S, Parfait B, Kalamarides M (2020) Validation of a scoring system to evaluate the risk of rapid growth of intracranial meningiomas in neurofibromatosis type 2 patients. J Neurosurg 134:1377\u20131385","journal-title":"J Neurosurg"},{"key":"2791_CR2","doi-asserted-by":"publisher","DOI":"10.1038\/s41525-017-0014-7","author":"WL Bi","year":"2017","unstructured":"Bi WL, Greenwald NF, Abedalthagafi M, Wala J, Gibson WJ et al (2017) Genomic landscape of high-grade meningiomas. Npj Genomic Med. https:\/\/doi.org\/10.1038\/s41525-017-0014-7","journal-title":"Npj Genomic Med"},{"issue":"12","key":"2791_CR3","doi-asserted-by":"publisher","first-page":"3067","DOI":"10.1038\/s41591-023-02586-z","volume":"29","author":"WC Chen","year":"2023","unstructured":"Chen WC, Choudhury A, Youngblood MW, Polley MC, Lucas CG et al (2023) Targeted gene expression profiling predicts meningioma outcomes and radiotherapy responses. Nat Med 29(12):3067\u20133076","journal-title":"Nat Med"},{"key":"2791_CR4","doi-asserted-by":"publisher","first-page":"649","DOI":"10.1038\/s41588-022-01061-8","volume":"54","author":"A Choudhury","year":"2022","unstructured":"Choudhury A, Magill ST, Eaton CD, Prager BC, Chen WC, Cady MA et al (2022) Meningioma DNA methylation groups identify biological drivers and therapeutic vulnerabilities. Nat Genet 54:649\u2013659","journal-title":"Nat Genet"},{"key":"2791_CR5","doi-asserted-by":"publisher","first-page":"1253","DOI":"10.1038\/ng.3651","volume":"48","author":"VE Clark","year":"2016","unstructured":"Clark VE, Harmanc\u0131 AS, Bai H, Youngblood MW, Lee TI, Baranoski JF et al (2016) Recurrent somatic mutations in POLR2A define a distinct subset of meningiomas. Nat Genet 48:1253\u20131259","journal-title":"Nat Genet"},{"key":"2791_CR6","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1186\/s12885-017-3127-6","volume":"17","author":"R Dewan","year":"2017","unstructured":"Dewan R, Pemov A, Dutra AS, Pak ED, Edwards NA, Ray-Chaudhury A et al (2017) First insight into the somatic mutation burden of neurofibromatosis type 2-associated grade I and grade II meningiomas: a case report comprehensive genomic study of two cranial meningiomas with vastly different clinical presentation. BMC Cancer 17:127","journal-title":"BMC Cancer"},{"key":"2791_CR7","doi-asserted-by":"publisher","first-page":"1090","DOI":"10.1093\/neuonc\/nos129","volume":"14","author":"S Goutagny","year":"2012","unstructured":"Goutagny S, Bah AB, Henin D, Parfait B, Grayeli AB et al (2012) Long-term follow-up of 287 meningiomas in neurofibromatosis type 2 patients: clinical, radiological, and molecular features. Neuro-Oncol 14:1090\u20131096","journal-title":"Neuro-Oncol"},{"key":"2791_CR8","doi-asserted-by":"publisher","first-page":"14433","DOI":"10.1038\/ncomms14433","volume":"8","author":"AS Harmanc\u0131","year":"2017","unstructured":"Harmanc\u0131 AS, Youngblood MW, Clark VE, Co\u015fkun S, Henegariu O et al (2017) Integrated genomic analyses of de novo pathways underlying atypical meningiomas. Nat Commun 8:14433","journal-title":"Nat Commun"},{"issue":"7874","key":"2791_CR9","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1038\/s41586-021-03850-3","volume":"597","author":"F Nassiri","year":"2021","unstructured":"Nassiri F, Liu J, Patil V, Mamatjan Y, Wang JZ, Hugh-White R et al (2021) A clinically applicable integrative molecular classification of meningiomas. Nature 597(7874):119\u2013125","journal-title":"Nature"},{"issue":"2","key":"2791_CR10","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1007\/s00401-019-02008-w","volume":"138","author":"N Paramasivam","year":"2019","unstructured":"Paramasivam N, H\u00fcbschmann D, Toprak UH, Ishaque N, Neidert M, Schrimpf D et al (2019) Mutational patterns and regulatory networks in epigenetic subgroups of meningioma. Acta Neuropathol 138(2):295\u2013308","journal-title":"Acta Neuropathol"},{"key":"2791_CR11","doi-asserted-by":"publisher","first-page":"12563","DOI":"10.1038\/s41598-020-69074-z","volume":"10","author":"A Pemov","year":"2020","unstructured":"Pemov A, Dewan R, Hansen NF, Chandrasekharappa SC, Ray-Chaudhury A, Jones K et al (2020) Comparative clinical and genomic analysis of neurofibromatosis type 2-associated cranial and spinal meningiomas. Sci Rep 10:12563","journal-title":"Sci Rep"},{"key":"2791_CR12","doi-asserted-by":"publisher","first-page":"682","DOI":"10.1016\/S1470-2045(17)30155-9","volume":"18","author":"F Sahm","year":"2017","unstructured":"Sahm F, Schrimpf D, Stichel D, Jones DTW, Hielscher T, Schefzyk S et al (2017) DNA methylation-based classification and grading system for meningioma: a multicentre, retrospective analysis. Lancet Oncol 18:682\u2013694","journal-title":"Lancet Oncol"},{"issue":"1","key":"2791_CR13","doi-asserted-by":"publisher","first-page":"156","DOI":"10.1186\/s40478-023-01645-3","volume":"11","author":"Y Teranishi","year":"2023","unstructured":"Teranishi Y, Miyawaki S, Nakatochi M, Okano A, Ohara K, Hongo H et al (2023) Meningiomas in patients with neurofibromatosis type 2 predominantly comprise \u201cimmunogenic subtype\u201d tumours characterised by macrophage infiltration. Acta Neuropathol Commun 11(1):156","journal-title":"Acta Neuropathol Commun"},{"issue":"13","key":"2791_CR14","doi-asserted-by":"publisher","first-page":"3672","DOI":"10.1016\/j.celrep.2018.03.013","volume":"22","author":"HN Vasudevan","year":"2018","unstructured":"Vasudevan HN, Braunstein SE, Phillips JJ, Pekmezci M, Tomlin BA, Wu A et al (2018) Comprehensive molecular profiling identifies FOXM1 as a key transcription factor for meningioma proliferation. Cell Rep 22(13):3672\u20133683","journal-title":"Cell Rep"},{"key":"2791_CR15","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1186\/s13073-022-01051-9","volume":"14","author":"AZ Wang","year":"2022","unstructured":"Wang AZ, Bowman-Kirigin JA, Desai R, Kang LI, Patel PR, Patel B et al (2022) Single-cell profiling of human dura and meningioma reveals cellular meningeal landscape and insights into meningioma immune response. Genome Med 14:49","journal-title":"Genome Med"}],"container-title":["Acta Neuropathologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00401-024-02791-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00401-024-02791-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00401-024-02791-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,27]],"date-time":"2024-08-27T18:04:57Z","timestamp":1724781897000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00401-024-02791-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,27]]},"references-count":15,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["2791"],"URL":"https:\/\/doi.org\/10.1007\/s00401-024-02791-1","relation":{},"ISSN":["1432-0533"],"issn-type":[{"value":"1432-0533","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,8,27]]},"assertion":[{"value":"17 May 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 August 2024","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 August 2024","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 August 2024","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"30"}}