{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T10:32:04Z","timestamp":1788258724835,"version":"build-2803163510"},"reference-count":35,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2017,4,25]],"date-time":"2017-04-25T00:00:00Z","timestamp":1493078400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Arch Orthop Trauma Surg"],"published-print":{"date-parts":[[2017,7]]},"DOI":"10.1007\/s00402-017-2703-1","type":"journal-article","created":{"date-parts":[[2017,4,25]],"date-time":"2017-04-25T15:25:07Z","timestamp":1493133907000},"page":"903-911","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":41,"title":["Effect and safety of early weight-bearing on the outcome after open-wedge high tibial osteotomy: a systematic review and meta-analysis"],"prefix":"10.1007","volume":"137","author":[{"given":"O-Sung","family":"Lee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soyeon","family":"Ahn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong Seuk","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,4,25]]},"reference":[{"key":"2703_CR1","doi-asserted-by":"publisher","unstructured":"Aalderink KJ, Shaffer M, Amendola A (2010) Rehabilitation following high tibial osteotomy. Clin Sports Med 29:291\u2013301, ix. doi: 10.1016\/j.csm.2009.12.005","DOI":"10.1016\/j.csm.2009.12.005"},{"key":"2703_CR2","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1007\/s00167-005-0690-1","volume":"14","author":"JD Agneskirchner","year":"2006","unstructured":"Agneskirchner JD, Freiling D, Hurschler C, Lobenhoffer P (2006) Primary stability of four different implants for opening wedge high tibial osteotomy. Knee Surg Sports Traumatol Arthrosc 14:291\u2013300. doi: 10.1007\/s00167-005-0690-1","journal-title":"Knee Surg Sports Traumatol Arthrosc"},{"key":"2703_CR3","doi-asserted-by":"publisher","first-page":"1548","DOI":"10.1302\/0301-620x.90b12.21198","volume":"90","author":"JM Brinkman","year":"2008","unstructured":"Brinkman JM, Lobenhoffer P, Agneskirchner JD, Staubli AE, Wymenga AB, van Heerwaarden RJ (2008) Osteotomies around the knee: patient selection, stability of fixation and bone healing in high tibial osteotomies. J Bone Joint Surg Br 90:1548\u20131557. doi: 10.1302\/0301-620x.90b12.21198","journal-title":"J Bone Joint Surg Br"},{"key":"2703_CR4","doi-asserted-by":"crossref","first-page":"193","DOI":"10.3109\/17453671003619003","volume":"81","author":"JM Brinkman","year":"2010","unstructured":"Brinkman JM, Luites JWH, Wymenga AB, Van Heerwaarden RJ (2010) Early full weight bearing is safe in open-wedge high tibial osteotomy: RSA analysis of postoperative stability compared to delayed weight bearing. Acta Orthop 81:193\u2013198","journal-title":"Acta Orthop"},{"key":"2703_CR5","doi-asserted-by":"publisher","first-page":"1454","DOI":"10.1302\/0301-620x.88b11.17743","volume":"88","author":"RW Brouwer","year":"2006","unstructured":"Brouwer RW, Bierma-Zeinstra SM, van Raaij TM, Verhaar JA (2006) Osteotomy for medial compartment arthritis of the knee using a closing wedge or an opening wedge controlled by a Puddu plate. A one-year randomised, controlled study. J Bone Joint Surg Br 88:1454\u20131459. doi: 10.1302\/0301-620x.88b11.17743","journal-title":"J Bone Joint Surg Br"},{"key":"2703_CR6","doi-asserted-by":"publisher","first-page":"1425","DOI":"10.2106\/jbjs.m.00786","volume":"96","author":"T Duivenvoorden","year":"2014","unstructured":"Duivenvoorden T, Brouwer RW, Baan A, Bos PK, Reijman M, Bierma-Zeinstra SM, Verhaar JA (2014) Comparison of closing-wedge and opening-wedge high tibial osteotomy for medial compartment osteoarthritis of the knee: a randomized controlled trial with a six-year follow-up. J Bone Joint Surg Am 96:1425\u20131432. doi: 10.2106\/jbjs.m.00786","journal-title":"J Bone Joint Surg Am"},{"key":"2703_CR7","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1097\/JSA.0b013e3181f2f23d","volume":"18","author":"CJ Edson","year":"2010","unstructured":"Edson CJ, Fanelli GC, Beck JD (2010) Postoperative rehabilitation of the posterior cruciate ligament. Sports Med Arthrosc 18:275\u2013279. doi: 10.1097\/JSA.0b013e3181f2f23d","journal-title":"Sports Med Arthrosc"},{"key":"2703_CR8","doi-asserted-by":"publisher","first-page":"162","DOI":"10.1097\/JSA.0b013e31821918b2","volume":"19","author":"CJ Edson","year":"2011","unstructured":"Edson CJ, Fanelli GC, Beck JD (2011) Rehabilitation after multiple-ligament reconstruction of the knee. Sports Med Arthrosc 19:162\u2013166. doi: 10.1097\/JSA.0b013e31821918b2","journal-title":"Sports Med Arthrosc"},{"key":"2703_CR9","first-page":"622","volume":"34","author":"HM El-Azab","year":"2011","unstructured":"El-Azab HM, Morgenstern M, Ahrens P, Schuster T, Imhoff AB, Lorenz SG (2011) Limb alignment after open-wedge high tibial osteotomy and its effect on the clinical outcome. Orthopedics 34:622\u2013628","journal-title":"Orthopedics"},{"key":"2703_CR10","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1007\/s00264-013-2082-3","volume":"38","author":"S Floerkemeier","year":"2014","unstructured":"Floerkemeier S, Staubli AE, Schroeter S, Goldhahn S, Lobenhoffer P (2014) Does obesity and nicotine abuse influence the outcome and complication rate after open-wedge high tibial osteotomy? A retrospective evaluation of five hundred and thirty three patients. Int Orthop 38:55\u201360","journal-title":"Int Orthop"},{"key":"2703_CR11","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1007\/s00264-009-0861-7","volume":"34","author":"RD Gaasbeek","year":"2010","unstructured":"Gaasbeek RD, Nicolaas L, Rijnberg WJ, van Loon CJ, van Kampen A (2010) Correction accuracy and collateral laxity in open versus closed wedge high tibial osteotomy. A 1-year randomised controlled study. Int Orthop 34:201\u2013207. doi: 10.1007\/s00264-009-0861-7","journal-title":"Int Orthop"},{"key":"2703_CR12","doi-asserted-by":"publisher","first-page":"1295","DOI":"10.1007\/s00264-014-2633-2","volume":"39","author":"P Hernigou","year":"2015","unstructured":"Hernigou P, Flouzat Lachaniette C, Delambre J, Guissou I, Dahmani O, Ibrahim Ouali M, Poignard A (2015) Full weight bearing and dynamisation with Limmed(R) locked plate fixation accelerates bone regeneration in the volume of opening wedge high tibial osteotomy. Int Orthop 39:1295\u20131300. doi: 10.1007\/s00264-014-2633-2","journal-title":"Int Orthop"},{"key":"2703_CR13","doi-asserted-by":"publisher","first-page":"2377","DOI":"10.1007\/s00264-013-2066-3","volume":"37","author":"P Hernigou","year":"2013","unstructured":"Hernigou P, Queinnec S, Picard L, Guissou I, Naanaa T, Duffiet P, Julian D, Archer V (2013) Safety of a novel high tibial osteotomy locked plate fixation for immediate full weight-bearing: a case-control study. Int Orthop 37:2377\u20132384. doi: 10.1007\/s00264-013-2066-3","journal-title":"Int Orthop"},{"key":"2703_CR14","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1177\/147323000803600302","volume":"36","author":"P Katonis","year":"2008","unstructured":"Katonis P, Papoutsidakis A, Aligizakis A, Tzanakakis G, Kontakis GM, Papagelopoulos PJ (2008) Mechanoreceptors of the posterior cruciate ligament. J Int Med Res 36:387\u2013393","journal-title":"J Int Med Res"},{"key":"2703_CR15","doi-asserted-by":"publisher","first-page":"553","DOI":"10.1002\/jor.20510","volume":"26","author":"D Kendoff","year":"2008","unstructured":"Kendoff D, Board TN, Citak M, Gardner MJ, Hankemeier S, Ostermeier S, Krettek C, Hufner T (2008) Navigated lower limb axis measurements: influence of mechanical weight-bearing simulation. J Orthop Res 26:553\u2013561. doi: 10.1002\/jor.20510","journal-title":"J Orthop Res"},{"key":"2703_CR16","doi-asserted-by":"publisher","DOI":"10.1007\/s00167-015-3849-4","author":"A Khoshbin","year":"2015","unstructured":"Khoshbin A, Sheth U, Ogilvie-Harris D, Mahomed N, Jenkinson R, Gandhi R, Wasserstein D (2015) The effect of patient, provider and surgical factors on survivorship of high tibial osteotomy to total knee arthroplasty: a population-based study. Knee Surg Sports Traumatol Arthrosc. doi: 10.1007\/s00167-015-3849-4","journal-title":"Knee Surg Sports Traumatol Arthrosc"},{"key":"2703_CR17","doi-asserted-by":"publisher","first-page":"1687","DOI":"10.1007\/s00402-013-1854-y","volume":"133","author":"JG Kim","year":"2013","unstructured":"Kim JG, Lee YS, Yang BS, Oh SJ, Yang SJ (2013) Rehabilitation after posterior cruciate ligament reconstruction: a review of the literature and theoretical support. Arch Orthop Trauma Surg 133:1687\u20131695. doi: 10.1007\/s00402-013-1854-y","journal-title":"Arch Orthop Trauma Surg"},{"key":"2703_CR18","doi-asserted-by":"publisher","DOI":"10.1007\/s00167-016-4225-8","author":"JR Lansdaal","year":"2016","unstructured":"Lansdaal JR, Mouton T, Wascher DC, Demey G, Lustig S, Neyret P, Servien E (2016) Early weight bearing versus delayed weight bearing in medial opening wedge high tibial osteotomy: a randomized controlled trial. Knee Surg Sports Traumatol Arthrosc. doi: 10.1007\/s00167-016-4225-8","journal-title":"Knee Surg Sports Traumatol Arthrosc"},{"key":"2703_CR19","doi-asserted-by":"publisher","first-page":"256","DOI":"10.4055\/cios.2013.5.4.256","volume":"5","author":"YS Lee","year":"2013","unstructured":"Lee YS, Jung YB (2013) Posterior cruciate ligament: focus on conflicting issues. Clin Orthop Surg 5:256\u2013262. doi: 10.4055\/cios.2013.5.4.256","journal-title":"Clin Orthop Surg"},{"key":"2703_CR20","doi-asserted-by":"publisher","first-page":"1528","DOI":"10.1002\/acr.20574","volume":"63","author":"SA Mazzuca","year":"2011","unstructured":"Mazzuca SA, Brandt KD, Lane KA, Chakr R (2011) Malalignment and subchondral bone turnover in contralateral knees of overweight\/obese women with unilateral osteoarthritis: implications for bilateral disease. Arthritis Care Res (Hoboken) 63:1528\u20131534. doi: 10.1002\/acr.20574","journal-title":"Arthritis Care Res (Hoboken)"},{"key":"2703_CR21","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1007\/s00167-010-1335-6","volume":"19","author":"G Meidinger","year":"2011","unstructured":"Meidinger G, Imhoff AB, Paul J, Kirchhoff C, Sauerschnig M, Hinterwimmer S (2011) May smokers and overweight patients be treated with a medial open-wedge HTO? Risk factors for non-union. Knee Surg Sports Traumatol Arthrosc 19:333\u2013339","journal-title":"Knee Surg Sports Traumatol Arthrosc"},{"key":"2703_CR22","doi-asserted-by":"publisher","first-page":"639","DOI":"10.1016\/j.arthro.2008.12.020","volume":"25","author":"BS Miller","year":"2009","unstructured":"Miller BS, Downie B, McDonough EB, Wojtys EM (2009) Complications after medial opening wedge high tibial osteotomy. Arthroscopy 25:639\u2013646. doi: 10.1016\/j.arthro.2008.12.020","journal-title":"Arthroscopy"},{"key":"2703_CR23","doi-asserted-by":"publisher","first-page":"1006","DOI":"10.1016\/j.jclinepi.2009.06.005","volume":"62","author":"D Moher","year":"2009","unstructured":"Moher D, Liberati A, Tetzlaff J, Altman DG (2009) Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. J Clin Epidemiol 62:1006\u20131012. doi: 10.1016\/j.jclinepi.2009.06.005","journal-title":"J Clin Epidemiol"},{"key":"2703_CR24","doi-asserted-by":"publisher","first-page":"1262","DOI":"10.1177\/0363546505286144","volume":"34","author":"FR Noyes","year":"2006","unstructured":"Noyes FR, Mayfield W, Barber-Westin SD, Albright JC, Heckmann TP (2006) Opening wedge high tibial osteotomy: an operative technique and rehabilitation program to decrease complications and promote early union and function. Am J Sports Med 34:1262\u20131273. doi: 10.1177\/0363546505286144","journal-title":"Am J Sports Med"},{"key":"2703_CR25","doi-asserted-by":"publisher","DOI":"10.1007\/s00167-015-3592-x","author":"S Schr\u00f6ter","year":"2015","unstructured":"Schr\u00f6ter S, Ateschrang A, Lowe W, Nakayama H, Stockle U, Ihle C (2015) Early full weight-bearing versus 6-week partial weight-bearing after open wedge high tibial osteotomy leads to earlier improvement of the clinical results: a prospective, randomised evaluation. Knee Surg Sports Traumatol Arthrosc. doi: 10.1007\/s00167-015-3592-x","journal-title":"Knee Surg Sports Traumatol Arthrosc"},{"key":"2703_CR26","doi-asserted-by":"publisher","DOI":"10.1016\/j.arthro.2014.08.028","author":"S Schr\u00f6ter","year":"2015","unstructured":"Schr\u00f6ter S, Freude T, Kopp MM, Konstantinidis L, D\u00f6bele S, St\u00f6ckle U, Heerwaarden R (2015) Smoking and unstable hinge fractures cause delayed gap filling irrespective of early weight bearing after open wedge osteotomy. Arthrosc J Arthrosc Related Surg Off Publ Arthrosc Assoc North Am Int Arthrosc Assoc. doi: 10.1016\/j.arthro.2014.08.028","journal-title":"Arthrosc J Arthrosc Related Surg Off Publ Arthrosc Assoc North Am Int Arthrosc Assoc"},{"key":"2703_CR27","doi-asserted-by":"publisher","first-page":"874","DOI":"10.1007\/s00167-009-1000-0","volume":"18","author":"JA Sim","year":"2010","unstructured":"Sim JA, Kwak JH, Yang SH, Choi ES, Lee BK (2010) Effect of weight-bearing on the alignment after open wedge high tibial osteotomy. Knee Surg Sports Traumatol Arthrosc 18:874\u2013878. doi: 10.1007\/s00167-009-1000-0","journal-title":"Knee Surg Sports Traumatol Arthrosc"},{"key":"2703_CR28","doi-asserted-by":"publisher","first-page":"1245","DOI":"10.1302\/0301-620x.92b9.23660","volume":"92","author":"EK Song","year":"2010","unstructured":"Song EK, Seon JK, Park SJ, Jeong MS (2010) The complications of high tibial osteotomy: closing- versus opening-wedge methods. J Bone Joint Surg Br 92:1245\u20131252. doi: 10.1302\/0301-620x.92b9.23660","journal-title":"J Bone Joint Surg Br"},{"key":"2703_CR29","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.joca.2005.08.013","volume":"14","author":"G Spahn","year":"2006","unstructured":"Spahn G, Kirschbaum S, Kahl E (2006) Factors that influence high tibial osteotomy results in patients with medial gonarthritis: a score to predict the results. Osteoarthritis Cartilage 14:190\u2013195","journal-title":"Osteoarthritis Cartilage"},{"key":"2703_CR30","doi-asserted-by":"publisher","first-page":"1030","DOI":"10.1007\/s00167-008-0609-8","volume":"16","author":"R Takeuchi","year":"2008","unstructured":"Takeuchi R, Aratake M, Bito H, Saito I, Kumagai K, Ishikawa H, Akamatsu Y, Sasaki Y, Saito T (2008) Simultaneous bilateral opening-wedge high tibial osteotomy with early full weight-bearing exercise. Knee Surg Sports Traumatol Arthrosc 16:1030\u20131037. doi: 10.1007\/s00167-008-0609-8","journal-title":"Knee Surg Sports Traumatol Arthrosc"},{"key":"2703_CR31","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1016\/j.arthro.2008.08.015","volume":"25","author":"R Takeuchi","year":"2009","unstructured":"Takeuchi R, Ishikawa H, Aratake M, Bito H, Saito I, Kumagai K, Akamatsu Y, Saito T (2009) Medial opening wedge high tibial osteotomy with early full weight bearing. Arthroscopy 25:46\u201353. doi: 10.1016\/j.arthro.2008.08.015","journal-title":"Arthroscopy"},{"key":"2703_CR32","doi-asserted-by":"crossref","unstructured":"Tj\u00f6rnstrand BA, Egund N, Hagstedt BV (1981) High tibial osteotomy: a seven-year clinical and radiographic follow-up. Clin Orthop Relat Res 124\u2013136","DOI":"10.1097\/00003086-198110000-00017"},{"key":"2703_CR33","doi-asserted-by":"publisher","DOI":"10.1007\/s00167-014-3303-z","author":"N Egmond van","year":"2014","unstructured":"van Egmond N, van Grinsven S, van Loon CJ, Gaasbeek RD, van Kampen A (2014) Better clinical results after closed- compared to open-wedge high tibial osteotomy in patients with medial knee osteoarthritis and varus leg alignment. Knee Surg Sports Traumatol Arthrosc. doi: 10.1007\/s00167-014-3303-z","journal-title":"Knee Surg Sports Traumatol Arthrosc"},{"key":"2703_CR34","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1007\/s11999-013-3383-y","volume":"472","author":"AH Houten van","year":"2014","unstructured":"van Houten AH, Heesterbeek PJ, van Heerwaarden RJ, van Tienen TG, Wymenga AB (2014) Medial open wedge high tibial osteotomy: can delayed or nonunion be predicted? Clin Orthop Relat Res 472:1217\u20131223","journal-title":"Clin Orthop Relat Res"},{"key":"2703_CR35","doi-asserted-by":"publisher","first-page":"276","DOI":"10.1016\/j.knee.2015.09.018","volume":"23","author":"T Woodacre","year":"2016","unstructured":"Woodacre T, Ricketts M, Evans JT, Pavlou G, Schranz P, Hockings M, Toms A (2016) Complications associated with opening wedge high tibial osteotomy\u2013A review of the literature and of 15\u00a0years of experience. Knee 23:276\u2013282. doi: 10.1016\/j.knee.2015.09.018","journal-title":"Knee"}],"container-title":["Archives of Orthopaedic and Trauma Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00402-017-2703-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00402-017-2703-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00402-017-2703-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,27]],"date-time":"2022-07-27T22:05:19Z","timestamp":1658959519000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00402-017-2703-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,4,25]]},"references-count":35,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2017,7]]}},"alternative-id":["2703"],"URL":"https:\/\/doi.org\/10.1007\/s00402-017-2703-1","relation":{},"ISSN":["0936-8051","1434-3916"],"issn-type":[{"value":"0936-8051","type":"print"},{"value":"1434-3916","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,4,25]]}}}