{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T14:23:52Z","timestamp":1793283832982,"version":"4.5.0"},"reference-count":19,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2018,7,23]],"date-time":"2018-07-23T00:00:00Z","timestamp":1532304000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Arch Orthop Trauma Surg"],"published-print":{"date-parts":[[2019,1]]},"DOI":"10.1007\/s00402-018-3006-x","type":"journal-article","created":{"date-parts":[[2018,7,23]],"date-time":"2018-07-23T11:19:31Z","timestamp":1532344771000},"page":"73-78","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":44,"title":["Biomechanical and microbiological effects of local vancomycin in anterior cruciate ligament (ACL) reconstruction: a porcine tendon model"],"prefix":"10.1007","volume":"139","author":[{"given":"Karl-Friedrich","family":"Sch\u00fcttler","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Scharm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Stein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas J.","family":"Heyse","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Lohoff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Sommer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anja","family":"Spiess-Naumann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Turgay","family":"Efe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,7,23]]},"reference":[{"key":"3006_CR1","doi-asserted-by":"publisher","first-page":"2844","DOI":"10.1007\/s00167-012-2264-3","volume":"21","author":"R Torres-Claramunt","year":"2013","unstructured":"Torres-Claramunt R, Pelfort X, Erquicia J, Gil-Gonzalez S, Gelber PE, Puig L, Monllau JC (2013) Knee joint infection after ACL reconstruction: prevalence, management and functional outcomes. Knee Surg Sports Traumatol Arthrosc 21:2844\u20132849","journal-title":"Knee Surg Sports Traumatol Arthrosc"},{"key":"3006_CR2","doi-asserted-by":"publisher","first-page":"1392","DOI":"10.1016\/j.arthro.2014.12.026","volume":"31","author":"EC Makhni","year":"2015","unstructured":"Makhni EC, Steinhaus ME, Mehran N, Schulz BS, Ahmad CS (2015) Functional outcome and graft retention in patients with septic arthritis after anterior cruciate ligament reconstruction: a systematic review. Arthroscopy 31:1392\u20131401","journal-title":"Arthroscopy"},{"key":"3006_CR3","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1016\/j.arthro.2011.08.301","volume":"28","author":"CJ Vertullo","year":"2012","unstructured":"Vertullo CJ, Quick M, Jones A, Grayson JE (2012) A surgical technique using presoaked vancomycin hamstring grafts to decrease the risk of infection after anterior cruciate ligament reconstruction. Arthroscopy 28:337\u2013342","journal-title":"Arthroscopy"},{"key":"3006_CR4","doi-asserted-by":"publisher","first-page":"717","DOI":"10.1016\/j.knee.2014.01.007","volume":"21","author":"R Calvo","year":"2014","unstructured":"Calvo R, Figueroa D, Anastasiadis Z, Vaisman A, Olid A, Gili F, Valderrama JJ, De La Fuente P (2014) Septic arthritis in ACL reconstruction surgery with hamstring autografts. Eleven years of experience. Knee 21:717\u2013720","journal-title":"Knee"},{"key":"3006_CR5","doi-asserted-by":"publisher","first-page":"989","DOI":"10.1007\/s00402-017-2704-0","volume":"137","author":"C Domnick","year":"2017","unstructured":"Domnick C, Garcia P, Raschke MJ, Glasbrenner J, Lodde G, Fink C, Herbort M (2017) Trends and incidences of ligament-surgeries and osteotomies of the knee: an analysis of German inpatient records 2005\u20132013. Arch Orthop Trauma Surg 137:989\u2013995","journal-title":"Arch Orthop Trauma Surg"},{"key":"3006_CR6","doi-asserted-by":"publisher","first-page":"593","DOI":"10.1007\/s00402-016-2426-8","volume":"136","author":"S Shafizadeh","year":"2016","unstructured":"Shafizadeh S, Jaecker V, Otchwemah R, Banerjee M, Naendrup JH (2016) Current status of ACL reconstruction in Germany. Arch Orthop Trauma Surg 136:593\u2013603","journal-title":"Arch Orthop Trauma Surg"},{"key":"3006_CR7","doi-asserted-by":"publisher","first-page":"747","DOI":"10.1016\/j.arthro.2014.02.015","volume":"30","author":"M Saper","year":"2014","unstructured":"Saper M, Stephenson K, Heisey M (2014) Arthroscopic irrigation and debridement in the treatment of septic arthritis after anterior cruciate ligament reconstruction. Arthroscopy 30:747\u2013754","journal-title":"Arthroscopy"},{"key":"3006_CR8","doi-asserted-by":"publisher","first-page":"562","DOI":"10.1177\/03635465990270050301","volume":"27","author":"DR McAllister","year":"1999","unstructured":"McAllister DR, Parker RD, Cooper AE, Recht MP, Abate J (1999) Outcomes of postoperative septic arthritis after anterior cruciate ligament reconstruction. Am J Sports Med 27:562\u2013570","journal-title":"Am J Sports Med"},{"key":"3006_CR9","doi-asserted-by":"publisher","first-page":"127","DOI":"10.3113\/JSOA.2013.0127","volume":"22","author":"WF Scully","year":"2013","unstructured":"Scully WF, Fisher SG, Parada SA, Arrington ED (2013) Septic arthritis following anterior cruciate ligament reconstruction: a comprehensive review of the literature. J Surg Orthop Adv 22:127\u2013133","journal-title":"J Surg Orthop Adv"},{"key":"3006_CR10","doi-asserted-by":"publisher","first-page":"2729","DOI":"10.1007\/s00167-015-3558-z","volume":"24","author":"M Phegan","year":"2016","unstructured":"Phegan M, Grayson JE, Vertullo CJ (2016) No infections in 1300 anterior cruciate ligament reconstructions with vancomycin pre-soaking of hamstring grafts. Knee Surg Sports Traumatol Arthrosc 24:2729\u20132735","journal-title":"Knee Surg Sports Traumatol Arthrosc"},{"key":"3006_CR11","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1007\/s00402-013-1910-7","volume":"134","author":"H Yazdi","year":"2014","unstructured":"Yazdi H, Moradi A, Herbort M (2014) The effect of gentamicin in irrigating solutions on articular infection prophylaxis during arthroscopic ACL reconstruction. Arch Orthop Trauma Surg 134:257\u2013261","journal-title":"Arch Orthop Trauma Surg"},{"key":"3006_CR12","doi-asserted-by":"publisher","first-page":"1780","DOI":"10.1177\/0363546513490665","volume":"41","author":"GB Maletis","year":"2013","unstructured":"Maletis GB, Inacio MC, Reynolds S, Desmond JL, Maletis MM, Funahashi TT (2013) Incidence of postoperative anterior cruciate ligament reconstruction infections: graft choice makes a difference. Am J Sports Med 41:1780\u20131785","journal-title":"Am J Sports Med"},{"key":"3006_CR13","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1177\/0363546509346414","volume":"38","author":"JU Barker","year":"2010","unstructured":"Barker JU, Drakos MC, Maak TG, Warren RF, Williams RJ III, Allen AA (2010) Effect of graft selection on the incidence of postoperative infection in anterior cruciate ligament reconstruction. Am J Sports Med 38:281\u2013286","journal-title":"Am J Sports Med"},{"key":"3006_CR14","doi-asserted-by":"publisher","first-page":"1465","DOI":"10.1007\/s00402-016-2529-2","volume":"136","author":"C Domnick","year":"2016","unstructured":"Domnick C, Wieskotter B, Raschke MJ, Schulze M, Kronenberg D, Wefelmeier M, Langer MF, Herbort M (2016) Evaluation of biomechanical properties: are porcine flexor tendons and bovine extensor tendons eligible surrogates for human tendons in in vitro studies? Arch Orthop Trauma Surg 136:1465\u20131471","journal-title":"Arch Orthop Trauma Surg"},{"key":"3006_CR15","doi-asserted-by":"publisher","first-page":"2948","DOI":"10.1007\/s11999-011-1768-3","volume":"469","author":"JE Grayson","year":"2011","unstructured":"Grayson JE, Grant GD, Dukie S, Vertullo CJ (2011) The in vitro elution characteristics of vancomycin from tendons. Clin Orthop Relat Res 469:2948\u20132952","journal-title":"Clin Orthop Relat Res"},{"key":"3006_CR16","doi-asserted-by":"publisher","first-page":"2721","DOI":"10.1007\/s00167-016-4283-y","volume":"24","author":"K Eriksson","year":"2016","unstructured":"Eriksson K, Karlsson J (2016) Local vancomycin in ACL reconstruction: a modern rationale (2016) for morbidity prevention and patient safety. Knee Surg Sports Traumatol Arthrosc 24:2721\u20132723","journal-title":"Knee Surg Sports Traumatol Arthrosc"},{"key":"3006_CR17","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1016\/j.jiph.2015.10.004","volume":"9","author":"M Dogan","year":"2016","unstructured":"Dogan M, Isyar M, Yilmaz I, Bilir B, Sirin DY, Cakmak S, Mahirogullari M (2016) Are the leading drugs against Staphylococcus aureus really toxic to cartilage? J Infect Public Health 9:251\u2013258","journal-title":"J Infect Public Health"},{"key":"3006_CR18","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1097\/00003086-199612000-00027","volume":"333","author":"ML Edin","year":"1996","unstructured":"Edin ML, Miclau T, Lester GE, Lindsey RW, Dahners LE (1996) Effect of cefazolin and vancomycin on osteoblasts in vitro. Clin Orthop Relat Res 333:245\u2013251","journal-title":"Clin Orthop Relat Res"},{"key":"3006_CR19","doi-asserted-by":"publisher","first-page":"200","DOI":"10.1097\/BLO.0b013e31811ff866","volume":"462","author":"V Antoci Jr","year":"2007","unstructured":"Antoci V Jr, Adams CS, Hickok NJ, Shapiro IM, Parvizi J (2007) Antibiotics for local delivery systems cause skeletal cell toxicity in vitro. Clin Orthop Relat Res 462:200\u2013206","journal-title":"Clin Orthop Relat Res"}],"container-title":["Archives of Orthopaedic and Trauma Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00402-018-3006-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00402-018-3006-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00402-018-3006-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,28]],"date-time":"2019-08-28T01:09:59Z","timestamp":1566954599000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00402-018-3006-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7,23]]},"references-count":19,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,1]]}},"alternative-id":["3006"],"URL":"https:\/\/doi.org\/10.1007\/s00402-018-3006-x","relation":{},"ISSN":["0936-8051","1434-3916"],"issn-type":[{"value":"0936-8051","type":"print"},{"value":"1434-3916","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,7,23]]},"assertion":[{"value":"22 May 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 July 2018","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This article does not contain any studies with human participants or animals performed by any of the authors.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}