{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T19:18:16Z","timestamp":1792783096288,"version":"4.5.0"},"reference-count":48,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2020,10,31]],"date-time":"2020-10-31T00:00:00Z","timestamp":1604102400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2020,10,31]],"date-time":"2020-10-31T00:00:00Z","timestamp":1604102400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"VieCuri Medisch Centrum","id":[{"id":"https:\/\/ror.org\/02kjpb485","id-type":"ROR","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001835","name":"Maastricht University","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100001835","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Arch Orthop Trauma Surg"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>The aim of this study was to investigate the associations of patient characteristics, bone mineral density (BMD), bone microarchitecture and calculated bone strength with secondary displacement of a DRF based on radiographic alignment parameters.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and methods<\/jats:title>\n                    <jats:p>Dorsal angulation, radial inclination and ulnar variance were assessed on conventional radiographs of a cohort of 251 patients, 38 men and 213 women, to determine the anatomic position of the DRF at presentation (primary position) and during follow-up.<\/jats:p>\n                    <jats:p>\n                      Secondary fracture displacement was assessed in the non-operatively treated patients (\n                      <jats:italic>N<\/jats:italic>\n                      \u2009=\u2009154) with an acceptable position, preceded (\n                      <jats:italic>N<\/jats:italic>\n                      \u2009=\u200997) or not preceded (\n                      <jats:italic>N<\/jats:italic>\n                      \u2009=\u200957) by primary reduction (baseline position). Additionally, bone microarchitecture and calculated bone strength at the contralateral distal radius and tibia were assessed by HR-pQCT in a subset of, respectively, 63 and 71 patients.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Outcome<\/jats:title>\n                    <jats:p>\n                      Characteristics of patients with and without secondary fracture displacement did not differ. In the model with adjustment for primary reduction [OR 22.00 (2.27\u2013212.86),\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.008], total [OR 0.16 (95% CI 0.04\u20130.68),\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.013] and cortical [OR 0.19 (95% CI 0.05\u20130.80],\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.024] volumetric BMD (vBMD) and cortical thickness [OR 0.13 (95% CI 0.02\u20130.74),\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.021] at the distal radius were associated with secondary DRF displacement. No associations were found for other patient characteristics, such as age gender, BMD or prevalent vertebral fractures.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In conclusion, our study indicates that besides primary reduction, cortical bone quality may be important for the risk of secondary displacement of DRFs.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00402-020-03658-2","type":"journal-article","created":{"date-parts":[[2020,10,31]],"date-time":"2020-10-31T07:04:49Z","timestamp":1604127889000},"page":"1909-1918","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Association of secondary displacement of distal radius fractures with cortical bone quality at the distal radius"],"prefix":"10.1007","volume":"141","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3228-0954","authenticated-orcid":false,"given":"A. 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