{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T23:18:20Z","timestamp":1780528700402,"version":"3.54.1"},"reference-count":23,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2021,5,22]],"date-time":"2021-05-22T00:00:00Z","timestamp":1621641600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2021,5,22]],"date-time":"2021-05-22T00:00:00Z","timestamp":1621641600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Arch Orthop Trauma Surg"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Purpose<\/jats:title>\n                <jats:p>To compare the efficacy of single anterior and single posterior approach of debridement, interbody fusion, and fixation for the treatment of mono-segment lumbar spine tuberculosis (TB) patients.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Eighty-seven patients with mono-segment lumbar TB who underwent debridement, interbody fusion, and fixation through either single anterior (Group A) or single posterior approach (Group B) from January 2007 to January 2017 were enrolled in this study. The duration of the operation, blood loss, complication rate, visual analog scale (VAS), Oswestry disability index (ODI), Frankel scale, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), kyphosis angle, correction rate, correction loss, and time taken for bone graft fusion were compared between the groups.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>The average period of follow-up was 34.3\u2009\u00b1\u20099.5\u00a0months (24\u201356\u00a0months). No significant differences were observed between patients in Group A and patients in Group B in terms of gender, age, body mass index (BMI), duration of illness and preoperative evaluative indices (<jats:italic>P<\/jats:italic>\u2009&gt;\u20090.05). The mean operation time and blood loss was significantly higher in Group A (<jats:italic>P<\/jats:italic>\u2009=\u20090.000), along with a slightly higher rate of complications compared with Group B (<jats:italic>P<\/jats:italic>\u2009=\u20090.848). The VAS, ODI and Frankel scale scores showed significant improvement in both groups (<jats:italic>P<\/jats:italic>\u2009=\u20090.000), along with the ESR, CRP and kyphosis indices (<jats:italic>P<\/jats:italic>\u2009=\u20090.000), which were similar in both groups at the final follow-up.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Both single anterior and single posterior approaches of debridement, interbody fusion and fixation are effective for mono-segment lumbar TB patients, although the single posterior approach is of a shorter duration and results in less blood loss.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00402-021-03955-4","type":"journal-article","created":{"date-parts":[[2021,5,22]],"date-time":"2021-05-22T10:02:47Z","timestamp":1621677767000},"page":"3643-3649","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Comparison between single anterior and single posterior approaches of debridement interbody fusion and fixation for the treatment of mono-segment lumbar spine tuberculosis"],"prefix":"10.1007","volume":"142","author":[{"given":"Hangli","family":"Wu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaqing","family":"Cui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liqun","family":"Gong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yayi","family":"Fan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongchun","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiwei","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,5,22]]},"reference":[{"issue":"10","key":"3955_CR1","doi-asserted-by":"publisher","first-page":"2152","DOI":"10.1017\/S0950268817000863","volume":"145","author":"M Peghin","year":"2017","unstructured":"Peghin M, Rodriguez-Pardo D, Sanchez-Montalva A, Pellis\u00e9 F, Rivas A, Tortola T, Aguilar J, Almirante B, Pigrau C (2017) The changing epidemiology of spinal tuberculosis: the influence of international immigration in Catalonia, 1993\u20132014. Epidemiol Infect 145(10):2152\u20132160. https:\/\/doi.org\/10.1017\/S0950268817000863","journal-title":"Epidemiol Infect"},{"issue":"4","key":"3955_CR2","doi-asserted-by":"publisher","first-page":"507","DOI":"10.3171\/2016.9.SPINE16174","volume":"26","author":"RR De la Garza","year":"2016","unstructured":"De la Garza RR, Goodwin CR, Abu-Bonsrah N, Bydon A, Witham TF, Wolinsky JP, Sciubba DM (2016) The epidemiology of spinal tuberculosis in the United States: an analysis of 2002\u20132011 data. J Neurosurg Spine 26(4):507\u2013512. https:\/\/doi.org\/10.3171\/2016.9.SPINE16174","journal-title":"J Neurosurg Spine"},{"issue":"Suppl 4","key":"3955_CR3","doi-asserted-by":"publisher","first-page":"594","DOI":"10.1007\/s00586-012-2332-x","volume":"22","author":"WY Cheung","year":"2013","unstructured":"Cheung WY, Luk KDK (2013) Clinical and radiological outcomes after conservative treatment of TB spondylitis: is the 15 years\u2019 follow-up in the MRC study long enough? Eur Spine J 22(Suppl 4):594\u2013602. https:\/\/doi.org\/10.1007\/s00586-012-2332-x","journal-title":"Eur Spine J"},{"issue":"9","key":"3955_CR4","doi-asserted-by":"publisher","first-page":"1314","DOI":"10.1016\/S0901-5027(89)80102-X","volume":"71","author":"S Rajasekaran","year":"1989","unstructured":"Rajasekaran S, Soundarapandian S (1989) Progression of kyphosis in tuberculosis of the spine treated by anterior arthrodesis. J Bone Jt Surg Am 71(9):1314\u20131323. https:\/\/doi.org\/10.1016\/S0901-5027(89)80102-X","journal-title":"J Bone Jt Surg Am"},{"issue":"11","key":"3955_CR5","doi-asserted-by":"publisher","first-page":"1858","DOI":"10.1016\/j.spinee.2019.05.002","volume":"19","author":"K Khanna","year":"2019","unstructured":"Khanna K, Sabharwal S (2019) Spinal tuberculosis: a comprehensive review for the modern spine surgeon. Spine J 19(11):1858\u20131870. https:\/\/doi.org\/10.1016\/j.spinee.2019.05.002","journal-title":"Spine J"},{"issue":"185","key":"3955_CR6","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1002\/bjs.18004418508","volume":"44","author":"AR Hodgson","year":"1956","unstructured":"Hodgson AR, Stock FE (1956) Anterior spinal fusion a preliminary communication on the radical treatment of Pott\u2019s disease and Pott\u2019s paraplegia. Br J Surg 44(185):266\u2013275. https:\/\/doi.org\/10.1002\/bjs.18004418508","journal-title":"Br J Surg"},{"issue":"2","key":"3955_CR7","doi-asserted-by":"publisher","first-page":"154","DOI":"10.1016\/j.spinee.2013.11.014","volume":"16","author":"CK Luo","year":"2016","unstructured":"Luo CK, Wang XY, Wu P, Ge L, Zhang HQ, Hu JZ (2016) Single-stage transpedicular decompression, debridement, posterior instrumentation and fusion for thoracic tuberculosis with kyphosis and spinal cord compression in aged. Spine J 16(2):154\u2013162. https:\/\/doi.org\/10.1016\/j.spinee.2013.11.014","journal-title":"Spine J"},{"issue":"1","key":"3955_CR8","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1016\/0020-1383(81)90178-9","volume":"5","author":"T Moula","year":"1981","unstructured":"Moula T, Fowles JV, Kassab MT, Sliman N (1981) Pott\u2019s paraplegia: a clinical review of operative and conservative treatment in 63 adults and children. Int Orthop 5(1):23\u201329. https:\/\/doi.org\/10.1016\/0020-1383(81)90178-9","journal-title":"Int Orthop"},{"issue":"12","key":"3955_CR9","doi-asserted-by":"publisher","first-page":"3862","DOI":"10.1007\/s00586-016-4546-9","volume":"25","author":"PL Yang","year":"2016","unstructured":"Yang PL, Zang QJ, Jian K, Li HP, He XJ (2016) Comparison of clinical efficacy and safety among three surgical approaches for the treatment of spinal tuberculosis: a Meta-analysis. Eur Spine J 25(12):3862\u20133874. https:\/\/doi.org\/10.1007\/s00586-016-4546-9","journal-title":"Eur Spine J"},{"issue":"13","key":"3955_CR10","doi-asserted-by":"publisher","first-page":"1890","DOI":"10.1097\/00007632-199310000-00028","volume":"18","author":"M Oga","year":"1993","unstructured":"Oga M, Arizono T, Takasita M, Sugioka Y (1993) Evaluation of the risk of instrumentation as a foreign body in spinal tuberculosis. Clinical and biologic study. Spine (Phila Pa 1976) 18(13):1890\u20131894. https:\/\/doi.org\/10.1097\/00007632-199310000-00028","journal-title":"Spine (Phila Pa 1976)"},{"issue":"2","key":"3955_CR11","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1097\/BRS.0b013e3181cb46ba","volume":"36","author":"WH Chen","year":"2011","unstructured":"Chen WH, Jiang LS, Dai LY (2011) Influence of bacteria on spinal implant-centered infection: an in vitro and in vivo experimental comparison between Staphylococcus aureus and mycobacterium tuberculosis. Spine (Phila Pa 1976) 36(2):103\u2013108. https:\/\/doi.org\/10.1097\/BRS.0b013e3181cb46ba","journal-title":"Spine (Phila Pa 1976)"},{"issue":"20","key":"3955_CR12","doi-asserted-by":"publisher","first-page":"2342","DOI":"10.1097\/01.brs.0000182109.36973.93","volume":"30","author":"LY Dai","year":"2005","unstructured":"Dai LY, Jiang LS, Wang W, Cui YM (2005) Single-stage anterior autogenous bone grafting and instrumentation in the surgical management of spinal tuberculosis. Spine (Phila Pa 1976) 30(20):2342\u20132349. https:\/\/doi.org\/10.1097\/01.brs.0000182109.36973.93","journal-title":"Spine (Phila Pa 1976)"},{"issue":"8","key":"3955_CR13","first-page":"500","volume":"19","author":"Obaid-ur-Rahman","year":"2009","unstructured":"Obaid-ur-Rahman, Ahmad S, Hussain T (2009) Anterior surgical interventions in spinal tuberculosis. J Coll Physicians Surg Pak 19(8):500\u2013505","journal-title":"J Coll Physicians Surg Pak"},{"issue":"4","key":"3955_CR14","doi-asserted-by":"publisher","first-page":"830","DOI":"10.1007\/s00586-013-3051-7","volume":"23","author":"X Wang","year":"2014","unstructured":"Wang X, Pang X, Wu P, Luo C, Shen X (2014) One-stage anterior debridement, bone grafting and posterior instrumentation vs. single posterior debridement, bone grafting, and instrumentation for the treatment of thoracic and lumbar spinal tuberculosis. Eur Spine J 23(4):830\u2013837. https:\/\/doi.org\/10.1007\/s00586-013-3051-7","journal-title":"Eur Spine J"},{"issue":"2","key":"3955_CR15","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1007\/s00402-010-1138-8","volume":"131","author":"K Gong","year":"2011","unstructured":"Gong K, Wang Z, Luo Z (2011) Single-stage posterior debridement and transforaminal lumbar interbody fusion with autogenous bone grafting and posterior instrumentation in the surgical management of lumbar tuberculosis. Arch Orthop Trauma Surg 131(2):217\u2013223. https:\/\/doi.org\/10.1007\/s00402-010-1138-8","journal-title":"Arch Orthop Trauma Surg"},{"issue":"02","key":"3955_CR16","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1159\/000069113","volume":"12","author":"AM Mukhtar","year":"2003","unstructured":"Mukhtar AM, Farghaly MM, Ahmed SH (2003) Surgical treatment of thoracic and lumbar tuberculosis by anterior interbody fusion and posterior instrumentation. Med Princ Pract 12(02):92\u201396. https:\/\/doi.org\/10.1159\/000069113","journal-title":"Med Princ Pract"},{"issue":"8","key":"3955_CR17","doi-asserted-by":"publisher","first-page":"554","DOI":"10.1097\/01.bsd.0000211202.93125.c7","volume":"19","author":"U Talu","year":"2006","unstructured":"Talu U, Gogus A, Ozturk C, Hamzaoglu A, Domanic U (2006) The role of posterior instrumentation and fusion after anterior radical debridement and fusion in the surgical treatment of spinal tuberculosis: experience of 127 cases. J Spinal Disord Tech 19(8):554\u2013559. https:\/\/doi.org\/10.1097\/01.bsd.0000211202.93125.c7","journal-title":"J Spinal Disord Tech"},{"issue":"1","key":"3955_CR18","doi-asserted-by":"publisher","first-page":"312","DOI":"10.1186\/s13018-018-1021-9","volume":"13","author":"HP Yin","year":"2018","unstructured":"Yin HP, Wang K, Gao Y, Zhang YK, Liu W, Yu S, Li S, Yang SH, Shao ZW, Yang C (2018) Surgical approach and management outcomes for junction tuberculous spondylitis: a retrospective study of 77 patients. J Orthop Surg Res 13(1):312. https:\/\/doi.org\/10.1186\/s13018-018-1021-9","journal-title":"J Orthop Surg Res"},{"issue":"1","key":"3955_CR19","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1186\/s12893-018-0405-4","volume":"18","author":"Y Zhou","year":"2018","unstructured":"Zhou Y, Li W, Liu J, Gong L, Luo J (2018) Comparison of single posterior debridement, bone grafting and instrumentation with single-stage anterior debridement, bone grafting and posterior instrumentation in the treatment of thoracic and thoracolumbar spinal tuberculosis. BMC Surg 18(1):71. https:\/\/doi.org\/10.1186\/s12893-018-0405-4","journal-title":"BMC Surg"},{"key":"3955_CR20","doi-asserted-by":"publisher","first-page":"615","DOI":"10.1186\/s40064-016-2243-0","volume":"5","author":"B Yu","year":"2016","unstructured":"Yu B, He Y (2016) Surgical treatment for lumbar tuberculosis by posterior transforaminal lumbar debridement, interbody fusion, and instrumentation in the aged. Springerplus 5:615. https:\/\/doi.org\/10.1186\/s40064-016-2243-0","journal-title":"Springerplus"},{"issue":"7","key":"3955_CR21","doi-asserted-by":"publisher","first-page":"1311","DOI":"10.1016\/j.injury.2015.03.023","volume":"46","author":"Z Xu","year":"2015","unstructured":"Xu Z, Wang X, Wu P, Pang X, Luo C, Zhang P, Zeng H, Peng W (2015) Surgical treatment for mono-segmental lumbar tuberculosis by single-stage posterior debridement, compact bone grafting and posterior single-segment fixation. Injury 46(7):1311\u20131316. https:\/\/doi.org\/10.1016\/j.injury.2015.03.023","journal-title":"Injury"},{"issue":"45","key":"3955_CR22","doi-asserted-by":"publisher","first-page":"e8574","DOI":"10.1097\/MD.0000000000008574","volume":"96","author":"QH Zhang","year":"2017","unstructured":"Zhang QH, Guo Q, Guo C, Wu J, Liu J, Gao Q, Wang Y (2017) A medium-term follow-up of adult lumbar tuberculosis treating with 3 surgical approaches. Medicine (Baltimore) 96(45):e8574. https:\/\/doi.org\/10.1097\/MD.0000000000008574","journal-title":"Medicine (Baltimore)"},{"issue":"4","key":"3955_CR23","doi-asserted-by":"publisher","first-page":"1056","DOI":"10.1007\/s00586-016-4451-2","volume":"25","author":"K Hassan","year":"2016","unstructured":"Hassan K, Elmorshidy E (2016) Anterior versus posterior approach in surgical treatment of tuberculous spondylodiscitis of thoracic and lumbar spine. Eur Spine J 25(4):1056\u20131063. https:\/\/doi.org\/10.1007\/s00586-016-4451-2","journal-title":"Eur Spine J"}],"container-title":["Archives of Orthopaedic and Trauma Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00402-021-03955-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00402-021-03955-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00402-021-03955-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,10,25]],"date-time":"2022-10-25T13:18:36Z","timestamp":1666703916000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00402-021-03955-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5,22]]},"references-count":23,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2022,12]]}},"alternative-id":["3955"],"URL":"https:\/\/doi.org\/10.1007\/s00402-021-03955-4","relation":{},"ISSN":["1434-3916"],"issn-type":[{"value":"1434-3916","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,5,22]]},"assertion":[{"value":"17 August 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 May 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 May 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Ethical approval from the Ethics Committee of Shaanxi Provincial People\u2019s Hospital was obtained for this study. Each author certifies that all investigations were conducted in conformity with ethical principles.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"All patients signed informed consent forms to publish their personal details in this article.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}}]}}