{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T16:14:10Z","timestamp":1791821650387,"version":"4.3.4"},"reference-count":49,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2022,1,31]],"date-time":"2022-01-31T00:00:00Z","timestamp":1643587200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2022,1,31]],"date-time":"2022-01-31T00:00:00Z","timestamp":1643587200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Arch Orthop Trauma Surg"],"DOI":"10.1007\/s00402-021-04309-w","type":"journal-article","created":{"date-parts":[[2022,1,30]],"date-time":"2022-01-30T19:04:06Z","timestamp":1643569446000},"page":"1441-1449","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":43,"title":["Complete blood platelet and lymphocyte ratios increase diagnostic accuracy of periprosthetic joint infection following total hip arthroplasty"],"prefix":"10.1007","volume":"143","author":[{"given":"Christian","family":"Klemt","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Venkatsaiakhil","family":"Tirumala","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evan J.","family":"Smith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liang","family":"Xiong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young-Min","family":"Kwon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,1,31]]},"reference":[{"key":"4309_CR1","doi-asserted-by":"publisher","first-page":"780","DOI":"10.2106\/JBJS.F.00222","volume":"89","author":"S Kurtz","year":"2007","unstructured":"Kurtz S, Ong K, Lau E et al (2007) Projections of primary and revision hip and knee arthroplasty in the United States from 2005 to 2030. J Bone Joint Surg Am 89:780\u2013785. https:\/\/doi.org\/10.2106\/JBJS.F.00222","journal-title":"J Bone Joint Surg Am"},{"key":"4309_CR2","doi-asserted-by":"publisher","first-page":"504","DOI":"10.1055\/s-0037-1604152","volume":"31","author":"RK Elmallah","year":"2018","unstructured":"Elmallah RK, Chughtai M, Khlopas A et al (2018) Pain control in total knee arthroplasty. J Knee Surg 31:504\u2013513. https:\/\/doi.org\/10.1055\/s-0037-1604152","journal-title":"J Knee Surg"},{"key":"4309_CR3","doi-asserted-by":"publisher","unstructured":"Arauz P, Klemt C, Limmahakhun S, et al (2018) Stair Climbing and High Knee Flexion Activities in Bi-Cruciate Retaining Total Knee Arthroplasty: In Vivo Kinematics and Articular Contact Analysis. J Arthroplasty. https:\/\/doi.org\/10.1016\/j.arth.2018.11.013","DOI":"10.1016\/j.arth.2018.11.013"},{"key":"4309_CR4","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1007\/s11999-009-1119-9","volume":"468","author":"RB Bourne","year":"2010","unstructured":"Bourne RB, Chesworth BM, Davis AM et al (2010) Patient satisfaction after total knee arthroplasty: who is satisfied and who is not? Clin Orthop Relat Res 468:57\u201363. https:\/\/doi.org\/10.1007\/s11999-009-1119-9","journal-title":"Clin Orthop Relat Res"},{"key":"4309_CR5","doi-asserted-by":"publisher","DOI":"10.1016\/j.arth.2020.08.004","author":"C Klemt","year":"2020","unstructured":"Klemt C, Tirumala V, Smith EJ et al (2020) Development of a preoperative risk calculator for re-infection following revision surgery for periprosthetic joint infection. J Arthroplasty. https:\/\/doi.org\/10.1016\/j.arth.2020.08.004","journal-title":"J Arthroplasty"},{"key":"4309_CR6","doi-asserted-by":"publisher","first-page":"2264","DOI":"10.1016\/j.arth.2015.05.047","volume":"30","author":"DA George","year":"2015","unstructured":"George DA, Konan S, Haddad FS (2015) Single-Stage Hip and Knee Exchange for Periprosthetic Joint Infection. J Arthroplasty 30:2264\u20132270. https:\/\/doi.org\/10.1016\/j.arth.2015.05.047","journal-title":"J Arthroplasty"},{"key":"4309_CR7","doi-asserted-by":"publisher","DOI":"10.1016\/j.arth.2020.07.012","author":"C Klemt","year":"2020","unstructured":"Klemt C, Tirumala V, Oganesyan R et al (2020) Single-stage revision of the infected total knee arthroplasty is associated with improved functional outcomes: A Propensity Score Matched Cohort Study. J Arthroplasty. https:\/\/doi.org\/10.1016\/j.arth.2020.07.012","journal-title":"J Arthroplasty"},{"key":"4309_CR8","doi-asserted-by":"publisher","first-page":"693","DOI":"10.1016\/j.arth.2020.08.004","volume":"36","author":"C Klemt","year":"2021","unstructured":"Klemt C, Tirumala V, Smith EJ et al (2021) Development of a preoperative risk calculator for reinfection following revision surgery for periprosthetic joint infection. J Arthroplasty 36:693\u2013699. https:\/\/doi.org\/10.1016\/j.arth.2020.08.004","journal-title":"J Arthroplasty"},{"key":"4309_CR9","doi-asserted-by":"publisher","first-page":"1309","DOI":"10.1016\/j.arth.2018.02.078","volume":"33","author":"J Parvizi","year":"2018","unstructured":"Parvizi J, Tan TL, Goswami K et al (2018) The 2018 Definition of Periprosthetic Hip and Knee Infection: An Evidence-Based and Validated Criteria. J Arthroplasty 33:1309-1314.e2. https:\/\/doi.org\/10.1016\/j.arth.2018.02.078","journal-title":"J Arthroplasty"},{"key":"4309_CR10","doi-asserted-by":"publisher","first-page":"410","DOI":"10.1080\/00365540410015240","volume":"36","author":"L Bernard","year":"2004","unstructured":"Bernard L, Lubbeke A, Stern R et al (2004) Value of preoperative investigations in diagnosing prosthetic joint infection: retrospective cohort study and literature review. Scand J Infect Dis 36:410\u2013416. https:\/\/doi.org\/10.1080\/00365540410015240","journal-title":"Scand J Infect Dis"},{"key":"4309_CR11","doi-asserted-by":"publisher","first-page":"635","DOI":"10.2106\/JBJS.18.00632","volume":"101","author":"AV Carli","year":"2019","unstructured":"Carli AV, Abdelbary H, Ahmadzai N et al (2019) Diagnostic accuracy of serum, synovial, and tissue testing for chronic periprosthetic joint infection after hip and knee replacements: a systematic review. J Bone Joint Surg Am 101:635\u2013649. https:\/\/doi.org\/10.2106\/JBJS.18.00632","journal-title":"J Bone Joint Surg Am"},{"key":"4309_CR12","doi-asserted-by":"publisher","first-page":"1419","DOI":"10.2106\/JBJS.16.01395","volume":"99","author":"A Shahi","year":"2017","unstructured":"Shahi A, Kheir MM, Tarabichi M et al (2017) Serum D-Dimer test is promising for the diagnosis of periprosthetic joint infection and timing of reimplantation. J Bone Joint Surg Am 99:1419\u20131427. https:\/\/doi.org\/10.2106\/JBJS.16.01395","journal-title":"J Bone Joint Surg Am"},{"key":"4309_CR13","doi-asserted-by":"publisher","first-page":"992","DOI":"10.2106\/JBJS.15.01142","volume":"98","author":"MC Wyatt","year":"2016","unstructured":"Wyatt MC, Beswick AD, Kunutsor SK et al (2016) The alpha-defensin immunoassay and leukocyte esterase colorimetric strip test for the diagnosis of periprosthetic infection: a systematic review and meta-analysis. J Bone Joint Surg Am 98:992\u20131000. https:\/\/doi.org\/10.2106\/JBJS.15.01142","journal-title":"J Bone Joint Surg Am"},{"key":"4309_CR14","doi-asserted-by":"publisher","unstructured":"Sigmund IK, Holinka J, Gamper J, et al (2017) Qualitative alpha-defensin test (Synovasure) for the diagnosis of periprosthetic infection in revision total joint arthroplasty. Bone Joint J 99-B:66\u201372. https:\/\/doi.org\/10.1302\/0301-620X.99B1.BJJ-2016-0295.R1","DOI":"10.1302\/0301-620X.99B1.BJJ-2016-0295.R1"},{"key":"4309_CR15","doi-asserted-by":"publisher","DOI":"10.1016\/j.arth.2019.10.012","author":"T Paziuk","year":"2019","unstructured":"Paziuk T, Rondon AJ, Goswami K et al (2019) A novel adjunct indicator of periprosthetic joint infection: platelet count and mean platelet volume. J Arthroplasty. https:\/\/doi.org\/10.1016\/j.arth.2019.10.012","journal-title":"J Arthroplasty"},{"key":"4309_CR16","doi-asserted-by":"publisher","DOI":"10.1016\/j.arth.2020.07.038","author":"V Tirumala","year":"2020","unstructured":"Tirumala V, Klemt C, Xiong L et al (2020) Diagnostic utility of platelet count\/lymphocyte count ratio and platelet count\/mean platelet volume ratio in periprosthetic joint infection following total knee arthroplasty. J Arthroplasty. https:\/\/doi.org\/10.1016\/j.arth.2020.07.038","journal-title":"J Arthroplasty"},{"key":"4309_CR17","doi-asserted-by":"publisher","DOI":"10.3390\/jcm8050589","author":"NY Kim","year":"2019","unstructured":"Kim NY, Chun D-H, Kim SY et al (2019) Prognostic value of systemic inflammatory indices, NLR, PLR, and MPV, for predicting 1-year survival of patients undergoing cytoreductive surgery with HIPEC. J Clin Med. https:\/\/doi.org\/10.3390\/jcm8050589","journal-title":"J Clin Med"},{"key":"4309_CR18","doi-asserted-by":"publisher","first-page":"1357","DOI":"10.1007\/s10753-013-9675-2","volume":"36","author":"A Ahsen","year":"2013","unstructured":"Ahsen A, Ulu MS, Yuksel S et al (2013) As a new inflammatory marker for familial Mediterranean fever: neutrophil-to-lymphocyte ratio. Inflammation 36:1357\u20131362. https:\/\/doi.org\/10.1007\/s10753-013-9675-2","journal-title":"Inflammation"},{"key":"4309_CR19","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/185317","volume":"2013","author":"AU Uslu","year":"2013","unstructured":"Uslu AU, Deveci K, Korkmaz S et al (2013) Is neutrophil\/lymphocyte ratio associated with subclinical inflammation and amyloidosis in patients with familial Mediterranean fever? Biomed Res Int 2013:185317. https:\/\/doi.org\/10.1155\/2013\/185317","journal-title":"Biomed Res Int"},{"key":"4309_CR20","doi-asserted-by":"publisher","DOI":"10.1111\/eci.13037","volume":"49","author":"GL Erre","year":"2019","unstructured":"Erre GL, Paliogiannis P, Castagna F et al (2019) Meta-analysis of neutrophil-to-lymphocyte and platelet-to-lymphocyte ratio in rheumatoid arthritis. Eur J Clin Invest 49:e13037. https:\/\/doi.org\/10.1111\/eci.13037","journal-title":"Eur J Clin Invest"},{"key":"4309_CR21","doi-asserted-by":"publisher","first-page":"345","DOI":"10.3343\/alm.2019.39.4.345","volume":"39","author":"AY Gasparyan","year":"2019","unstructured":"Gasparyan AY, Ayvazyan L, Mukanova U et al (2019) The Platelet-to-lymphocyte ratio as an inflammatory marker in rheumatic diseases. Ann Lab Med 39:345\u2013357. https:\/\/doi.org\/10.3343\/alm.2019.39.4.345","journal-title":"Ann Lab Med"},{"key":"4309_CR22","doi-asserted-by":"publisher","first-page":"4413","DOI":"10.1177\/0300060519860686","volume":"47","author":"K Gao","year":"2019","unstructured":"Gao K, Zhu W, Liu W et al (2019) Diagnostic value of the blood monocyte-lymphocyte ratio in knee osteoarthritis. J Int Med Res 47:4413\u20134421. https:\/\/doi.org\/10.1177\/0300060519860686","journal-title":"J Int Med Res"},{"key":"4309_CR23","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1016\/j.tranon.2016.10.006","volume":"10","author":"J Xiang","year":"2017","unstructured":"Xiang J, Zhou L, Li X et al (2017) Preoperative monocyte-to-lymphocyte ratio in peripheral blood predicts stages, metastasis, and histological grades in patients with ovarian cancer. Transl Oncol 10:33\u201339. https:\/\/doi.org\/10.1016\/j.tranon.2016.10.006","journal-title":"Transl Oncol"},{"key":"4309_CR24","doi-asserted-by":"publisher","first-page":"1397","DOI":"10.1007\/s00268-016-3427-z","volume":"40","author":"P Vulliamy","year":"2016","unstructured":"Vulliamy P, McCluney S, Mukherjee S et al (2016) Postoperative elevation of the neutrophil: lymphocyte ratio predicts complications following esophageal resection. World J Surg 40:1397\u20131403. https:\/\/doi.org\/10.1007\/s00268-016-3427-z","journal-title":"World J Surg"},{"key":"4309_CR25","doi-asserted-by":"publisher","unstructured":"McNally M, Sousa R, Wouthuyzen-Bakker M, et al (2020) The EBJIS definition of periprosthetic joint infection. Bone Joint J 103-B:18\u201325. https:\/\/doi.org\/10.1302\/0301-620X.103B1.BJJ-2020-1381.R1","DOI":"10.1302\/0301-620X.103B1.BJJ-2020-1381.R1"},{"key":"4309_CR26","doi-asserted-by":"publisher","DOI":"10.1002\/jor.24556","author":"Y Fan","year":"2019","unstructured":"Fan Y, Xiao Y, Sabuhi WA et al (2019) Longitudinal model of periprosthetic joint infection in the rat. J Orthop Res Off Publ Orthop Res Soc. https:\/\/doi.org\/10.1002\/jor.24556","journal-title":"J Orthop Res Off Publ Orthop Res Soc"},{"key":"4309_CR27","doi-asserted-by":"publisher","first-page":"1799","DOI":"10.1038\/s41467-021-22012-7","volume":"12","author":"ZD Aron","year":"2021","unstructured":"Aron ZD, Mehrani A, Hoffer ED et al (2021) trans-Translation inhibitors bind to a novel site on the ribosome and clear Neisseria gonorrhoeae in vivo. Nat Commun 12:1799. https:\/\/doi.org\/10.1038\/s41467-021-22012-7","journal-title":"Nat Commun"},{"key":"4309_CR28","doi-asserted-by":"publisher","first-page":"2082840","DOI":"10.1155\/2018\/2082840","volume":"2018","author":"Q Yang","year":"2018","unstructured":"Yang Q, Zhang P, Wu R et al (2018) Identifying the best marker combination in CEA, CA125, CY211, NSE, and SCC for lung cancer screening by combining ROC curve and logistic regression analyses: is it feasible? Dis Markers 2018:2082840. https:\/\/doi.org\/10.1155\/2018\/2082840","journal-title":"Dis Markers"},{"key":"4309_CR29","doi-asserted-by":"publisher","first-page":"17642","DOI":"10.1074\/jbc.RA119.011181","volume":"294","author":"M Nosrati","year":"2019","unstructured":"Nosrati M, Dey D, Mehrani A et al (2019) Functionally critical residues in the aminoglycoside resistance-associated methyltransferase RmtC play distinct roles in 30S substrate recognition. J Biol Chem 294:17642\u201317653. https:\/\/doi.org\/10.1074\/jbc.RA119.011181","journal-title":"J Biol Chem"},{"key":"4309_CR30","doi-asserted-by":"publisher","first-page":"1007","DOI":"10.1107\/S2052252519012661","volume":"6","author":"JH Mendez","year":"2019","unstructured":"Mendez JH, Mehrani A, Randolph P, Stagg S (2019) Throughput and resolution with a next-generation direct electron detector. IUCrJ 6:1007\u20131013. https:\/\/doi.org\/10.1107\/S2052252519012661","journal-title":"IUCrJ"},{"key":"4309_CR31","doi-asserted-by":"publisher","first-page":"2046","DOI":"10.1007\/s11999-010-1251-6","volume":"468","author":"SM Jafari","year":"2010","unstructured":"Jafari SM, Coyle C, Mortazavi SMJ et al (2010) Revision hip arthroplasty: infection is the most common cause of failure. Clin Orthop Relat Res 468:2046\u20132051. https:\/\/doi.org\/10.1007\/s11999-010-1251-6","journal-title":"Clin Orthop Relat Res"},{"key":"4309_CR32","doi-asserted-by":"publisher","DOI":"10.1016\/j.arth.2020.06.058","author":"Y-M Kwon","year":"2020","unstructured":"Kwon Y-M, Mahajan J, Tirumala V et al (2020) Sensitivity and Specificity of Serum and Synovial Fluid Markers in Diagnosis of Infection in Head-Neck Taper Corrosion of Metal-On-Polyethylene Total Hip Arthroplasty. J Arthroplasty. https:\/\/doi.org\/10.1016\/j.arth.2020.06.058","journal-title":"J Arthroplasty"},{"key":"4309_CR33","unstructured":"Klemt C, Padmanabha A, Esposito JG, et al Elevated ESR and CRP Prior to Second-Stage Reimplantation Knee Revision Surgery for Periprosthetic Joint Infection Are Associated with Increased Reinfection Rates. J Knee Surg"},{"key":"4309_CR34","doi-asserted-by":"publisher","first-page":"156","DOI":"10.7150\/jbji.26401","volume":"3","author":"G Riccio","year":"2018","unstructured":"Riccio G, Cavagnaro L, Akkouche W et al (2018) Qualitative alpha-defensin versus the main available tests for the diagnosis of periprosthetic Joinfile:\/\/\/Users\/christian\/Downloads\/bandj_bjj103-B_1534.rist infection: best predictor test? J bone Jt Infect 3:156\u2013164. https:\/\/doi.org\/10.7150\/jbji.26401","journal-title":"J bone Jt Infect"},{"key":"4309_CR35","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1302\/2046-3758.71.BJR-2017-0323","volume":"7","author":"A Saleh","year":"2018","unstructured":"Saleh A, George J, Faour M et al (2018) Serum biomarkers in periprosthetic joint infections. Bone Joint Res 7:85\u201393. https:\/\/doi.org\/10.1302\/2046-3758.71.BJR-2017-0323","journal-title":"Bone Joint Res"},{"key":"4309_CR36","doi-asserted-by":"publisher","first-page":"408","DOI":"10.1007\/s11999-016-4906-0","volume":"475","author":"T Bonanzinga","year":"2017","unstructured":"Bonanzinga T, Zahar A, D\u00fctsch M et al (2017) How reliable is the alpha-defensin immunoassay test for diagnosing periprosthetic joint infection? a prospective study. Clin Orthop Relat Res 475:408\u2013415. https:\/\/doi.org\/10.1007\/s11999-016-4906-0","journal-title":"Clin Orthop Relat Res"},{"key":"4309_CR37","doi-asserted-by":"publisher","first-page":"604","DOI":"10.1136\/pgmj.2004.030544","volume":"81","author":"E Unsal","year":"2005","unstructured":"Unsal E, Aksaray S, Koksal D, Sipit T (2005) Potential role of interleukin 6 in reactive thrombocytosis and acute phase response in pulmonary tuberculosis. Postgrad Med J 81:604\u2013607. https:\/\/doi.org\/10.1136\/pgmj.2004.030544","journal-title":"Postgrad Med J"},{"key":"4309_CR38","doi-asserted-by":"publisher","first-page":"1670","DOI":"10.1016\/j.arth.2019.04.012","volume":"34","author":"R Malpani","year":"2019","unstructured":"Malpani R, Haynes MS, Clark MG et al (2019) Abnormally high, as well as low, preoperative platelet counts correlate with adverse outcomes and readmissions after elective total knee arthroplasty. J Arthroplasty 34:1670\u20131676. https:\/\/doi.org\/10.1016\/j.arth.2019.04.012","journal-title":"J Arthroplasty"},{"key":"4309_CR39","doi-asserted-by":"publisher","first-page":"8802","DOI":"10.1038\/s41598-018-27198-3","volume":"8","author":"SM Klim","year":"2018","unstructured":"Klim SM, Amerstorfer F, Gruber G et al (2018) Fibrinogen - a practical and cost efficient biomarker for detecting periprosthetic joint infection. Sci Rep 8:8802. https:\/\/doi.org\/10.1038\/s41598-018-27198-3","journal-title":"Sci Rep"},{"key":"4309_CR40","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1186\/s13018-018-0745-x","volume":"13","author":"C Yao","year":"2018","unstructured":"Yao C, Zhang Z, Yao Y et al (2018) Predictive value of neutrophil to lymphocyte ratio and platelet to lymphocyte ratio for acute deep vein thrombosis after total joint arthroplasty: a retrospective study. J Orthop Surg Res 13:40. https:\/\/doi.org\/10.1186\/s13018-018-0745-x","journal-title":"J Orthop Surg Res"},{"key":"4309_CR41","doi-asserted-by":"publisher","first-page":"2737","DOI":"10.2147\/COPD.S111254","volume":"11","author":"G Chen","year":"2016","unstructured":"Chen G, Wu C, Luo Z et al (2016) Platelet-lymphocyte ratios: a potential marker for pulmonary tuberculosis diagnosis in COPD patients. Int J Chron Obstruct Pulmon Dis 11:2737\u20132740. https:\/\/doi.org\/10.2147\/COPD.S111254","journal-title":"Int J Chron Obstruct Pulmon Dis"},{"key":"4309_CR42","doi-asserted-by":"publisher","first-page":"218","DOI":"10.4328\/JCAM.3918","volume":"7","author":"UH G\u00f6lge","year":"2016","unstructured":"G\u00f6lge UH, Kaymaz B, Pazarc\u0131 \u00d6 et al (2016) N\u00f6trofil Lenfosit Orani Protezli Eklem Enfeksiyonlarinda Tan\u0131sal Belirte\u00e7 Olabilir. J Clin Anal Med 7:218\u2013221. https:\/\/doi.org\/10.4328\/JCAM.3918","journal-title":"J Clin Anal Med"},{"key":"4309_CR43","doi-asserted-by":"publisher","first-page":"837","DOI":"10.1007\/s00264-020-04889-z","volume":"45","author":"IK Sigmund","year":"2021","unstructured":"Sigmund IK, Holinka J, Staats K et al (2021) Inferior performance of established and novel serum inflammatory markers in diagnosing periprosthetic joint infections. Int Orthop 45:837\u2013846. https:\/\/doi.org\/10.1007\/s00264-020-04889-z","journal-title":"Int Orthop"},{"key":"4309_CR44","doi-asserted-by":"publisher","first-page":"2533","DOI":"10.2147\/IDR.S184877","volume":"11","author":"Z Zhang","year":"2018","unstructured":"Zhang Z, Ji Y, Wang Z et al (2018) The association between platelet indices and deep surgical site infection after open induction internal fixation for traumatic limb fractures. Infect Drug Resist 11:2533\u20132538. https:\/\/doi.org\/10.2147\/IDR.S184877","journal-title":"Infect Drug Resist"},{"key":"4309_CR45","doi-asserted-by":"publisher","first-page":"148","DOI":"10.1136\/svn-2018-000180","volume":"4","author":"S Li","year":"2019","unstructured":"Li S, Liu K, Zhang R et al (2019) Lower lymphocyte to monocyte ratio is a potential predictor of poor outcome in patients with cerebral venous sinus thrombosis. Stroke Vasc Neurol 4:148\u2013153. https:\/\/doi.org\/10.1136\/svn-2018-000180","journal-title":"Stroke Vasc Neurol"},{"key":"4309_CR46","doi-asserted-by":"publisher","first-page":"1263","DOI":"10.2217\/bmm-2018-0423","volume":"13","author":"Y Lin","year":"2019","unstructured":"Lin Y, Peng Y, Chen Y et al (2019) Association of lymphocyte to monocyte ratio and risk of in-hospital mortality in patients with acute type A aortic dissection. Biomark Med 13:1263\u20131272. https:\/\/doi.org\/10.2217\/bmm-2018-0423","journal-title":"Biomark Med"},{"key":"4309_CR47","doi-asserted-by":"publisher","first-page":"289","DOI":"10.7150\/jca.13432","volume":"7","author":"WK Eo","year":"2016","unstructured":"Eo WK, Chang HJ, Kwon SH et al (2016) The lymphocyte-monocyte ratio predicts patient survival and aggressiveness of ovarian cancer. J Cancer 7:289\u2013296. https:\/\/doi.org\/10.7150\/jca.13432","journal-title":"J Cancer"},{"key":"4309_CR48","doi-asserted-by":"publisher","first-page":"2519","DOI":"10.3748\/wjg.v23.i14.2519","volume":"23","author":"K Inaoka","year":"2017","unstructured":"Inaoka K, Kanda M, Uda H et al (2017) Clinical utility of the platelet-lymphocyte ratio as a predictor of postoperative complications after radical gastrectomy for clinical T2\u20134 gastric cancer. World J Gastroenterol 23:2519\u20132526. https:\/\/doi.org\/10.3748\/wjg.v23.i14.2519","journal-title":"World J Gastroenterol"},{"key":"4309_CR49","doi-asserted-by":"publisher","unstructured":"Xu H, Xie J-W, Liu L, et al (2021) Combination of CRP with NLR is a sensitive tool for screening fixation-related infection in patients undergoing conversion total hip arthroplasty after failed internal fixation for femoral neck fracture. Bone Joint J 103-B:1534\u20131540. https:\/\/doi.org\/10.1302\/0301-620X.103B.BJJ-2021-0105.R1","DOI":"10.1302\/0301-620X.103B.BJJ-2021-0105.R1"}],"container-title":["Archives of Orthopaedic and Trauma Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00402-021-04309-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00402-021-04309-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00402-021-04309-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,24]],"date-time":"2023-02-24T11:09:06Z","timestamp":1677236946000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00402-021-04309-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1,31]]},"references-count":49,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2023,3]]}},"alternative-id":["4309"],"URL":"https:\/\/doi.org\/10.1007\/s00402-021-04309-w","relation":{},"ISSN":["1434-3916"],"issn-type":[{"value":"1434-3916","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,1,31]]},"assertion":[{"value":"4 December 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 December 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"31 January 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors have no relevant financial or non-financial interests to disclose. The authors have no conflicts of interest to declare that are relevant to the content of this article. All authors certify that they have no affiliations with or involvement in any organization or entity with any financial interest or non-financial interest in the subject matter or materials discussed in this manuscript. The authors have no financial or proprietary interests in any material discussed in this article.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This article does not contain any studies with human participants or animals performed by any of the authors.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Informed consent was obtained for the retrospective patient chart review.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}