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The aim of the study was to assess the epidemiology of isolated metatarsal fractures in an adult population at a level-1 trauma centre.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>Radiological and clinical databases were searched for a five-year period. Eligible were all patients with acute isolated metatarsal fractures over the age of 18\u00a0years with radiographs in two planes available. Stress fractures, injuries affecting Lisfranc joint stability, and concomitant injuries to other regions than the metatarsals were excluded. Data collection included general demographics, mechanism of injury, season of the trauma and fracture details.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Out of 3259 patients, 642 patients met the inclusion criteria and were included for the analysis. The patients\u2019 mean age was 44.5\u2009\u00b1\u200918.9\u00a0years, 50.6% were female. 83.3% suffered an isolated, 16.7% multiple metatarsal fractures. Single metatarsal fractures occurred predominantly at the fifth metatarsal bone (81.3%), their frequency decreased with increasing age, with a seasonal peak during the summer. Patients suffering multiple metatarsal fractures were significantly older (51.6\u2009\u00b1\u200921.2 vs. 43.0\u2009\u00b1\u200918.1\u00a0years;<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) and the injury resulted significantly more often from a high-energy trauma (6.7% vs. 23.4%;<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). Multiple metatarsal fractures occurred evenly throughout all metatarsals but revealed a focus on female population with no seasonal differences.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Single metatarsal fractures predominantly occurred at the fifth metatarsal bone and showed a seasonal, gender and age dependency. Multiple metatarsal fractures were homogeneously distributed between the different metatarsals with distinct age-dependent gender differences.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of evidence<\/jats:title><jats:p>Level III.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00402-022-04396-3","type":"journal-article","created":{"date-parts":[[2022,3,2]],"date-time":"2022-03-02T10:03:43Z","timestamp":1646215423000},"page":"1939-1945","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Acute, isolated fractures of the metatarsal bones: an epidemiologic study"],"prefix":"10.1007","volume":"143","author":[{"given":"Viktoria","family":"Herterich","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luzie","family":"Hofmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wolfgang","family":"B\u00f6cker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6713-4017","authenticated-orcid":false,"given":"Hans","family":"Polzer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastian Felix","family":"Baumbach","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,3,2]]},"reference":[{"issue":"1","key":"4396_CR1","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1177\/1071100720953083","volume":"42","author":"BA Bean","year":"2021","unstructured":"Bean BA, Smyth NA, Abbasi P, Parks BG, Hembree WC (2021) Biomechanical comparison of hook plate vs headless compression screw fixation of large fifth metatarsal base avulsion fractures. 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ICMJE forms for all authors are available online.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The study was approved by the local ethic committee. The study was performed at Department of Orthopaedics and Trauma Surgery, Musculoskeletal University Center Munich (MUM), University Hospital, LMU Munich.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}