{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T15:16:21Z","timestamp":1782314181137,"version":"3.54.5"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2022,9,9]],"date-time":"2022-09-09T00:00:00Z","timestamp":1662681600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2022,9,9]],"date-time":"2022-09-09T00:00:00Z","timestamp":1662681600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Arch Orthop Trauma Surg"],"DOI":"10.1007\/s00402-022-04586-z","type":"journal-article","created":{"date-parts":[[2022,9,9]],"date-time":"2022-09-09T12:37:36Z","timestamp":1662727056000},"page":"3803-3809","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Incidence of complications\u00a0and revision\u00a0surgery in HAART\u00a0compliant HIV patients undergoing primary\u00a0total hip and knee arthroplasty: an institutional review"],"prefix":"10.1007","volume":"143","author":[{"given":"Roshan","family":"Jacob","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelly","family":"Chandler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nick","family":"Medawar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mackenzie","family":"Sowers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerald","family":"McGwin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sameer","family":"Naranje","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,9,9]]},"reference":[{"key":"4586_CR1","doi-asserted-by":"publisher","first-page":"1254","DOI":"10.1016\/j.arth.2012.12.021","volume":"28","author":"BM Capogna","year":"2013","unstructured":"Capogna BM, Lovy A, Blum Y, Kim SJ, Felsen UR, Geller DS (2013) Infection rate following total joint arthroplasty in the HIV population. J Arthroplasty 28:1254\u20131258","journal-title":"J Arthroplasty"},{"key":"4586_CR2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0024876","volume":"6","author":"NW Cummins","year":"2011","unstructured":"Cummins NW, Klicpera A, Sainski AM, Bren GD, Khosla S, Westendorf JJ, Badley AD (2011) Human immunodeficiency virus envelope protein Gp120 induces proliferation but not apoptosis in osteoblasts at physiologic concentrations. PLoS ONE 6:e24876","journal-title":"PLoS ONE"},{"key":"4586_CR3","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.RVW.17.00029","volume":"5","author":"D Dimitriou","year":"2017","unstructured":"Dimitriou D, Ramokgopa M, Pietrzak JRT, van der Jagt D, Mokete L (2017) Human immunodeficiency virus infection and hip and knee arthroplasty. JBJS Rev 5:e8","journal-title":"JBJS Rev"},{"key":"4586_CR4","doi-asserted-by":"publisher","first-page":"5074923","DOI":"10.1155\/2018\/5074923","volume":"2018","author":"P Echeverr\u00eda","year":"2018","unstructured":"Echeverr\u00eda P, Bonjoch A, Puig J, Estany C, Ornelas A, Clotet B, Negredo E (2018) High prevalence of sarcopenia in HIV-infected individuals. Biomed Res Int 2018:5074923","journal-title":"Biomed Res Int"},{"key":"4586_CR5","doi-asserted-by":"publisher","first-page":"2146","DOI":"10.1016\/j.arth.2016.02.058","volume":"31","author":"MA Enayatollahi","year":"2016","unstructured":"Enayatollahi MA, Murphy D, Maltenfort MG, Parvizi J (2016) Human immunodeficiency virus and total joint arthroplasty: the risk for infection is reduced. J Arthroplasty 31:2146\u20132151","journal-title":"J Arthroplasty"},{"key":"4586_CR6","first-page":"102","volume":"34","author":"J Falakassa","year":"2014","unstructured":"Falakassa J, Diaz A, Schneiderbauer M (2014) Outcomes of total joint arthroplasty in HIV patients. Iowa Orthop J 34:102\u2013106","journal-title":"Iowa Orthop J"},{"key":"4586_CR7","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1016\/j.bbrc.2010.02.080","volume":"394","author":"IF Grigsby","year":"2010","unstructured":"Grigsby IF, Pham L, Mansky LM, Gopalakrishnan R, Carlson AE, Mansky KC (2010) Tenofovir treatment of primary osteoblasts alters gene expression profiles: implications for bone mineral density loss. Biochem Biophys Res Commun 394:48\u201353","journal-title":"Biochem Biophys Res Commun"},{"key":"4586_CR8","doi-asserted-by":"publisher","first-page":"1050","DOI":"10.1302\/0301-620X.83B7.0831050","volume":"83","author":"JL Hicks","year":"2001","unstructured":"Hicks JL, Ribbans WJ, Buzzard B, Kelley SS, Toft L, Torri G, Wiedel JD, York J (2001) Infected joint replacements in HIV-positive patients with haemophilia. J Bone Joint Surg Br 83:1050\u20131054","journal-title":"J Bone Joint Surg Br"},{"issue":"20","key":"4586_CR9","doi-asserted-by":"publisher","first-page":"1845","DOI":"10.2106\/JBJS.L.01583","volume":"95","author":"K Issa","year":"2013","unstructured":"Issa K, Naziri Q, Rasquinha V, Maheshwari AV, Delanois RE, Mont MA (2013) Outcomes of cementless primary THA for osteonecrosis in HIV-infected patients. J Bone Joint Surg Am 95(20):1845\u20131850. https:\/\/doi.org\/10.2106\/JBJS.L.01583","journal-title":"J Bone Joint Surg Am"},{"key":"4586_CR10","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1007\/978-981-13-0484-2_6","volume":"1075","author":"M Kumi Smith","year":"2018","unstructured":"Kumi Smith M, Jewell BL, Hallett TB, Cohen MS (2018) Treatment of HIV for the Prevention of Transmission in Discordant Couples and at the Population Level. Adv Exp Med Biol 1075:125\u2013162. https:\/\/doi.org\/10.1007\/978-981-13-0484-2_6","journal-title":"Adv Exp Med Biol"},{"issue":"3","key":"4586_CR11","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1302\/0301-620X.93B3.25467","volume":"93","author":"G Labek","year":"2011","unstructured":"Labek G, Thaler M, Janda W, Agreiter M, St\u00f6ckl B (2011) Revision rates after total joint replacement: cumulative results from worldwide joint register datasets. J Bone Joint Surg Br 93(3):293-297. https:\/\/doi.org\/10.1302\/0301-620X.93B3.25467 (Erratum in: J Bone Joint Surg Br. 2011 Jul;93(7):998. PMID: 21357948)","journal-title":"J Bone Joint Surg Br"},{"key":"4586_CR12","doi-asserted-by":"publisher","first-page":"330","DOI":"10.1054\/arth.2001.21454","volume":"16","author":"CR Lehman","year":"2001","unstructured":"Lehman CR, Ries MD, Paiement GD, Davidson AB (2001) Infection after total joint arthroplasty in patients with human immunodeficiency virus or intravenous drug use. J Arthroplasty 16:330\u2013335","journal-title":"J Arthroplasty"},{"issue":"11","key":"4586_CR13","doi-asserted-by":"publisher","first-page":"1028","DOI":"10.2106\/JBJS.L.00269","volume":"95","author":"CA Lin","year":"2013","unstructured":"Lin CA, Kuo AC, Takemoto S (2013) Comorbidities and perioperative complications in HIV-positive patients undergoing primary total hip and knee arthroplasty. J Bone Joint Surg 95(11):1028\u20131036. https:\/\/doi.org\/10.2106\/JBJS.L.00269","journal-title":"J Bone Joint Surg"},{"key":"4586_CR14","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1016\/j.arth.2013.06.015","volume":"29","author":"CA Lin","year":"2014","unstructured":"Lin CA, Takemoto S, Kandemir U, Kuo AC (2014) Mid-term outcomes in HIV-positive patients after primary total hip or knee arthroplasty. J Arthroplasty 29:277\u2013282","journal-title":"J Arthroplasty"},{"key":"4586_CR15","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1186\/s12891-019-2573-5","volume":"20","author":"Y Liu","year":"2019","unstructured":"Liu Y, Foreman SC, Joseph GB, Neumann J, Tien PC, Li X, Lane NE, Nevitt MC, McCulloch CE, Link TM (2019) Is treated HIV infection associated with knee cartilage degeneration and structural changes? A longitudinal study using data from the osteoarthritis initiative. BMC Musculoskelet Disord 20:190","journal-title":"BMC Musculoskelet Disord"},{"key":"4586_CR16","doi-asserted-by":"publisher","first-page":"522","DOI":"10.1016\/j.arth.2018.11.001","volume":"34","author":"D Novikov","year":"2019","unstructured":"Novikov D, Anoushiravani AA, Chen KK, Wolfson TS, Snir N, Schwarzkopf R (2019) Total hip arthroplasty in human immunodeficiency virus-positive patients: a concise follow-up at 10\u201314 years. J Arthroplasty 34:522\u2013526","journal-title":"J Arthroplasty"},{"key":"4586_CR17","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1054\/arth.2003.50094","volume":"18","author":"J Parvizi","year":"2003","unstructured":"Parvizi J, Sullivan TA, Pagnano MW, Trousdale RT, Bolander ME (2003) Total joint arthroplasty in human immunodeficiency virus-positive patients: an alarming rate of early failure. J Arthroplasty 18:259\u2013264","journal-title":"J Arthroplasty"},{"key":"4586_CR18","doi-asserted-by":"publisher","first-page":"446","DOI":"10.2484\/rcr.v5i4.446","volume":"5","author":"J Petscavage","year":"2010","unstructured":"Petscavage J, Chew FS (2010) Hoffa\u2019s fat-pad inflammation in an HIV-positive patient. Radiol case reports 5:446","journal-title":"Radiol case reports"},{"key":"4586_CR19","doi-asserted-by":"publisher","first-page":"164","DOI":"10.1302\/2058-5241.5.190030","volume":"5","author":"JRT Pietrzak","year":"2020","unstructured":"Pietrzak JRT, Maharaj Z, Mokete L, Sikhauli N (2020) Human immunodeficiency virus in total hip arthroplasty. EFORT open Rev 5:164\u2013171","journal-title":"EFORT open Rev"},{"key":"4586_CR20","doi-asserted-by":"publisher","first-page":"1710","DOI":"10.1007\/s11999-008-0209-4","volume":"466","author":"L Pulido","year":"2008","unstructured":"Pulido L, Ghanem E, Joshi A, Purtill JJ, Parvizi J (2008) Periprosthetic joint infection: the incidence, timing, and predisposing factors. Clin Orthop Relat Res 466:1710\u20131715","journal-title":"Clin Orthop Relat Res"},{"key":"4586_CR21","doi-asserted-by":"publisher","first-page":"716","DOI":"10.1016\/S0883-5403(05)80065-8","volume":"10","author":"MV Ragni","year":"1995","unstructured":"Ragni MV, Crossett LS, Herndon JH (1995) Postoperative infection following orthopaedic surgery in human immunodeficiency virus-infected hemophiliacs with CD4 counts < or = 200\/mm3. J Arthroplasty 10:716\u2013721","journal-title":"J Arthroplasty"},{"key":"4586_CR22","doi-asserted-by":"publisher","first-page":"593","DOI":"10.1016\/j.arth.2020.08.021","volume":"36","author":"S Rajcoomar","year":"2021","unstructured":"Rajcoomar S, Rajcoomar R, Rafferty M, van der Jagt D, Mokete L, Pietrzak JRT (2021) Good functional outcomes and low infection rates in total hip arthroplasty in HIV-positive patients, provided there is strict compliance with highly active antiretroviral therapy. J Arthroplasty 36:593\u2013599","journal-title":"J Arthroplasty"},{"key":"4586_CR23","doi-asserted-by":"publisher","first-page":"483","DOI":"10.1080\/110241598750005813","volume":"164","author":"D Savioz","year":"1998","unstructured":"Savioz D, Chilcott M, Ludwig C, Savioz M, Kaiser L, Leissing C, B\u00fchler L, Peter R, Morel P (1998) Preoperative counts of CD4 T-lymphocytes and early postoperative infective complications in HIV-positive patients. Eur J Surg 164:483\u2013487","journal-title":"Eur J Surg"},{"key":"4586_CR24","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1016\/j.artd.2017.05.003","volume":"3","author":"BD Springer","year":"2017","unstructured":"Springer BD, Cahue S, Etkin CD, Lewallen DG, McGrory BJ (2017) Infection burden in total hip and knee arthroplasties: an international registry-based perspective. Arthroplast today 3:137\u2013140","journal-title":"Arthroplast today"},{"key":"4586_CR25","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1111\/os.12001","volume":"4","author":"S Swensen","year":"2012","unstructured":"Swensen S, Schwarzkopf R (2012) Total joint arthroplasty in human immunodeficiency virus positive patients. Orthop Surg 4:211\u2013215","journal-title":"Orthop Surg"},{"key":"4586_CR26","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1016\/j.emc.2010.01.009","volume":"28","author":"SS Takhar","year":"2010","unstructured":"Takhar SS, Hendey GW (2010) Orthopedic illnesses in patients with HIV. Emerg Med Clin North Am 28:335\u2013342 (Table of Contents)","journal-title":"Emerg Med Clin North Am"},{"key":"4586_CR27","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1004497","volume":"10","author":"K Titanji","year":"2014","unstructured":"Titanji K, Vunnava A, Sheth AN, Delille C, Lennox JL, Sanford SE, Foster A, Knezevic A, Easley KA, Weitzmann MN, Ofotokun I (2014) Dysregulated B cell expression of RANKL and OPG correlates with loss of bone mineral density in HIV infection. PLoS Pathog 10:e1004497","journal-title":"PLoS Pathog"},{"key":"4586_CR28","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1007\/s00256-006-0201-6","volume":"36","author":"H Torshizy","year":"2007","unstructured":"Torshizy H, Pathria MN, Chung CB (2007) Inflammation of Hoffa\u2019s fat pad in the setting of HIV: magnetic resonance imaging findings in six patients. Skeletal Radiol 36:35\u201340","journal-title":"Skeletal Radiol"},{"key":"4586_CR29","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1016\/s0002-9610(00)00450-5","volume":"180","author":"HS Tran","year":"2000","unstructured":"Tran HS, Moncure M, Tarnoff M, Goodman M, Puc MM, Kroon D, Eydelman J, Ross SE (2000) Predictors of operative outcome in patients with human immunodeficiency virus infection and acquired immunodeficiency syndrome. Am J Surg 180:228\u2013233. https:\/\/doi.org\/10.1016\/s0002-9610(00)00450-5","journal-title":"Am J Surg"}],"container-title":["Archives of Orthopaedic and Trauma Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00402-022-04586-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00402-022-04586-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00402-022-04586-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,26]],"date-time":"2023-06-26T19:06:26Z","timestamp":1687806386000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00402-022-04586-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,9]]},"references-count":29,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2023,7]]}},"alternative-id":["4586"],"URL":"https:\/\/doi.org\/10.1007\/s00402-022-04586-z","relation":{},"ISSN":["1434-3916"],"issn-type":[{"value":"1434-3916","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,9,9]]},"assertion":[{"value":"22 February 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 August 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 September 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The Authors have not published, posted, or submitted any other papers from this study. The authors have no disclosures or conflicts of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Ethical approval was granted by UAB Institutional Review Board for this study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Informed consent was not required for this study as per our institution\u2019s IRB.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}