{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T17:49:28Z","timestamp":1790876968886,"version":"4.1.0"},"reference-count":36,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2023,1,11]],"date-time":"2023-01-11T00:00:00Z","timestamp":1673395200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2023,1,11]],"date-time":"2023-01-11T00:00:00Z","timestamp":1673395200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Johannes Kepler University Linz"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Arch Orthop Trauma Surg"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Introduction<\/jats:title>\n                <jats:p>Increased risk of periprosthetic joint infection (PJI) in minimally invasive (MIS) total hip arthroplasty (THA) is still debated. This study aimed to identify differences in surgical and patient-related risk factors for PJI between an MIS anterolateral approach and transgluteal-modified Hardinge approach.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>A retrospective cohort of 5315 THAs performed between 2006 and 2019 at a single institution was screened. Short stem THAs performed via an MIS anterolateral approach in the supine position and standard straight stem THAs performed via a transgluteal modified Hardinge approach were included. Propensity score matching was performed to control for selection bias. After matching, 1405 (34.3%) short stem THAs implanted via MIS anterolateral approach and 2687 (65.7%) straight stem THAs implanted via a transgluteal modified Hardinge approach were included. The risk of PJI due to patient-specific and surgical factors was retrospectively analyzed using chi-square test and multivariate regression analysis.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>PJI occurred in 1.1% in both MIS anterolateral and transgluteal approach (<jats:italic>p<\/jats:italic>\u2009=\u20090.823). Multivariate regression showed an increased infection risk for patients with a BMI between 35 and 39.99\u00a0kg\/m<jats:sup>2<\/jats:sup> (OR 6.696; CI 1.799\u201324.923; <jats:italic>p<\/jats:italic>\u2009=\u20090.005), which could not be demonstrated for transgluteal approach (OR 0.900; CI 0.900\u20134.144; <jats:italic>p<\/jats:italic>\u2009=\u20090.93). A BMI\u2009\u2265\u200940\u00a0kg\/m<jats:sup>2<\/jats:sup> (OR 14.150; CI 2.416\u201382.879; <jats:italic>p<\/jats:italic>\u2009=\u20090.003) was detected as a risk factor for PJI only in anterolateral approach. Increased operation time\u2009\u2265\u2009121\u00a0min showed a significantly increased risk for PJI in the general cohort (OR 6.989; CI1.286\u201337.972; <jats:italic>p<\/jats:italic>\u2009=\u20090.024).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Minimally invasive anterolateral and transgluteal THA show a comparable rate of early PJI within the first year of index surgery. A BMI of\u2009\u2265\u200935\u00a0kg\/m<jats:sup>2<\/jats:sup> was detected as a clear risk factor for infection in the anterolateral approach. Prolonged operation time\u2009\u2265\u2009121\u00a0min increases the risk of PJI regardless of approach.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00402-022-04756-z","type":"journal-article","created":{"date-parts":[[2023,1,11]],"date-time":"2023-01-11T05:02:48Z","timestamp":1673413368000},"page":"5405-5415","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["A propensity score-matched analysis on the impact of patient and surgical factors on early periprosthetic joint infection in minimally invasive anterolateral and transgluteal total hip arthroplasty"],"prefix":"10.1007","volume":"143","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4708-5254","authenticated-orcid":false,"given":"Matthias","family":"Luger","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcel","family":"de Vries","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra","family":"Feldler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G\u00fcnter","family":"Hipmair","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tobias","family":"Gotterbarm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Klasan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,1,11]]},"reference":[{"issue":"9597","key":"4756_CR1","doi-asserted-by":"publisher","first-page":"1508","DOI":"10.1016\/S0140-6736(07)60457-7","volume":"370","author":"ID Learmonth","year":"2007","unstructured":"Learmonth ID, Young C, Rorabeck C (2007) The operation of the century: total hip replacement. 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We report personal fees paid to one co-author (T.G.) during the conduct of the study from Zimmer Biomet, Europe and from Depuy Synthes Orthop\u00e4die Gmbh, Peter Brehm GmbH, ImplanTec GmbH outside the submitted work. We report research grants paid to our institution during the conduct of the study from Zimmer Biomet, Europe, Mathys AG Switzerland, Anika Therapeutics outside the submitted work.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This study received ethical approval from the local institutional review board (EK-No.: 1194\/2021) of the \u201cEthikkommission O\u00d6\u201d of the Johannes Kepler University Linz (JKU Linz).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and\/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. Informed consent was not required because of the retrospective study design.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}},{"value":"The study was approved by the institutional review board (EK-No.: 1239\/2019) in accordance with the World Medical Association Declaration of Helsinki. Because of the retrospective evaluation of pre-existing medical records informed consent was not required.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and\/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. Informed consent for publishment was not required because of the retrospective study design.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to publish"}}]}}