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Effect estimates were pooled across studies using random effects models. Results were presented as weighted risk ratio (RR) or weighted mean difference (MD) with corresponding 95% confidence interval (95% CI).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Five RCTs (397 patients) and 14 observational studies (21,396 patients) were included. No significant differences in functional outcomes, complications, or surgical outcomes were found between extramedullary and intramedullary fixation devices, except for a difference in duration of surgery (MD 14.1\u00a0min, CI 5.76\u201322.33, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) and intra-operative blood loss (MD 92.30\u00a0mL, CI 13.49\u2013171.12, <jats:italic>p<\/jats:italic>\u2009=\u20090.02), favoring intramedullary fixation.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Current literature shows no meaningful differences in complications, surgical, or functional outcomes between extramedullary and intramedullary fixation of stable two-part trochanteric femoral fractures. Both treatment options result in good outcomes. This study implicates that, costs should be taken into account when considering implants or comparing fixation methods in future research.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00402-023-04902-1","type":"journal-article","created":{"date-parts":[[2023,5,2]],"date-time":"2023-05-02T14:52:55Z","timestamp":1683039175000},"page":"5065-5083","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Extramedullary versus intramedullary fixation of stable trochanteric femoral fractures: a systematic review and meta-analysis"],"prefix":"10.1007","volume":"143","author":[{"given":"Miliaan L.","family":"Zeelenberg","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leendert H. T.","family":"Nugteren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. 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