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Clinical outcomes were determined by measuring the 36-Item Short-Form Health Survey (SF-36) and International Knee Documentation Committee (IKDC) scores and the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) values preoperatively and 3, 6, and 12\u00a0months, and a mean of 6\u00a0years postoperatively. At the final follow-up, the Magnetic Resonance Observation of Cartilage Repair Tissue (MOCART) score was evaluated.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Twenty-two patients with 23 focal cartilage defects (19 patella and four trochlea) were available for the final follow-up. The mean defect size was 4.0\u2009\u00b1\u20091.9 cm<jats:sup>2<\/jats:sup> (range 2.4\u20139.4 cm<jats:sup>2<\/jats:sup>). All clinical outcome scores improved significantly until 5\u20137 years after MACI (SF-36 score, 61.2\u2009\u00b1\u200919.6 to 83.2\u2009\u00b1\u200911.6; <jats:italic>P<\/jats:italic>\u2009=\u20090.001; IKDC score, 47.5\u2009\u00b1\u200920.6 to 74.7\u2009\u00b1\u200915.5; <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001; and WOMAC, 29.8\u2009\u00b1\u200915.7 to 8.2\u2009\u00b1\u200910.3; <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). The mean MOCART score was 76.0\u2009\u00b1\u200911.0 at the final follow-up. Nineteen of the 22 patients (86.4%) were satisfied with the outcomes after 5\u20137 years and responded that they would undergo the procedure again.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>MACI in the patellofemoral joint demonstrated good midterm clinical results with a significant reduction in pain, improvement in function, and high patient satisfaction. These clinical findings are supported by radiological evidence from MOCART scores.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Level of evidence<\/jats:title>\n                <jats:p>IV\u2013case series.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00402-023-05179-0","type":"journal-article","created":{"date-parts":[[2024,1,11]],"date-time":"2024-01-11T10:02:25Z","timestamp":1704967345000},"page":"1655-1665","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Treatment of cartilage defects in the patellofemoral joint with matrix-associated autologous chondrocyte implantation effectively improves pain, function, and radiological outcomes after 5\u20137 years"],"prefix":"10.1007","volume":"144","author":[{"given":"Martin","family":"Eichinger","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin","family":"Henninger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin","family":"Petry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philipp","family":"Schuster","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elmar","family":"Herbst","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moritz","family":"Wagner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ralf","family":"Rosenberger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raul","family":"Mayr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,1,11]]},"reference":[{"key":"5179_CR1","doi-asserted-by":"publisher","unstructured":"Minas T (2012) A primer in cartilage repair. 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