{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T09:07:49Z","timestamp":1775034469814,"version":"3.50.1"},"reference-count":34,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,12,12]],"date-time":"2024-12-12T00:00:00Z","timestamp":1733961600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,12,12]],"date-time":"2024-12-12T00:00:00Z","timestamp":1733961600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Universit\u00e4tsklinikum Hamburg-Eppendorf (UKE)"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Arch Orthop Trauma Surg"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Patients with primary hip osteoarthritis undergoing unilateral total hip arthroplasty (THA) often face uncertainty about the future need for arthroplasty in the contralateral hip. We aimed to identify parameters that have predictive value with regard to the necessity for contralateral THA or the development of contralateral radiographic osteoarthritis (OA) phenotypes following index surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and methods<\/jats:title>\n                    <jats:p>In this retrospective study, we analyzed 220 patients undergoing THA. Of these, 24.1% required contralateral THA at a mean follow-up of 18.3months. Our assessments included preoperative and follow-up pelvis radiographs as well as bone mineral density (BMD) measurement by dual-energy X-ray absorptiometry prior to index THA. Comprehensive radiological measurements such as the Kellgren-Lawrence OA grade, osteophyte evaluation as well as joint shape and alignment (including alpha and CE angles) were performed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      We identified three indicators at the initial assessment for predicting the need for contralateral THA: higher BMI (odds ratio (OR) 1.1 [95%-CI 1.0-1.2],\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.033), higher alpha angles (&gt;\u200961.5\u00b0) (OR 2.5 [95%-CI 1.0-6.3],\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.045) and the presence of multiple osteophytes (OR 2.6 [95%-CI 1.4\u20134.9],\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.004). Moreover, higher alpha angles were linked to more severe radiographic OA, especially osteophytosis. Higher BMD T-scores were also associated with progressive formation of multiple and large osteophytes but not joint space narrowing.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Three factors - BMI, alpha angle, and osteophyte number - are key short-term predictors for contralateral THA after index THA. We also identified BMD as a surrogate for osteophyte formation. These findings provide novel and valuable insights for patients and surgeons regarding risks and counseling for contralateral OA and THA.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00402-024-05615-9","type":"journal-article","created":{"date-parts":[[2024,12,12]],"date-time":"2024-12-12T06:47:35Z","timestamp":1733986055000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Short-term prediction of clinical and radiographic contralateral hip osteoarthritis after index total hip arthroplasty"],"prefix":"10.1007","volume":"145","author":[{"given":"Ana","family":"Ocokoljic","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lukas","family":"Krivec","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Assil-Ramin","family":"Alimy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander","family":"Simon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andr\u00e9","family":"Strahl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank Timo","family":"Beil","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1058-1307","authenticated-orcid":false,"given":"Tim","family":"Rolvien","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,12,12]]},"reference":[{"issue":"7","key":"5615_CR1","doi-asserted-by":"publisher","first-page":"1172","DOI":"10.1002\/art.42089","volume":"74","author":"H Long","year":"2022","unstructured":"Long H, Liu Q, Yin H, Wang K, Diao N, Zhang Y, Lin J, Guo A (2022) Prevalence trends of Site-Specific Osteoarthritis from 1990 to 2019: findings from the global burden of Disease Study 2019. 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